Ashok Kumar Jaiswal

Scopus Publications

Postmortem toxicology of alcohols: A cross-matrix study of ethanol and methanol in 150 cases from New Delhi, India
Neha Afaria, A.K. Jaiswal, Sudhir K. Gupta, Kulbhushan Prasad
Medicine Science and the Law, 2026
Ethanol is the most commonly abused drug worldwide, and excessive alcohol consumption is a major contributing factor in accidents and violent crimes. Methanol is a toxic alcohol and is less commonly detected but holds significant forensic relevance due to its potential for causing fatal poisoning. The study aims to detect the concentrations of ethanol and methanol in postmortem blood, vitreous humor, urine, and cerebrospinal fluid, and to create a database of the involvement of alcohol in postmortem cases. A total of 150 postmortem cases with different causes of death were enrolled for the study. Gas Chromatography-Headspace was employed for the quantitative determination of ethanol and methanol concentrations in the biological specimens. Out of 150 cases, 108 cases (72%) exhibited positive ethanol concentrations. The high prevalence of positive ethanol concentration, particularly in cases of road traffic accidents and hanging, indicated a significant amount of alcohol use prior to death and underscores the role of alcohol consumption in fatal incidents. Methanol was detected in only those cases that had a high ethanol concentration, which may be due to adulteration or contamination of methanol in the alcoholic beverages that the deceased consumed before death. The study highlighted that an alternative/ complementary specimen to the blood should be considered to assess the alcohol concentration and to differentiate antemortem ingestion of alcohol from postmortem formation. The toxicological analysis of alcohol is important in understanding consumption patterns and in developing protocols and policies for preventing such cases.
Detection of Ethanol and Methanol in Hand Sanitizers used in Public Places in Delhi during the COVID-19 Pandemic
Neha Afaria, Rohit Kanojia, A. K. Jaiswal, Sudhir K. Gupta, T. Millo
Toxicology International, 2024
Since the COVID-19 (coronavirus disease of 2019) pandemic, alcohol-based hand sanitizers are being used widely to prevent the transmission of corona virus. But a major concern is the adulteration of methanol in hand sanitizer. Cases of methanol poisoning increased drastically during the pandemic. This study was carried out to detect ethanol and methanol in hand sanitizers that are being sold and used in public places. The hand sanitizer samples for this study were collected from different public places in Delhi from June-August 2022. A total of 53 samples were collected and the samples were run on Gas Chromatography (GC-HS) for analysis of ethanol and methanol. Methanol was detected in 25 samples. During the COVID-19 pandemic, various cases of methanol poisoning due to consumption or chronic absorption of hand sanitizer have been reported all over the world. Methanol is a toxic alcohol and long-term dermal exposure to this toxic substance can cause severe health effects. During the pandemic, the increased demand of hand sanitizer resulted in uncontrolled manufacturing and sale of hand sanitizers. Data obtained from this study highlight the need to monitor the manufacturing and sale of alcoholbased hand sanitizer by the regulatory bodies and to raise awareness among the public about the toxic effects of methanol.
Development of a New Methodology for Extraction and Analysis of Pesticides, Drugs, Heavy Metals and Various Toxins from Viscera Samples
Rohit Kanojia, A. K. Jaiswal, Arkaja Goswami, Sunita Bhagat
Toxicology International, 2023
Viscera analysis plays a major and important role in forensics, Scientists use their own tried and tested methods to avoid excess time consumption and errors, to analyse the viscera samples for the presence of various illicit drugs, pesticides, heavy metals, or any other poisonous substances that may be the reason of death. In this article, the current scenario of viscera handling in forensic science laboratories in India is mentioned in detail with a step-by-step procedure. Tests for phosphine and various pesticides are performed in the stomach and small intestine. Drugs are extracted according to different procedures depending upon the affinity of the drug i.e., acidic, basic, or neutral. After that, Tests for drugs and other toxic substances are usually performed in blood, liver, spleen, and kidney. Blood usually comes in the third jar, and is tested for drugs, alcohol, and maybe for pesticides, phosphine and for any other suspected toxin. Viscera sample needs to be digested before the analysis of heavy metals. Any part of the viscera can be digested and tested for heavy metal. Usually, a mixture of all the viscera parts is digested and analysed. The techniques mentioned in this article are rigorously used in the chemistry and toxicology division in forensic laboratories in India.
Quantitative analysis of methanol in blood, urine, vitreous humor, and cerebrospinal fluid by using gas chromatography-head space in two suspected cases of methanol poisoning
Neha Afaria, A. K. Jaiswal, Venkatesh Janarthanan, Sudhir Kumar Gupta, T. Millo, G. Gokul
Proceedings of the Indian National Science Academy, 2023
ANALYSIS AND ANALYTICAL ASPECTS OF TOLUENE IN INHALANT OF ABUSE IN LIVING AND DEAD: A REVIEW
Journal of South India Medicolegal Association, 2023
Determination of Cd, Co, Cr, Ni and Pb metals in lipsticks samples by Flame atomic absorption spectrophotometry (FAAS)
A K Jaiswal, Raksha Chourase, Anita Yadav
Indian Journal of Forensic and Community Medicine, 2023
The study was conducted this work to analyze levels of toxic metals in lipsticks specifically sold in the Bhopal area. Acid digestion process was used to prepare the samples and to quantify the levels of heavy metals, including Cd, Co, Cr, Ni, and Pb Flame Atomic Absorption Spectrophotometry was used. Calibration curves were prepared with good linearity for accurate measurement of concentrations of these metals. All heavy metal observed were within the allowable limit. To assess the health risks, Average daily dose (ADD) and Hazard quotient (HQ) (Ingestion) for all the lipstick samples were calculated. Among these samples, three samples shows higher values among them one belonged to a branded category, while the remaining two were from the non-branded category. These particular Lipsticks samples exhibited higher HQ values (higher than 1), indicating a probable hazard linked of toxic-metals.
Parenteral Mercury Poisoning – An Interesting and Rare Case
Journal of Forensic Medicine Science and Law, 2022
COSMETIC PRODUCTS: A SOURCE OF HEAVY METAL TOXICITY IN HUMANS
Sneha Yadav, Lovlish Gupta, Monika Chauhan, Arvind Kumar Jain, Ashok Kumar Jaiswal
International Journal of Medical Toxicology and Legal Medicine, 2022
Cosmetic products have become one of the major essentialities of our usual lives which are subsequently used by people of variable age groups. Some of the majorly used products include facial and body creams, lipsticks, nail paints, lip glosses, mascaras, etc. These products generally contain some heavy metals and chemicals as preservatives to ward off microbial expansion. However, these preservatives are proven to be most toxic for the cells where applications of these products are maximum such as epithelial cells of skin, corneal and conjunctival cells of eyes, etc. Though cosmetic products have various advantages, the dark side of these products indicates the total dependency of humans due to the methodical use of such products. Various researchers have estimated that some toxic heavy metals such as arsenic (As), lead (Pb), nickel (Ni), cadmium (Cd), Cobalt (Co), and chromium (Cr) are found in varying concentrations in different cosmetic products especially the products which are applied directly on the skin, such as eyeliner, lip moisturizer, lipstick, facial creams, etc. Sometimes the concentration of the above heavy metals exceeds the permissible limits set by WHO (World Health Organisation). Heavy metals are known to have beneficiary as well as toxic effects on humans, animals as well as environment. The presence of these heavy metals in cosmetics is widely harmful as they are absorbed via skin in heavy concentrations which causes mutations that further leads to various 100s of hazardous disease like mental retardation, skin cancer, respiratory disorders, etc. Therefore, various techniques are approached to assess the presence of these heavy metals in cosmetic products. Some of these are atomic absorption spectrometer (AAS), laser-induced breakdown spectroscopy (LIBS), Inductively coupled plasma mass spectroscopy (ICP-MS), etc. Thus, the present review article focused on the problems related to the presence of heavy metals in cosmetics, including their sources, concentrations, and law regulations as well as Toxic effects on human health.
ESTIMATION OF ALUMINIUM LEVELS IN BLOOD, LIVERAND STOMACH CONTENTS USINGICP-AES: ACROSS-SECTIONAL AUTOPSY BASED STUDY
Anita Yadav, Adarsh Kumar, Amita Srivastava, AK Jaiswal, SK Gupta
Journal of Forensic Medicine and Toxicology, 2022
Screening/spot/colour test of anti-arrhythmic drugs
Ashok Kumar Jaiswal, Kamna Sharma, S Lukose, Madhuri Gupta
Indian Journal of Forensic and Community Medicine, 2021
Anti-arrhythmic drugs are those drugs that are used to suppress abnormal rhythms of the heart. It acts as restoration of normal rhythms of the heart and conduction of the heart. These drugs directly or indirectly alter the membrane ion conductance, which in turn alters the physical characteristics of cardiac action potentials. In India, Forensic Science Laboratories run by Government under the Home ministry usually carry out this. The samples must be analyzed by the forensic toxicologist/chemists/scientist. This article deals with the screening/spot test for anti-arrhythmic drugs. An attempts has been made for screening/spot/colour test of anti-arrhythmic drugs in a stepwise manner, which can be of handy reference for the forensic toxicologist/scientist/chemist.
Voltammetric approach of arsenic (total) determination in blood using sctrace gold electrode
Toxicology International, 2020
Biochemical findings in sudden unexpected death in epilepsy: Hospital based case-control study
Shyam Kishore, Sudhir Kumar Gupta, Sudheer Kumar Arava, Asit Ranjan Mridha, Ashok Kumar Jaiswal, Asit Kumar Sikary, Deepak Ramkumar Bharti, Chittaranjan Behera
Journal of Forensic and Legal Medicine, 2020
Potency test of a rape accused in India – Rationale, problems and suggestions in light of the Criminal Law (Amendment) Act, 2013
Md Shadab Raheel, Abhishek Yadav, Shashank Pooniya, Sudhir Kumar Gupta, A.K. Jaiswal
Egyptian Journal of Forensic Sciences, 2016
Accidental carbon monoxide poisoning during yagya for faith healing - A case report
Journal of the Indian Medical Association, 2013
Thallium poisoning: Analytical aspects with brief overview
Journal of South India Medicolegal Association, 2012
Analysis of finit in urine sample using thin layer chromatography.
Journal of Environmental Science Engineering, 2012
Voltammetric/Polarography trace metal analyzer and its Forensic Application-A review
Journal of Forensic Medicine and Toxicology, 2012
Identification of human beings by morphological characterization of their teeth in Forensic cases
Journal of Forensic Medicine and Toxicology, 2012
Detection of monocrotophos by thin layer Chromatography from urine sample- A case report
Journal of South India Medicolegal Association, 2012
Screening/spot test of tranquilisers
International Journal of Medical Toxicology and Legal Medicine, 2011
A complete analysis of postmortem materials received in forensic toxicology laboratory
Journal of Forensic Medicine and Toxicology, 2011
A complete analysis of postmortem materials received in forensic toxicology laboratory
International Journal of Medical Toxicology and Legal Medicine, 2011
Molecular mechanism of aluminium & zinc phosphide toxicity: Focus on analytical techniques used for their forensic analysis
International Journal of Medical Toxicology and Legal Medicine, 2011
Microwave digestor and its forensic application - A review
Journal of Forensic Medicine and Toxicology, 2011
Screening/spot/colour test of alkaloids
International Journal of Medical Toxicology and Legal Medicine, 2011
Emerging issues of concern to the Indian forensic toxicologists with special reference to drugs of abuse
International Journal of Medical Toxicology and Legal Medicine, 2010
Screening/spot test of antibiotics
International Journal of Medical Toxicology and Legal Medicine, 2010
Screening/spot test of acids & alkalis (bases)
International Journal of Medical Toxicology and Legal Medicine, 2010
Atomic absorption spectrometry - A review
Journal of Forensic Medicine and Toxicology, 2010
Screening/spot test for drug of abuse
International Journal of Medical Toxicology and Legal Medicine, 2010
Toxicology manual series article - X: Screening/spot test for pesticides/insecticides
International Journal of Medical Toxicology and Legal Medicine, 2010
Breath alcohol analyzer and its forensic applications
Journal of Forensic Medicine and Toxicology, 2010
Screening/spot test for plant poisons
International Journal of Medical Toxicology and Legal Medicine, 2009
Screening/spot test for toxic anions
International Journal of Medical Toxicology and Legal Medicine, 2009
Forensic applications of UV-visible spectrophtometer - A review
Journal of Forensic Medicine and Toxicology, 2009
Screening/spot test for metallic poisions
International Journal of Medical Toxicology and Legal Medicine, 2009
Screening/spot test for volatile poisions
International Journal of Medical Toxicology and Legal Medicine, 2009
Thin layer chromatography (TLC) an important tool for forensic scientists toxicology - A review
Journal of Forensic Medicine and Toxicology, 2009
Development of new solvent systems for the extraction and identification of fenvalerate poison from blood
Proceedings of the Indian National Science Academy, 2008
Development of new solvent systems for the analysis of chlorpyrifos poison extracted from blood
Proceedings of the Indian National Science Academy, 2008
Extraction and isolation methods for miscellaneous poisons from biological samples
International Journal of Medical Toxicology and Legal Medicine, 2008
High Performance Liquid Chromatography (HPLC) and its forensic applications - A review
Journal of Forensic Medicine and Toxicology, 2008
Extraction and isolation methods for miscellaneous poisons from biological samples
International Journal of Medical Toxicology and Legal Medicine, 2008
Do's and Don'ts for sophisticated analytical instruments Vol - III
Journal of Forensic Medicine and Toxicology, 2008
Extraction, isolation and clean -UP methods for barbiturates & tranquillizers from biological material
International Journal of Medical Toxicology and Legal Medicine, 2007
Extraction/isolation methods for metallic, volatile and cyanide poisons from biological samples
International Journal of Medical Toxicology and Legal Medicine, 2007
Determination of antimony in forensic samples by atomic absorption spectrophotometer
International Journal of Medical Toxicology and Legal Medicine, 2007
Planning and designing of modern forensic toxicology laboratory
Journal of Forensic Medicine and Toxicology, 2007
Do's and dont's for different personnels involved in crime investigation of poisoning deaths in India
Journal of Forensic Medicine and Toxicology, 2007
Alcohol content in country made liquors: Forensic consideration
Medico Legal Update, 2007
Do's and dont's for sophisticated analytical instruments Vol-II
International Journal of Medical Toxicology and Legal Medicine, 2006
Extraction, isolation and clean-up methods for pesticides/insecticides & alkaloids from biological material. Part-I
International Journal of Medical Toxicology and Legal Medicine, 2006
Gas chromatography and its forensic applications - A review
International Journal of Medical Toxicology and Legal Medicine, 2006
Determination of Barium in forensic samples by atomic absorption spectrophotometer
Journal of Forensic Medicine and Toxicology, 2006
Determination of lead in forensic samples by atomic absorption spectrophotometer
Medico Legal Update, 2006

Ashok Kumar Jaiswal

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Scopus Publications