MILIND CHITNIS

@wsu.ac.za

Associate Professor, Department of Paediatric Surgery
Frere Hospital, affilciated to Walter Sisulu University



                             

https://researchid.co/asude9256

Dr Milind Chitnis is the Associate Professor and Head of the Department of Paediatric Surgery at the East London Hospital Complex, affiliated with the Walter Sisulu University in East London, South Africa. He has been the Honorary Secretary of the College of Paediatric Surgeons of South Africa for the 2020-2023 period and a member of the Council of the College of Paediatric Surgeons of South Africa for 2017-2026. He is a board member of the Global Initiative for Children’s Surgery (2020-2026) and the Honorary Secretary of the Pan African Association of Paediatric Surgeons (PAPSA) for 2023-2027. He is also a founding Trustee of the NPO- Eyabantwana for the Children- which supports the needs of the Department of Paediatric Surgery in East London. He is passionate about improving Paediatric Surgical care and training in low- and middle-income countries in general and Africa in particular.

EDUCATION

Certificate in Paediatric Surgery 2004 College of Medicine of South Africa

Master of Chirurgiae (MCh) 1989 Bombay (Mumbai) University, India
(Paediatric Surgery)

Master of Surgery (MS)
(General Surgery) 1986 University of Poona (Pune), India

Bachelor of Medicine & Bachelor
of Surgery (MBBS) 1982 University of Poona (Pune), India

RESEARCH, TEACHING, or OTHER INTERESTS

Surgery, Pediatrics

20

Scopus Publications

511

Scholar Citations

10

Scholar h-index

10

Scholar i10-index

Scopus Publications

  • Trauma and sexual abuse in children—Epidemiology, challenges, management strategies and prevention in lower- and middle-income countries
    Abdelbasit E Ali, Shilpa Sharma, Olumide A Elebute, Adesoji Ademuyiwa, Noxolo Z. Mashavave, Milind Chitnis, Simone Abib, and Fazal Nouman Wahid

    Elsevier BV

  • Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions
    SelloS Machaea, MilindR Chitnis, and Phumza Nongena

    Medknow
    Context: Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income countries. In low to middle income countries, such as in Southern Africa, however, there is as much as 84% mortality among patients with gastroschisis. This is thought to be due to factors such as lack of antenatal screening, access to neonatal intensive care services and parenteral nutrition. Aims: The purpose of this study was to calculate the prevalence of gastroschisis and report on its neonatal mortality in the Eastern Cape Province of South Africa. Settings and Design: A retrospective observational study on all neonates with gastroschisis, presenting to a tertiary facility offering paediatric surgical services within the Eastern Cape Province from 1 January 2016 to 31 December 2018. Subjects and Methods: A convenience sampling method was used in retrieving patient files for the study period. Statistical analysis used: Stata version 13. Results: Thirty-seven neonates were included in the study. The prevalence of gastroschisis ranged from 0.07% to 0.18% throughout the 3-year study. The majority (81%) of the neonates were outborn and delivered by mode of caesarean section. Nearly 60% (n = 22) were female. 54% (n = 20) of neonates died within the neonatal period. Conclusions: The majority of the neonates in this study were outborn and female. Although their mortality rate was higher than reported in high-income countries, it was much improved from what is reported in the low to middle income countries.

  • Long proximal pouch oesophageal atresia with tracheo-oesophageal fistula, a diagnostic dilemma: case report
    Sello Machaea, Vuyo Nogela, and Milind Chitnis

    Egypts Presidential Specialized Council for Education and Scientific Research
    Abstract Background Oesophageal atresia is a congenital abnormality commonly encountered in neonates. Classification proposed by Gross is the most frequently used. It divides the oesophageal anomalies into five types. Type C—proximal oesophageal atresia and distal tracheo-oesophageal fistula—is the most common. Dafoe and Ross described a rare subtype with a long proximal pouch. Only 11 cases of a long proximal pouch have been reported in the English literature so far. We describe a neonate with long proximal pouch oesophageal atresia with distal tracheo-oesophageal fistula emphasizing the difficulty in arriving at the diagnosis. Case presentation A 1-week-old neonate presented with feed intolerance and failure to advance orogastric tube into the stomach. Water soluble upper gastrointestinal tract contrast revealed a blind ending proximal oesophagus at the level of the diaphragm. Gastric volvulus was considered as a diagnosis. Patient underwent a laparotomy where a normal stomach was found. Bubbles were seen coming from the fashioned gastrostomy with each inspiration. This prompted us to consider the possibility of a missed oesophageal atresia with distal tracheo-oesophageal fistula. Diagnosis was confirmed on bronchoscopy and right thoracotomy. The tracheo-oesophageal fistula was ligated and a cervical oesophagostomy and Stamm gastrostomy were performed due to irreparable tear in the long upper pouch. Conclusion This rare subtype of long upper pouch oesophageal atresia poses a diagnostic dilemma that can result in delay in the diagnosis and management. This diagnosis should be suspected if the tip of the orogastric/feeding tube is seen to be far below the level of the carina.

  • Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
    BMJ
    IntroductionChildhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality.MethodsProspective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months.ResultsAll-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3–11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality.ConclusionsChildren with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer.

  • Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study
    Prasanna Gomes, Jacqueline Montoya Vasquez, Daniel H Rhee, S. Cooper and Y. Kara

    BMJ
    ObjectivesPaediatric cancer is a leading cause of death for children. Children in low-income and middle-income countries (LMICs) were four times more likely to die than children in high-income countries (HICs). This study aimed to test the hypothesis that the COVID-19 pandemic had affected the delivery of healthcare services worldwide, and exacerbated the disparity in paediatric cancer outcomes between LMICs and HICs.DesignA multicentre, international, collaborative cohort study.Setting91 hospitals and cancer centres in 39 countries providing cancer treatment to paediatric patients between March and December 2020.ParticipantsPatients were included if they were under the age of 18 years, and newly diagnosed with or undergoing active cancer treatment for Acute lymphoblastic leukaemia, non-Hodgkin’s lymphoma, Hodgkin lymphoma, Wilms’ tumour, sarcoma, retinoblastoma, gliomas, medulloblastomas or neuroblastomas, in keeping with the WHO Global Initiative for Childhood Cancer.Main outcome measureAll-cause mortality at 30 days and 90 days.Results1660 patients were recruited. 219 children had changes to their treatment due to the pandemic. Patients in LMICs were primarily affected (n=182/219, 83.1%). Relative to patients with paediatric cancer in HICs, patients with paediatric cancer in LMICs had 12.1 (95% CI 2.93 to 50.3) and 7.9 (95% CI 3.2 to 19.7) times the odds of death at 30 days and 90 days, respectively, after presentation during the COVID-19 pandemic (p<0.001). After adjusting for confounders, patients with paediatric cancer in LMICs had 15.6 (95% CI 3.7 to 65.8) times the odds of death at 30 days (p<0.001).ConclusionsThe COVID-19 pandemic has affected paediatric oncology service provision. It has disproportionately affected patients in LMICs, highlighting and compounding existing disparities in healthcare systems globally that need addressing urgently. However, many patients with paediatric cancer continued to receive their normal standard of care. This speaks to the adaptability and resilience of healthcare systems and healthcare workers globally.

  • Clinical presentation and management of childhood intussusception in South Africa
    Sharon Cox, Aletha Withers, Marion Arnold, Milind Chitnis, Corné de Vos, Mari Kirsten, Susanna M. le Grange, Jerome Loveland, Sello Machaea, Ashwini Maharaj,et al.

    Springer Science and Business Media LLC
    Abstract Purpose We assessed management and outcomes for intussusception at nine academic hospitals in South Africa. Methods Patients ≤ 3 years presenting with intussusception between September 2013 and December 2017 were prospectively enrolled at all sites. Additionally, patients presenting between July 2012 and August 2013 were retrospectively enrolled at one site. Demographics, clinical information, diagnostic modality, reduction methods, surgical intervention and outcomes were reviewed. Results Four hundred seventy-six patients were enrolled, [54% males, median age 6.5 months (IQR 2.6–32.6)]. Vomiting (92%), bloody stool (91%), abdominal mass (57%), fever (32%) and a rectal mass (29%) represented advanced disease: median symptom duration was 3 days (IQR 1–4). Initial reduction attempts included pneumatic reduction (66%) and upfront surgery (32%). The overall non-surgical reduction rate was 28% and enema perforation rate was 4%. Surgery occurred in 334 (70%), 68 (20%) patients had perforated bowel, bowel resection was required in 61%. Complications included recurrence (2%) and nosocomial sepsis (4%). Length of stay (LOS) was significantly longer in patients who developed complications. Six patients died—a mortality rate of 1%. There was a significant difference in reduction rates, upfront surgery, bowel resection, LOS and mortality between centres with shorter symptom duration compared longer symptom duration. Conclusion Delayed presentation was common and associated with low success for enema reduction, higher operative rates, higher rates of bowel resection and increased LOS. Improved primary health-care worker education and streamlining referral pathways might facilitate timely management.

  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
    Naomi Jane Wright, Andrew J.M. Leather, Niyi Ade-Ajayi, Nick Sevdalis, Justine Davies, Dan Poenaru, Emmanuel Ameh, Adesoji Ademuyiwa, Kokila Lakhoo, Emily Rose Smith,et al.

    Elsevier BV
    Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030. Funding Wellcome Trust.

  • Evaluation of intussusception after oral monovalent rotavirus vaccination in South Africa
    Michelle J Groome, Jacqueline E Tate, Marion Arnold, Milind Chitnis, Sharon Cox, Corné de Vos, Mari Kirsten, Susanna M le Grange, Jerome Loveland, Sello Machaea,et al.

    Oxford University Press (OUP)
    Abstract Background Postlicensure studies have shown an association between rotavirus vaccination and intussusception. We assessed the risk of intussusception associated with Rotarix (RV1) administration, at 6 and 14 weeks of age, in an upper-middle-income country, South Africa. Methods Active prospective surveillance for intussusception was conducted in 8 hospitals from September 2013 through December 2017. Retrospective case enrollment was done at 1 hospital from July 2012 through August 2013. Demographic characteristics, symptom onset, and rotavirus vaccine status were ascertained. Using the self-controlled case-series method, we estimated age-adjusted incidence rate ratios within 1–7, 8–21, and 1–21 days of rotavirus vaccination in children aged 28–275 days at onset of symptoms. In addition, age-matched controls were enrolled for a subset of cases (n = 169), and a secondary analysis was performed. Results Three hundred forty-six cases were included in the case-series analysis. Post–dose 1, there were zero intussusception cases within 1–7 days, and 5 cases within 8–21 days of vaccination. Post–dose 2, 15 cases occurred within 1–7 days, and 18 cases within 8–21 days of vaccination. There was no increased risk of intussusception 1–7 days after dose 1 (no cases observed) or dose 2 (relative incidence [RI], 1.71 [95% confidence interval {CI} .83–3.01]). Similarly, there was no increased risk 8–21 days after the first (RI, 4.01 [95% CI, .87–10.56]) or second dose (RI, .96 [95% CI, .52–1.60]). Results were similar for the case-control analysis. Conclusions The risk of intussusception in the 21 days after the first or second dose of RV1 was not higher than the background risk among South Africa infants. Clinical Trials Registration South African National Clinical Trial Register (DOH-27-0913-4183).

  • Global Initiative for Children’s Surgery: A Model of Global Collaboration to Advance the Surgical Care of Children
    , Naomi Wright, Guy Jensen, Etienne St‐Louis, David Grabski, Yasmine Yousef, Neema Kaseje, Laura Goodman, Jamie Anderson, Emmanuel Ameh,et al.

    Wiley
    AbstractBackgroundRecommendations by the Lancet Commission on Global Surgery regarding surgical care in low‐ and middle‐income countries (LMICs) require development to address the needs of children. The Global Initiative for Children’s Surgery (GICS) was founded in 2016 to identify solutions to problems in children’s surgery by utilizing the expertise of practitioners from around the world. This report details this unique process and underlying principles.MethodsThree global meetings convened providers of surgical services for children. Through working group meetings, participants reviewed the status of global children’s surgery to develop priorities and identify necessary resources for implementation. Working groups were formed under LMIC leadership to address specific priorities. By creating networking opportunities, GICS has promoted the development of LMIC‐LMIC and HIC‐LMIC partnerships.ResultsGICS members identified priorities for children’s surgical care within four pillars: infrastructure, service delivery, training and research. Guidelines for provision of care at every healthcare level based on these pillars were created. Seventeen subspecialty, LMIC chaired working groups developed the Optimal Resources for Children’s Surgery (OReCS) document. The guidelines are stratified by subspecialty and level of health care: primary health center, first‐, second‐ and third‐level hospitals, and the national children’s hospital. The OReCS document delineates the personnel, equipment, facilities, procedures, training, research and quality improvement components at all levels of care.ConclusionWorldwide collaboration with leadership by providers from LMICs holds the promise of improving children’s surgical care. GICS will continue to evolve in order to achieve the vision of safe, affordable, timely surgical care for all children.

  • Optimal Resources for Children’s Surgical Care: Executive Summary
    , David Grabski, Emmanuel Ameh, Doruk Ozgediz, Keith Oldham, Francis A. Abantanga, Mohamed Abdelmalak, Nurudeen Abdulraheem, Niyi Ade‐Ajayi, Edna Adan Ismail,et al.

    Wiley

  • Laparoscopically inserted button colostomy as a venting stoma and access port for the administration of antegrade enemas in African degenerative leiomyopathy


  • Retrospective surveillance of intussusception in South Africa, 1998-2003
    S. W. Moore, M. Kirsten, E. W. Müller, A. Numanoglu, M. Chitnis, E. Le Grange, B. Banieghbal, and G. P. Hadley

    Oxford University Press (OUP)
    BACKGROUND Intussusception is a common gastrointestinal emergency in children and appears to have a somewhat different clinical spectrum in developing countries. Its etiology is still unclear, but a link to infective agents and viruses has been highlighted. This study aimed to assess the clinical spectrum and prevalence of intussusception in children from the diverse South African population. METHODS Retrospective data were obtained from 9 participating pediatric referral units on the occurrence of intussusception in South African children (<14 years old) during a 6-year period (1998-2003). Results were correlated with national population statistics. Intussusception was anatomically classified into ileoileal, ileocolic, and colocolic types. The clinical features, management, outcome, and possible causes were examined. RESULTS We reviewed the occurrence and clinical spectrum of intussusception in 423 children (age, 0-14 years) presenting with acute intussusception to 9 pediatric surgical centers. The mean duration of symptoms was 1.5 days, but a delayed presentation was common (median delay, 2.3 days). Intussusception occurred throughout the year, with a peak in the summer months. The majority of patients (89%) were <2 years old, and 78% presented at age 3-18 months of age. Crude population estimates indicate an occurrence of 1 case per 3123 population <2 years old. Only 11% of patients presented after 2 years of age, and the age at presentation was significantly lower (P < .05) in black African patients. All ethnic groups were affected. In 84% of patients, intussusception occurred at the ileocolic region junction, in 7% it was ileoileal, and in 9% it was colocolic. Colocolic intussusception appeared more common in black African patients, and associated pathologic conditions (polyps and Burkitt's lymphoma) occurred mainly in older children. Surgical intervention was required in 81% of patients and involved resection of gangrenous bowel in 40%. CONCLUSION Intussusception appears to be a relatively frequent occurrence in children in South Africa. Although the clinical spectrum appears to vary, there is an apparent link to intestinal infection, which requires further investigation. A collaborative approach is required to ascertain the relationship of intussusception to preventable infections and to improve its diagnosis and management.

  • Atypical antipsychotic (clozapine) self-poisoning in late pregnancy presenting with absent fetal heart rate variability without acidosis and delayed peristalsis in the newborn baby: A case report
    N. NOVIKOVA, M. CHITNIS, V. LINDER, and G. J. HOFMEYR

    Wiley
    A case of an attempted suicide with atypical antipsychotic (clozapine) in late pregnancy is reported. Toxic effects of clozapine in the mother as well as in the fetus and newborn were observed. It should be remembered as a rare cause of unexplained loss of consciousness in pregnant women, a cause of abnormalities on fetal cardiotocogram as well as a cause of delayed peristalsis in a newborn baby.

  • The spectrum of anorectal malformations in Africa
    S. W. Moore, A. Alexander, D. Sidler, J. Alves, G. P. Hadley, A. Numanoglu, B. Banieghbal, M. Chitnis, D. Birabwa-Male, B. Mbuwayesango,et al.

    Springer Science and Business Media LLC

  • Hepatocellular carcinoma and liver tumors in South African children: A case for increased prevalence
    Samuel W. Moore, Alistair J. W. Millar, G. P. (Larry) Hadley, Gabriel Ionescu, Mariana Kruger, Janet Poole, David Stones, Linda Wainwright, Milind Chitnis, and Glynn Wessels

    Wiley
    AbstractBACKGROUNDThe high regional incidence of hepatocellular carcinoma (HCC) in South Africa also may be present in children of the region, although the link to hepatitis B (HBV) appears less clear. The objective of this study was to assess the incidence and probable causes of HCC in South African children.METHODSData were obtained from seven participating pediatric oncology units and from the tumor registry to review hepatic tumors in children in South Africa.RESULTSOne hundred ninety‐four children (ages 0–14 years) presented with malignant primary hepatic tumors (1988–2003). One hundred twelve tumors (57%) were hepatoblastoma (HB), 68 tumors (35%) were hepatocellular carcinoma (HCC) (including 9 patients with the fibrolamellar variant, 6 of which occurred in black children), 10 tumors (5%) were sarcoma of the liver, and 4 tumors were lymphoma. The ratio of HB to HCC (1.67) was markedly lower compared with other reports, suggesting a greater prevalence of HCC. Correlation with population statistics indicated an incidence of 1.066 malignant liver tumors per year per 106 children age &lt; 14 years (HB, 0.61 per 106 children; HCC, 0.39 per 106). Two‐thirds of patients with HCC were positive for HBV surface antigen (HBsAg), and HCC occurred mostly in black African patients (93%). The mean age of onset was 1.47 years for HB and 10.48 years for HCC. A preponderance of males (3.5:1.0) was noted in the HBsAg‐positive group that was not reflected elsewhere. Serum α‐fetoprotein (AFP) levels were raised both in patients with HB (100%; most AFP levels were very high) and in patients with HCC (69%), although 15% of patients with HCC had low or normal AFP levels.CONCLUSIONSIt appeared from the current results that HCC is more prevalent among children in South Africa compared with the children in more developed countries, although their rates were lower that the rates noted in adults. A collaborative approach will be required to improve their diagnosis and management. Cancer 2004. © 2004 American Cancer Society.

  • Preoperative angioembolisation for life-threatening haemorrhage from Wilms' tumour: A case report
    M. Chitnis, S.K. Chowdhary, and C. Lazarus

    Springer Science and Business Media LLC


  • Application of the Malone antegrade continence enema principle in degenerative leiomyopathy
    M. Chitnis, S. Chowdhary, and C. Lazarus

    Springer Science and Business Media LLC

  • Pediatric Parenteral Nutrition: South African Model and its Relevance to the Developing Countries


  • Hypothyroldism in a neonate following excision of a cervical teratoma
    S. K. Chowdhary, M. Chitnis, J. Perold, and C. Lazarus

    Springer Science and Business Media LLC

RECENT SCHOLAR PUBLICATIONS

  • GAPS II: Development and Pilot Results of the Global Assessment in Pediatric Surgery, an Evidence-Based Pediatric Surgical Capacity Assessment Tool for Low-Resource Settings
    Y Yousef, S Cairo, E St-Louis, LF Goodman, DM Hamad, R Baird, ...
    2024

  • Trauma and Sexual abuse in children–Epidemiology, Challenges, Management strategies and Prevention in lower-and middle-income countries
    AE Ali, S Sharma, OA Elebute, A Ademuyiwa, NZ Mashavave, M Chitnis, ...
    Seminars in Pediatric Surgery, 151356 2023

  • Microorganisms detected in intussusception cases and controls in children< 3 years in South Africa from 2013 to 2017
    NA Page, R Netshikweta, JE Tate, SA Madhi, UD Parashar, MJ Groome, ...
    Open Forum Infectious Diseases 10 (9), ofad458 2023

  • Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions
    SS Machaea, MR Chitnis, P Nongena
    African Journal of Paediatric Surgery 20 (1), 46-50 2023

  • Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study
    Global Health Research Group on Children’s Non-Communicable Diseases ...
    BMJ open 12 (4), e054690 2022

  • Long proximal pouch oesophageal atresia with tracheo-oesophageal fistula, a diagnostic dilemma: case report
    S Machaea, V Nogela, M Chitnis
    Annals of Pediatric Surgery 18 (1) 2022

  • Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
    EM Der
    BMJ Publishing Group Ltd. 2022

  • Clinical presentation and management of childhood intussusception in South Africa
    S Cox, A Withers, M Arnold, M Chitnis, C De Vos, M Kirsten, ...
    Pediatric Surgery International 37 (10), 1361-1370 2021

  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective
    NJ Wright, AJM Leather, N Ade-Ajayi, N Sevdalis, J Davies, D Poenaru, ...
    The Lancet 398 (10297), 325-339 2021

  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-, middle-and high-income countries: a multicentre, international, prospective cohort study
    N Hall, N Wright
    The Lancet 2021

  • Evaluation of intussusception after oral monovalent rotavirus vaccination in South Africa
    MJ Groome, JE Tate, M Arnold, M Chitnis, S Cox, C De Vos, M Kirsten, ...
    Clinical Infectious Diseases 70 (8), 1606-1612 2020

  • Global initiative for children’s surgery: a model of global collaboration to advance the surgical care of children
    Global Initiative for Children’s Surgery, N Wright, G Jensen, E St‐Louis, ...
    World Journal of Surgery 43 (6), 1416-1425 2019

  • Optimal resources for children’s surgical care: executive summary
    Global Initiative for Children’s Surgery, D Grabski, E Ameh, D Ozgediz, ...
    World Journal of Surgery 43 (4), 978-980 2019

  • The global initiative for children's surgery: optimal resources for improving care
    LF Goodman, E St-Louis, Y Yousef, M Cheung, B Ure, D Ozgediz, ...
    European Journal of Pediatric Surgery 28 (01), 051-059 2018

  • Bronchoscopic removal of aspirated foreign bodies: an essential skill for a paediatric surgeon working in the developing world
    M Chitnis, D von Delft, R Spence, C Lazarus
    Bangladesh Journal of Endosurgery 1 (1), 4-8 2013

  • Laparoscopically inserted button colostomy as a venting stoma and access port for the administration of antegrade enemas in African degenerative leiomyopathy
    M Chitnis, C Lazarus, I Simango, M Elsen, C Van Rensburg, D Von Delft, ...
    South African Journal of Surgery 49 (1), 44-46 2011

  • Retrospective surveillance of intussusception in South Africa, 1998–2003
    SW Moore, M Kirsten, EW Muller, A Numanoglu, M Chitnis, E Le Grange, ...
    Journal of infectious diseases 202 (Supplement_1), S156-S161 2010

  • The spectrum of anorectal malformations in Africa
    SW Moore, A Alexander, D Sidler, J Alves, GP Hadley, A Numanoglu, ...
    Pediatric surgery international 24, 677-683 2008

  • Anorectal malformation In Africa (abstract 119). South African Paediatric Review
    SW Moore, A Alexander, GP Hadley, A Nomonoglu, B Banieghbal, ...
    2006

  • Hepatocellular carcinoma and liver tumors in South African children: a case for increased prevalence
    SW Moore, AJW Millar, GP Hadley, G Ionescu, M Kruger, J Poole, ...
    Cancer: Interdisciplinary International Journal of the American Cancer 2004

MOST CITED SCHOLAR PUBLICATIONS

  • The global initiative for children's surgery: optimal resources for improving care
    LF Goodman, E St-Louis, Y Yousef, M Cheung, B Ure, D Ozgediz, ...
    European Journal of Pediatric Surgery 28 (01), 051-059 2018
    Citations: 93

  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective
    NJ Wright, AJM Leather, N Ade-Ajayi, N Sevdalis, J Davies, D Poenaru, ...
    The Lancet 398 (10297), 325-339 2021
    Citations: 73

  • Hepatocellular carcinoma and liver tumors in South African children: a case for increased prevalence
    SW Moore, AJW Millar, GP Hadley, G Ionescu, M Kruger, J Poole, ...
    Cancer: Interdisciplinary International Journal of the American Cancer 2004
    Citations: 65

  • The spectrum of anorectal malformations in Africa
    SW Moore, A Alexander, D Sidler, J Alves, GP Hadley, A Numanoglu, ...
    Pediatric surgery international 24, 677-683 2008
    Citations: 63

  • Global initiative for children’s surgery: a model of global collaboration to advance the surgical care of children
    Global Initiative for Children’s Surgery, N Wright, G Jensen, E St‐Louis, ...
    World Journal of Surgery 43 (6), 1416-1425 2019
    Citations: 46

  • Optimal resources for children’s surgical care: executive summary
    Global Initiative for Children’s Surgery, D Grabski, E Ameh, D Ozgediz, ...
    World Journal of Surgery 43 (4), 978-980 2019
    Citations: 42

  • Retrospective surveillance of intussusception in South Africa, 1998–2003
    SW Moore, M Kirsten, EW Muller, A Numanoglu, M Chitnis, E Le Grange, ...
    Journal of infectious diseases 202 (Supplement_1), S156-S161 2010
    Citations: 41

  • Evaluation of intussusception after oral monovalent rotavirus vaccination in South Africa
    MJ Groome, JE Tate, M Arnold, M Chitnis, S Cox, C De Vos, M Kirsten, ...
    Clinical Infectious Diseases 70 (8), 1606-1612 2020
    Citations: 34

  • Preoperative angioembolisation for life-threatening haemorrhage from Wilms’ tumour: a case report
    M Chitnis, SK Chowdhary, C Lazarus
    Pediatric surgery international 20 (4), 290-291 2004
    Citations: 14

  • Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study
    Global Health Research Group on Children’s Non-Communicable Diseases ...
    BMJ open 12 (4), e054690 2022
    Citations: 11

  • Clinical presentation and management of childhood intussusception in South Africa
    S Cox, A Withers, M Arnold, M Chitnis, C De Vos, M Kirsten, ...
    Pediatric Surgery International 37 (10), 1361-1370 2021
    Citations: 8

  • Hypothyroldism in a neonate following excision of a cervical teratoma
    SK Chowdhary, M Chitnis, J Perold, C Lazarus
    Pediatric surgery international 14, 212-213 1998
    Citations: 8

  • Laparoscopically inserted button colostomy as a venting stoma and access port for the administration of antegrade enemas in African degenerative leiomyopathy
    M Chitnis, C Lazarus, I Simango, M Elsen, C Van Rensburg, D Von Delft, ...
    South African Journal of Surgery 49 (1), 44-46 2011
    Citations: 5

  • Application of the Malone antegrade continence enema principle in degenerative leiomyopathy
    M Chitnis, S Chowdhary, C Lazarus
    Pediatric surgery international 17, 470-471 2001
    Citations: 4

  • Pediatric parenteral nutrition: South African model and its relevance to the developing countries
    SK Chowdhary, M Chitnis, S Chowdhary, F Gossen, C Lazarus
    Indian Pediatrics 37 (2), 187-192 2000
    Citations: 2

  • Bronchoscopic removal of aspirated foreign bodies: an essential skill for a paediatric surgeon working in the developing world
    M Chitnis, D von Delft, R Spence, C Lazarus
    Bangladesh Journal of Endosurgery 1 (1), 4-8 2013
    Citations: 1

  • Differentiation of a benign myxolipoma from a myxoid liposarcoma by tumour karyotyping-a diagnosis missed
    M Chitnis, T Steyn, P Koeppen, V Breckon, C Lazarus
    Pediatric Surgery International 18 (1), 83-83 2002
    Citations: 1

Publications

Abdelbasit E Ali, Shilpa Sharma, Olumide A Elebute, Adesoji Ademuyiwa, Noxolo Z. Mashavave, Milind Chitnis, Simone Abib, Fazal Nouman Wahid Trauma and sexual abuse in children—Epidemiology, challenges, management strategies and prevention in lower and middle-income countries Seminars in Pediatric Surgery Volume 32, Issue 6, December 2023,
151356

• Machaea SS, Chitnis MR, Nongena P. Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions. Afr J Paediatr Surg 2023; 20:46-50 DOI: 10.4103/


• Evaluation of Intussusception After Oral Monovalent Rotavirus Vaccination in South Africa
Michelle J Groome, Jacqueline E Tate, Marion Arnold, Milind Chitnis, Sharon Cox, Corné de Vos, Mari Kirsten, Susanna M le Grange, Jerome Loveland, Sello Machaea,
Ashwini Maharaj, Nick Andrews, Shabir A Madhi, Umesh D Parashar
Clinical Infectious Diseases, ciz431,
• Collaborating author: Global Initiative for Children’s Surgery: A Model of Global Collaboration to Advance the Surgical Care of Children World Journal of Surgery
June 2019, Volume 43, Issue 6, pp 1416–1425
doi: 10.1007/s00268-018-04887-8.

• Chitnis M, Lazarus C, Simango I, Elsen M, von Delft D, van Rensburg C, Tovell Trollope L. Laparoscopically inserted button col

Industry, Institute, or Organisation Collaboration

Pan African Paediatric Surgical Association
Global Initiative for Children's Surgery
South African Association of Paediatric Surgeons
Eyabantwan for the Children Trust

INDUSTRY EXPERIENCE

Paediatric Surgery- clinical and training