ABHISHEK NIGAM
@ietlucknow.ac.in
ASSISTANT PROFESSOR
Institute of Engineering and Technology (IET), Lucknow, Uttar Pradesh
Teaching Area/Subjects: - Biomedical Engineering, Anatomy Physiology, Biomedical Instrumentation, Digital Electronics, Microprocessor, Electronics and Measurements, Control and measurements etc.
EXPERIENCE
• Three years of teaching experience at Sambhunath Engineering College, Prayagraj, from August 2010 to June 2013.
• M. Tech from (2013-2015) from MNNIT ALLAHABAD.
• One year of teaching experience at Sambhunath Engineering College, Prayagraj, from August 2015 to June 2016.
• Two years working as a TA (during in CIR Lab MNNIT ALLAHABAD for SEM/XRD (2017-2018).
• Ph.D. completed (2022) from MNNIT ALLAHABAD
• Six months of teaching experience at IERT, Prayagraj, (after Ph.D. Open Seminar- 12 July 2021) from August 2021 to Feb 2022.
• Worked as a Principal at RAJ Polytechnic, Varanasi (Uttar Pradesh), PIN-221004, INDIA (From Feb 2022 to Oct 2022)
• Currently working as an Assistant Professor at IET, LUCKNOW.
EDUCATION
Ph.D. (completed on 21/09/2022)
Motilal Nehru National Institute of Technology-Allahabad, U.P.
NIRF Ranking- 47 (2022)
Thesis Title: “Chemical Synthesis and Characterization of Zn and Mg Metal Oxides and Spinel Ferrites for Biomedical Applications”
Supervisor: Prof. S. J. Pawar
CGPA: 7.8 (on a scale of 10)
Publications: - 21, SCI-11, Scopus-5, Book Chapter-1, National/International Conferences -4
1-Patent
Source: - Google Scholar link: -
M. Tech: Biomedical Engineering
Motilal Nehru National Institute of Technology Allahabad, U.P.
NIRF Ranking- 47 (2022)
Dissertation: “Modelling and Simulation of Human Inner Ear”
Supervisor: Prof. S. J. Pawar
CGPA: 6.80 (on a scale of 10)
Northern India Engineering College, Lucknow, U.P
B. Tech: Electronics and Instrumentation Engineering
RESEARCH INTERESTS
Electronics, Instrumentation, Biomedical, Drug delivery, Synthesis of Nanoparticles, Biological Assay
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Avinash Tripathi, Abhishek Nigam, and S. J. Pawar
Informa UK Limited
Abstract The x-ray diffraction analysis manifested the single phases of Fe2O3, SmFeO3, and v SmFeO3 synthesized via sol-gel route. The Fe2O3, SmFeO3, and v SmFeO3 were hexagonal, orthorhombic, and cubic, respectively. The Debye-Scherer formula was used to calculate the average crystallite size of Fe2O3 (85.54 nm), SmFeO3 (67.65 nm), and v SmFeO3 (49.58 nm). The FESEM reveals near-spherical morphology with average particle sizes of 173, 114, and 161 nm, respectively. VSM analysis revealed the enhanced magnetic behavior of SmFeO3 and v SmFeO3 compared to Fe2O3. Antimicrobial activity against both E. coli and S. aureus bacteria justifies the biomedical application.
Abhishek Nigam, Bharat Singh, Sheetal Saini, Ambak Kumar Rai, and S. J. Pawar
Informa UK Limited
Shagun Varshney, Abhishek Nigam, Nidhi Mishra, and S. J. Pawar
Springer Science and Business Media LLC
Abhishek Nigam, Sheetal Saini, Bharat Singh, Ambak Kumar Rai, and S.J. Pawar
Elsevier BV
Abhishek Nigam, Kishor Kalauni, and S. J. Pawar
Informa UK Limited
ABSTRACT The nano-sized magnesium doped zinc ferrite (MgxZn1-xFe2O4 for x = 0.2 and 0.6) has been synthesised for biomedical application through two different routes (sol–gel and hydrothermal). The x-ray diffraction pattern showed the single phase of ferrite. The crystallite sizes and lattice parameters of Mg-Zn ferrite were obtained by three different methods viz. Scherrer formula (X’pert high score), Maud analysis (Rietveld refinement software), and Williamson Hall Plot. The field emission scanning electron microscopy revealed the near-spherical and dumbbell-shaped morphology of Mg-Zn ferrite. The vibrating sample magnetometer showed the increasing magnetic properties on increasing Mg doping. The elemental dispersive spectroscopy analysis revealed the presence of desired elements. The antimicrobial assay against E. coli (gram-negative) and S. aureus (gram-positive) bacteria showed a clear zone of inhibition. The Mg-Zn ferrite showed good magnetic and antimicrobial properties synthesised via the sol–gel route, which can be further used for possible drug delivery applications.
Shagun Varshney, Abhishek Nigam, Anirudh Singh, Sintu Kumar Samanta, Nidhi Mishra, and R.P. Tewari
Informa UK Limited
ABSTRACT The present work reports a novel method for fabricating nanocomposites (NCs) using Magnesium Oxide (MgO) and Zinc Oxide (ZnO) nanoparticles (NPs) via modified sol-gel route. Furthermore, hydroxyapatite was composited with MgO/ZnO NCs to form (HA)-based bio-ceramics (BCs) with enhanced antibacterial and mechanical properties. X-ray diffraction, Fourier transform infrared spectroscopy, field emission scanning electron and transmission electron microscopy, and energy-dispersive spectroscopy were used to perceive their structural and morphological characteristics. Selective area electron diffraction patterns confirm the plane obtained in XRD analysis. The average particle sizes for NPs and NCs were 50–60 nm, 80–120 nm, and 95–130 nm, respectively. The BCs with the mass of HA = 9.6 g and NC = 0.4 g exhibited minimum extension against applied load. It also showed better antibacterial activity against B. subtilis, S. aureus, and E. coli. Thus, BCs are suitable candidates for developing artificial bones and biomedical implants .
Shagun Varshney, Abhishek Nigam, S. J. Pawar, and Nidhi Mishra
Informa UK Limited
Abstract Silica has drawn the attention of many researchers from all over the world owing to its excellent biological, mechanical, and physiochemical properties. Different synthetic routes, reagents, characterization techniques, and applications of silica nanoparticles (SiO2 NPs) are discussed in this review article. A detailed discussion on sol-gel, ultrasonication, chemical precipitation, and hydrothermal route is presented. Biological synthesis of SiO2 NPs from bamboo leaves, rice husk, and sugarcane bagasse is also focused. Different characterization techniques including X-ray diffraction, dynamic light scattering, transmission electron microscopy, and Fourier transform infrared spectroscopy are discussed in detail. A study on SiO2 NPs conjugated with metallic oxides and polymers is also discussed. Being important materials with a wide variety and novel applications, these conjugates are used in agriculture, mechanical engineering, material science, electronics, and biomedical engineering. However, greater emphasis has been laid on biomedical aspects, including antibacterial applications and drug delivery along with its cytotoxic properties. The review article reflects that SiO2 NPs are potential candidates for several biomedical applications due to their biocompatibility and appreciable biological activity. Graphical Abstract
Abhishek Nigam and S. J. Pawar
Informa UK Limited
ABSTRACT In the present study, a hydrothermal method has been used to optimise five morphologies of ZnO by varying the process parameters for biomedical applications. X-ray diffraction (XRD) patterns have revealed the single phases of ZnO peaks with hexagonal wurtzite structure. The crystallite sizes of different ZnO samples were depicted as 37.99 nm, 52.51 nm, 61.26 nm, 62.14 nm, and 66.02 nm, respectively. The field emission scanning electron microscopy (FE-SEM) shows that ZnO powders have different morphologies like hexagonal rod-like, flakes-like, spindle-like, flower-like, and dumbbell-shaped. The ZnO particles are randomly orientated, and the average particle sizes are 230 nm, 80 nm, 203 nm, 207 nm, and 320 nm, respectively. The elemental dispersive spectroscopy (EDS) reveals that only Zinc (Zn) and Oxygen (O) peaks are available, and no other impurities have been found. The photoluminescence (PL) shows that samples have different absorptions intensities. The 5-Flourouracil (anticancer drug) was successfully loaded and its slow-release profile has been investigated. The drug loading and drug release profile show the potential for drug delivery. The antimicrobial activity shows a significant zone of inhibition (ZOI) against both gram-negative (E. coli) and gram-positive (S. aureus) bacteria. The maximum ZOI is shown for spindle shaped ZnO against both bacteria.
Shagun Varshney, Abhishek Nigam, S.J. Pawar, and Nidhi Mishra
Informa UK Limited
ABSTRACT The present study reports a novel technique to synthesise silica nanoparticles through modified sol-gel, ultrasonication, and hydrothermal routes. Physio-chemical and structural characterization was carried out using X-ray diffraction, high resolution scanning electron microscopy, energy dispersive spectroscopy, dynamic light scattering, Fourier transform infrared spectroscopy, ultraviolet-visible, and photoluminescence spectroscopy. The particle size determination revealed the spherical structure of nanoparticles with an average diameter of 85 nm and between 90-170 nm through HRSEM and DLS respectively. Stretching and vibration bands confirming the presence of SiO2 were obtained in FTIR analysis. Spectra from UV-vis and PL spectroscopy were obtained at a maximum wavelength of 233 nm and 555 nm respectively. The anti-microbial effect of SiO2 nanoparticles against E. coli and S. aureus bacteria revealed the appreciable response which renders them for many biomedical applications like drug delivery. The cytotoxicity of SiO2 nanoparticles on human lung epithelial (A549) cell line revealed their non-toxic behavior.
Abhishek Nigam, Sheetal Saini, Ambak Kumar Rai, and S.J. Pawar
Elsevier BV
Abhishek Nigam, Sheetal Saini, Ambak Kumar Rai, and S.J. Pawar
Elsevier BV
A. Sinha, D. Sachan, Anisha, Ankur Vishal, Deepak Kumar, Naveen Kumar, A. Nigam and Deepak K. Singh
Zinc doped Nickel ferrites with chemical formula Ni(1−x)ZnxFe2O4 (x = 0.2, 0.4, 0.6, and 0.8) were synthesized using both Sol-gel auto-combustion and Hydrothermal methods. The synthesized powders were characterized for their physical and magnetic properties. The crystal structure and lattice parameter of these compounds were investigated by X-ray diffraction (XRD) and morphology has been confirmed by Scanning Electron Microscopy (SEM). The magnetic properties of after-calcined nanoparticles were measured at room temperature using a vibrating sample magnetometer (VSM). X-ray diffraction of these samples shows the presence of a single-phase cubic spinel ferrite structure. The VSM analysis indicates that the Zn content has a significant influence on the magnetic properties such as Saturation Magnetization (Ms), Coercivity (Hc), and Remanence (Mr). The doping concentration of Zn increase with an increase of x which causes a significant increase in the Ms from x=0.2 to 0.4 then decrease from x=0.6 to 0.8. A critical Rietveld analysis of XRD reveals the presence of a very small amount of NiO phase along with the ferrite phase. The Rietveld analysis also confirms the crystallite size and lattice parameter.
Abhishek Kumar, A. Nigam, Samarjit Singh, S. Singh and Rahul Singh
Naveen Kumar, Deepak Singh, A. Nigam, O. Rajpoot, Mayank Kumar, Yadav, Yogendra Singh, P. S. Prakash and Samarjit Singh
Naveen Kumar, Ajaya Bharti, Manish Dixit, and Abhishek Nigam
Springer Science and Business Media LLC
Abhishek Nigam and S.J. Pawar
Elsevier BV
Abhishek Nigam and S.J. Pawar
Elsevier BV
RECENT SCHOLAR PUBLICATIONS
MOST CITED SCHOLAR PUBLICATIONS
Publications
[1]. Abhishek Nigam and Suryappa J Pawar, Structural, magnetic, and antimicrobial properties of zinc doped magnesium ferrite for drug delivery applications, Ceramics International Volume 46, Issue 4, March 2020, Pages 4058-4064, DOI: 10.1016/j. SCI, (
[2]. Abhishek Nigam, Sheetal Saini, Ambak Kumar Rai, Suryappa J Pawar, Structural, Optical, Cytotoxicity, and Antimicrobial Properties of MgO, ZnO and MgO/ZnO Nanocomposite for Biomedical Applications, March 2021Ceramics International Volume 47, Issue 14, 15 July 2021, Pages 19515-19525, DOI: 10.1016/j. (SCI),
[3]. Abhishek Nigam, Sheetal Saini, Ambak Kumar Rai, Suryappa J Pawar, Structural, morphological, antimicrobial, and cytotoxicity study of spindle-shaped ZnO submicron particles for potential biomedical applications, July 2021 Materials Today Communications 28(18):102683 DOI: 10.1016/j. (SCI),
[4]. Abhishek Nigam, Sheetal Saini, Bharat Singh, Ambak Kumar Rai, Suryappa J Pawar, Zinc doped Magnesium ferrite nanoparticles for evaluation of biological properties viz antimicrobial, biocompatibility, and in vitro cytotoxicity, June 2022, Materials Today Communications, Volume 31, 103632 DOI: 10.1016/j. (SCI),
[5]. Abhishek Nigam and Suryappa J Pawar, Structural, optical, antimicrobial properties with drug loading and drug release of five different ZnO nano and sub-micron particles for biomedical applications,
RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)
Mr. R. Balamurugan, Mr. Ubaid Ahmad Khan, Dr. Abhishek Nigam, Dr. U. Arunkumar, Mr. S. Madhankumar, Mr. S. Rajesh, Dr. T. A. Selvan, A Supervision Technique and Machine for Determining A Gear-Stick Spot, And A Vehicle Control System, Application A, Date of filing application: - 01/05/2022, Date of published: - 03/06/2022. (Patent)