My research work focus on physical activity and physical exercise as tools to improve quality of life mainly in patients with rheumatic diseases. In addition, my areas of interest expand to the study of the effect of sedentary time and physical activity patterns, sleep, fitness, and body composition
Association of Moderate-to-Vigorous Physical Activity, Sedentary Time, Fat Percentage, and Physical Fitness with Gait Parameters in Women with Fibromyalgia: The Al-Ándalus Project Sergio Llorente-Romero, Manuel Herrador-Colmenero, Pedro Acosta-Manzano, Milkana Borges-Cosic, Blanca Gavilán-Carrera, et al. Biomedicines, 2024 Gait impairments have been found in women with fibromyalgia, reducing the physical activity possibilities in this population and leading to a negative correlation with fibromyalgia impact. The aim of this study was to analyze the individual and independent associations of moderate-to-vigorous physical activity (MVPA), sedentary time, fat percentage, and physical fitness with gait parameters in women with fibromyalgia. A total of 84 women with fibromyalgia were included. MVPA and sedentary time were assessed with accelerometry, fat percentage with bioimpedance analysis, and physical fitness with field-based fitness tests. Gait was assessed during a “6 min walk test” and categorized in velocity, cadence, step length, step cycle duration, unipedal stance phase, and bipedal stance phase. Individual relationships were analyzed by partial correlations and independent relationships by linear regressions, adjusting by age and height. MVPA, sedentary time, fat percentage, and physical fitness were correlated with most gait parameters (rpartial between |0.842| and |0.219|; p ≤ 0.05). Physical fitness was independently associated with all gait parameters (β between |0.346| and |0.761|; p ≤ 0.002). In addition, MVPA was independently associated with velocity and step length (β = 0.241 and 0.292; both p = 0.004), and fat percentage was associated with bipedal stance phase (β = 0.242; p = 0.049). Good levels of MVPA, physical fitness, and adequate weight balance are associated with improved gait parameters in women with fibromyalgia.
No Changes in Body Composition and Adherence to the Mediterranean Diet after a 12-Week Aerobic Training Intervention in Women with Systemic Lupus Erythematosus: The EJERCITA-LES Study Blanca Gavilán-Carrera, Alba Ruiz-Cobo, Francisco José Amaro-Gahete, Alberto Soriano-Maldonado, José Antonio Vargas-Hitos Nutrients, 2023 Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease linked to high cardiovascular risk. To reach an adequate body composition status while maintaining proper dietary habits are effective strategies for reducing cardiovascular risk, both being potentially modified through exercise. This study aimed to evaluate the effects of a 12-week aerobic training intervention on anthropometry, body composition and adherence to the Mediterranean diet in women with SLE. A total of 58 women with SLE were assigned to either an exercise group (EG; n = 26) or a comparison group (CG; n = 32) in this non-randomized controlled trial. The EG comprised 12 weeks of aerobic exercise (two sessions/week) between 40–75% of the individual’s heart rate reserve (calculated as maximum heart rate − resting heart rate) and the CG received usual care. At baseline and after the intervention, the anthropometry (i.e., weight, waist circumference, waist-to-hip ratio, and body mass index) and body composition (i.e., fat mass and lean mass) were assessed using a stadiometer, an anthropometric tape, and a bioimpedance device, respectively. Dietary habits were assessed with the Mediterranean Diet score. There were no between-group differences in neither anthropometric nor body composition parameters (all p > 0.05). Similarly, no between-group differences were obtained in the adherence to the Mediterranean diet after the exercise intervention (all p > 0.05). Contrary to the initial hypothesis, these results suggest that the 12-week aerobic training intervention performed in this study did not improve anthropometry, body composition or adherence to the Mediterranean diet in women with SLE.
Longitudinal association of sedentary time and physical activity with pain and quality of life in fibromyalgia Blanca Gavilán‐Carrera, Manuel Delgado‐Fernández, Inmaculada C. Álvarez‐Gallardo, Pedro Acosta‐Manzano, Milkana Borges‐Cosic, et al. Scandinavian Journal of Medicine and Science in Sports, 2023 OBJECTIVE To analyze changes over time and the predictive value of baseline and changes of sedentary time (ST) and physical activity (PA) on pain, disease impact, and health-related quality of life (HRQoL) at 2- and 5-year follow-up in women with fibromyalgia. METHODS This is a longitudinal and exploratory study with three time points. A total of 427 women with fibromyalgia (51.4 ± 7.6 years) were followed after 2 (n=172) and 5 years (n=185). ST and PA (light and moderate-to-vigorous [MVPA]) were assessed using triaxial accelerometers. Pain, disease impact, and HRQoL were measured using: pressure pain threshold, the pain subscale of the revised fibromyalgia impact questionnaire (FIQR), the bodily pain subscale of the 36-item Short-form health survey (SF-36), a Visual Analog Scale (VAS), the FIQR, and the SF-36 physical and mental components. RESULTS Over 5 years, pressure pain threshold, ST, light PA, and MVPA variables were worsened, while FIQR and SF-36 variables were improved (Cohen's d<0.1 to 0.3). Baseline ST or light PA were not associated with future outcomes, whereas greater MVPA at baseline was associated with better SF-36 bodily pain at 5-year follow-up (β= 0.13). Reducing ST and increasing light PA were associated with better bodily pain (β =-0.16 and 0.17, respectively) and SF-36 physical component (β=-0.20 and 0.17, respectively) at 5-year follow-up. Increasing MVPA was associated with less pain (pressure pain threshold, VAS, FIQR-pain) and better SF-36 physical component at 2- and 5-year follow-up (β's from -0.20 to 0.21). CONCLUSIONS Objectively measured variables slightly worsened over years, while for self-reported outcomes there was a trend for improvement. Reductions in ST and increases in light PA and MVPA were associated with better HRQoL at 5-year follow-up, and increases in MVPA were additionally associated with better pain and HRQoL at 2-year follow-up.
Sedentary time is associated with depressive symptoms and state anxiety in women with fibromyalgia. Could physical activity and fitness modify this association? The al-Ándalus project Blanca Gavilán-Carrera, Manuel Delgado-Fernández, Eugenio Sierra-Nieto, Pedro Acosta-Manzano, Milkana Borges-Cosic, et al. Disability and Rehabilitation, 2023 PURPOSE To analyze the associations of total and prolonged sedentary time (ST) with depressive symptoms and state anxiety in women with fibromyalgia and whether these associations are modified by moderate-to-vigorous physical activity (MVPA) and physical fitness. METHODS This cross-sectional exploratory study included 386 women with fibromyalgia aged 51.2 ± 7.6 years. Total ST, time in prolonged bouts of ST (≥30- and ≥60-min) and MVPA were measured with triaxial accelerometry. Depressive symptoms were assessed with the "Beck Depression Inventory-second edition," state anxiety with the "State-Trait Anxiety Inventory," and physical fitness with the "Senior Fitness Test Battery." RESULTS Total and prolonged ST were directly associated with depressive symptoms (total: β = 0.19, ≥30-min bout: β = 0.15, and ≥60-min bout: β = 0.12) and odds of severe depressive symptoms (all, p < 0.001). These associations generally remained significant after adjustments for MVPA and physical fitness (all, p < 0.05). Total and prolonged ST were directly associated with state anxiety (total: β = 0.11, ≥30-min bout: β = 0.12, and ≥60-min bout: β = 0.07; all, p < 0.001). These associations were generally independent of MVPA (p < 0.05) but vanished when considering physical fitness (p > 0.05). CONCLUSIONS Higher levels of total and prolonged ST are associated with greater depressive symptoms and state anxiety in women with fibromyalgia. MVPA did not modify these associations, although physical fitness could play a protective role specially for state anxiety.IMPLICATIONS FOR REHABILITATIONReducing sedentary time and avoiding its accumulation in prolonged periods could potentially reduce depressive symptoms and state anxiety in fibromyalgia.Higher sedentary time is associated with more severe depressive symptoms even in patients who engage in moderate-to-vigorous physical activity.Higher levels of physical fitness could attenuate the negative associations of sedentary time with depressive symptoms and, specially, state anxiety."Sit less, move more and exercise to increase your fitness" could be a positive message for people with fibromyalgia in clinical settings.
Effectiveness of a 6-month Land-Based and Water-Based Exercise Intervention on Body Composition and Physical Fitness in Women with Fibromyalgia: The al-Ándalus Quasi … LE Bañuelos-Terés, IC Álvarez-Gallardo, B Gavilán-Carrera, ... Archives of Physical Medicine and Rehabilitation , 2026 2026
If exercise is medicine, where is the dose? A call to improve reporting and monitoring of exercise interventions in fibromyalgia research B Gavilán-Carrera, ÁJ Rodríguez-Domínguez, JC Tortosa-González, ... Frontiers in Sports and Active Living 8, 1777261 , 2026 2026
Light, but not moderate or vigorous, physical activity is consistently associated with higher levels of positive psychology resources and outcomes in women with fibromyalgia: a … MJ Arrayás-Grajera, F Estévez-López, B Gavilán-Carrera, O Luque-Reca, ... Rheumatology International 46 (1), 26 , 2026 2026
Unraveling the Potential of Physical Activity and High-Intensity Interval Training in the Treatment of Familial Hypercholesterolemia: Impact on Cardiorespiratory Fitness … JA Vargas Hitos, P González-Bustos, MJ Martín-Jáimez, A Díaz Chamorro, ... medRxiv, 2025.12. 22.25342692 , 2025 2025
Rúbrica de autoevaluación y coevaluación para ejercicio de conjunto Fundamentos de los Deportes II: Gimnasia Rítmica B Gavilán-Carrera 2025
Association of the Mediterranean diet with arterial stiffness, inflammation, and medication use in women with systemic lupus erythematosus: An exploratory study B Gavilán-Carrera, V Aguilera-Fernández, FJ Amaro-Gahete, ... The Journal of Nutritional Biochemistry 134, 109759 , 2024 2024 Citations: 7
Associations of physical activity, sedentary time, and fitness with cardiovascular risk and atherosclerosis over 3 years in women with systemic lupus erythematosus B Gavilán-Carrera, E Martínez-Rosales, C Palacios-Morenilla, ... Medicina clínica 163 (7), 327-335 , 2024 2024 Citations: 4
OP0209-HPR NETWORKS OF FATIGUE, PAIN, AND BIOPSYCHOSOCIAL FACTORS IN PEOPLE WITH RHEUMATOID ARTHRITIS. THE NET-RMDS STUDY R Geenen, B Gavilán-Carrera, F Estevez-Lopez, L Boschloo, M Visser, ... Annals of the Rheumatic Diseases 83, 195-196 , 2024 2024
Networks of fatigue, pain, and biopsychosocial factors in people with rheumatoid arthritis. The NET-RMDs study B Gavilan-Carrera, L Boschloo, M Visser, C Hughes, R Ferreira, ... European Congress of Rheumatology , 2024 2024
Networks of fatigue, pain, and biopsychosocial factors in people with Sjögren’s disease M Visser, B Gavilan-Carrera, R Greenan, C Hughes, L Barbosa, ... 16th International Symposium Sjorgen's Disease: Looking Forward , 2024 2024
Association of Moderate-to-Vigorous Physical Activity, Sedentary Time, Fat Percentage, and Physical Fitness with Gait Parameters in Women with Fibromyalgia: The Al-Ándalus Project S Llorente-Romero, M Herrador-Colmenero, P Acosta-Manzano, ... Biomedicines 12 (4), 829 , 2024 2024 Citations: 1
Supervised land-and water-based exercise intervention in women with fibromyalgia: CERT-based exercise study protocol of the al-Ándalus physical activity randomised controlled trial IC Álvarez-Gallardo, B Gavilán-Carrera, A Carbonell-Baeza, ... medRxiv, 2024.01. 24.24301515 , 2024 2024 Citations: 1
Prescribing statin therapy in physically (in) active individuals vs prescribing physical activity in statin-treated patients: A four-scenario practical approach B Gavilán-Carrera, A Soriano-Maldonado, JD Mediavilla-García, CJ Lavie, ... Pharmacological Research 197, 106962 , 2023 2023 Citations: 7
Effectiveness of land-and water-based exercise on fatigue and sleep quality in women with fibromyalgia: the al-Ándalus quasi-experimental study B Gavilán-Carrera, M Borges-Cosic, IC Álvarez-Gallardo, ... Archives of Physical Medicine and Rehabilitation 104 (11), 1775-1784 , 2023 2023 Citations: 13
No changes in body composition and adherence to the mediterranean diet after a 12-Week aerobic training intervention in women with systemic lupus erythematosus: the EJERCITA … B Gavilán-Carrera, A Ruiz-Cobo, FJ Amaro-Gahete, ... Nutrients 15 (20), 4424 , 2023 2023 Citations: 6
Sedentary time is associated with depressive symptoms and state anxiety in women with fibromyalgia. Could physical activity and fitness modify this association? The al-Ándalus … B Gavilán-Carrera, M Delgado-Fernández, E Sierra-Nieto, ... Disability and Rehabilitation 45 (20), 3303-3311 , 2023 2023 Citations: 9
AB0571 DO ADULT WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS REACH FITNESS STANDARDS FOR MAINTAINING PHYSICAL INDEPENDENCE IN LATER YEARS? ASSOCIATIONS WITH FATIGUE AT 2-YEAR FOLLOW-UP BG Carrera, AS Maldonado, JA Vargas-Hitos Annals of the Rheumatic Diseases 82, 1482-1483 , 2023 2023
Longitudinal association of sedentary time and physical activity with pain and quality of life in fibromyalgia B Gavilán‐Carrera, M Delgado‐Fernández, IC Álvarez‐Gallardo, ... Scandinavian Journal of Medicine & Science in Sports 33 (3), 292-306 , 2023 2023 Citations: 9
NET-RMDs study: networks of fatigue and pain in rheumatic and musculoskeletal diseases–protocol for an international cross-sectional study B Gavilán-Carrera, R Geenen, C Hughes, L Barbosa, M Visser, J McVeigh, ... BMJ open 12 (11), e061099 , 2022 2022 Citations: 3
Where does the time go? Displacement of device-measured sedentary time in effective sedentary behaviour interventions: systematic review and meta-analysis V Segura-Jimenez, SJH Biddle, K De Cocker, S Khan, B Gavilan-Carrera Sports Medicine 52 (9), 2177-2207 , 2022 2022 Citations: 25
MOST CITED SCHOLAR PUBLICATIONS
Physical and psychological paths toward less severe fibromyalgia: A structural equation model M Pulido-Martos, O Luque-Reca, V Segura-Jiménez, IC Alvarez-Gallardo, ... Annals of Physical and Rehabilitation Medicine 63 (1), 46-52 , 2020 2020 Citations: 66
Sedentary time, physical activity, and sleep quality in fibromyalgia: The al‐Ándalus project M Borges‐Cosic, VA Aparicio, F Estévez‐López, A Soriano‐Maldonado, ... Scandinavian Journal of Medicine & Science in Sports 29 (2), 266-274 , 2019 2019 Citations: 56
Effects of 12-week aerobic exercise on arterial stiffness, inflammation, and cardiorespiratory fitness in women with systemic LUPUS erythematosus: non-randomized controlled trial A Soriano-Maldonado, P Morillas-de-Laguno, JM Sabio, ... Journal of clinical medicine 7 (12), 477 , 2018 2018 Citations: 56
Do women with fibromyalgia present higher cardiovascular disease risk profile than healthy women? The al-Andalus project P Acosta-Manzano, V Segura-Jiménez, F Estévez-López, ... Clin Exp Rheumatol 35 (3), S61-S7 , 2017 2017 Citations: 43
Effects of 12-week aerobic exercise on patient-reported outcomes in women with systemic lupus erythematosus B Gavilán-Carrera, JA Vargas-Hitos, P Morillas-de-Laguno, ... Disability and Rehabilitation 44 (10), 1863-1871 , 2022 2022 Citations: 40
Assessment of muscle-strengthening exercise in public health surveillance for adults: A systematic review J Shakespear-Druery, K De Cocker, SJH Biddle, B Gavilán-Carrera, ... Preventive Medicine 148, 106566 , 2021 2021 Citations: 36
Association of physical fitness components and health-related quality of life in women with systemic lupus erythematosus with mild disease activity B Gavilán-Carrera, J Garcia da Silva, JA Vargas-Hitos, JM Sabio, ... PLoS One 14 (2), e0212436 , 2019 2019 Citations: 33
Substituting sedentary time with physical activity in fibromyalgia and the association with quality of life and impact of the disease: The al‐Ándalus Project B Gavilán‐Carrera, V Segura‐Jiménez, RA Mekary, M Borges‐Cosic, ... Arthritis care & research 71 (2), 281-289 , 2019 2019 Citations: 30
Objective and subjective measures of physical functioning in women with fibromyalgia: what type of measure is associated most clearly with subjective well-being? D Munguía-Izquierdo, M Pulido-Martos, FM Acosta, P Acosta-Manzano, ... Disability and Rehabilitation 43 (12), 1649-1656 , 2021 2021 Citations: 29
Association of objectively measured physical activity and sedentary time with health-related quality of life in women with fibromyalgia: The al-Ándalus project B Gavilán-Carrera, V Segura-Jiménez, F Estévez-López, ... Journal of Sport and Health Science 8 (3), 258-266 , 2019 2019 Citations: 27
Association of objectively measured physical activity and sedentary time with arterial stiffness in women with systemic lupus erythematosus with mild disease activity P Morillas-de-Laguno, JA Vargas-Hitos, A Rosales-Castillo, ... PLoS One 13 (4), e0196111 , 2018 2018 Citations: 27
Where does the time go? Displacement of device-measured sedentary time in effective sedentary behaviour interventions: systematic review and meta-analysis V Segura-Jimenez, SJH Biddle, K De Cocker, S Khan, B Gavilan-Carrera Sports Medicine 52 (9), 2177-2207 , 2022 2022 Citations: 25
Cardiorespiratory fitness and age‐related arterial stiffness in women with systemic lupus erythematosus C Montalbán‐Méndez, A Soriano‐Maldonado, JA Vargas‐Hitos, ... European Journal of Clinical Investigation 48 (3), e12885 , 2018 2018 Citations: 24
Emotional intelligence impairments in women with fibromyalgia: Associations with widespread pain O Luque-Reca, M Pulido-Martos, B Gavilán-Carrera, IC García-Rodríguez, ... Journal of Health Psychology 26 (11), 1901-1912 , 2021 2021 Citations: 23
Physical fitness and body composition in women with systemic lupus erythematosus S Sola-Rodríguez, B Gavilán-Carrera, JA Vargas-Hitos, JM Sabio, ... Medicina 55 (2), 57 , 2019 2019 Citations: 21
Patterns of sedentary time and quality of life in women with fibromyalgia: Cross-sectional study from the Al-ándalus project B Gavilán-Carrera, V Segura-Jiménez, P Acosta-Manzano, ... JMIR mHealth and uHealth 8 (3), e14538 , 2020 2020 Citations: 18
Interplay between genetics and lifestyle on pain susceptibility in women with fibromyalgia: the al-Andalus project F Estévez-Lopez, JM Guerrero-Gonzalez, D Salazar-Tortosa, ... Rheumatology 61 (8), 3180-3191 , 2022 2022 Citations: 16
Heart rate variability in women with systemic lupus erythematosus: association with health-related parameters and effects of aerobic exercise E Martínez-Rosales, S Sola-Rodríguez, JA Vargas-Hitos, ... International Journal of Environmental Research and Public Health 17 (24), 9501 , 2020 2020 Citations: 16
Sedentary time accumulated in bouts is positively associated with disease severity in fibromyalgia: the al-Ándalus project V Segura-Jiménez, B Gavilán-Carrera, P Acosta-Manzano, DB Cook, ... Journal of Clinical Medicine 9 (3), 733 , 2020 2020 Citations: 14
Effectiveness of land-and water-based exercise on fatigue and sleep quality in women with fibromyalgia: the al-Ándalus quasi-experimental study B Gavilán-Carrera, M Borges-Cosic, IC Álvarez-Gallardo, ... Archives of Physical Medicine and Rehabilitation 104 (11), 1775-1784 , 2023 2023 Citations: 13