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Mauro Maccarrone

Professor and Chair, Department of Biotechnological and Applied Clinical Sciences · Università degli Studi dell'Aquila

https://researchid.co/k-5398-2012
@univaq.it
590Scopus Publications

Research Interests

Bioactive lipids Endocannabinoids Proresolving lipid mediators Signal transduction

Biography

Is Professor and Chair of Biochemistry at the Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila (Italy). He is also Head of the Lipid Neurochemistry Unit at the European Center for Brain Research – IRCCS Santa Lucia Foundation, Rome. For his research activity he has received the “4th Royan International Research Award for Reproductive Biomedicine” (2003), the “2007 IACM (International Association for Cannabis as Medicine) Award for Basic Research”, the “2016 Mechoulam Award”, the “2020 Tu Youyou Award”, and the “2020 International Space Station Research and Development Award” by the American Astronautical Society with NASA and CASIS. Chair of the 2015 Gordon Research Conference on “Cannabinoid Function in the CNS”. Visiting Professor at Leiden University (Leiden Institute of Chemistry, The Netherlands) in 2017, and at University of Cambridge (Department of Psychology, U.K.) in 2019.

Education

University of L’Aquila (I) M.S. in Biological Sciences (Biochemistry) - 1986 Universities of L’Aquila (I), of Chieti (I) and of Rome Tor Vergata (I) Ph.D. in Enzymology Applied to Medical Sciences - 1990 University of Utrecht (NL) Ph.D. in Bio-Organic Chemistry - 1992

Recent Scopus Publications

  1. Targeting GPR18: Structural modelling, ligand discovery, and therapeutic potential in neuroinflammatory disorders
    Biochemical Pharmacology, 2026
  2. Bone inflammation in postmenopausal women with type 2 diabetes or obesity in relation to Wnt signaling and bone strength
    Metabolism Clinical and Experimental, 2026
  3. Unraveling Endocannabinoid Signaling Pathways in Cisplatin-Induced Ototoxicity
    FASEB Journal, 2026
  4. Sustained Palmitoylethanolamide Infusion Restores Incentive Motivation and Synaptic Plasticity in the Tg2576 Mouse Model of Alzheimer’s Disease
    Cells, 2026
  5. FAAH Modulators from Natural Sources: A Collection of New Potential Drugs
    Cells, 2025

Research Outputs

Holder of the following granted patents: 1) Enol carbamate derivatives as modulators of fatty acid amide hydrolase (TW200948805, AR072346).

Grants / Consultancy

a. MoMa Project of the Italian Space Agency (ASI-ESA-NASA) 2006 – The endocannabinoid system in the induction of T cell apoptosis un-der microgravity conditions. Local PI.

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