Alexandre Prola

@unige.ch

Faculty of Medicine, Department of Cell Physiology and Metabolism
University of Geneva



              

https://researchid.co/alexandreprola
1668

Scholar Citations

19

Scholar h-index

20

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • mTORC1-dependent SOCE activity regulates synaptic gene expression and muscle response to denervation
    A Prola, O Dupont, J Rajendran, F Chabry, S Koenig, M Frieden, ...
    bioRxiv, 2024.04. 01.587665 2024

  • Identification of a muscle-specific isoform of VMA21 as a potent actor in X-linked myopathy with excessive autophagy pathogenesis
    I Cocchiararo, O Cattaneo, J Rajendran, F Chabry, M Cornut, H Soldati, ...
    Human Molecular Genetics 32 (24), 3374-3389 2023

  • Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease
    N Khadhraoui, A Prola, A Vandestienne, J Blondelle, L Guillaud, ...
    Molecular metabolism 69, 101677 2023

  • PINK1 Deficiency Alters Muscle Stem Cell Fate Decision And Muscle Regenerative Capacity.
    G Cairns, M Thumiah-Mootoo, MR Abbasi, J Racine, N Lariovov, A Prola, ...
    bioRxiv, 2023.06. 23.546123 2023

  • Cardiolipin alterations during obesity: exploring therapeutic opportunities
    A Prola, F Pilot-Storck
    Biology 11 (11), 1638 2022

  • Metabolic regulation of adult muscle stem cells
    A Prola, L Neff, O Dorchies, V Allamand, F Relaix, P Castets
    Myologie 2022 2022

  • Punicalagin targets atherosclerosis: gene expression profiling of THP-1 macrophages treated with punicalagin and molecular docking
    E Huwait, S Almowallad, R Al-Massabi, S Saddeek, K Gauthaman, ...
    Current Issues in Molecular Biology 44 (5), 2153-2166 2022

  • Thymoquinone (TQ) inhibits inflammation and migration of THP-1 macrophages: mechanistic insights into the prevention of atherosclerosis using in-vitro and in-silico analysis
    E Huwait, N Al-Gharawi, MA Al-Ghamdi, M Gari, A Prola, ...
    Current Issues in Molecular Biology 44 (4), 120 2022

  • Isolation and Phospholipid Enrichment of Muscle Mitochondria and Mitoplasts
    A Prola, A Vandestienne, N Baroudi, F Joubert, L Tiret, F Pilot-Storck
    Bio-protocol 11 (20), e4201-e4201 2021

  • Endurance is improved in female rats after living high-training high despite alterations in skeletal muscle
    A Malgoyre, A Prola, A Meunier, R Chapot, B Serrurier, N Koulmann, ...
    Frontiers in Sports and Active Living 3, 663857 2021

  • Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming
    J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier, Z Koumaiha, K Kefi, ...
    Cell metabolism 33 (2), 283-299. e9 2021

  • Perspectives on skeletal muscle stem cells
    F Relaix, M Bencze, MJ Borok, A Der Vartanian, F Gattazzo, ...
    Nature communications 12 (1), 692 2021

  • Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle
    A Prola, J Blondelle, A Vandestienne, J Piquereau, RGP Denis, S Guyot, ...
    Science advances 7 (1), eabd6322 2021

  • Punicalagin regulates key processes associated with atherosclerosis in THP-1 cellular model
    S Almowallad, E Huwait, R Al-Massabi, S Saddeek, K Gauthaman, ...
    Pharmaceuticals 13 (11), 372 2020

  • Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus
    L Delavalle, N Mathiah, L Cabon, A Mazeraud, MN Brunelle-Navas, ...
    Molecular metabolism 40, 101027 2020

  • Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus
    MN Brunelle-Navas, LK Lerner, M Tannoury, A Prola, ...
    2020

  • Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity
    A Prola, J Blondelle, A Vandestienne, J Piquereau, RGP Denis, S Guyot, ...
    bioRxiv, 715953 2019

  • Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes
    A Prola, Z Nichtova, J Pires Da Silva, J Piquereau, K Monceaux, ...
    Cardiovascular Research 115 (2), 328-342 2019

  • Stress du rticulum endoplasmique et physiopathologie cardiaque
    A Prola, C Lemaire, JL Samuel
    Biologie et pathologie du cœur et des vaisseaux 3e dition, 54 2019

  • Necroptosis mediates myofibre death in dystrophin-deficient mice
    JE Morgan, A Prola, V Mariot, V Pini, J Meng, C Hourde, J Dumonceaux, ...
    Nature communications 9 (1), 3655 2018

MOST CITED SCHOLAR PUBLICATIONS

  • Downregulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
    J Piquereau, F Caffin, M Novotova, A Prola, A Garnier, P Mateo, D Fortin, ...
    Cardiovascular Research 2012
    Citations: 204

  • Perspectives on skeletal muscle stem cells
    F Relaix, M Bencze, MJ Borok, A Der Vartanian, F Gattazzo, ...
    Nature communications 12 (1), 692 2021
    Citations: 203

  • SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation
    A Prola, J Pires Da Silva, A Guilbert, L Lecru, J Piquereau, M Ribeiro, ...
    Cell Death & Differentiation 24 (2), 343-356 2017
    Citations: 188

  • Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming
    J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier, Z Koumaiha, K Kefi, ...
    Cell metabolism 33 (2), 283-299. e9 2021
    Citations: 133

  • Hypothalamic AgRP‐neurons control peripheral substrate utilization and nutrient partitioning
    A Joly‐Amado, RGP Denis, J Castel, A Lacombe, C Cansell, C Rouch, ...
    The EMBO journal 31 (22), 4276-4288 2012
    Citations: 129

  • Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway
    M Boussabbeh, I Ben Salem, A Prola, A Guilbert, H Bacha, S Abid-Essefi, ...
    Toxicological sciences 144 (2), 328-337 2015
    Citations: 120

  • Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2
    C Gallerne, A Prola, C Lemaire
    Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (6), 1356-1366 2013
    Citations: 99

  • Necroptosis mediates myofibre death in dystrophin-deficient mice
    JE Morgan, A Prola, V Mariot, V Pini, J Meng, C Hourde, J Dumonceaux, ...
    Nature communications 9 (1), 3655 2018
    Citations: 83

  • Crocin and Quercetin protect HCT116 and HEK293 cells from Zearalenone-induced apoptosis by reducing endoplasmic reticulum stress
    IB Salem, A Prola, M Boussabbeh, A Guilbert, H Bacha, S Abid-Essefi, ...
    Cell Stress and Chaperones 20 (6), 927-938 2015
    Citations: 79

  • Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy
    N Diguet, Y Mallat, R Ladouce, G Clodic, A Prola, E Tritsch, J Blanc, ...
    Journal of Biological Chemistry 286 (40), 35007-35019 2011
    Citations: 69

  • HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth
    J Blondelle, Y Ohno, V Gache, S Guyot, S Storck, N Blanchard-Gutton, ...
    Journal of molecular cell biology 7 (5), 429-440 2015
    Citations: 51

  • Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1‐deficient mice
    F Caffin, A Prola, J Piquereau, M Novotova, DJ David, A Garnier, D Fortin, ...
    The Journal of physiology 591 (23), 6017-6037 2013
    Citations: 49

  • Crocin and quercetin prevent PAT‐induced apoptosis in mammalian cells: Involvement of ROS‐mediated ER stress pathway
    M Boussabbeh, A Prola, I Ben Salem, A Guilbert, H Bacha, C Lemaire, ...
    Environmental toxicology 31 (12), 1851-1858 2016
    Citations: 47

  • Activation of ER stress and apoptosis by α-and β-zearalenol in HCT116 cells, protective role of Quercetin
    IB Salem, A Prola, M Boussabbeh, A Guilbert, H Bacha, C Lemaire, ...
    Neurotoxicology 53, 334-342 2016
    Citations: 40

  • Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes
    A Prola, Z Nichtova, J Pires Da Silva, J Piquereau, K Monceaux, ...
    Cardiovascular Research 115 (2), 328-342 2019
    Citations: 36

  • Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus
    L Delavalle, N Mathiah, L Cabon, A Mazeraud, MN Brunelle-Navas, ...
    Molecular metabolism 40, 101027 2020
    Citations: 27

  • Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle
    A Prola, J Blondelle, A Vandestienne, J Piquereau, RGP Denis, S Guyot, ...
    Science advances 7 (1), eabd6322 2021
    Citations: 26

  • Crocin protects human embryonic kidney cells (HEK293) from α-and β-zearalenol-induced ER stress and apoptosis
    I Ben Salem, M Boussabbeh, A Prola, A Guilbert, H Bacha, C Lemaire, ...
    Environmental Science and Pollution Research 23, 15504-15514 2016
    Citations: 26

  • Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress
    A Salah, C Bouaziz, A Prola, J Pires Da Silva, H Bacha, S Abid-Essefi, ...
    Journal of Toxicology and Environmental Health, Part A 80 (23-24), 1230-1241 2017
    Citations: 19

  • Punicalagin regulates key processes associated with atherosclerosis in THP-1 cellular model
    S Almowallad, E Huwait, R Al-Massabi, S Saddeek, K Gauthaman, ...
    Pharmaceuticals 13 (11), 372 2020
    Citations: 11