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Iuliia Melnikova

Faculty of Pharmacy in Hradec Kralove, Department of Organic and Bioorganic Chemistry · Charles University, Faculty of Pharmacy in Hradec Kralove

https://researchid.co/melnikoi
@faf.cuni.cz
6Scopus Publications
91Google Scholar Citations
6Google Scholar h-index
4Google Scholar i10-index

Education

Saint-Petersburg State University of Industrial Technologies and Design: St. Petersburg, RU 2014-10-01 to 2018-09-30 | PhD in Organic Chemistry (Applied Chemistry and Ecology) St. Petersburg State Technological Institute (technical university) : St. Petersburg, RU 2009-09-01 to 2014-06-20 | Engineer (Chemical and Biotechnology)

Recent Scopus Publications

  1. Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection
    Nature Communications, 2025
  2. Exploring the effects of topoisomerase II inhibitor XK469 on anthracycline cardiotoxicity and DNA damage
    Toxicological Sciences, 2024
  3. The UHPLC-UV method applied for the forced degradation study of ixazomib and HRMS identification of its degradation products
    Journal of Pharmaceutical and Biomedical Analysis, 2023
  4. Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity
    Scientific Reports, 2021
  5. Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions
    Journal of Medicinal Chemistry, 2021

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