*Dr. Saif Sami Al-Mudhaffar**
Consultant Cardiac Surgeon | Fellowship in Cardiothoracic Surgery**
Dr. Saif Sami Al-Mudhaffar is a consultant cardiac surgeon with a fellowship in cardiothoracic surgery and significant experience in complex cardiovascular procedures, including mitral valve replacement, coronary artery bypass grafting, and aortic root surgery actively engaged in clinical research with a focus on cardiac surgery outcomes,
EDUCATION
consultant cardiac surgeon
RESEARCH, TEACHING, or OTHER INTERESTS
Surgery, Cardiology and Cardiovascular Medicine, Infectious Diseases, Multidisciplinary
Cardiac myxoma following transcatheter closure of an atrial septal defect Saif Sami Al-modhaffer, Ali Abdulamir Mohammed, Okba F. Ahmed, Fahmi H. Kakamad, Dana H. Mohammed Saeed, et al. Baylor University Medical Center Proceedings, 2024 To date, no significant association has been reported between atrial septal defects (ASD) and cardiac myxomas. This study reports a 56-year-old woman with cardiac myxoma following transcatheter closure of ASD. She presented with a 3-month history of recurrent dizziness, vertigo, palpitations, and generalized weakness after undergoing ASD occlusion a year earlier. Echocardiography and cardiac computed tomography scans identified a large, mobile mass (7.2 cm × 2.8 cm) in the left atrium, protruding through the mitral valve. The patient underwent median sternotomy and pericardiotomy, and the histopathological examination confirmed the diagnosis of atrial myxoma. The current case illustrates the challenges in determining whether an atrial mass is a benign myxoma or a dangerous thrombus. While there is no definitive link between the implantation of an ASD closure device and the formation of a myxoma, the emergence of this tumor is a potential occurrence.
Operative management and outcomes in patients with myxomas: A single-center experience Ahmed Abdulfattah Alhasso, Okba F. Ahmed, Dana H. Mohammed-Saeed, Fahmi H. Kakamad, Saif S. Almodhaffer, et al. Frontiers in Surgery, 2023 BackgroundCardiac myxoma is a rare cardiac tumor that may be asymptomatic or can cause embolization or intracardiac obstruction, leading to heart failure, sudden cardiac death, and arrhythmia. This study aims to report an 11-year experience of a single center in the management of cardiac myxoma.MethodThis study is a single-center retrospective case series. Eighty cases of cardiac myxoma were collected in Ibn Albitar's specialized center for cardiac surgery. Transthoracic echocardiography was used to make the preoperative diagnosis in all patients. The surgeries were undertaken through the standard approach of a median sternotomy. All four cardiac chambers were thoroughly explored for additional myxomas. The major objective of the operations was complete tumor resection.ResultThe mean age of the patients was 46.3 years. Females (67.5%) were predominant over males (32.5%). Shortness of breath was the most common symptom (86.25%). The left atrium was the most affected site (83.75%), followed by the right atrium (13.75%). Coronary artery bypass grafting was required as the secondary or associated intervention in 19 (23.75%) cases. The recurrence rate was 11.25%, with a mortality rate of 3.75%.ConclusionRecurrence and tumor embolism are risks of surgical intervention for myxoma. Good preparation using transthoracic echocardiography as a diagnostic tool and standard median sternotomy to complete resection of the tumors can decrease the rate of recurrence, embolism, and even mortality.
Combined operation for coronary artery bypass grafting and mitral valve replacement; risk and outcome Okba F. Ahmed, Fahmi H. Kakamad, Saif S. Almudhaffar, Rafid Hameed Hachim, Kayhan A. Najar, et al. International Journal of Surgery Open, 2021 Introduction: The combination of mitral valve replacement (MVR) with coronary artery bypass grafting (CABG) is generally thought to have a greater early and late mortality than either procedure alone. The aim of this study is to review single center experience for the concomitant MVR and CABG. Patients and methods: This is a single center, retrospective, single cohort study, composes of consecutive cases. It included all the cases of combined operation of MVR and CABG. The patients were followed up for a median duration of two years (six months to four years). The data were collected from hospital records and registers of hospital statistics. The followings were obtained; socio-demographic data, information regarding clinical courses, intraoperative findings, and post-operative follow up data. Result: The study included 72 cases, the mean age was 56 years, 38 of them (53%) were males and 34 (47%) were female. The most common comorbidity was hypertension which was found in 24 patients (33%). The mean preoperative ejection fraction was 59%. Twenty-two patients (30.6%) had single graft, 21 patients (29.2%) underwent 3-vessel grafting, 16 patients (22.2%) had 2-vessel grafting, and 13 cases (18.1%) underwent 4-vessel grafting. The CPB duration ranged from 108 to 280 min with a mean of 182 min and cross-clamp time ranged from 80 to 186 min with a mean of 122 min. The most common complication was plural effusion which occurred in 8 cases (11.1%) and managed by aspiration. Overall mortality was 8.3% (4 patients). Conclusion: CABG and chordal-sparing and posterior leaflet replacement has favorable outcome, as well as minimizes the need of redo surgery as in repair.one of the best options for CAD and sever MR. Highlights
Evaluation of Ceruloplasmin ferroxidase activity and lipid profiles in patients with Valvular heart diseases H K Sacheat, S Z Husseinand, S S Al-Mudhaffar Journal of Physics Conference Series, 2021 One of the major health problems causing defects or damage to one or more of the four heart valves [aortic, mitral, pulmonary, and tricuspid] is valvular heart disease [VHD]; it occurs due to congenital abnormalities or acquired pathology. It is a defect that results in weak heart valves and is therefore unable to function as precise pathways of the blood. The aim of the current study was to evaluate the ferroxidase activity of ceruloplasmin (Cp) and the lipid profile of valvular heart disease patients in sera. Ninety subjects were included in this study and 60 patients with HDV were divided into two subgroups according to the affected valve: 33 patients with aortic valve disease (AV) and 27 patients with mitral valve disease (MV group). In addition, 30 healthy individuals were registered in all groups as control(C) group Serum copper (Cu), total protein (TP), activity and specific activity of ferroxidase Cp, and lipid profile were measured. The results showed that there was a highly significant increase in patient (AV & MV) groups compared to the C group in activity, specific Cp and Cu activity levels. In addition, compared to the C group, triglyceride (TG) and very low density lipoprotein (VLDL) levels showed a highly significant increase in the AV and MV groups. No significant differences were found between patients and control groups in TP, Total Cholesterol (TC), Low Density Lipoprotein Cholesterol (LDL-C) & High Density Lipoprotein Cholesterol (HDL-C) levels. Likewise, for all parameters, there were no significant differences between the AV and MV groups. In conclusion, the high serum level of Cu and the activity of Cp ferroxidase may be considered to be a risk factor for VHD.
ESTIMATION OF OXIDATIVE STRESS AND SOME RELATED PARAMETERS IN IRAQI PATIENTS WITH VALVULAR HEART DISEASES Biochemical and Cellular Archives, 2020
Cardiac hydatid disease; misleading presentations, a case series Ashur Y. Oraha, Saif Sami Al-modhaffer, Okba F. Ahmed, Wisam S. Al obaidy, Aram Baram, et al. International Journal of Surgery Open, 2020 Introdcution: Cardiac echinococcosis is a zoonotic parasitic infection that necessitates a high index of suspicion in endemic areas. The purpose of this study is to introduce different clinical scenarios of four cases in two major cardiac centers. Methods: A retrospective, case series study, conducted in three centers for the last two years. Addressing each case separately in regard to presentation and management. Results: Four cases have been reported, three patients were female 75% and one patient was male 25%. Age ranged from 27 to 32 years. All the patients 100% had dyspnea as their main first presentation, one patient (25%) presented as pulmonary embolism with three attacks of hemoptysis. One patient (25%) had an attack of convulsion 25%. Different segments of the heart were involved, Left ventricle was involved in 50%, Right ventricle in 25%, combined pulmonary and pericardial involvement in another 25%. Median Sternotomy with the cardioplegic arrest was performed in three patients 75% and Posterolateral thoracotomy was the approach in one case 25%. Conclusion: Cardiac Hydatid cyst is a sparse yet potentially perilous clinical entity. Early surgical intervention is the modality of choice might halt unfavorable consequences. Highlights:
Publications
Almudhaffar, Saif S.
Ibn Al-Bitar Cardiac Centre, Baghdad, Iraq
Scopus ID: 57408394600
0009-0006-7580-286X