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Scopus Publications
Scopus Publications
- A Retrospective comparative analysis of postoperative renal function modification following retrograde intrarenal surgery versus minimally invasive percutaneous nephrolithotomy (≤ 26Ch) using serum creatinine-based metrics
Luigi Candela, Pietro Scilipoti, Luca Villa, Eugenio Ventimiglia, Mariela Corrales, et al.
World Journal of Urology, 2026 - Cancer-specific mortality differences between radical prostatectomy and radiotherapy after biochemical recurrence: analysis of a health system-wide cohort
Carlo Silvani, Alfonso Santangelo, Alex Stephens, Jack Considine, Adam Msska, et al.
World Journal of Urology, 2026 - Diagnostic and treatment delays in penile cancer: a call to improve awareness and referral
Fausto Negri, Giuseppe Basile, Armando Galdieri, Mattia Longoni, Massimiliano Raffo, et al.
World Journal of Urology, 2026 - PD1-IL2v expands and induces effector CD8+ TILs, but not Tregs, in the BCG treated orthotopic non-muscle invasive bladder cancer model
Irene Locatelli, Marco Lorenzoni, Chiara Venegoni, Alessia Di Coste, Rita Sorrentino, et al.
Journal of Experimental and Clinical Cancer Research, 2026 - Active surveillance for renal masses up to 2 cm: long-term oncological outcomes from a prospective multi-institutional study
Chiara Re, Alessandro Bertini, Pietro Scilipoti, Tommaso Saccucci, Guglielmo Mantica, et al.
World Journal of Urology, 2026 - Distinct genomic, microenvironmental, and nephron signatures in VHL kidney cysts and tumors
Isaline Rowe, Francesca Corea, Giovanni B. Pipitone, Giulia M. Scotti, Roberta Lucianò, et al.
Scientific Reports, 2026 - Real-world outcomes of bladder-sparing strategies for BCG-unresponsive non-muscle-invasive bladder cancer: a multicenter study
Pietro Scilipoti, Paolo Zaurito, Mattia Longoni, Giovanni Tremolada, Andrea Cosenza, et al.
World Journal of Urology, 2026 - Development and validation of PEYRO-Q: a novel multidimensional patient-reported outcome measure for Peyronie’s disease
Andrea Cocci, Mattia Lo Re, Marta Pezzoli, Javier Romero-Otero, Juan Ignacio Martinez Salamanca, et al.
Sexual Medicine, 2026
Background Peyronie’s disease (PD) is a condition with significant physical, sexual, and psychological impact that is not fully captured by existing Patient-Reported Outcome (PRO) instruments. Aim To develop and preliminarily validate the PEYROnie’s disease Questionnaire (PEYRO-Q), a novel multidimensional PRO questionnaire designed to provide a comprehensive and inclusive assessment of PD. Methods A prospective multicenter study was conducted between April and July 2025, enrolling 206 adult patients with PD. The PEYRO-Q, developed in accordance with COSMIN guidelines, includes 10 domains and 12 items assessing deformity severity and stability, pain, penile shortening, sexual function, erectile function, psychological distress, and sexual avoidance. Content validity was established through expert panel review. Internal consistency was evaluated using Cronbach’s alpha, while test–retest reliability was assessed over a 2-week interval. Exploratory Factor Analysis (EFA) with promax rotation was performed to investigate the underlying structure. Outcomes Primary outcomes were internal consistency, test–retest reliability, and factor structure of the PEYRO-Q. Results The study population had a median age of 62 years, with most patients reporting moderate penile curvature and long-standing disease stability. The PEYRO-Q demonstrated excellent internal consistency (Cronbach’s α = 0.90) and test–retest reliability (α = 0.89–1.00; Intraclass Correlation Coefficient, ICC up to 0.99). EFA supported a three-factor structure explaining 62.2% of total variance, corresponding to clinical/functional burden, disease perception and evolution, and psychological/behavioral impact. Moderate correlations between domains (eg, erectile aid use and psychological distress, r = 0.41) confirmed related but distinct constructs. The questionnaire allowed detailed and inclusive profiling of sexual function and psychological burden. Clinical Implications The PEYRO-Q offers a practical, inclusive, and comprehensive tool for assessing PD burden in both clinical practice and research settings. Strengths & Limitations Strengths include the multidimensional and inclusive design, strong psychometric performance, and multicenter prospective validation. Limitations include the predominantly Italian cohort, lack of longitudinal responsiveness data, absence of direct comparison with existing instruments, and limited clinical characterization such as plaque localization. Conclusion The PEYRO-Q is a reliable and clinically relevant PRO instrument for PD, warranting further validation to confirm responsiveness and cross-cultural applicability. - Iatrogenic ureteric injuries after abdominal surgery: a systematic review and meta-regression from the European Association of Urology Endourology Section
Pietro Scilipoti, Nicola Nannola, Federico Zorzi, Carlos Gonzalez Gonzalez, Marie Chicaud, et al.
BJU International, 2026
Objective To systematically evaluate management strategies and associated outcomes of iatrogenic ureteric injuries, focusing on clinical success, renal unit loss, and the need for subsequent endoscopic or reconstructive procedures. Patients and Methods A pre‐registered protocol (CRD420251184018) guided a comprehensive search of PubMed and EMBASE databases. Observational studies reporting outcomes of ≥20 patients treated for iatrogenic ureteric injury with complete data on follow‐up were included. Risk of bias was assessed using Risk Of Bias In Non‐randomised Studies of Interventions (ROBINS‐I). Random‐effects meta‐analysis with PLOGIT transformation was applied, stratifying results by treatment type and timing. Meta‐regression examined the association of treatment modality with outcomes adjusting for the timing of reconstruction. Results A total of 30 studies were included (1517 patients), all retrospective and characterised by substantial heterogeneity in definitions and follow‐up practices. ROBINS‐I indicated serious risk of bias in most domains. The pooled clinical success rate was 87% (95% confidence interval [CI] 80–91%), with high heterogeneity I 2 = 76.0% due to different follow‐up protocols, success outcomes, type and timing of management. Studies dominated by reconstructive procedures (15 studies) had higher success (91%, 95% CI 84–95%), than those primarily using endoscopic techniques (six studies; 66%, 95% CI 58–73%). Renal unit loss occurred in 2.3% (95% CI 1.5–3.6%). No differences in loss of renal unit were found. Additional endoscopic interventions were required in 3% (95% CI 2–4%) and further reconstructive surgery in 5% (95% CI 3–9%). Meta‐regression showed endoscopic index management was associated with lower odds of success (odds ratio [OR] 0.14, 95% CI 0.05–0.40) and higher need for further reconstruction (OR 5.64, 95% CI 1.61–19.8). Conclusions Across retrospective and heterogeneous studies, reconstructive‐dominant management of iatrogenic ureteric injuries was associated with higher clinical success compared with endoscopic‐dominant approaches, while renal unit loss remained uncommon. Endoscopic management was feasible in selected cases but was more frequently followed by additional endoscopic or reconstructive interventions. - The impact of prostate size on single-port robot-assisted radical prostatectomy surgical outcomes
Alessio Finocchiaro, Muhannad Aljoulani, Mustafa Almajedi, Viganò Silvia, Alessandro Bertini, et al.
BJU International, 2026
Objective To evaluate the effect of prostate size on surgical outcomes in single‐port robot‐assisted radical prostatectomy (SP‐RARP). Patients and Methods We conducted a multicentre analysis of patients undergoing SP‐RARP between 2018 and 2024. Our primary endpoint was to assess the impact of prostate size on SP‐RARP surgical outcomes, including operating time, estimated blood loss (EBL), nerve‐sparing status, margin status, and intra‐/postoperative complications. Logistic regression models assessed the independent impact of prostate size (calculated at final pathology) on these outcomes. Results A total of 343 patients were included; the median (interquartile range) prostate size was 46 (37–52) g. Of these, 114 patients had a prostate size of ≤40 g, 175 of 41–69 g, and 54 of ≥70 g. Larger prostates were associated with significantly prolonged operating time (265 vs 301 vs 306 min, P 0.9) rates between prostate size groups. In multivariable logistic regression, prostate size remained an independent predictor of prolonged operating time above median ( P = 0.012), increased EBL above median ( P = 0.007), and lower nerve‐sparing ( P = 0.002). No significant association was found with margin status ( P = 0.092) or postoperative complications ( P > 0.9). Conclusions Prostate size impacts intraoperative complexity in SP‐RARP but does not increase complication or margin rates. These findings support the feasibility and safety of SP‐RARP across a broad range of prostate sizes, consistent with trends reported for multiport RARP. - Varicocele Treatment in Azoospermia Before Artificial Reproductive Techniques: Critical Considerations by the EAU Guidelines Panel on Sexual and Reproductive Health
Luca Boeri, Marij Dinkelman-Smit, Christian Fuglesang S. Jensen, Suks Minhas, Andrea Salonia
European Urology, 2026 - Guideline of guidelines: Peyronie's disease
Francesco Chierigo, Giuseppe Fallara, Marco Tozzi, Andrea Salonia, Matteo Ferro, et al.
BJU International, 2026 - Incarcerated Patients Present With More Advanced Bladder Cancer Stage: A Statewide Analysis
Carlo Silvani, Alfonso Santangelo, Jack Considine, Anna Tylecki, Shane Tinsley, et al.
Urology Practice, 2026 - Evolution and innovation in urethroplasty: a comprehensive narrative review of graft types and surgical techniques
Donato Cannoletta, Filippo Pederzoli, Christian Yepes, Pankaj Joshi, Andrea Salonia, et al.
International Journal of Impotence Research, 2026 - Area deprivation and cancer-specific mortality in non-muscle-invasive bladder cancer: a statewide analysis
Carlo Silvani, Alfonso Santangelo, Jack Considine, Anna Tylecki, Alex Stephens, et al.
BJU International, 2026 - Optimizing oncological outcomes in high-grade non-muscle invasive bladder cancer: The impact of a surgeon-led treatment pathway
Pietro Scilipoti, Giuseppe Rosiello, Alfonso Santangelo, Alessandro Viti, Mattia Longoni, et al.
Urologic Oncology Seminars and Original Investigations, 2026 - Re: Gautier Müllhaupt, Lukas Hechelhammer, Nicole Graf, et al. Prostatic Artery Embolisation Versus Transurethral Resection of the Prostate for Benign Prostatic Obstruction: 5-year Outcomes of a Randomised, Open-label, Noninferiority Trial. Eur Urol Focus 2024;10:788–95
Francesco Montorsi, Edoardo Pozzi, Marco Bianchi, Alberto Briganti, Paolo Capogrosso, et al.
European Urology Focus, 2026 - Efficacy and Safety of Checkpoint Inhibitors Combined with Bacillus Calmette-Guérin (BCG) in BCG-naïve High-risk Non–muscle-invasive Bladder Cancer: Synthesis of Evidence from the ALBAN, CREST, and POTOMAC Trials
Pietro Scilipoti, Paolo Zaurito, Mattia Longoni, Maurizio Colecchia, Francesco Montorsi, et al.
European Urology, 2026 - The educational level impact on treatment adherence in PDE5i-naïve men with erectile dysfunction: A real-life cross-sectional study
Gabriele Birolini, Alessandro Bertini, Edoardo Pozzi, Massimiliano Raffo, Fausto Negri, et al.
Andrology, 2026 - Are we ready to explore administration of botulinum toxin in the management of male sexual dysfunctions?
Simone Cilio, Margarida Henriques, Pedro Ramos, Georgios Tsampoukas, Marco Capece, et al.
Journal of Sexual Medicine, 2026 - Serum Antimüllerian Hormone as a Biomarker of Functional Testicular Reserve: A Comparative Analysis
Edoardo Pozzi, Fausto Negri, Massimiliano Raffo, Alessandro Bertini, Christian Corsini, et al.
Journal of Clinical Endocrinology and Metabolism, 2026 - Low testosterone in primary infertile men is associated with a history of maternal obesity during pregnancy: Findings from a cross-sectional study
Fausto Negri, Luca Boeri, Edoardo Pozzi, Massimiliano Raffo, Riccardo Ramadani, et al.
Andrology, 2026 - Association of Area Deprivation Index in Kidney Cancer Mortality
Silvia Viganò, Anna Tylecki, Alessandro Bertini, Alessio Finocchiaro, Banna Hussain, et al.
Urology Practice, 2026 - Prostate cancer: the phoenix of population screening. Evidence, controversies and organisational perspectives in the experience of the Lombardy Region
Epidemiologia E Prevenzione, 2026 - Laser Energy Application in Endoscopic Kidney-Sparing Surgery for Upper Tract Urothelial Carcinoma: A Systematic Review of Oncological Outcomes and Surgical Complications
Federico Zorzi, Pietro Scilipoti, Stefano Moretto, Carlos Gonzalez-Gonzalez, Nicola Nannola, et al.
Cancers, 2026