Lazaro Hiram Betancourt Nunez

Verified @med.lu.se

Associate Researcher, Department of Translational Medicine,Skåne University Hospital Malmö
Lund University

RESEARCH, TEACHING, or OTHER INTERESTS

Cancer Research, Molecular Medicine, Multidisciplinary, Biotechnology

1806

Scholar Citations

25

Scholar h-index

41

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Identifying Ferroptosis Inducers, HDAC, and RTK Inhibitor Sensitivity in Melanoma Subtypes through Unbiased Drug Target Prediction
    I Pla, BL Szabolcs, PN Peter, Z Ujfaludi, Y Kim, P Horvatovich, A Sanchez, ...
    bioRxiv, 2024.02. 08.579424 2024

  • A time-efficient workflow to purify a library of alanine mutants of surface-exposed residues of the domain III of the envelope protein of dengue virus serotype 1
    L Gonzlez-Lodeiro, C Gonzlez, L Betancourt
    Micropublication Biology 2023 2023

  • A time-efficient workflow to purify a library of alanine mutants of surface-exposed residues of the domain III of the envelope protein of dengue virus serotype 1
    DM Prieto, AMM Dunn, AE Llumbet, LG Gonzlez-Lodeiro, MS Nez, ...
    microPublication Biology 2023 2023

  • Histopathology-assisted proteogenomics provides foundations for stratification of melanoma metastases
    M Kuras, LH Betancourt, R Hong, L Szadai, J Rodriguez, P Horvatovich, ...
    bioRxiv, 2023.09. 29.559755 2023

  • Proteogenomic Characterization Reveals Therapeutic Opportunities Related to Mitochondrial Function in Melanoma
    J Gil, Y Kim, V Doma, U akır, M Kuras, LH Betancourt, IP Parada, ...
    bioRxiv, 2022.10. 24.513481 2022

  • Method Matters: Exploring Alkoxysulfonate-Functionalized Poly(3,4-ethylenedioxythiophene) and Its Unintentional Self-Aggregating Copolymer toward Injectable Bioelectronics
    RO Abdelrazek H Mousa, David Bliman, Lazaro Hiram Betancourt, Karin Hellman ...
    Chem Mater. 34 (6), 2752-2763 2022

  • Mapping the melanoma plasma proteome (MPP) using single-shot proteomics interfaced with the WiMT database
    N Almeida, J Rodriguez, I Pla Parada, Y Perez-Riverol, N Woldmar, Y Kim, ...
    Cancers 13 (24), 6224 2021

  • Deep proteomic analysis on biobanked paraffine-archived melanoma with prognostic/predictive biomarker read-out
    L Szadai, E Velasquez, B Szeitz, NP Almeida, G Domont, LH Betancourt, ...
    Cancers 13 (23), 6105 2021

  • A biobanking turning‐point in the use of formalin‐fixed, paraffin tumor blocks to unveil kinase signaling in melanoma
    E Velasquez, L Szadai, Q Zhou, Y Kim, I Pla, A Sanchez, R Appelqvist, ...
    Clinical and Translational Medicine 11 (8) 2021

  • The human melanoma proteome atlas—Complementing the melanoma transcriptome
    LH Betancourt, J Gil, A Sanchez, V Doma, M Kuras, JR Murillo, ...
    Clinical and Translational Medicine 11 (7), e451 2021

  • The human melanoma proteome atlas—Defining the molecular pathology
    LH Betancourt, J Gil, Y Kim, V Doma, U akır, A Sanchez, JR Murillo, ...
    Clinical and Translational Medicine 11 (7), e473 2021

  • Proteogenomics Reveals how Metastatic Melanoma Modulates the Immune System to Allow Immune Evasion
    J Gil, Y Kim, B Szeitz, V Doma, U akır, NP de Almeida, YP Hagemeijer, ...
    bioRxiv, 2021.04. 10.439245 2021

  • Targeting the hydrophilic regions of recombinant proteins by MS via in-solution buffer-free trypsin digestion
    LH Betancourt, LA Espinosa, Y Ramos, M Bequet-Romero, EN Rodrguez, ...
    European Journal of Mass Spectrometry 26 (3), 230-237 2020

  • Novel functional proteins coded by the human genome discovered in metastases of melanoma patients
    A Sanchez, M Kuras, JR Murillo, I Pla, K Pawlowski, AM Szasz, J Gil, ...
    Cell biology and toxicology 36, 261-272 2020

  • Protein expression in metastatic melanoma and the link to disease presentation in a range of tumor phenotypes
    Y Kim, J Gil, I Pla, A Sanchez, LH Betancourt, B Lee, R Appelqvist, ...
    Cancers 12 (3), 767 2020

  • The hidden story of heterogeneous B-raf V600E mutation quantitative protein expression in metastatic melanoma—association with clinical outcome and tumor phenotypes
    LH Betancourt, AM Szasz, M Kuras, J Rodriguez Murillo, Y Sugihara, I Pla, ...
    Cancers 11 (12), 1981 2019

  • Clinical protein science in translational medicine targeting malignant melanoma
    J Gil, LH Betancourt, I Pla, A Sanchez, R Appelqvist, T Miliotis, M Kuras, ...
    Cell biology and toxicology 35, 293-332 2019

  • Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data
    LH Betancourt, K Pawłowski, J Eriksson, AM Szasz, S Mitra, I Pla, ...
    Scientific reports 9 (1), 5154 2019

  • Challenging the heterogeneity of disease presentation in malignant melanoma—impact on patient treatment
    A Marcell Szasz, J Malm, M Rezeli, Y Sugihara, LH Betancourt, D Rivas, ...
    Cell Biology and Toxicology 35, 1-14 2019

  • Correction: automated phosphopeptide enrichment from minute quantities of frozen malignant melanoma tissue
    JR Murillo, M Kuras, M Rezeli, T Miliotis, L Betancourt, G Marko-Varga
    Plos one 13 (12), e0210234 2018

MOST CITED SCHOLAR PUBLICATIONS

  • Activation of Rho through a cross‐link with polyamines catalyzed by Bordetella dermonecrotizing toxin
    M Masuda, L Betancourt, T Matsuzawa, T Kashimoto, T Takao, ...
    The EMBO Journal 2000
    Citations: 134

  • CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo
    SE Perea, O Reyes, I Baladron, Y Perera, H Farina, J Gil, A Rodriguez, ...
    Molecular and cellular biochemistry 316, 163-167 2008
    Citations: 125

  • Primary structure of two cytolysin isoforms from Stichodactyla helianthus differing in their hemolytic activity.
    V Huerta, V Morera, Y Guanche, G Chinea, LJ Gonzalez, L Betancourt, ...
    Toxicon 39 (8), 1253-1256 2001
    Citations: 90

  • Differentiating α‐and β‐aspartic acids by electrospray ionization and low‐energy tandem mass spectrometry
    LJ Gonzlez, T Shimizu, Y Satomi, L Betancourt, V Besada, G Padrn, ...
    Rapid Communications in Mass Spectrometry 14 (22), 2092-2102 2000
    Citations: 90

  • Automated interpretation of low‐energy collision‐induced dissociation spectra by SeqMS, a software aid for de novo sequencing by tandem mass spectrometry
    J Fernandez‐de‐Cossio, J Gonzalez, Y Satomi, T Shima, N Okumura, ...
    ELECTROPHORESIS: An International Journal 21 (9), 1694-1699 2000
    Citations: 89

  • Outer membrane vesicles of the VA‐MENGOC‐BC vaccine against serogroup B of Neisseria meningitidis: Analysis of protein components by two‐dimensional
    L Uli, L Castellanos‐Serra, L Betancourt, F Domnguez, R Barber, ...
    Proteomics 6 (11), 3389-3399 2006
    Citations: 88

  • A novel fusion protein domain III-capsid from dengue-2, in a highly aggregated form, induces a functional immune response and protection in mice
    I Valds, L Bernardo, L Gil, A Pavn, L Lazo, C Lpez, Y Romero, ...
    Virology 394 (2), 249-258 2009
    Citations: 84

  • Automated interpretation of high‐energy collision‐induced dissociation spectra of singly protonated peptides by ‘seqms', a software aid for de novo sequencing by
    J Fernandez‐de‐Cossio, J Gonzalez, L Betancourt, V Besada, G Padron, ...
    Rapid communications in mass spectrometry 12 (23), 1867-1878 1998
    Citations: 64

  • Proteome analysis of Leishmania (Viannia) braziliensis by two-dimensional gel electrophoresis and mass spectrometry
    P Cuervo, JB de Jesus, M Junqueira, L Mendona-Lima, LJ Gonzlez, ...
    Molecular and biochemical parasitology 154 (1), 6-21 2007
    Citations: 61

  • CIGB-300, a synthetic peptide-based drug that targets the CK2 phosphoaceptor domain. Translational and clinical research
    SE Perea, I Baladron, Y Garcia, Y Perera, A Lopez, JL Soriano, N Batista, ...
    Molecular and cellular biochemistry 356, 45-50 2011
    Citations: 49

  • Automated interpretation of mass spectra of complex mixtures by matching of isotope peak distributions
    J Fernndez‐de‐Cossio, LJ Gonzalez, Y Satomi, L Betancourt, Y Ramos, ...
    Rapid Communications in Mass Spectrometry 18 (20), 2465-2472 2004
    Citations: 48

  • Isoelectric point optimization using peptide descriptors and support vector machines
    Y Perez-Riverol, E Audain, A Millan, Y Ramos, A Sanchez, JA Vizcano, ...
    Journal of proteomics 75 (7), 2269-2274 2012
    Citations: 47

  • Quantitative assessment of urea in-solution Lys-C/trypsin digestions reveals superior performance at room temperature over traditional proteolysis at 37 C
    LH Betancourt, A Sanchez, I Pla, M Kuras, Q Zhou, R Andersson, ...
    Journal of proteome research 17 (7), 2556-2561 2018
    Citations: 45

  • Isotopica: a tool for the calculation and viewing of complex isotopic envelopes
    J Fernandez-de-Cossio, LJ Gonzalez, Y Satomi, L Betancourt, Y Ramos, ...
    Nucleic acids research 32 (suppl_2), W674-W678 2004
    Citations: 42

  • Clinical protein science in translational medicine targeting malignant melanoma
    J Gil, LH Betancourt, I Pla, A Sanchez, R Appelqvist, T Miliotis, M Kuras, ...
    Cell biology and toxicology 35, 293-332 2019
    Citations: 37

  • In silico analysis of accurate proteomics, complemented by selective isolation of peptides
    Y Perez-Riverol, A Snchez, Y Ramos, A Schmidt, M Mller, L Betancourt, ...
    Journal of proteomics 74 (10), 2071-2082 2011
    Citations: 37

  • Identification of vimentin as a potential therapeutic target against HIV infection
    C Fernndez-Ortega, A Ramrez, D Casillas, T Paneque, R Ubieta, ...
    Viruses 8 (6), 98 2016
    Citations: 35

  • Levansucrase from Acetobacter diazotrophicus SRT4 Is Secreted via Periplasm by a Signal-Peptide-Dependent Pathway
    L Hernndez, J Arrieta, L Betancourt, V Falcn, J Madrazo, A Coego, ...
    Current microbiology 39, 146-152 1999
    Citations: 35

  • Proteomic study via a non-gel based approach of meningococcal outer membrane vesicle vaccine obtained from strain CU385: a road map for discovering new antigens
    J Gil, LH Betancourt, G Sardias, D Yero, O Niebla, M Delgado, D Garca, ...
    Human vaccines 5 (5), 347-356 2009
    Citations: 34

  • SCAPE: a new tool for the Selective CApture of PEptides in protein identification
    L Betancourt, J Gil, V Besada, LJ Gonzlez, J Fernndez-de-Cossio, ...
    Journal of proteome research 4 (2), 491-496 2005
    Citations: 33