Francesca Cianci
Postdoctoral research fellow, Department of Biosciences · Università degli studi di Milano
Biography
I am currently a Postdoctoral research fellow in University of Milan, where I am the leader of several research projects. In March 2022, I have obtained my PhD in Molecular and Cellular biology in Milan. My enthusiasm for pursuing a career in research and development arise from my work in University. In my PhD, I have designed new therapeutic strategies to contrast the development and progression of several tumors, as Glioblastoma and Colorectal cancer.
Education
March 2022: Ph.D. in Molecular and Cellular Biology. Code: R-11 (English Course), Università degli studi di Milano. Milano, Italy. Thesis: Transmembrane Chloride Intracellular Channel 1 (tmCLIC1) is key regulator of CRCs’ metastasis February 2018: Master’s degree in Molecular Biology of the Cell. F9Y, LM-6- Biology class (English Course), Università degli studi di Milano. Milano, Italy Thesis: A possible role of CLIC1 protein as pharmacological target in solid tumors stem cells. February 2015: Bachelor’s degree in Scienze Biologiche. L13- Biology class, Università degli studi di Urbin...
Recent Scopus Publications
- An oncostatin M receptor and chloride intracellular channel 1 crosstalk drives key oncogenic pathways in glioblastoma
- Correction: Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells (Journal of Experimental & Clinical Cancer Research, (2025), 44, 1, (312), 10.1186/s13046-025-03577-3)
- Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells
- Correction to: Human antimicrobial peptide LL-37 contributes to Alzheimer’s disease progression (Molecular Psychiatry, (2022), 27, 11, (4790-4799), 10.1038/s41380-022-01790-6)
- Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives
Links
- ORCID https://orcid.org/0000-0002-9935-1526
- Scopus https://www.scopus.com/authid/detail.uri?authorId=57215092187