Andrew Johan

EDUCATION

doctoral degree

RESEARCH, TEACHING, or OTHER INTERESTS

Food Science, Animal Science and Zoology, Multidisciplinary

Scopus Publications

Wireless stethoscope for auscultation of the heart and lungs in critically ill patients: a systematic review
Suhartini Ismail, Ricky Prawira, Andrew Johan, and Rifky Ismail
Universitas Airlangga
Background:Examining the heart and lungs is necessary for critically ill patients, as these individuals may have abnormalities with either or both of these organs. This review systematically determined how the auscultation of the heart and lungs using a wireless stethoscope affected the results. Methods: The research design used was a systematic review following preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Databases were searched using the search terms “auscultation," "critical patients," and "stethoscope wireless” and associated MeSH terms. The abstracts of the selected articles were examined independently by two researchers. A systematic search was conducted through several databases (Scopus, PubMed, JSTOR, and Springer-link), which were published from July 2012 to July 2022 .After reading the full content of the included studies, key themes and concepts were extracted and synthesized. Results: In total 142 articles were screened. Five articles met the inclusion criteria and were analyzed. The analysis revealed that wireless stethoscopes have increased sensitivity with indicators capable of diagnosing abnormal auscultation results in patients who have abnormal aucultation results on the gold standard. Three out of five studies suggested that the auscultation of the heart and lungs by wireless stethoscopes are more sensitive, while two other studies stated that wireless stethoscopes have the same sensitivity as manual acoustic stethoscopes. Conclusion: Based on this systematic review, a wireless stethoscope may be more sensitive than an acoustic one. Nevertheless, due to limited studies, a more well-controlled human study is warranted to be done.


Effects of peer support program on self-management in patients with end-stage renal disease undergoing hemodialysis
Fida' Husain, Henni Kusuma, and Andrew Johan
Institute of Research and Community Services Diponegoro University (LPPM UNDIP)
Background: End-stage renal disease (ESRD) patients undergoing hemodialysis require essential self-management to lifestyle changes to minimize the risk of complications, morbidity, and mortality. Efforts made to improve self-management of hemodialysis patients in previous studies were carried out by health workers that may not provide 'real' knowledge, while peer support programs carried out by patients as peers to share their experiences may provide more benefits.Purpose: The purpose of this study was to determine the effects of peer support programs on improving self-management in patients with ESRD undergoing hemodialysis.Methods: This study employed a quasi-experimental design and involved a total of 33 patients in the control group and 32 patients in the intervention group, who met the inclusion and exclusion criteria. The samples were recruited consecutively. The intervention of peer support programs was implemented through information support, emotional support, and mutual reciprocity in groups of 10-12 people to share experiences related to their self-management. The intervention was given for six sessions; each lasted for 30-45 minutes. The data were collected using the Indonesian version of the hemodialysis self-management instrument (HDSMI) and analyzed using a paired-sample t-test and independent-sample t-test.Results: The results showed that after the intervention, the mean score of self-management in the intervention group increased from 79.47±7.919 to 90.75±7.089, and in the control group, the mean increased from 81.88±8.291 to 82.12±7.692. After the implementation of peer support programs, there was a significant difference in the score of self-management between the intervention and control groups (p<0.001).Conclusion: Peer support programs gave an effect on increasing self-management in patients with ESRD undergoing hemodialysis. Peer support programs should be introduced early to ESRD patients undergoing hemodialysis so that they can learn about self-management from other patients.  


Ethanol extracts of ficus carica fruit and leaf normalize high serum lipid profile, TNF-α, and mda due to high fat diet in sprague dawley rat
Yhani Kartika Sukowati, Andrew Johan, and Retno Murwani
Enviro Research Publishers
Dyslipidemia is one of the main risk factors for cardiovascular disease (CVD). Ficus carica fruit and leaf contain polyphenolic compounds that can inhibit lipid peroxidation. Our research aimed to study the effect of ethanol extract of F. carica fruit (FcFrEx) and F. carica leaves ( FcLfEx ) on serum lipid (total cholesterol, LDLchol, HDLchol, Triglyceride (TG)), TNF-α, and MDA levels in rat fed a high-fat diet. This experiment was a randomized control group design with pre and post-test using 32 male Sprague Dawley rats. The animals were divided randomly into 4 groups: control diet ( C ), high-fat diet ( HF ), high-fat diet plus FcFrEx ( HF+FcFrEx ), and high-fat diet plus FcLfEx (HF + FcLfEx). The high-fat diet was given to HF, HF+FcFrEx, and HF+FcLfEx groups for 7 weeks and then FcFrEx and FcLfEx at 400mg/kg BW were given to HF+FcFrEx and FcLfEx groups respectively for 3 weeks. Data for each group at the end of 7 weeks feeding (pre-test) and the end of the experiment i.e 10 weeks (post-test) were analyzed using the paired t-test. Data among groups were analyzed by one-way ANOVA followed by LSD test. The results showed that FcFrEx and FcLfEx at 400mg/kg BW can reduce serum lipid, TNF-α, and MDA levels. In conclusion, both FcFrEx and FcLfEx can ameliorate dyslipidemia and oxidative stress due to a high-fat diet in Sprague Dawley rat.


The influence of sundanese zither (KACAPI) music therapy on anxiety levels in pre-cardiac catheterization patients
Kristiana Prasetya Handayani, Andrew Johan, and Chandra Bagus Ropyanto
Belitung Raya Foundation
Background: Patients who will have cardiac catheterization mostly experience anxiety. Unresolved anxiety may have a harmful effect such as increasing frequency of heart, breathing and blood pressure as well as risks of complication. Music is considered effective in reducing anxiety.
 Objective: This study aims to examine the effect of Sundanese zither (kacapi) music therapy on anxiety level in pre-cardiac catheterization patients.
 Methods: This was a quasi-experimental study. Fifty-six respondents were selected using consecutive sampling technique, which 28 respondents assigned in the experiment group and control group. Anxiety was measured using Hamilton Anxiety rating Scale (HARS). Data were analyzed using Wilcoxon and Mann-Whitney test.
 Results: The results showed an average decrease in anxiety value in the experiment group of 10.28, and in the control group of 3.25. Mann-Whitney test results obtained p value <0.001, which indicated that there was a significant difference of mean decrease between the experiment group and the control group.
 Conclusion: This study proves that the intervention of Sundanese kacapi music significantly decreasing anxiety levels (p <0.001) in pre-cardiac catheterization patients. It is suggested that Sundanese kacapi music can be used as an alternative therapy in the independent nursing interventions.   


Comparative effect of Tempe and soymilk on fasting blood glucose, insulin level and pancreatic beta cell expression (Study on streptozotocin-lnduced diabetic rats)
Siti Harnina Bintari, Natalia Desy Putriningt, Kartika Nugraheni, Nyoman Suci Widyastiti, Edi Dharmana, and Andrew Johan
Science Alert
Hyperglycemia in diabetes mellitus due to pancreatic beta cell destruction can cause the raising of free radicals production. Soy isoflavone-containing diets have been reported to be beneficial in diabetes because they show potential antioxidant and antihyperglycemia activities. This study was conducted to analyze the difference between isoflavone aglycones in tempe and isoflavone glycosides in soymilk on beta cell function including insulin secretion, fasting blood glucose (FBG) and insulin expression of pancreatic beta cells. Thirty sprague dawley (SD) male rats were randomly divided into 3 following groups: (K1) diabetic control (P1) tempe flour 1.8 g (P2) soymilk powder 1.35 g. The treatment were given everyday for 28 days via oral gavage. FBG was measured using the GOD-PAP method, serum insulin was measured using ELISA, insulin expression analysis was done by immunohistochemical. Value of p less than 5% (p<0.05) was considered statistically significant. Tempe flour significantly decrease FBG level better than soy milk and control group (p<0.01). Although both groups showed an increase in serum insulin level after intervention, there was no significant different between them (p = 0.639). There were also a significantly decrease in FBG level on soymilk group compared to control (p<0.01). The mean insulin expression on K1, P1 and P2 were 2.67±2.34, 6.17±1.47 and 6.83±1.17, respectively. The insulin expression of both groups were not significantly different (p = 0.405). It is concluded that tempe flour shows a better anti-diabetic activity than soymilk.