Ana was graduated in Electrical and Computer Engineering (Instituto Superior Técnico, University of Lisbon), 1999, is MSc. in Health Engineering (Portuguese Catholic University), 2017, and PhD in Biomedical Sciences/Neurosciences (Faculty of Medicine, University of Lisbon), 2016. She lectured Assistive Technologies, Machine Learning and Computer Programming courses in Portuguese Universities and has been involved in many national and international R&D projects and multidisciplinary teams.
Ana is director of Value for Health CoLAB and investigator in Comprehensive Health Research Center, Nova Medical School.
EDUCATION
2016 - PhD in Biomedical Sciences (Neurosciences) Doctoral Programme in Neurosciences
Faculty of Medicine, University of Lisbon. Approved with Honours Distinction.
2007 - Master in Clinical Engineering
Universidade Católica Portuguesa. Approved with Excellent.
1999 - Electrical and Computer Engineering
Instituto Superior Técnico, University of Lisbon.
Features of Remote Patient Monitoring Systems That Implement Integrated Care: A Perspective Aligned With Current Challenges for Digital Health Technologies Comment on “Towards A Framework for Implementing Remote Patient Monitoring From an Integrated Care Perspective: A Scoping Review” Ana Londral International Journal of Health Policy and Management, 2025 This commentary elaborates on the model proposed by Miranda et al. for implementing Remote Patient Monitoring (RPM) from an integrated care perspective. It stresses the complexity of RPM deployment as a digital health technology (DHT) and discusses essential features that developers and procurement managers should take into consideration in RPM systems to facilitate the implementation of integrated care practices. Furthermore, three major challenges for DHT implementation that align with the the proposed RPM-based integrated care model are discussed: (1) the success of DHT in implementing a healthcare strategy requires elements of service innovation that align to the context of care delivery; (2) evidence generation methods influence the adoption of DHT and need an evolutive and multistakeholder perspective. (3) governance and policy strategies are crucial since they profoundly influence digital health priorities, investments and resource allocation within organizations and healthcare systems.
Multi-activity 3D printed assistive technology in children: A case study João Silva, Matilde Silva, Bruno Soares, Carla Quintão, Ana Rita Londral, et al. Assistive Technology, 2025 Congenital limb defects occur when a limb does not develop normally during pregnancy. The quality of each person's everyday life is significantly impacted by any of these defects and there is no concrete treatment. 3D modeling and printing, enables the creation and customization of precise virtual and/or physical models, including models of the human anatomy. These technologies provide a novel method of producing new devices with optimized design and production time, improving adaptability, and incorporating functionality. To this end, we propose a method of designing and producing 3D printed assistive devices and we also present an example of an assistive device, done in the 3D Printing Center for Health, as well as its impact on the patient's daily life. With this device, the patient became able to play the guitar and hold a knife, thus helping on these two activities.
Assessment of the Impact of Home-Based Hospitalization on Health Outcomes: An Observational Study Pedro Correia Azevedo, Cátia Rei, Rui Grande, Mariana Saraiva, Federico Guede-Fernández, et al. Acta Medica Portuguesa, 2024 Introduction: In Portugal, evidence of clinical outcomes within home-based hospitalization programs remains limited. Despite the adoption of homebased hospitalization services, it is still unclear whether these services represent an effective way to manage patients compared with inpatient hospital care. Therefore, the aim of this study was to evaluate the outcomes of home-based hospitalization compared with conventional hospitalization in a group of patients with a primary diagnosis of infectious, cardiovascular, oncological, or ‘other’ diseases.Methods: An observational retrospective study using anonymized administrative data to investigate the outcomes of home-based hospitalization (n = 209) and conventional hospitalization (n = 192) for 401 Portuguese patients admitted to CUF hospitals (Tejo, Cascais, Sintra, Descobertas, and the Unidade de Hospitalização Domiciliária CUF Lisboa). Data on demographics and clinical outcomes, including Barthel index, Braden scale, Morse scale, mortality, and length of hospital stay, were collected. The statistical analysis included comparison tests and logistic regression.Results: The study found no statistically significant differences between patients’ admission and discharge for the Barthel index, Braden scale, and Morse scale scores, for both conventional and home-based hospitalizations. In addition, no statistically significant differences were found in the length of stay between conventional and home-based hospitalization, although patients diagnosed with infectious diseases had a longer stay than patients with other conditions. Although the mortality rate was higher in home-based hospitalization compared to conventional hospitalization, the mortality risk index (higher in home-based hospitalization) assessed at admission was a more important predictor of death than the type of hospitalization.Conclusion: The study found that there were no significant differences in outcomes between conventional and home-based hospitalization. Home-based hospitalization was found to be a valuable aspect of patient- and family-centered care. However, it is noteworthy that patients with infectious diseases experienced longer hospital stays.
Effectiveness of the KC@H programme compared with clinic-based rehabilitation in patients recovering from ACL reconstruction: a study protocol for a single-centre, two-arm, single-blinded, randomised controlled superiority trial Joana Alegrete, Nuno Batalha, Orlando Fernandes, Jose Alberto Parraca, Ana Maria Rodrigues, et al. BMJ Open Sport and Exercise Medicine, 2024 Patients who cannot fully comply with conventional clinic-based rehabilitation (CR) sessions after ACL reconstruction (ACLR) may find additional internet-based sessions beneficial. These remote sessions include therapeutic exercises that can be done at home, potentially extending the reach of rehabilitation services to underserved areas, prolonging the duration of care and providing improved supervision. The study’s main purpose is to determine if the Knee Care at Home (KC@H) programme is more effective than conventional CR alone in improving patient-reported, clinician-reported and physical functional performance outcome measures after ACLR. Additionally, the trial assesses the significance of changes in outcome measures for clinical practice.This protocol outlines a randomised controlled trial for postoperative recovery following ACLR. Adult participants of both sexes who meet specific criteria will be randomly assigned to either the CR group or the KC@H group. Only the latter group will receive internet-based sessions of therapeutic exercises at home and CR sessions. A follow-up evaluation will be conducted for both groups 12 weeks after the intervention ends.The trial protocol was approved by the Ethics Committee of the Universidade de Évora and complies with the Code of Ethics of the World Medical Association. All recordings will be stored on a secure server with limited access and deleted as soon as they are no longer needed.The KC@H programme is expected to be superior to conventional CR for patients recovering from ACLR across multiple outcome measures. Also, the programme has the potential to promote superior recovery and extend the reach and duration of care.Trial registration number:NCT05828355.
Modular Framework for Comparative Analysis of EMG Detection Methods: Application to Wearable Interfaces for Persons with Motor Neuron Diseases C Amante, C Consolado, G Pires, AR Londral, C Quaresma 2026
Integrating Prevention Into Health Systems: A Prevention-first Framework for Noncommunicable Diseases W Mekniran, J Robert, J Mair, K Gand, H Schlieter, O Castro, M Nißen, ... 2025
Mapping methodologies for economic evaluation of digital health technologies: a scoping review AR Santos, F von Hafe, F Sampaio, AR Londral, J Perelman Value in Health , 2025 2025 Citations: 3
Mapping methodologies for economic assessment of digital health technologies AR Santos, F Sampaio, AR Londral, J Perelman 2025
Mapping methodologies for economic assessment of digital health technologies: a scoping review protocol AR Santos, F Sampaio, AR Londral, J Perelman BMJ open 15 (7), e099933 , 2025 2025 Citations: 4
User-Centered and Technical Requirements for Myoelectric Pediatric Arm Prosthesis Design: A Preliminary Study A Oliveira, A Londral, A Giordano, B Soares, C Quaresma Doctoral Conference on Computing, Electrical and Industrial Systems, 183-197 , 2025 2025
Multi-activity 3D printed assistive technology in children: a case study J Silva, M Silva, B Soares, C Quintão, AR Londral, C Quaresma Assistive Technology 37 (3), 159-164 , 2025 2025 Citations: 11
Features of Remote Patient Monitoring Systems That Implement Integrated Care: A Perspective Aligned With Current Challenges for Digital Health Technologies: Comment on" Towards … A Londral International Journal of Health Policy and Management 14, 8724 , 2025 2025 Citations: 1
Features of Remote Patient Monitoring Systems That Implement Integrated Care A Londral 2025
Mapping methodologies for economic evaluation of digital health technologies AR Santos, F von Hafe, F Sampaio, AR Londral, J Perelman 2025
A conversational agent for enhanced Self-Management after cardiothoracic surgery A Martins, LV Lapão, IL Nunes, AP Giordano, H Semedo, C Vital, R Silva, ... International Journal of Medical Informatics 192, 105640 , 2024 2024 Citations: 4
Enhancing postoperative anticoagulation therapy with remote patient monitoring: A pilot crossover trial study to evaluate portable coagulometers and chatbots in cardiac surgery … F Guede-Fernández, T Silva Pinto, H Semedo, C Vital, P Coelho, ... Digital Health 10, 20552076241269515 , 2024 2024 Citations: 8
Assessment of the Impact of Home-Based Hospitalization on Health Outcomes: An Observational Study PC Azevedo, C Rei, R Grande, M Saraiva, F Guede-Fernández, E Oliosi, ... Acta Médica Portuguesa 37 (6), 445-454 , 2024 2024 Citations: 1
Unlocking human-like conversations: Scoping review of automation techniques for personalized healthcare interventions using conversational agents A Martins, A Londral, IL Nunes, LV Lapão International journal of medical informatics 185, 105385 , 2024 2024 Citations: 57
Multi-activity 3D printed assistive technology in children J Silva, M Silva, B Soares, C Quintão, AR Londral, C Quaresma 2024
Effectiveness of the KC@ H programme compared with clinic-based rehabilitation in patients recovering from ACL reconstruction J Alegrete, N Batalha, O Fernandes, JA Parraca, AM Rodrigues, ... 2024
Effectiveness of the KC@ H programme compared with clinic-based rehabilitation in patients recovering from ACL reconstruction: a study protocol for a single-centre, two-arm … J Alegrete, N Batalha, O Fernandes, JA Parraca, AM Rodrigues, ... BMJ Open Sport & Exercise Medicine 10 (1) , 2024 2024 Citations: 1
Predicting post-discharge complications in cardiothoracic surgery: A clinical decision support system to optimize remote patient monitoring resources R Santos, B Ribeiro, I Sousa, J Santos, F Guede-Fernández, P Dias, ... International Journal of Medical Informatics 182, 105307 , 2024 2024 Citations: 18
Assessment of the Impact of Home-Based Hospitalization on Health Outcomes P Correia Azevedo, C Rei, R Grande, M Saraiva, F Guede-Fernández, ... 2024
Predicting post-discharge complications in cardiothoracic surgery R Santos, B Ribeiro, I Sousa, J Santos, F Guede-Fernández, P Dias, ... 2024
MOST CITED SCHOLAR PUBLICATIONS
Quality of life in amyotrophic lateral sclerosis patients and caregivers: impact of assistive communication from early stages A Londral, A Pinto, S Pinto, L Azevedo, M De Carvalho Muscle & nerve 52 (6), 933-941 , 2015 2015 Citations: 117
Scale-up of digital innovations in health care: expert commentary on enablers and barriers H Schlieter, LA Marsch, D Whitehouse, L Otto, AR Londral, GW Teepe, ... Journal of medical Internet research 24 (3), e24582 , 2022 2022 Citations: 106
Unlocking human-like conversations: Scoping review of automation techniques for personalized healthcare interventions using conversational agents A Martins, A Londral, IL Nunes, LV Lapão International journal of medical informatics 185, 105385 , 2024 2024 Citations: 57
Tecnologias de Apoio para Pessoas com Deficiência P Encarnação, L Azevedo, A Londral 2016 Citations: 36
Developing and validating high-value patient digital follow-up services: a pilot study in cardiac surgery A Londral, S Azevedo, P Dias, C Ramos, J Santos, F Martins, R Silva, ... BMC health services research 22 (1), 680 , 2022 2022 Citations: 35
Machine learning approaches for the frailty screening: a narrative review E Oliosi, F Guede-Fernández, A Londral International Journal of Environmental Research and Public Health 19 (14), 8825 , 2022 2022 Citations: 31
Monitoring amyotrophic lateral sclerosis by biomechanical modeling of speech production P Gómez-Vilda, ARM Londral, V Rodellar-Biarge, JM Ferrández-Vicente, ... Neurocomputing 151, 130-138 , 2015 2015 Citations: 29
Markers for upper limb dysfunction in Amyotrophic Lateral Sclerosis using analysis of typing activity A Londral, S Pinto, M de Carvalho Clinical Neurophysiology 127 (1), 925-931 , 2016 2016 Citations: 23
Domains and methods used to assess home telemonitoring scalability: systematic review S Azevedo, TC Rodrigues, AR Londral JMIR mHealth and uHealth 9 (8), e29381 , 2021 2021 Citations: 19
Predicting post-discharge complications in cardiothoracic surgery: A clinical decision support system to optimize remote patient monitoring resources R Santos, B Ribeiro, I Sousa, J Santos, F Guede-Fernández, P Dias, ... International Journal of Medical Informatics 182, 105307 , 2024 2024 Citations: 18
Which outcomes are most important to measure in patients with COVID-19 and how and when should these be measured? Development of an international standard set of outcomes … WH Seligman, L Fialho, N Sillett, C Nielsen, FM Baloch, P Collis, ... BMJ open 11 (11), e051065 , 2021 2021 Citations: 18
Image analysis system for early detection of cardiothoracic surgery wound alterations based on artificial intelligence models C Pereira, F Guede-Fernández, R Vigário, P Coelho, J Fragata, A Londral Applied Sciences 13 (4), 2120 , 2023 2023 Citations: 17
Application of the lognormal model to the vocal tract movement to detect neurological diseases in voice C Carmona-Duarte, R Plamondon, P Gómez-Vilda, MA Ferrer, JB Alonso, ... International Conference on Innovation in Medicine and Healthcare, 25-35 , 2016 2016 Citations: 15
Assistive technologies for communication empower patients with ALS to generate and self-report health data A Londral Frontiers in Neurology 13, 867567 , 2022 2022 Citations: 14
Scaling-up digital follow-up care services: collaborative development and implementation of remote patient monitoring pilot initiatives to increase access to follow-up care S Azevedo, F Guede-Fernández, F von Hafe, P Dias, I Lopes, N Cardoso, ... Frontiers in Digital Health 4, 1006447 , 2022 2022 Citations: 12
Towards improving the usability of electromyographic interfaces H Silva, R Scherer, J Sousa, A Londral Converging clinical and engineering research on neurorehabilitation, 437-441 , 2013 2013 Citations: 12
Multi-activity 3D printed assistive technology in children: a case study J Silva, M Silva, B Soares, C Quintão, AR Londral, C Quaresma Assistive Technology 37 (3), 159-164 , 2025 2025 Citations: 11
Remote Patient Monitoring Systems based on Conversational Agents for Health Data Collection. P Dias, M Cardoso, F Guede-Fernandez, A Martins, A Londral HEALTHINF, 812-820 , 2022 2022 Citations: 11
Case management intervention of high users of the emergency department of a Portuguese hospital: a before-after design analysis S Gonçalves, F Von Hafe, F Martins, C Menino, MJ Guimarães, ... BMC Emergency Medicine 22 (1), 159 , 2022 2022 Citations: 9
Articulation acoustic kinematics in ALS speech PP Gomez, D Palacios, A Gomez, V Rodellar, AR Londral 2017 International Conference and Workshop on Bioinspired Intelligence … , 2017 2017 Citations: 9