ETCHEBEST
Sciences Faculty Université de Paris · UMR-S1134
Research Interests
Membrane Protein Systems, Molecular Mechanisms, Biophysics, Molecular Modelling, Structural Bioinformatics.
Biography
1982: CNRS Researcher, Theoretical Biochemistry Laboratory, IBPC, Paris. 1999-Present: Professor University Paris-Diderot, Biochemistry and Life Sciences Department. 1999-2005: Member of UMR-S726, “Genomics Bioinformatics and Molecular Modelling” (EBGM). Molecular Modelling group leader 2005-2008: Director of UMR-S726. 2009-2018: Team Leader of DSIMB, “Dynamic of Structures and Interactions of Macromolecules in Biology” UMR_S1134” Integrated Red Blood Cell Physiology. University Paris Diderot-Inserm and Institut National de la Transfusion Sanguine (INTS) 2019-Present: Leader of Molecular Modelling Group in DSIMB. Responsibilities at the University and National Institutions. 2004-2008: Vice-President of the French Biophysical Society. 2014-2019: Vice President of French National Board of Universities (CNU) Section “Biochemistry and Molecular Biology”.
Education
1979 Maîtrise Physical-Chemistry (Eq. Bachelor Degree) Pierre et Marie Curie-Paris VI University 1980 DEA Physical-Chemistry (Eq. Master Degree) Pierre et Marie Curie-Paris VI University 1983 3rd Cycle Doctorate Physical-Chemistry (Eq. PhD) Pierre et Marie Curie-Paris VI University 1987 State Doctorate (Eq. Habilitation) Pierre et Marie Curie-Paris VI University
Recent Scopus Publications
- Conformational dynamics study of TfR1 upon transferrin binding via NMA and MD simulations
- ANABAG: Annotated Antibody–Antigen Data Set with Unique Features for Antibody Engineering Applications
- Cancer-associated loss-of-function mutations in KCNQ1 enhance Wnt/β-catenin signalling disrupting epithelial homeostasis
- Investigating the Dynamics of the KCNN4 Channel: From the Determination of the Complete K+ Permeation Pathway Across the Channel to Its Opening by PIP2
- The key role of the dynamics and flexibility of proteins in functional mechanisms: How computational methods can contribute to their identification
Links
- ORCID https://orcid.org/0000-0002-5871-2372
- Google Scholar https://scholar.google.com/citations?user=YGq1xxYAAAAJ&hl=en
- Scopus https://www.scopus.com/authid/detail.uri?authorId=6603446410