Soluble CD36 Concentration in Diabetic Hypertensive Patients with Coronary Atherosclerosis Amer Ali Khaleel, Ruqaya Mohammed Ghareeb Taher Al-Barzinji Cellular and Molecular Biology, 2022 Atherosclerosis is a chronic condition defined by cholesterol retention and arterial wall inflammation. CD36 is indeed a membrane protein found in the monocyte-macrophage systems and endothelial cells involved in the cellular uptake of oxidized low-density lipoproteins and long-chain fatty acids with a crucial role in the pathophysiology of atherosclerosis. The purpose of this research is to compare the diagnostic usefulness of soluble CD36 (sCD36) to high sensitivity C reactive protein (hs-CRP) in diabetic hypertensive individuals with coronary atherosclerosis and the correlation between these parameters in research groups. One hundred individuals with coronary atherosclerosis were divided into four groups based on diabetes mellitus (DM) and/or hypertension (HTN), with 100 participants with routine angiography serving as a control group. The serum levels of sCD36 and hs-CRP were quantified using a sandwich enzyme-linked immunosorbent assay (ELISA) for sCD36 and a particle-enhanced immune turbidimetric assay for hs-CRP, respectively. A study group's lipid profiles, hematological markers, and clinical aspects were compared. Compared to the control, sCD36 and hs-CRP levels in patients increased considerably (p<0.05). The sCD36 level varied substantially between groups (p<0.05), with the DM-HTN group having the highest sCD36 level among the patient groups. Further, the hs-CRP level indicated a significant difference among patients and controls (p<0.05). CD36 correlated significantly and positively with the following terms BMI, hs-CRP, Total cholesterol and non-HDL-C (p<0.05).
Procalcitonin as New Proinflammatory Marker in Burn Patients Amer A. Khaleel, Ruqaya M. Al-Barzinji Polytechnic Journal, 2021 Procalcitonin (PCT) is a 116 amino acid peptide with a sequence identical to that of prohormone of calcitonin but devoid of hormonal activity. The aim of this study was to determine PCT and it using as a new prognostic pro-inflammatory marker in burn patients and determine the role of PCT level as a mortality indicator in survival and non-survival burn patients. The burn patients in this study were divided into four groups according to the percentage of total body surface area burned carry out on (50) burn patients admitted to the burn unit in West Erbil Emergency Hospital in Erbil governorate and (20) apparently the healthy non-burn individuals who regarded as healthy control group (HC) in this study from February 2012 to April 2012. Out of 50 burnt patients, 20 patients were second sampled to follow-up their immune profile. Regarding PCT there were significant differences (P < 0.05) observed between the mean serum concentration of PCT belong to 18 burn patients of 1st group (G1) (1.24 ± 0.82), 23 patients of 2nd group (G2) (1.52 ± 0.76), six patients of 3rd group (G3) (2. 16 ± 0.11), and three burn patients of 4th group (G4) (6.5 ± 2.87) with mean serum concentration of 18 HC (0.02 ± 0.006). Significant differences obtained when compared to G3 (2.16 ± 0.11) versus G4 (6.5 ± 2.87) using the F-test and t-test. Results show that PCT is a highly productive laboratory parameter involving an easy and rapid beside test for diagnosis and prognosis mortality in burn patients.
RECENT SCHOLAR PUBLICATIONS
Recent progress in DNAzyme-mediated CRISPR/Cas systems for the detection of non-nucleic acid targets HJ Azeez, JKM Abdalla, A Khaleel, RM Lamouki, A Gharibi, E Babaei Microchemical Journal, 114836 , 2025 2025 Citations: 2
Real-time biosensing of pathogenic bacteria with SERS-functionalized nucleic acid sensors: Promising new tools for ultrasensitive and multiplexed analysis STJ Balaky, SF Hamid, RS Uso, A Khaleel, A Gharibi Microchemical Journal 215, 114213 , 2025 2025 Citations: 7
Soluble CD36 concentration in diabetic hypertensive patients with coronary atherosclerosis AA Khaleel, RMGT Al-Barzinji Cellular and Molecular Biology 68 (1), 109-116 , 2022 2022 Citations: 8
Procalcitonin as new proinflammatory marker in burn patients AA Khaleel, RM Al-Barzinji Polytechnic Journal 11 (1), 12 , 2021 2021 Citations: 4
Screening for Helicobacter PyloriIgG among Undergraduate Student of Hawler Medical University/ College of Health Sciences SSA Amer Ali Khaleel, Sahar Mohammed Zaki Abdullah, Abdulrazzaq Bahaulddin ... Journal of Kirkuk Medical College 8 (1), 123-129 , 2020 2020 Citations: 3
Significance of Hepatitis B Virus Diagnosis by Real-time Polymerase Chain Reaction over Serological Markers in Hepatitis B Virus Patients SGH Amer A. Khaleel, Salah T. Jalal Cihan University-Erbil Scientific Journal (CUESJ) 4 (1), 52-56 , 2020 2020 Citations: 1
Molecular diagnosis in differentiating active and inactive forms of hepatitis b virus carriers STJ Balaky, SG Hussain, AA Khaleel, FT Sabeer, AH Mawlood Journal of University of Babylon for Pure and Applied Sciences 26 (10), 41-45 , 2018 2018 Citations: 1
Assessment of Neopterin and Interleukin-1 Beta Serum Levels in Burn Patients RM Al-Barzinji, AA Khaleel Diyala Journal of Medicine 11 (2), 25-33 , 2016 2016 Citations: 1
Effects of Fenugreek (Trigonella foenum-graecum) Seeds Aqueous Extract on the Tissue structure of Anterior Pituitary Gland and Some Organs of Reproductive System in Male Albino … AA Khaleel, KR Hamad 2011 Citations: 4
MOST CITED SCHOLAR PUBLICATIONS
Soluble CD36 concentration in diabetic hypertensive patients with coronary atherosclerosis AA Khaleel, RMGT Al-Barzinji Cellular and Molecular Biology 68 (1), 109-116 , 2022 2022 Citations: 8
Real-time biosensing of pathogenic bacteria with SERS-functionalized nucleic acid sensors: Promising new tools for ultrasensitive and multiplexed analysis STJ Balaky, SF Hamid, RS Uso, A Khaleel, A Gharibi Microchemical Journal 215, 114213 , 2025 2025 Citations: 7
Procalcitonin as new proinflammatory marker in burn patients AA Khaleel, RM Al-Barzinji Polytechnic Journal 11 (1), 12 , 2021 2021 Citations: 4
Effects of Fenugreek (Trigonella foenum-graecum) Seeds Aqueous Extract on the Tissue structure of Anterior Pituitary Gland and Some Organs of Reproductive System in Male Albino … AA Khaleel, KR Hamad 2011 Citations: 4
Screening for Helicobacter PyloriIgG among Undergraduate Student of Hawler Medical University/ College of Health Sciences SSA Amer Ali Khaleel, Sahar Mohammed Zaki Abdullah, Abdulrazzaq Bahaulddin ... Journal of Kirkuk Medical College 8 (1), 123-129 , 2020 2020 Citations: 3
Recent progress in DNAzyme-mediated CRISPR/Cas systems for the detection of non-nucleic acid targets HJ Azeez, JKM Abdalla, A Khaleel, RM Lamouki, A Gharibi, E Babaei Microchemical Journal, 114836 , 2025 2025 Citations: 2
Significance of Hepatitis B Virus Diagnosis by Real-time Polymerase Chain Reaction over Serological Markers in Hepatitis B Virus Patients SGH Amer A. Khaleel, Salah T. Jalal Cihan University-Erbil Scientific Journal (CUESJ) 4 (1), 52-56 , 2020 2020 Citations: 1
Molecular diagnosis in differentiating active and inactive forms of hepatitis b virus carriers STJ Balaky, SG Hussain, AA Khaleel, FT Sabeer, AH Mawlood Journal of University of Babylon for Pure and Applied Sciences 26 (10), 41-45 , 2018 2018 Citations: 1
Assessment of Neopterin and Interleukin-1 Beta Serum Levels in Burn Patients RM Al-Barzinji, AA Khaleel Diyala Journal of Medicine 11 (2), 25-33 , 2016 2016 Citations: 1
