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Kharkiv National Medical University
Kharkiv State University
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Yuliia Slynko, Iryna Sokolova, Halyna Gubina-Vakulik, Anatoly Potapchyk, and Iryna Korneyko
APESB (Associacao de Apoio a Pesquisa em Saude Bucal)
Objective: To evaluate of the microstructure of the salivary glands of experimental animals born from of females rats, who were subjected to different modes of motor activity during the pregnancy: limited and compensated by regular moderate training. Material and Methods: The sample was composed 84 three-month-old descendants of Wistar rats which were divided into three groups: G1 (n = 27): posterity of female rats, who during gestation were in standard conditions; G2 (n = 25): posterity of female rats, who during pregnancy were in hypokinesia conditions; G3 (n = 32): which stayed in conditions of hypokinesia, but had running load in running wheel regularly 5 times a week. Results: In adult descendants of G2, morphological structure of the submandibular salivary glands was characterized by decrease size and number of glandular cells; reduction of their cytoplasm; increase in heterochromatin amount and decrease in the intensity of fuchsinophilia. Microstructure of the submandibular salivary glands of the offspring of G3 indicates positive effect of regular short-term physical activity on the morphofunctional state of the specified glands. An increased number of tissue basophils in their stroma is also in favor of greater functional activity of salivary glands. Conclusion: This study indicates deceleration of the metabolic processes in salivary glands of animals under the influence of hypokinesia of their mothers during pregnancy. It was also confirmed that regular physical activity completely eliminates the negative effect of mothers' hypokinesia on morphology the salivary glands of the descendant.
Iryna Sorokina, Tetyana Ospanova, Mykhailo Myroshnychenko, Iryna Korneyko, , , , and
Knowledge E
Background: The state of the mother health is of great importance in the development of children renal pathology. Objective: To reveal macroscopic features of the fetuses and newborns kidneys of the mothers whose pregnancy was complicated by preeclampsia. Materials and Methods: The study involved the kidneys of 106 full-term fetuses and newborns of mothers with physiological pregnancy, complicated pregnancy by preeclampsia. During the autopsies, the shape, texture, surface, color were assessed in each kidney, and then its weight, length, width and thickness were measured. Results: The kidneys in fetuses and newborns from mothers with severe preeclampsia were characterized by a more pronounced lobulation. In fetuses and newborns from mothers with mild preeclampsia, the mass of the left kidney prevailed over the mass of the right kidney. The organometric kidney values were greater in newborns compared to fetuses in the cases of complicated by mild and moderate preeclampsia maternal pregnancy. Conclusion: Maternal moderate and severe preeclampsia delay renal growth in fetuses and newborns that manifest by a reduction of the kidneys organometric parameters.