BHEEMREDDY ANUSHA
@sjgckurnool.edu.in
ASSISTANT PROFESSOR OF CHEMISTRY
SILVER JUBILEE GOVERNMENT COLLEGE(A), CLUSTER UNIVERSITY, KURNOOL, ANDHRA PRADESH, INDIA
EDUCATION
M.Sc, Ph.D
RESEARCH INTERESTS
TOTAL SYNTHESIS OF BIO-ACTIVE MOLECULES AND DEVELOPMENT OF NOVEL METHODOLOGIES
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Bheemreddy Anusha, Raveendra Babu Kothapalli, Miriyala Victor Prem Sagar, Bairla Surendra, and Ummareddy Venkata Subba Reddy
Informa UK Limited
Ummareddy Venkata Subba Reddy, Bheemreddy Anusha, Zubeda Begum, Chigusa Seki, Yuko Okuyama, Michio Tokiwa, Suguru Tokiwa, Mitsuhiro Takeshita, and Hiroto Nakano
MDPI AG
Chiral primary α-amino amides, consisting of an adjacent enamine bonding site (Bronsted base site), a hydrogen bonding site (Bronsted acid site), and flexible bulky substituent groups to modify the steric factor, are proving to be extremely valuable bifunctional organocatalysts for a wide range of asymmetric organic transformations. Primary α-amino amides are less expensive alternatives to other primary amino organocatalysts, such as chiral diamines and cinchona-alkaloid-derived primary amines, as they are easy to synthesize, air-stable, and allow for the incorporation of a variety of functional groups. In recent years, we have demonstrated the catalytic use of simple primary α-amino amides and their derivatives as organocatalysts for the aldol reaction, Strecker reaction, Michael tandem reaction, allylation of aldehydes, reduction of N-Aryl mines, opening of epoxides, hydrosilylation, asymmetric hydrogen transfer, and N-specific nitrosobenzene reaction with aldehydes.
Ummareddy Venkata Subba Reddy, Madhu Chennapuram, Kento Seki, Chigusa Seki, Bheemreddy Anusha, Eunsang Kwon, Yuko Okuyama, Koji Uwai, Michio Tokiwa, Mitsuhiro Takeshita,et al.
Wiley
Enantioselective crossed aldol reactions of isatin derivatives and acetaldehyde have been developed with a series of simple diamino alcohol catalysts to afford 3-substituted 3-hydroxyindolin-2-ones in high chemical yields (up to 95 %) and optical purities (up to 92 % ee). The synthetic potential of the present protocol has been demonstrated by concise, enantioselective, protecting-group-free, and transition metal-free total syntheses of antitumor and antiviral agents with the tryptanthrin architecture, that is, phaitanthrin B and cephalanthrin A, along with the biologically active indolidine alkaloids chimonamidine and donaxaridine as well as the formal synthesis of CPC-1. The highly enantioselective outcome of this catalytic crossed aldol reaction was evaluated by calculating the Gibbs free energies of the possible transition states.
Bheemreddy Anusha, Ummareddy V. Subba Reddy, Basireddy V. Subba Reddy, and Cirandur Suresh Reddy
SAGE Publications
A highly diastereoselective total synthesis of (+)-pseudohygroline (1) starting from D-proline is described using Wittig olefination and MacMillan-α-hydroxylation as key reactions. (+)-Pseudohygroline is an important molecule in alkaloid chemistry as it was prepared as part of the first chemical proof of the absolute stereochemistry of biosynthetically important (+)-hygroline (2) and (+)-hygrine (3).
Basireddy V. Subba Reddy, Bheemreddy Anusha, Ummareddy V. Subba Reddy, Jhillu S. Yadav, and Cirandur Suresh Reddy
Wiley
A short and efficient approach for the total synthesis of two novel cytotoxic hydroquinones, lanneaquinol (1) and (R)-2′-hydroxylanneaquinol (2) isolated from the organic extract of the plant Lannea welwitschii, has been developed. Enantioselective organocatalytic McMillan hydroxylation has been successfully utilized for the creation of the stereogenic center bearing the OH group of (R)-2′-hydroxylanneaquinol (2). The hydroquinone core was constructed through the alkylation of cyclohexane-1,4-dione with a corresponding aldehyde. Both hydroquinone natural products can be synthesized by a mere change in the synthetic strategy.
J.S. Yadav, U.V. Subba Reddy, B. Anusha, and B.V. Subba Reddy
Elsevier BV
J.S. Yadav, B.V. Subba Reddy, B. Anusha, U.V. Subba Reddy, and V.V. Bhadra Reddy
Elsevier BV