Reginaldo Brito dos Santos Junior
Laboratório de Patologia Estrutural e Molecular · Instituto Gonçalo Moniz - Fiocruz/BA
Research Interests
Cell adhesion Image Analysis
Biography
I am a biomedical scientist with experience in immunopathology, molecular pathology, and cell biology. I have investigated parasite–host interactions in Leishmania using confocal microscopy and immunofluorescence. I also study splenic disorganization and plasmacytosis in Visceral Leishmaniasis, specifically focusing on B-cell differentiation and plasmacytosis in both an experimental hamster model and human samples. Additionally, I have participated in COVID-19 immunopathology research. Throughout my training, I have strengthened my expertise in immunohistochemistry, histological analysis, and transcriptomic data analysis.
Education
MSc in Human Pathology - Universidade Federal da Bahia (UFBA)
Recent Scopus Publications
- Lymphocyte loss and plasmacytosis are associated with IL-6- and TNF-producing cells in the spleens of fatal COVID-19 cases
- Leishmania amazonensis infection impairs VLA-4 clustering and adhesion complex assembly at the adhesion site of J774 cells
- COVID-19 beyond DAD: Persisting microcirculation thrombosis, hidden infections, and early pulmonary fibrosis as remaining challenges of the disease
- Anti-leishmania infantum antibody-producing plasma cells in the spleen in canine visceral leishmaniasis
- Splenic Transcriptional Responses in Severe Visceral Leishmaniasis: Impaired Leukocyte Chemotaxis and Cell Cycle Arrest
Grants / Consultancy
Doctorate productivity scholarship: Coordenação de Aperfeicoamento de Pessoal de Nível Superior – CAPES (2023-present) None
Links
- ORCID https://orcid.org/0000-0002-8177-4301
- Scopus https://www.scopus.com/authid/detail.uri?authorId=57348509000