Salvia Cely Cerqueira Carvalho

Verified @gmail.com

Programa de Pós Graduação em Ciências da Saúde
Universidade Federal de Sergipe



        

https://researchid.co/salvia.cely

Farmacêutica formada pela Universidade Tiradentes (Unit). Mestra em Biotecnologia Industrial pela Universidade Tiradentes (PBI/Unit). doutoranda em Ciências da Saúde pela Universidade Federal de Sergipe (PPGCS/UFS). Possui habilitação e certificação em Serviços de Vacinação por Farmacêuticos pelo Conselho Federal de Farmácia (CFF). Enquanto aluna do Doutorado em Ciências da Saúde (PPGCS/UFS) trabalha na área de doenças epidemiológicas com foco na aplicabilidade de testes diagnósticos para detecção de hanseníase.

EDUCATION

Farmacêutica formada pela Universidade Tiradentes, mestre em Biotecnologia Industrial também pela Universidade Tiradentes (Unit) e doutoranda em Ciências em Saúde no Programa de Pós Graduação em Ciências da Saúde (PPGCS) na Universidade Federal de Sergipe (UFS).

RESEARCH, TEACHING, or OTHER INTERESTS

Medicine, Immunology and Microbiology, Biotechnology, Pharmacy

FUTURE PROJECTS

USO DOS BIOMARCADORES ANTI-PGL-I E AG85B COMO FERRAMENTA DIAGNÓSTICA DA HANSENÍASE

O diagnóstico da hanseníase ainda é um grande desafio para os serviços de saúde devido ao espectro imunológico da doença que dificulta o desenvolvimento de testes com biomarcadores no local de atendimento. Nas últimas décadas, muitos testes potenciais de biomarcadores surgiram como candidatos ao diagnóstico de hanseníase, mas nenhum deles mostrou precisão suficiente, especialmente para contatos com pessoas infectadas. Este estudo tem como objetivo avaliar o desempenho diagnóstico dos biomarcadores IgM Anti-PGL-I (Bioclin fast ML Flow) e Ag85B (ELISA e magnetoimunoensaio) como potencial ferramenta para diagnóstico de hanseníase. Trata-se de um estudo transversal de casos presumidos de hanseníase atendidos no Laboratório Central de Saúde Pública de Sergipe (LACEN/SE). Serão incluídos adultos presuntivos (≥18 anos) encaminhados para avaliação diagnóstica de hanseníase.


Applications Invited
Hanseníase, Mycobacterium leprae, Biomarcadores, Anti PGL-I, Antígeno 85B
3

Scopus Publications

Scopus Publications

  • Temporal and spatial trends of accidents with venomous animal in Brazil before and during the COVID-19 pandemic: a population-based ecological study
    Thayane Santos Siqueira, Lívia Silveira Silva, Jamile Rodrigues Cosme de Holanda, Sálvia Cely Cerqueira Carvalho, Adriano José dos Santos, Alexrangel Henrique Cruz Santos, José Rodrigo Santos Silva, and Victor Santana Santos
    FapUNIFESP (SciELO)
    ABSTRACT Objective: The objective of this study was to analyze the temporal and spatial trends of accidents involving venomous animals in Brazil during the pre- and COVID-19 pandemic periods. Methods: We conducted a population-based ecological study using comprehensive data from the Notifiable Diseases Information System, covering all accidents involving venomous animals in Brazil from January 2013 to December 2022. We did a temporospatial analysis to compare the incidence rates of accidents involving venomous animals per Brazilian municipality in the pre-pandemic period (January 2013 to February 2020) and the pandemic period (March 2020 to December 2022). To analyze the trend, the seasonal-trend model was used based on the classic additive decomposition model. For spatial distribution analysis, the Global Moran’s Index was used. Results: A total of 2,202,842 cases of accidents involving venomous animals were recorded. Brazil showed an increasing trend from 2017 to 2019 (annual percentage change [APC]: 0.98, p<0.001) and a stable trend from 2020 to 2022 (APC: 0.42, p<0.080). The North (APC: 0.19, p<0.330), South (APC: 0.04, p<0.953), and Southeast (APC: 0.26, p<0.312) regions presented a stable trend from 2020 to 2022. Spatial dependence of smoothed rates was observed in both the pre-pandemic (Moran’s I: 0.47; p=0.000) and COVID-19 pandemic periods (Moran’s I: 0.50; p=0.000). Conclusion: There was a stable trend in accidents involving venomous animals from 2020 to 2022 in Brazil. The spatial distribution of cases was heterogeneous for both periods studied.

  • Determinants of Delayed Leprosy Diagnosis in an Endemic Area of Northeast Brazil: A Cross-Sectional Study
    William Lucas da Silva Mendes Pina, Lorena Ferreira de Azevedo Melo, Héllen Néo da Rocha, Juliana de Moura, Leonardo Lopes-Luz, Lívia Silveira Silva, Sálvia Cely Cerqueira Carvalho, Glicya Monaly Claudino dos Santos, and Victor Santana Santos
    FapUNIFESP (SciELO)
    ABSTRACT Background: Delayed diagnosis remains a primary challenge in leprosy control, often resulting in severe physical impairment and significant psychological distress among those affected. The factors contributing to this delay are complex and multifactorial, encompassing both patient-related and healthcare system-related elements. To investigate the patient- and health system-related factors contributing to delayed diagnosis of leprosy in an endemic area of Northeast Brazil. Methods: This cross-sectional study included 247 leprosy patients. Demographic and clinical characteristics, along with data on patient- and health system-related determinants associated with delays in diagnosis, were collected. Univariate and multivariate Poisson regression analyses were performed to examine associations between the outcome (delay in months) and the independent variables. Results: The median time from the first healthcare visit to leprosy diagnosis was 15.0 months (interquartile range: 6.0-36.0). Approximately 17% of participants had grade 2 disability (G2D) at diagnosis. In the multivariate Poisson regression analysis, female sex, residence in rural areas, delayed healthcare seeking after symptom onset, lack of initial suspicion of leprosy, multiple referrals requiring four or more consultations before diagnostic confirmation, and prior misdiagnosis with treatment for another condition were independently associated with prolonged diagnostic delay. Conclusion: This study identified significant delays in leprosy diagnosis in Sergipe, Brazil, which may contribute to the persistently high proportion of new cases with G2D. Both patient- and health system-related factors were associated with longer diagnostic delays. Urgent interventions are warranted to increase disease awareness among the general population and strengthen the capacity of primary healthcare services.

  • Spatial clustering of dengue cases during the 2024 epidemic in Brazil
    Thayane Santos Siqueira, Lívia Silveira Silva, Jamile Rodrigues Cosme de Holanda, Sálvia Cely Cerqueira Carvalho, José Rodrigo Santos Silva, and Victor Santana Santos
    Oxford University Press (OUP)
    This study on the 2024 dengue epidemic in Brazil analysed 3.5 million cases. High-risk areas were identified in the Southeast and South regions. Spatial clustering and healthcare disparities were examined, showing a negative correlation between dengue incidence and healthcare coverage. Effective public health interventions are recommended.