Mazyar Yazdani
Department of Medical Biochemistry · Oslo University Hospital
Biography
Dr. Yazdani’s research journey began in toxicology, where he studied the mechanisms by which hazardous substances induce oxidative stress and developed in vitro (cell culture) models to examine these effects. His focus later shifted to exploring the role of oxidative stress in the pathophysiology of dry eye disease and potential treatments for corneal epithelial (limbal) stem cell deficiency. Currently, as a core member of the Metabolomics & Metabolic Molecular Biology group, he investigates the impact of metabolic changes on health and disease, with the goal of understanding disease mechanisms through mass spectrometry-based metabolomics. Additionally, he has maintained a strong interest in the biological role and effects of oxygen.
Education
2009-2014: PhD in Integrative Biology - Toxicology, University of Oslo, Norway Committee: Ketil Hylland , Ragnhild Paulsen & Tor Gjøen Collaborator: Gunnar Brunborg at the Norwegian Institute of Public Health Trial lecture: Mechanisms for endocrine disruption Thesis: In vitro, in ovo and in vivo models for cytotoxicity, oxidative stress, neurotoxicity and DNA damage ( Link )
Recent Scopus Publications
- Dry eye disease symptoms and associated risk factors in a Norwegian clinical cohort
- Iron Metabolism, Calcium, Magnesium and Trace Elements: A Review
- Schirmer Strips in Tear Metabolomics of Dry Eye Disease: Pre-analytical and Analytical Considerations
- Serum hepcidin concentration is lower in advanced stages of sporadic colorectal cancer
- Tear Global Metabolomic Differences in Pre-Operative Cataract Patients With and Without Dry Eye Disease
Links
- ORCID https://orcid.org/0000-0002-9187-3231
- Google Scholar https://scholar.google.com/citations?user=8GAtaWUAAAAJ
- Scopus https://www.scopus.com/authid/detail.uri?authorId=35118394600
- Personal Weblink https://www.ous-research.no/home/elgstoen/Group%20members/19836