Dr T AUGUSTINE ARUL PRASAD
@dgvaishnavcollege.edu.in
Assistant Professor of Chemistry
D.G.VAISHNAV COLLEGE
EDUCATION
Presidency College, University of Madras
Doctor of Philosophy (Synthetic Organic Chemistry) APRIL -2008
Loyola college, University of Madras
Master of Science in Chemistry, June 2000 with 70%
Loyola college, University of Madras
Bachelor of Science in Chemistry, June 1998 with 72%
St Joseph's A.I.B.H.S.S, Vepery, Chennai
Higher secondary course, May 1995 with 84%
St Joseph's A.I.B.H.S.S, Vepery, Chennai
Anglo Indian School leaving certificate, May 1993 with 88%.
RESEARCH INTERESTS
Green Synthesis nanomaterials, Organic Synthesis
FUTURE PROJECTS
Green Synthesis of bimetallic nano composites
Applications Invited
Scopus Publications
Scopus Publications
T. Jayamani, Augustine Arul Prasad T, J. Edal Queen, B. Scholastica Mary Vithiya, P. Tamizhdurai, Nadavala Siva Kumar, Ahmed S. Al-Fatesh, and Janardhan Reddy Koduru
Elsevier BV
P. Tamizhdurai, V.L. Mangesh, Aboud Ahmed Awadh Bahajjaj, Umamaheswari Rajai, Mani Govindasamy, R. Vasanthi, R. Kumaran, and T. Augustine
Elsevier BV
Athisa Roselyn Maheo, Scholastica Mary Vithiya B, Augustine Arul Prasad T, V. L. Mangesh, Tamizhdurai Perumal, Wahidah H. Al-Qahtani, and Mani Govindasamy
American Chemical Society (ACS)
In the present study, we have improvised a biogenic method to fabricate zinc oxide nanoparticles (ZnO NPs) using chitosan and an aqueous extract of the leaves of Elsholtzia blanda. Characterization of the fabricated products was carried out with the help of ultraviolet–visible, Fourier transform infrared, X-ray diffraction, field emission scanning electron microscopy, high-resolution transmission electron microscopy, selected area electron diffraction, and energy-dispersive X-ray analyses. The size of the improvised ZnO NP measured between 20 and 70 nm and had a spherical and hexagonal shape. The ZnO NPs proved to be highly effective in the antidiabetic test as the sample showed the highest percentage of enzyme inhibition at 74% ± 3.7, while in the antioxidant test, 78% was the maximum percentage of 2,2-diphenyl-1-picrylhydrazyl hydrate scavenging activity. The cytotoxic effect was investigated against the human osteosarcoma (MG-63) cell line, and the IC50 value was 62.61 μg/mL. Photocatalytic efficiency was studied by the degradation of Congo red where 91% of dye degradation was observed. From the various analyses, it can be concluded that the as-synthesized NPs may be suitable for various biomedical applications as well as for environmental remediation.
P. Tamizhdurai, R. Mythily, C. Kavitha, V.L. Mangesh, R. Kumaran, P. Santhana Krishnan, T. Sivaramakrishnan, T. Augustine, Mani Govindasamy, Asma A. Alothman,et al.
Elsevier BV
V.L. Mangesh, P. Tamizhdurai, S. Umasankar, R. Palaniswamy, S. Narayanan, T. Augustine, R. Kumaran, Zeid A. ALOthman, Mohamed Ouladsmane, and Mani Govindasamy
Elsevier BV
Jasmine Jacob, T. Augustine Arul Prasad, B. Scholastica Mary Vithiya, Bindhu Thomas, and R. Vasanthi
Asian Journal of Chemistry
Drug resistant strains are formed due to unsuitable uses of antibiotics and insufficient check of infections. In present years, due to the extensive antimicrobial properties, metallic nanoparticles and metallo-pharmaceutics are highly proposed. Therefore, the synthesis of bimetallic nanoparticles are exploring towards the evolution of more productive amalgamative antimicrobials composed of combined metals. In this study, the green synthesis of Cu-Ag bimetallic nano-alloys using aqueous extract from the leaves of Curcuma aromatica is carried out. Synthesized Cu-Ag nano-alloys were characterized by UV-visible spectroscopy, scanning electron microscope (FE-SEM), transmission electron microscope (TEM-EDAX), cyclic voltammogram (CV). The characterization studies reveals that the biosynthesis produced core-shell Cu-Ag nano-alloys with spherical shape and average diameter size of 15 nm. The synthesized Cu-Ag nanoalloys exhibited antibacterial activity against both Gram-positive and Gram-negative bacteria. The antidiabetic potential of Cu-Ag nanoalloys shows an effective inhibition against α-glucosidase. Anticancerous activity of Cu-Ag nanoalloys indicates its greater efficacy in destroying cancer cells. The biosynthesis of Cu-Ag nanoalloys can be employed in medical and industrial fields on a large scale with cost reductive method.
Athisa Roselyn Maheo, B. Scholastica Mary Vithiya, T. Augustine Arul Prasad, P. Tamizhdurai, and V.L. Mangesh
Elsevier BV
Athisa Roselyn Maheo, B. Scholastica Mary Vithiya, and T. Augustine Arul Prasad
Elsevier BV
Rajendran Kumaran, Somasundaram Gayathri, Thomas Augustine Arul Prasad, Namasivayam Dhenadhayalan, Ravichandran Keerthiga, Suresh Sureka, Kumar Jeevitha, and Pargunan Karthick
Elsevier BV
Photophysical investigation on the fluorescence decay characteristics of L-tryptophan and a derivative N-acetyl-L-tryptophanamide (NATA) with alkyl amides were carried out in water. L-tryptophan exists in the zwitterionic form and exhibits a biexponential lifetime which is correlated to the existence of rotamer structures. Addition of formamide (F) and dimethylformamide (DMF) results in a decrease in the fluorescence lifetime and its proportion of the most stable structure of L-tryptophan wherein acetamide (ACM) results in an increase of the same. Interestingly, all the amides result in the formation of the lifetime of the rotamer whose lifetime doesn't exist initially and the lifetime and its distribution increases irrespective of the nature of amide. The interaction between L-tryptophan and amide is attributed to hydrogen-bonding such that these interactions influence the relative proportion of the existence of individual rotamers in the presence of amides.Strikingly, in the case of NATA that does not exhibit rotamer structures; the fluorescence lifetime is quenched in the presence of F, whereas ACM and DMF result in a larger fold of enhancement resulting in two different lifetimes. The variation in the fluorescence lifetime and amplitude of the various conformers of L-tryptophan and of NATA is completely governed by the concentration of the amides in solution such that the microenvironment surrounding the fluorophores are completely reorganised. The hydrogen-bonding functional groups in amides that are responsible for the coexistence of rotamers are elucidated and well supported by quantum mechanical (QM) studies. Time-correlated single-photon counting(TCSPC) technique is used as a probe as well as marker in establishing the variation in the lifetime properties of L-tryptophan and NATA with non-fluorescent hydrogen-bonding solutes in water which promotes this as fascinating field of research in the context of fluorescence properties of a complicated amino acid-like tryptophan.
Bindu Thomas, B. Scholastica Mary Vithiya, and T. Augustine Arul Prasad
Elsevier BV
Abstract The purpose of this study is to minimize the negative impacts of synthetic procedures and to develop environmentally benign procedures for the synthesis of metallic nanoparticles. In the present study, Passiflora edulis .f. flavicarpa (P.edulis) aqueous leaf extract mediated green synthesis of silver nanoparticles are described. The synthesized silver nanoparticles were characterized by UV-Vis Spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), X-Ray diffraction (XRD), Scanning Electron Microscopy (SEM),) Transmission Electron Microscopy (TEM) .The efficacy of the synthesized silver nanoparticles (AgNPs) was demonstrated as catalyst in the photo catalytic degradation of Methyl Orange and Methylene Blue dyes which were measured spectrophotometrically. The study revealed that biosynthesized silver nanoparticles using Passiflora. Edulis f. flavicarpa, plant extract was found to be very effective as antioxidant agent.
B. Thomas, Augustine Arul Prasad and Scholastica Mary Vithiya
Biosynthesis of metal nanoparticles using plant extract has received much attention due to its eco-friendly nature. The present study elucidates the green synthesize of Silver nanoparticles (AgNPs) from methanolic extract of Coleus Vettiveroids –an endemic species. The synthesis of AgNPs was confirmed by UV-visible spectrometry at 416 nm. Further, biosynthesized nanoparticles were characterized by FTIR for the confirmation of biomolecules acting as reducing agent. Average size and presence of elemental silver were characterized by scanning electron microscopy (SEM) and Transmission electron microscopy (TEM).Average size of nanoparticles was found to be 5 nm. The antioxidant ability of AgNPs was analyzed using DPPH. In vitro antibacterial effect of various concentrations of AgNPs was investigated against both Gram positive (S.Aureus) and Gram negative (E.Coli) bacterial strains. The result shows that biosynthesized AgNPs have significant antibacterial activity. Synthesized silver nanoparticles were also used effectively as photo catalyst in degradation of Organic Dyes and can be concluded that synthesized silver nanoparticles are also promising photo catalyst.
T. Augustine, Scholastica Mary Vithiya, S. Ignacimuthu, and V. Ramkumar
International Union of Crystallography (IUCr)
In the title compound, C29H23NO2, the pyrrolidine ring adopts a twisted conformation about one of the C—N bonds. The acenaphthone ring (r.m.s. deviation = 0.025 Å) lies almost perpendicular to the pyrrolidine ring [dihedral angle = 88.08 (8)°]. The dihedral angle between the phenyl rings is 88.12 (11)°. In the crystal structure, weak C—H⋯π interactions connect the molecules.
T. Augustine, Charles C. Kanakam, Scholastica Mary Vithiya, and V. Ramkumar
Elsevier BV
The cycloaddition reaction of azomethine ylides, generated through decarboxylation, with (E)-3-arylidene-4-chromanones as dipolarophiles has been investigated. A high degree of regioselectivity has been observed in the synthesis of a new class of functionalized dispiroheterocyclic compounds bearing chromanone and acenaphthenequinone framework. The structures were established by spectroscopic techniques as well as single crystal X-ray analysis.
T. Augustine, Scholastica Mary Vithiya, V. Ramkumar, and Charles C. Kanakam
International Union of Crystallography (IUCr)
In the title compound, C17H14O3, the dihedral angle between the phenyl ring and the benzene ring of the chromanone moiety is 67.78 (3)°. The six-membered heterocyclic ring of the chromanone moiety adopts a half-chair conformation. The structure is stabilized by weak intermolecular C—H⋯O interactions that link the molecules into inversion dimers.
T. Augustine, V. Ramkumar, and Charles C. Kanakam
International Union of Crystallography (IUCr)
In the crystal structure of the title compound, C34H25NO3, the dihydropyrone ring is in a half-chair conformation and the five-membered heterocyclic ring is in an envelope conformation.
T. Augustine, V. Ramkumar, S. Arul Antony, and Charles. C. Kanakam
International Union of Crystallography (IUCr)
In the crystal structure of the title compound, C31H25NO4, the five-membered heterocyclic ring is in an envelope conformation and the dihydropyrone ring is in a half-chair conformation.
T. Augustine, Charles C. Kanakam, R. Suresh, Y. Christurajan, and V. Ramkumar
International Union of Crystallography (IUCr)
The title compound, C27H24N2O4, has been synthesized as a potential pharmacologically active compound. All bond lengths and angles are within normal ranges and the molecules are linked into centrosymmetric R22(14) dimers by a simple N—H⋯O interaction. The packing is stabilized through intermolecular N—H⋯O hydrogen bonds and van der Waals interactions.