Clelia Akiko Hiruma-Lima
Department of General and Applied Biology · Universidade Estadual Paulista Julio de Mesquita Filho
Biography
Clelia Akiko Hiruma-Lima is a full professor at the Department of Structural and Functional Biology (Physiology) at the Bioscience Institute of the São Paulo State University - UNESP (Botucatu, São Paulo, Brazil). Her work has been mainly focused on understanding the action of natural products (flavonoids and essential oil) in the treatment of gastrointestinal diseases (gastroesophageal reflux, peptic ulcers, intestinal inflammation and obesity). The morphofunctional, biochemical, and molecular aspects of gastrointestinal disorders are analyzed in rodents (mice and rats). The focus of the studies also involves the ethnopharmacological evaluation of Brazilian medicinal plants and all their therapeutic potential.
Education
Clelia Akiko Hiruma-Lima is a biologist from the State University of São Paulo (UNESP), holds a Master's degree in Pharmacology and Chemistry of Natural Products from UFPB, and a PhD in Physiology from Unicamp.
Recent Scopus Publications
- Citral exerts a more pronounced antinociceptive effect in obese adult male C57BL/6J mice mediated through the CB2 receptor
- Citral impairs intestinal changes caused by ulcerative colitis through modulation of antioxidant, anti-inflammatory and healing activities
- The Anthocyanidins Malvidin and Cyanidin Alleviate Irinotecan-Triggered Intestinal Mucositis by Modulating Oxidative Stress and Cytokine Release
- Maternal protein restriction impairs intestinal morphophysiology and antioxidant system in young male offspring rats
- Citral protects against metabolic endotoxemia, and systemic disorders caused by high-fat diet-induced obesity via intestinal modulation
Links
- ORCID https://orcid.org/0000-0002-8645-3777
- Google Scholar https://scholar.google.com/citations?user=jHcPFTwAAAAJ
- Scopus https://www.scopus.com/authid/detail.uri?authorId=6603682837