Maurizio Simmaco
Department of Neurosciences, Mental Health and Sensory Organs · Sapienza University of Roma
Research Interests
- Primary structure of antioxidant proteins. - Bioactive peptides peptides with pharmacological or antibacterial activities from amphibian skin: structure, activity and identification of post-translational modifications in bioactive peptides. - Phytotoxic lipo...
Biography
Maurizio Simmaco graduated in Medicine and Surgery in 1984, since 1989 he is specialist in Laboratory Medicine. Since 1994 he is full professor of Biochemistry and Molecular Biology. He teaches at the Faculty of Medicine and Psychology of the Sapienza University of Rome. He is Director of the Clinical Biochemical Analysis Laboratory Unit of the Sant'Andrea University Hospital in Rome. He is a member of the scientific bord of the European Society of Pharmacogenomics and Personalized Therapy (ESPT). Scientific Activities: - Primary structure of antioxidant proteins. - Bioactive peptides with pharmacological and/or antibacterial activities from amphibian skin: structure, activity and identification of post-translational modifications in bioactive peptides. - Phytotoxic lipodepsipeptides from Pseudomonas syringae. - Proteomic studies on T lymphocytes (2DE/MALDI-ToF mass spectrometry) as biosensors. - Pharmacogenomics and metabolomics.
Education
Academic career: 2003-present Full professor of Molecular Biology, Faculty of Medicine and Psychology, Sapienza University of Rome 2000-2003 Full professor of Biochemistry, II Faculty of Medicine, Sapienza University of Rome 1998-2000 Director of the Specialty School in Laboratory Medicine, University of Chieti 1994-2000 Full professor of Biochemistry, Faculty of Medicine, University of Chieti, Italy 1988-1994 Researcher at the National Research Council, Center of Molecular Biology Hospital career: 2003-2017 Director of the Advanced Molecular Diagnosis Unit (DiMA), Sant'Andrea Hospital, Sapien...
Recent Scopus Publications
- Investigating DRD2 and HTR2A polymorphisms in treatment-resistant schizophrenia: a comparative analysis with other treatment-resistant mental disorders and the healthy state
- The Impact of Concordance between Liquid and Tissue Biopsy for Actionable Mutations: Insights from the ROME Trial
- Genomically matched therapy in advanced solid tumors: the randomized phase 2 ROME trial
- The Potential Influence of Associated Antidepressants on the Pharmacokinetic Profile of Esketamine in Patients Affected by Treatment-resistant Depression
- Esketamine Combined With SSRI or SNRI for Treatment-Resistant Depression
Links
- ORCID https://orcid.org/0000-0003-4164-1472
- Scopus https://www.scopus.com/authid/detail.uri?authorId=7004605339