wassanm.husein

Verified @gmail.com

physiology
Medical College, Ibn Sina University of Medical and Pharmaceutical Sciences, Baghdad, Iraq



              

https://researchid.co/w203040

RESEARCH, TEACHING, or OTHER INTERESTS

Physiology, Animal Science and Zoology, General Biochemistry, Genetics and Molecular Biology, Biochemistry

5

Scopus Publications

54

Scholar Citations

4

Scholar h-index

1

Scholar i10-index

Scopus Publications


  • Ameliorative Effect of Alpha Lipoic Acid on Manganese-Induced Testicular Dysfunction
    Wassan Mhammed Husain, Raghad Raad Hwidyii, and Ali Mosa Rashid Al-Yasari

    ResearchersLinks Ltd

  • Protective effects of allicin against stanozolol-induced cardiotoxicity: Physiological and histopathological evidence in a rabbit model
    Mohammed Hayder Asker, Noor AL‐Huda Salah AL‐Zuhairy, Wassan Mhammed Husain, and Mustafa Riyadh Abdullah

    Wiley
    AbstractBackgroundThere are many forms of anabolic steroids, including stanozolol (Winstrol), which are popular for their muscle‐building effects but dangerous to the heart. This present work is aimed at evaluating the pharmacologica impact of allicin, a natural attribute obtained from garlic, on obstructing cardiac injury in rabbits that received stanozolol.MethodsThirty rabbits were divided into three groups: control, stanozolol‐treated, and stanozolol plus allicin. Cardiac function was assessed by measuring troponin, creatine kinase (CK), Galectin‐3, and GDF‐15. Oxidative stress and antioxidant markers, including malondialdehyde (MDA), glutathione, and catalase, were analyzed. Inflammatory mediators such as C‐reactive protein (CRP), interleukin‐6 (IL‐6), NF‐κB, iNOS, nitric oxide (NO), tumor necrosis factor‐alpha (TNF‐α), and interleukin‐1 beta (IL‐1β) were evaluated. Lipid profile parameters, including total cholesterol, low‐density lipoprotein (LDL), and high‐density lipoprotein (HDL), were measured. Histopathological examination assessed myocardial damage, fibrosis, and collagen deposition.ResultsStanozolol administration significantly increased cardiac damage markers, oxidative stress, and inflammatory mediators while causing dyslipidemia, characterized by elevated LDL and total cholesterol and reduced HDL. Allicin co‐administration effectively countered these effects by reducing oxidative stress and inflammation, restoring antioxidant balance, and improving lipid profiles. Histopathological analysis revealed severe myocardial disorganization, necrosis, and fibrosis in the stanozolol group, whereas the allicin‐treated group exhibited preserved myocardial structure with reduced collagen deposition.ConclusionAllicin significantly mitigates stanozolol‐induced cardiotoxicity by reducing oxidative stress, inflammation, lipid dysregulation, and myocardial damage, as evidenced by biochemical and histopathological findings. These results suggest that allicin may serve as a potential therapeutic agent to counteract the cardiovascular risks associated with anabolic steroid use.


  • Effect of different doses from ZnONPS on the pituitary-testes axis function in adult male rats
    Wassan Mhammed Husain, Jawad Kadhim Araak, and Orooba Mohammed Saeed Ibrahim

    ResearchersLinks Ltd
    | In our study, ZnONPs was prepared and characterized for investigation of pituitary-testes axis function in adult male rats. Fifty healthy adult male rats selected, weighted 300 ± 50 gm, randomly divided to five group each group have ten animals. One of them group consider as control group and other four group designed as (G1, G2, G3 and G4) group which receive oral dose of ZnONPs in different concentration (5, 10, 20 and 40 mg/kgB.W) respectively for 56 day. Blood samples were collected via cardiac puncture for serum collection in (zero time, 28 and 56 day of experiment). The results showed significant (P<0.05) elevation of testosterone and FSH hormones concentration in G3 and G4 after 56 day of experimental period as a compared with zero time and 28 day of experiment, whereas LH and inhibin B hormones concentration showed a significant (P<0.05) decrement in all group at 56 day as a compared with control group and other period time. Histological study of testes and pituitary gland showed different pathological changes on these two gland’s tissue and cells as mild to severe effects especially at dose (20 and 40 mg/kg B.W). Histometric study of seminiferous tubules illustrated a significant (P<0.05) elevation of seminiferous tubules diameters in G4 group, whereas showed non-significant (P˃0.05) differences in number of interstitial cells in treated groups.

RECENT SCHOLAR PUBLICATIONS

  • Ameliorative Effect of Alpha Lipoic Acid on Manganese-Induced Testicular Dysfunction
    WMHRRHAMR Al-Yasari3
    Pakistan J. Zool 57 (2), 887-894 2025

  • Evaluating the efficacy of berberine supplement versus ozempic injection in modulating glycemic state, lipid metabolism and body weight in streptozotocin-induced diabetic rats
    WM Husain, IJ Mohammad, DN Al-Saidi
    Adv. Anim. Vet. Sci 13 (3), 704-711 2025

  • Assessment Of Hematological Parameters In Rabbits Treated With Ivermectin
    NALHSZWMHMMNKI Alzand
    African Journal of Biomedical Research 27 (3), 1926 2024

  • The correlation between iron storage marker (ferritin) and glycated hemoglobin in patient with type two diabetes mellitus
    WM Husain, RE Ahmed
    Journal of Genetic and Environmental Resources Conservation 10 (2), 158-162 2022

  • The Correlation between Magnesium and HbA1C in type Two Diabetes
    WM Husain, RE Ahmed
    International Journal of Science and Management Studies (IJSMS) 5 (4), 97-82 2022

  • Metformin's hypolipidemic action in obese rats and its influence on leptin hormone levels
    ZS Ali, WM Husain
    Journal of Genetic and Environment Conservation 10 (1), 67-74 2022

  • The Effective Role of Phitofert Supplement in Male Reproductive Hormones and Epididymal Sperm Quality in Carbon Tetrachloride (CCL4) Treated Rats
    ZSA Wassan Mhammed Husain1 *
    Advances in Animal and Veterinary Sciences 10 (2), 292 2022

  • Study The Role of Nigella Sativa Silver Antiparticles on Some Liver Biomarkers and Hepatocyte Comet Assay in Stressed Rats
    WM Husain
    Annals of R.S.C.B. 25 (6), 2529-2543 2021

  • Green Synthesis of Zinc Oxide Nanoparticles from (Punica granatum L) Pomegranate Aqueous Peel Extract
    JKAOMSI Wassan Mhammed Husain
    The Iraqi Journal of Veterinary Medicine 43 (2), 6-14 2019

  • Effect of different doses from znonps on the pituitary-testes axis function in adult male rats
    AJK HusainWM, OMS Ibrahim
    Adv. Anim. Vet. Sci 7 (7), 550-556 2019

  • Evaluation of Zinc Oxide Nanoparticles Biosynthesized from Pomegranate (Punica granatum L.) Peel Extract on Pituitary – Testes Axis in Adult Male Rats
    WM Husain
    2019

  • Effect of zinc oxide nanoparticles on sperm cell comet assay, testis malondialdehyde and glutathione peroxidase levels in adult rats.
    OMSI Wassan M Husain, Jawad K Araak
    Online Journal of Veterinary Research 23 (3), 206-213 2019

  • Protective Role of Pomegranate peel extract on the Pituitary gland of adult male rabbits treated with CCL4
    JK Arrack, WM Hussen
    Journal of Kerbala for Agricultural Sciences 4 (5), 83-98 2017

  • Protective Role of Pomegranate Peel Extract on Testis in Adult Male Rabbits Treated with Carbon Tetrachloride
    WM Hussen, JK Arrack
    Iraqi J. Vet. Med 38 (1), 74-82 2014

  • the protective role of pomegranate peel extract (punica granatum l.) on the pituitary gland and testis function in local adult male rabbits exposed to carbon tetrachloride
    WM Husain
    College of Veterinary Medicine / University of Baghdad in Partial 2013

  • Study The Effect Of E-Cigarette Vaping On Hematological Parameters In Adult Male
    WM Husain


MOST CITED SCHOLAR PUBLICATIONS

  • Green Synthesis of Zinc Oxide Nanoparticles from (Punica granatum L) Pomegranate Aqueous Peel Extract
    JKAOMSI Wassan Mhammed Husain
    The Iraqi Journal of Veterinary Medicine 43 (2), 6-14 2019
    Citations: 22

  • Effect of different doses from znonps on the pituitary-testes axis function in adult male rats
    AJK HusainWM, OMS Ibrahim
    Adv. Anim. Vet. Sci 7 (7), 550-556 2019
    Citations: 9

  • Protective Role of Pomegranate Peel Extract on Testis in Adult Male Rabbits Treated with Carbon Tetrachloride
    WM Hussen, JK Arrack
    Iraqi J. Vet. Med 38 (1), 74-82 2014
    Citations: 9

  • Effect of zinc oxide nanoparticles on sperm cell comet assay, testis malondialdehyde and glutathione peroxidase levels in adult rats.
    OMSI Wassan M Husain, Jawad K Araak
    Online Journal of Veterinary Research 23 (3), 206-213 2019
    Citations: 5

  • The Effective Role of Phitofert Supplement in Male Reproductive Hormones and Epididymal Sperm Quality in Carbon Tetrachloride (CCL4) Treated Rats
    ZSA Wassan Mhammed Husain1 *
    Advances in Animal and Veterinary Sciences 10 (2), 292 2022
    Citations: 2

  • Evaluation of Zinc Oxide Nanoparticles Biosynthesized from Pomegranate (Punica granatum L.) Peel Extract on Pituitary – Testes Axis in Adult Male Rats
    WM Husain
    2019
    Citations: 2

  • The correlation between iron storage marker (ferritin) and glycated hemoglobin in patient with type two diabetes mellitus
    WM Husain, RE Ahmed
    Journal of Genetic and Environmental Resources Conservation 10 (2), 158-162 2022
    Citations: 1

  • The Correlation between Magnesium and HbA1C in type Two Diabetes
    WM Husain, RE Ahmed
    International Journal of Science and Management Studies (IJSMS) 5 (4), 97-82 2022
    Citations: 1

  • Metformin's hypolipidemic action in obese rats and its influence on leptin hormone levels
    ZS Ali, WM Husain
    Journal of Genetic and Environment Conservation 10 (1), 67-74 2022
    Citations: 1

  • Study The Role of Nigella Sativa Silver Antiparticles on Some Liver Biomarkers and Hepatocyte Comet Assay in Stressed Rats
    WM Husain
    Annals of R.S.C.B. 25 (6), 2529-2543 2021
    Citations: 1

  • Protective Role of Pomegranate peel extract on the Pituitary gland of adult male rabbits treated with CCL4
    JK Arrack, WM Hussen
    Journal of Kerbala for Agricultural Sciences 4 (5), 83-98 2017
    Citations: 1