virendra Chandrasekhar patil
Verified email at rediffmail.com
Medicine
Kims deemed to be University Karad
EDUCATION
MD medicine
RESEARCH INTERESTS
Medicine
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Iranian Heart Journal, ISSN: 17357306, Pages: 74-83, Published: Winter 2021
Caspian Journal of Internal Medicine, ISSN: 20086164, eISSN: 20086172, Pages: 223-227, Published: 2021
AniketBhaskar Avhad and VirendraChandrashekhar Patil
Journal of Medical Sciences (Taiwan), ISSN: 10114564, Pages: 76-85, Published: January-March 2021
Medknow
Background: Diabetes is an important risk factor of cardiomyopathy which can eventually lead to acute or chronic heart failure. Many factors such as obesity, hyperglycemia, suboptimal glycemic control, and hyperlipidemia predispose as well as aggravate long-term complications in diabetes mellitus (DM). Aim: The present study was conducted to assess the relation of glycosylated hemoglobin (HbA1c) and obesity indices (body mass index [BMI], waist circumference [WC]) with diastolic dysfunction in participants with type 2 DM (T2DM). Methods: This was a cross-sectional study conducted at the teaching hospital during a 1-year period. All 100 consecutive T2DM participants were investigated for HbA1c, blood sugars and lipid profile parameters, and echocardiography. Standardized transthoracic echocardiographic examination was performed (American Society of Echocardiography) using Vivid S6 ultrasound machine with 4–5 MHz probe. Left ventricular diastolic dysfunction (LVDD) was labeled if 3 or more of these variables were abnormal: “Septal e <7 cm/s, lateral e <10 cm/s, E/e' >14, LA volume index >34 mL/m2, and Peak TR velocity >2.8 m/s.” Results: Out of the total 100 diabetics, 37% had diastolic dysfunction (Grade I: 30 [81.08%] and Grade II: 7 [18.91%]). The peak early transmitral filling wave velocity (E) in diabetics with obesity was low as compared to diabetics with normal weight (44 ± 11 cm/s vs. 52 ± 7.5 cm/s). Higher BMI was associated with higher peak late transmitral velocity (A) (61 ± 14 cm/s vs. 38 ± 6.24 cm/s). The mean of E/A ratio was significantly lower in diabetics with obesity. The E/e' ratio was higher in diabetics with obesity (14.8 ± 2.8 vs. 12.86 ± 2.14). The mean of WC was 90.18 ± 6.82 cm in participants of diastolic dysfunction, whereas it was 86.46 ± 6.42 cm in those without dysfunction. Diastolic dysfunction was present in participants with a suboptimal glycemic control, HbA1c ≥ 6.% (40%), with longer duration of diabetes (62.16%) (P = 0.003). Thus, a higher BMI was associated with higher diastolic dysfunction (P = 0.027). Conclusions: The present study reveals burden of LVDD in asymptomatic T2DM participants with its significant association with age, obesity indices (WC and BMI), HbA1c levels, and longer duration of diabetes. This highlights the magnitude of obesity and suboptimal glycemic control that should be considered in the management of cardiac complications in the form of development of diastolic dysfunction. It will benefit in triage for the optimal management of diabetes.
VirendraChandrashekhar Patil, HarshaVirendra Patil, and ShivajiT Mohite
Journal of Natural Science, Biology and Medicine, ISSN: 09769668, eISSN: 22297707, Pages: 64-74, Published: January-June 2021
Medknow
Background: Acinetobacter, a nonfermenting Gram-negative coccobacilli, have emerged as significant pathogens causing multidrug-resistant (MDR) ventilator-associated pneumonia (VAP). Metallo-beta-lactamase (MBL)-producing Acinetobacter spp. have become an emerging therapeutic concern worldwide due to the MDR isolates. Aim and Objectives: Phenotypic detection of MBL producing MDR Acinetobacter isolates in patients with VAP and to study the antibiotic susceptibility pattern of MBL-producing isolates. Materials and Methods: This was a prospective observational and noninterventional study conducted on patients with VAP over a period of 2 years. This study was conducted at a tertiary care teaching hospital in the intensive care unit. A total of 164 MBL-producing MDR AB isolates were included in the study. MBL was detected by imipenem-EDTA double-disc synergy test (DDST), imipenem-EDTA combined disc synergy test (CDST-IPM), and MBL-E test. Results: A total of 188 samples were enrolled for the study, fulfilling the inclusion criteria of VAP. Total MDR Acinetobacter spp. isolates were 188 (76.42%) of them, 164 (87.23%) were MBL producing and 24 (12.76%) were nonMBL (P < 0.002). Total 11.17% and 88.83% MDR VAP due to Acinetobacter spp. were early-onset VAP and Late-onset VAP, respectively (P < 0.001). Late-onset VAP due to MDR Acinetobacter spp. was predominant in the present study caused by Acinetobacter spp. Of total 188 MDR Acinetobacter isolates, 156 (82.98%) were Acinetobacter baumannii, 15 (7.98%) were Acinetobacter iwoffii, 9 (4.79%) were Acinetobacter calcoacetiucs, 5 (2.66%) were Acinetobacter hemotyticus, and 3 (1.59%) were ABC complex, predominated by A. baumannii (P < 0.001). Of total 188 MDR Acinetobacter spp. 164 (87.23%) were putative MBL producing and 24 (12.67%) were nonMBL Acinetobacter spp. Of 164 MBL-producing isolates, 141 (85.98%) were detected by the DDST method, and 23 (14.02%) were DDST negative. Total 146 (89.02%) MDR Acinetobacter spp. were detected by a combined disc test-IMP test. A total of 152 (92%) MDR Acinetobacter spp. were detected by MBLe-Test. All MBL-producing MDR Acinetobacter spp. isolates (164) were resistant to piperacillin (PI), piperacillin + tazobactam (PIT), ciprofloxacin (CIP), ceftazidime (CAZ), cefepime (CPM), imipenem (IMP), and meropenem (MRP). The tigecycline (21.34%) resistance was significantly less compared to all other antibiotics. Conclusions: The present study highlighted the burden of MDR MBL producing Acinetobacter spp. in patients with VAP. About three-fourth of patients with VAP had MDR Acinetobacter spp. Eighty percent were MDR Acinetobacter spp. were MBL producers. MDR Acinetobacter isolates, including MBL producer, were significantly higher in late-onset VAP. The ability of phenotypic identification of Acinetobacter spp. for MBL producer among imipenem-EDTA double-disc synergy test (DDST), CDST-IPM and MBL-E Test were comparable. All MBL-producing MDR Acinetobacter spp. isolates were resistant to PI, Ciprofloxacin, CAZ, CPM, IMP, and MRP. The tigecycline resistance was significantly less (1/5th). The study of antibiotic sensitivity patterns and screening for MBL production among A. baumannii isolates is essential for controlling Acinetobacter infections. The judicious use of antimicrobial therapy and combined approaches of rotational antibiotic therapy is strongly suggested.
Purushottam Narayandas Toshniwal and Virendra C Patil
International Journal of Research in Pharmaceutical Sciences, eISSN: 09757538, Pages: 4032-4038, Published: 9 July 2020
GP Innovations Pvt. Ltd.
The present observational study was conducted to evaluate the cardiological manifestations in chronic alcoholic in relation with Electrocardiographic and 2-Dimensional Transthoracic Echocardiogram and Doppler findings. In Present study we observed most common 2-D echocardiographic finding being Grade 1 Diastolic Dysfunction (i.e. 28.35%), followed by Left ventricular Dysfunction (i.e.7.87%) being second most common finding, followed by mild Pulmonary Hypertension (i.e. 5.51%). In present study, the observed most common Electrocardiographic finding being sinus rhythm ( i.e. 34.6%) followed by second most common finding being atrial fibrillation (i.e. 13.38%) followed by sinus tachycardia ( i.e. 11.18%) so most common abnormal elctro-cardiographic finding is Atrial fibrillation. The present study was crosssectional, descriptive, hospital based observational study to assess cardiac function in chronic alcoholic by use of Electrocardiogram and Two Dimensional Transthoracic Echocardiogram and Doppler function. Duration of Study is 18 months and Study Setting is conducted in patients admitted in wards and ICU under Department of Medicine, Krishna Hospital and Medical Research Centre, Karad. There is Study Population is all alcoholic patients admitted in wards and ICU during the period from October 2016 to March 2018 under Department of Medicine, Krishna Hospital and Medical Research Centre Karad with alcohol consumption duration more than 5 years.
International Journal of Pharmaceutical Research, eISSN: 09752366, Pages: 2820-2825, Published: July-September 2020
SynthesisHub Advance Scientific Research
International Journal of Pharmaceutical Research, eISSN: 09752366, Pages: 2795-2800, Published: July-September 2020
SynthesisHub Advance Scientific Research
International Journal of Pharmaceutical Research, eISSN: 09752366, Pages: 2750-2755, Published: July-September 2020
SynthesisHub Advance Scientific Research
Journal of Natural Science, Biology and Medicine, ISSN: 09769668, eISSN: 22297707, Pages: 93-99, Published: July-December 2020
Journal of Krishna Institute of Medical Sciences University, ISSN: 22314261, Pages: 50-66, Published: April-June 2020
International Journal of Advanced Science and Technology, ISSN: 20054238, eISSN: 22076360, Issue: 5 Special Issue, Pages: 1188-1200, Published: 28 March 2020
Pravara Medical Review, ISSN: 09750533, eISSN: 09760164, Pages: 23-29, Published: 1 March 2020
European Journal of Molecular and Clinical Medicine, eISSN: 25158260, Pages: 74-79, Published: 2020
SynthesisHub Advance Scientific Research
Journal of Cardiovascular Disease Research, ISSN: 09753583, eISSN: 09762833, Pages: 56-59, Published: 2020
Journal of Critical Reviews, eISSN: 23945125, Pages: 481-485, Published: 2020
SynthesisHub Advance Scientific Research
Journal of Critical Reviews, eISSN: 23945125, Pages: 981-986, Published: 2020
SynthesisHub Advance Scientific Research
VirendraC Patil, AniketB Avhad, AkshayR Kulkarni, and KaustubhA Pandere
Journal of Natural Science, Biology and Medicine, ISSN: 09769668, eISSN: 22297707, Pages: 39-44, Published: January-June 2020
Medknow
International Journal of Advanced Science and Technology, ISSN: 20054238, eISSN: 22076360, Pages: 1254-1264, Published: 2020
Journal of Datta Meghe Institute of Medical Sciences University, ISSN: 09743901, eISSN: 22501231, Pages: 383-390, Published: October-December 2019
Journal of Krishna Institute of Medical Sciences University, ISSN: 22314261, Pages: 53-62, Published: April-June 2019
Journal of Krishna Institute of Medical Sciences University, ISSN: 22314261, Pages: 53-62, Published: April-June 2019
Journal of Krishna Institute of Medical Sciences University, ISSN: 22314261, Pages: 1-18, Published: 2019
Journal of Krishna Institute of Medical Sciences University, ISSN: 22314261, Pages: 90-94, Published: 2019
Vijaya S Rajmane, Shivkumar T Rajmane, Virendra C Patil, and Vinayak V Raje
Archives of Clinical Infectious Diseases, ISSN: 23452641, eISSN: 20081081, Published: January 2018
Kowsar Medical Institute
Virendra C. Patil, Harsha V. Patil, Amardip Rajput, Shruti S Rao, and Jayesh N Shetye
Journal of Cardiovascular Disease Research, ISSN: 09753583, eISSN: 09762833, Pages: 6-15, Published: 1 January 2017
SynthesisHub Advance Scientific Research
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