Asmaa Tahseen Uthman

@gmu.ac.ae

Diagnostic & surgical dental sciences
Gulf Medical University

EDUCATION

Master of Science in Oral & Maxillofacial radiology

RESEARCH, TEACHING, or OTHER INTERESTS

Dentistry, General Dentistry, Periodontics

25

Scopus Publications

Scopus Publications

  • Tunable theranostics: innovative strategies in combating oral cancer
    Asmaa Uthman, Noor AL-Rawi, Musab Hamed Saeed, Bassem Eid, and Natheer H. Al-Rawi

    PeerJ
    Objective This study aims to assess and compare the potential of advanced nano/micro delivery systems, including quantum dots, carbon nanotubes, magnetic nanoparticles, dendrimers, and microneedles, as theranostic platforms for oral cancer. Furthermore, we seek to evaluate their respective advantages and disadvantages over the past decade. Materials and Methods A comprehensive literature search was performed using Google Scholar and PubMed, with a focus on articles published between 2013 and 2023. Search queries included the specific advanced delivery system as the primary term, followed by oral cancer as the secondary term (e.g., “quantum dots AND oral cancer,” etc.). Results The advanced delivery platforms exhibited notable diagnostic and therapeutic advantages when compared to conventional techniques or control groups. These benefits encompassed improved tumor detection and visualization, enhanced precision in targeting tumors with reduced harm to neighboring tissues, and improved drug solubility and distribution, leading to enhanced drug absorption and tumor uptake. Conclusion The findings suggest that advanced nano/micro delivery platforms hold promise for addressing numerous challenges associated with chemotherapy. By enabling precise targeting of cancerous cells, these platforms have the potential to mitigate adverse effects on surrounding healthy tissues, thus encouraging the development of innovative diagnostic and therapeutic strategies for oral cancer.

  • Comparative Analysis of Manual Dexterity of Dental Students at Ajman University following One Academic Year of Preclinical Training Sessions: A Longitudinal Cohort Study
    Musab Saeed, Mohammed B.Q. Alfarra, Mawada Hassan Abdelmagied, Karrar Hadi, Tareq Aljafarawi, Noor Al-Rawi, Asmaa T. Uthman, Salem Abu Fanas, and Natheer H. Al Rawi

    Georg Thieme Verlag KG
    Abstract Objectives Dental students must complete two stages of training, namely, preclinical training on phantom head models and clinical training on actual patients to acquire the practical skills required by their Bachelor of Dental Surgery program.Our objectives are to evaluate the level of improvement of the manual skills obtained by third-year dental students after one full academic year of preclinical training courses using dexterity tests under direct and indirect vision and to compare the improvement among male and female dental students under the same conditions. Materials and Methods A total of 72 preclinical students participated in our cohort trial, each of whom was assigned a random identification number that was only known to the researchers. After the beginning of the academic year, the experiment was performed under identical conditions for both the O'Connor Tweezer Dexterity Test and the Purdue Pegboard Test. The examinations were conducted at two distinct times: T0 before phantom laboratory training (the beginning of preclinical sessions) and T1 after phantom laboratory training (9 months after T0). Statistical Analysis Signed-rank test of Wilcoxon over two separate periods (T0 and T1), comparisons were made between the direct and indirect visual dexterity test scores. In addition, the Mann–Whitney U test was used to compare results across gender. The statistical significance (p-value) was set at below 0.05 with a confidence level of 95%. Results A statistically significant difference was detected between the T0 and T1 assessments on the Purdue Pegboard Test and the O'Connor Tweezer Dexterity Test for all selected dentistry students in both direct and indirect conditions (p < 0.001). Conclusion Further investigation in other dental departments or schools, particularly those with different entry standards, is required prior to making a definitive conclusion about the use of these dexterity assessments as predictors of prospective dental students' performance.

  • Anatomical landscape of oral squamous cell carcinoma: A single cancer center study in UAE
    Natheer H. Al-Rawi, Ibrahim Y. Hachim, Mahmood Y. Hachim, Abdulrahman Salmeh, Asmaa T. Uthman, and Hesham Marei

    Elsevier BV

  • Morphometric analysis of odontoid process among Arab population: a retrospective cone beam CT study
    Asmaa Uthman, Basheer Salman, Hawraa Shams Aldeen, Hesham Marei, Sura F. Al-Bayati, and Natheer H. Al-Rawi

    PeerJ
    Objective This study aims to evaluate the feasibility of using cone beam computed tomography (CBCT) scans to assess the odontoid process diameter in the Arab population and to determine whether one or two cortical screws can be used for treating odontoid fractures. Methods The odontoid process of 142 individuals aged 12–75 years, including 72 males (mean age: 35.5) and 70 females (mean age: 36.2), were analyzed using CBCT scans. The sagittal and coronal CBCT views were used to evaluate the antero-posterior (AP) and transverse diameters of the odontoid process. Results Males had substantially bigger transverse and AP diameters of the odontoid process than females (p < 0.05 & P < 0.01 respectively). Among the sample, 97 individuals (67.4%) had external transverse diameter (METD) of less than 9 mm which is slightly bigger than that of Indians and 48 individuals (31.83%) had enough room for two 3.5 mm or two 2.7 mm screws as their METD was more than 9 mm like that of Greek and Turkish. Age had no significant impact on the morphometric measurements of the odontoid process. Conclusion More than sixty percent of the sample had METDs of less than 9 millimeters, indicating that a single 4.5-mm Herbert screw may be suggested for fixing fractured odontoid processes in the Arab population.

  • Association between maternal periodontitis, acute-phase reactants and preterm birth
    Natheer H Al‐Rawi, Nada K Imran, Ali A Abdulkareem, Abeer M Abdulsattar, and Asmaa T Uthman

    Oral Diseases Wiley

  • Characteristics of Suture Materials Used in Oral Surgery: Systematic Review
    Abdullah Faris, Lian Khalid, Mohammed Hashim, Sara Yaghi, Taif Magde, Ward Bouresly, Zaid Hamdoon, Asmaa T. Uthman, Hesham Marei, and Natheer Al-Rawi

    Elsevier BV

  • Depression, Anxiety and Stress Among Dentists During COVID-19 Lockdown
    Natheer H. Al-Rawi, Asmaa T. Uthman, Musab Saeed, Ali A. Abdulkareem, Sura Al Bayati, and Ahmed Al Nuaimi

    Open Dentistry Journal Bentham Science Publishers Ltd.
    Introduction: The objective of this study was to investigate the levels of depression, anxiety, and stress among dentists during covid-19 lockdown and to investigate the relationship between stress and each mental health state. Methods: A cross-sectional survey on 269 dentists was conducted using DASS-21 and PHQ-9 questionnaires. Bivariate and multivariate models were constructed and the odds ratio (OR) was calculated to assess the strength of the association between an independent categorical variable and the outcome. Results and Discussion: Being unsatisfied with the job was associated with a statistically significant increase in DASS-21 score by an average of 5.9 points after adjusting for the possible confounding effect of the other independent variables included in the model. For each extra 10 years of clinical experience, there is a statistically significant reduction in DASS-21 score by an average of 1.3 points compared after adjusting for the possible confounding effect of the other independent variables included in the model. Conclusion: Stress, depression, and anxiety were prevalent during the pandemic among dentists. These psychological domains were modulated by several factors including marital status, gender, years of clinical experience, and degree of job satisfaction.

  • Accuracy of Linear Measurements of Maxillary Sinus Dimensions in Gender Identification Using Machine Learning
    Abdullah Al-Amodi, Ibrahim Kamel, Natheer H Al-Rawi, AsmaaT Uthman, and Shishir Shetty

    IEEE
    Linear measurements of the maxillary sinus are useful for gender prediction. This variation could be used for forensic identification purposes in mass disasters. The study aims to evaluate the accuracy of the artificial intelligence-based technique in gender prediction using linear measurements of maxillary sinus from Cone Beam Computed Tomography CBCT scans.

  • Accuracy of Sphenoidal Sinus Morphometry in Forensic Identification Using Cone Beam Computed Tomography


  • COVID-19: Unraveling 10 Most Significant Answers about The Current Pandemic


  • Teeth Whitening and Antibacterial Effects of Juglans regia Bark: A Preliminary Study
    Riham Al-Rawi, Yusra Bashir, Aseel Mustafa, Mennatalla Omar, Noor AL-Rawi, Musab Saeed, Asmaa Uthman, and Natheer H. Al-Rawi

    Hindawi Limited
    Objectives. Natural folk medicines with antimicrobial effects have been under investigation during the past decades. The aim of this study was to evaluate the teeth whitening and antimicrobial effects of ethanol extract of Persian walnut “Juglans regia” barks. Materials and Methods. Minimum inhibitory concentration (MIC) was determined using a broth microdilution assay which was conducted through a 2-fold serial dilution method, and a whitening experiment was done in vitro on extracted teeth, with a pH test being performed on 2-fold dilutions of the ethanol extract. Result. It was found that the MIC for Enterobacter and E. coli and Staphylococcus and Pseudomonas was found to be 5 mg/ml and 2.5 mg/ml, respectively. Both dilutions were found to be acidic, and the extract of Juglans regia bark also demonstrated the ability of teeth whitening. Conclusion. This study supports the use of Juglans regia bark as a natural product in dentistry because of the confirmed antimicrobial ability as well as its whitening effect. Clinical Relevance. Herb extract might be incorporated within commercially available kinds of toothpaste to enhance its whitening and antimicrobial effects.

  • Neutrophil Extracellular Traps in Coronavirus Infection: Interaction Network Analysis
    Abdelmalek Bouzid, A. Uthman, N. Al-Rawi and N. Al-Rawi


    Background: This study objective was to investigate, through interaction network analysis, the target genes involved in the pathogenesis of neutrophil extracellular traps (NETs) in coronavirus infection. Method: Genes participating in the pathogenesis of NETs were recognized in GeneCards database. Gene list was extended, and the gene interactions network was mapped using the STRING software. Weighted number of links (WNL) were calculated to identify “leader genes”. Total interactions score (TIS) was calculated using all interaction data generated by the STRING database. The ontological analyses were also performed using BinGO plugin and Cytoscape software. Results: Seven sets of genes (IL6, TNF, CRP, CXCL8, IL-1s, IL17A and IL-1a) were identified in the GeneCards database. The suggested leader genes from the results of interaction scores were IL-6, TNF, IL-1s and CXCL-8 with the highest adjusted WNL values. However, the most influential genes in the network were IL-17 and CRP, with WNL/TIS ratios of 0.988 and 0.986, respectively. Conclusion: The above results might suggest the participation of potential genes to facilitate the understanding of complex pathogenesis mechanisms of coronavirus infection. The clinical course of SARS-CoV-2 infection can be modulated by evaluating the activity of NETosis which represents a promising therapeutic target for the COVID-19.

  • Magnetism in drug delivery: The marvels of iron oxides and substituted ferrites nanoparticles
    Noor Natheer Al-Rawi, Basma Azad Anwer, Natheer Hashim Al-Rawi, Asmaa Tahseen Uthman, and Iman Saad Ahmed

    Elsevier BV

  • Pre-exposure prophylaxis for COVID-19 infection: Current concepts and strategies
    A. Uthman, N. Al-Rawi and N. Al-Rawi


    The current pandemic of COVID-19 disease has spread, in a matter of a few months to nearly 200 countries, and the absence of a treatment has put the world in jeopardy. To date, more than 42 million people worldwide have been infected with severe acute respiratory distress syndrome coronavirus 2 (SARS CoV-2) and nearly 1.25 million have died from COVID-19 Pandemic. Many countries moved toward resuming work activities and social interaction to rescue economy. This makes population continue suffering severe losses in the absence of strict prophylaxis strategy against this pandemic. It is well known that prevention is better than cure, therefore, we plan to display the current strategies that should be implemented prior to exposure to infection and underlines its effectiveness in containing the infection. Repurposed vaccines and SARS-CoV-2 specific vaccines are also mentioned, to keep up with the most recent updates that are being carried out. How to Cite this Article Pubmed Style Uthman AT, Al-Rawi NN, Al-Rawi N. Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies. SRP. 2020; 11(9): 860-865. doi:10.31838/srp.2020.9.124 Web Style Uthman AT, Al-Rawi NN, Al-Rawi N. Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies. http://www.sysrevpharm.org/?mno=22175 [Access: March 31, 2021]. doi:10.31838/srp.2020.9.124 AMA (American Medical Association) Style Uthman AT, Al-Rawi NN, Al-Rawi N. Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies. SRP. 2020; 11(9): 860-865. doi:10.31838/srp.2020.9.124 Vancouver/ICMJE Style Uthman AT, Al-Rawi NN, Al-Rawi N. Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies. SRP. (2020), [cited March 31, 2021]; 11(9): 860-865. doi:10.31838/srp.2020.9.124 Harvard Style Uthman, A. T., Al-Rawi, . N. N. & Al-Rawi, . N. (2020) Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies. SRP, 11 (9), 860-865. doi:10.31838/srp.2020.9.124 Turabian Style Uthman, Asmaa T, Noor N Al-Rawi, and Natheer Al-Rawi. 2020. Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies. Systematic Reviews in Pharmacy, 11 (9), 860-865. doi:10.31838/srp.2020.9.124 Chicago Style Uthman, Asmaa T, Noor N Al-Rawi, and Natheer Al-Rawi. "Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies." Systematic Reviews in Pharmacy 11 (2020), 860-865. doi:10.31838/srp.2020.9.124 MLA (The Modern Language Association) Style Uthman, Asmaa T, Noor N Al-Rawi, and Natheer Al-Rawi. "Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies." Systematic Reviews in Pharmacy 11.9 (2020), 860-865. Print. doi:10.31838/srp.2020.9.124 APA (American Psychological Association) Style Uthman, A. T., Al-Rawi, . N. N. & Al-Rawi, . N. (2020) Pre-Exposure Prophylaxis for COVID-19 Infection: Current Concepts and Strategies. Systematic Reviews in Pharmacy, 11 (9), 860-865. doi:10.31838/srp.2020.9.124

  • Concha bullosa, nasal septal deviation, and their impacts on maxillary sinus volume among Emirati people: A cone-beam computed tomography study
    Natheer H Al-Rawi, Asmaa T Uthman, Elaf Abdulhameed, Ahmed S Al Nuaimi, and Zahra Seraj

    Korean Academy of Oral and Maxillofacial Radiology
    Purpose To determine the prevalence of concha bullosa (CB) and nasal septal deviation (NSD) and their impact on maxillary sinus volume (MSV). Materials and Methods Cone-beam computed tomographic (CBCT) images of 106 Emirati people were used in this study. The direction and angle of septal deviation were calculated. The presence of CB, which could be unilateral, contralateral, or bilateral in relation to the direction of NSD, was also recorded. MSV was measured using reconstructed Digital Imaging and Communication in Medicine images on Dolphin 3D imaging software version 11.8 premium (Dolphin Imaging, Chatsworth, CA, USA). P values <0.05 were considered to indicate statistical significance. Results CB was detected in 37.7% of the sample; 20.7% of the sample showed single unilateral CB and 16.6% had single bilateral CB. NSD was seen in 74.5% of the sample. In the participants with CB, 45.5% showed mild deviation, 34.4% showed moderate deviation, and only 12.5% showed severe septal deviation. CB, but not NSD, was associated with significantly higher MSV on the affected side (P=0.001). Conclusion Although NSD was observed in more than two-thirds of the sample and CB was present in more than one-third of the sample, only CB had a significant impact on MSV.

  • Bone texture fractal dimension analysis of ultrasound-treated bone around implant site: A double-blind clinical trial
    Elaf Akram Abdulhameed, Natheer Hashim Al-Rawi, Asmaa Tahseen Uthman, and Ab Rani Samsudin

    Hindawi Limited
    Objectives. To evaluate the efficacy of bone texture fractal dimension (FD) analysis method in predicting implant stability from intraoral periapical radiographs using two implant protocols. Materials and Methods. A double-blind clinical trial was conducted on 22 subjects who needed dental implants. The participants were randomized into two groups, the control group with standard implant protocol treatment and the intervention group with added low-intensity power ultrasound treatment (LIPUS) besides the standard implant protocol. The FD values of bone density were carried out on the mesial and distal sides of the implant on digital intraoral radiographs using the box-counting method. Both resonance frequency (RF) and fractal dimension (FD) were assessed in three time intervals: after surgery and before and after loading. Results. FD on both the mesial and distal sides serve as very good-to-excellent tests with high validity (ROC area exceeding 0.8) in predicting high implant stability (ISQ ≥ 70). The mesial side measurements were consistently better than the distal side among the intervention groups. The optimum cutoff value for the FD-mesial side that predicts a highly stable implant (ISQ ≥ 70) is ≥1.505. At this optimum cutoff value, the mesial side FD is associated with a perfect sensitivity (100%) and fairly high specificity (86.5%). Conclusion. The FD analysis could be recommended as an adjunctive quantitative method in prediction of the implant stability with very high sensitivity and specificity. This trial is registered with ISRCTN72648040.

  • Shisha Smoking Habit among Dental School Students in the United Arab Emirates: Enabling Factors and Barriers
    Natheer H. Al-Rawi, Ahmed S. Alnuaimi, and Asmaa T. Uthman

    Hindawi Limited
    Objectives. The objective of the present study was to assess shisha smoking among dental school students in Sharjah, United Arab Emirates (UAE). In addition, the role of suggested barriers and enabling factors in shisha smoking was also evaluated.Methods. A cross-sectional questionnaire-based survey was conducted at the College of Dental Medicine, University of Sharjah, between February and May 2016. The questions were adapted from previously published water pipe smoking studies. The collected data were analyzed to identify the relationship between shisha smoking and sociodemographic characteristics. Relevant questions were further categorized as enabling factors and barriers for shisha smoking.Results. Three enabling questionnaire items related to social environment were significantly associated with an increased risk of being a current smoker. The most powerful is peer pressure (“friends smoke shisha”), which increased the odds ratio of shisha smoking 11.3 times, followed by smoker sibling with increase in odd ratio by 4.52 times, then the belief of social acceptance with increase in odd ratio by 4.31 times.Conclusion. Shisha smoking is a serious problem among university students. Any intervention program in the university curricula should consider teaching students that shisha is no less risky than cigarettes and is addictive.

  • Spatial analysis of mandibular condyles in patients with temporomandibular disorders and normal controls using cone beam computed tomography
    Natheer Hashim Al-Rawi, Asmaa Tahseen Uthman, and Sahar M. Sodeify

    Georg Thieme Verlag KG
    ABSTRACT Objectives: The aim of the study is to investigate the condylar position and its relation to articular eminence and axial condylar angle in temporomandibular joint disorder (TMD) patients and in normal controls using cone beam computed tomography (CBCT). Materials and Methods: CBCT temporomandibular joint (TMJ) images of 70 participants (38 males and 32 females, mean age 26.4 years) were analyzed. They were divided into control group (including 35 subjects) and study group (including 35 subjects). Linear measurements of joint space and condyle determined the condylar position of each TMJ. Articular eminence height and inclination were also measured with axial condylar angle to determine its relation to condylar position. Independent and paired sample t-test was applied to compare between the groups and TMJ sides of the same group at significance level of 0.05. Results: Statistical significant differences were found between males and females of both groups regarding superior joint space (SJS), lateral joint space, A-P, and M-L condyle distance (P &lt; 0.05). SJS, medial joint space (MJS), and eminence angle were greater (P &lt; 0.01) in male's joints with TMD with flatter axial condylar angle (P &lt; 0.05), when compared with normal TMJ counterpart. Females TMJs showed significantly higher values of MJS of affected side when compared with normal counterpart with flatter axial condylar angle (P &lt; 0.05). Conclusion: Superior and MJS parameters were the ones that showed significant differences between affected and nonaffected joints. The mean axial condylar angle was smaller in joints with abnormal TMJ. This indicates that the condyles of the affected joints may rotate inward.

  • Carotid artery atheromas and calcifications among postmenopausal women with diabetes and hypertension


  • Evaluation of foramen magnum in gender determination using helical CT scanning
    AT Uthman, NH Al-Rawi, and JF Al-Timimi

    British Institute of Radiology
    OBJECTIVE The present research was undertaken to study the accuracy and reliability of the foramen magnum (FM) and some cranial measurements in gender classification through the use of reconstructed helical CT images. METHODS 88 patients (43 males and 45 females; age range, 20-49 years) were selected for this study. FM sagittal diameter, transverse diameter, area and circumference were measured and data were subjected to discriminant analysis for gender using multiple regression analysis. RESULTS FM circumference and area were the best discriminant parameters that could be used to study sexual dimorphism with an overall accuracy of 67% and 69.3%, respectively. By using multivariate analysis, 90.7% of FM dimensions of males and 73.3% of FM dimensions of females were sexed correctly. CONCLUSION It can be concluded that the reconstructed CT image can provide valuable measurements for the FM and could be used for sexing when other methods are inconclusive.

  • Carotid artery atheromas and calcifications among postmenopausal women with histories of cerebrovascular or cardiovascular problems
    Asmaa T. Uthman, Lamia H. Al-Nakib, Baydaa H. Al-Saleem, and Ahmed S. Al-Naimi

    Springer Science and Business Media LLC

  • Evaluation of maxillary sinus dimensions in gender determination using helical CT scanning
    Asmaa T. Uthman, Natheer H. Al-Rawi, Ahmed S. Al-Naaimi, and Jalal F. Al-Timimi

    Wiley
    Abstract:  Gender determination is an important step in identification in forensic medicine. CT measurements of maxillary sinuses may be useful to support gender identification. This study was undertaken to study the accuracy and reliability of maxillary sinus dimensions measurement in gender classification through the use of reconstructed helical CT images. Eighty‐eight patients (43 men and 45 women) with age range from 20 to 49 years were selected in this study. The width, length, and height of the maxillary sinuses in addition to the total distance across both sinuses were measured. Data were subjected to discriminant analysis for gender using multiple regression analysis. Maxillary sinus height was the best discriminant parameter that could be used to study sexual dimorphism with an overall accuracy of 71.6%. Using multivariate analysis, 74.4% of male sinuses and 73.3% of female sinuses were sexed correctly. The overall percentage for sexing maxillary sinuses correctly was 73.9%. It can be concluded that reconstructed CT image can provide valuable measurements for maxillary sinuses and could be used for sexing when other methods of sexing are not conclusive.

  • Evaluation of frontal sinus and skull measurements using spiral CT scanning: An aid in unknown person identification
    Asmaa T. Uthman, Natheer H. AL-Rawi, Ahmed S. Al-Naaimi, Ahmed S. Tawfeeq, and Enas H. Suhail

    Elsevier BV