SILVIA RODRIGUEZ SANCHEZ

"POST OPERATIVE RECURRENCE OF CROHN’S DISEASE AFTER COLONIC RESECTION: RESULTS FROM THE RESECOL STUDY BY GETECCU

INTRODUCTION Post operative recurrence (POR) of Crohn’s Disease (CD) after ileocecal resection (ICR) is well defined, but POR after colectomy is scarcely described. AIMS & METHODS: Multicenter, nationwide, retrospective study of CD patients who underwent segmental colectomy (SC) or subtotal colectomy (STC) between 2012 and 2023. Primary endpoint was clinical POR, defined as CD-related symptoms requiring salvage therapy beyond POR prophylaxis. Secondary endpoints included endoscopic POR, defined as CD-associated lesions at the anastomosis; association between clinical and endoscopic POR; comparison of clinical and endoscopic POR-free survival between types of colectomy; surgical recurrence (i.e., need for reoperation) between colectomy subtypes; and identification of factors associated with post-colectomy POR. RESULTS: 224 patients were included: 157 (70.1%) underwent SC and 67 (29.9%) underwent STC. In the SC group, patients were older (44.1 (SD 15.2) vs 39.2 (SD 14.2) years old,