Bhanu Pratap

@mangalayatan.in

Assistant Professor at Mangalayatan Institute of Pharmaceutical Education and Research
Mangalayatan university

Bhanu Pratap


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https://researchid.co/bhanupratap
1

Scopus Publications

19

Scholar Citations

2

Scholar h-index

1

Scholar i10-index

Scopus Publications

  • Formulation and Characterisation of Herbal Ethosomal Gel of Luliconazole and Clove Oil for Modified Drug Diffusion to the Skin
    Bhanu Pratap, Shamim Shamim, Shadab Ali
    Research Journal of Pharmacy and Technology, 2025
    The creation, characterisation, and optimisation of an herbal ethosomal formulation are all included in this work. The current study aims to create ethosomes filled with drugs and capped with Syzygium Aromaticum L., or clove oil. These ethosomes are then further mixed into Carbopol 934 K, which forms an ethosomal gel. The formulation aims to convey a fungal infection treatment that is successful. The medication (luliconazole), soy lecithin, clove extract, and propylene glycol were used in the formulation of the construct. Six ethosomal formulations with different constituent concentrations were processed in total to identify the best formulation out of the bunch. In addition, a number of assessment criteria, including the percent of entrapment efficiency, the size of the particle, zeta potential, and polydispersity index (PDI), were used to the generated drug-loaded ethosomes. By utilising transmission electron microscopy, the surface morphology was evaluated, while atomic force microscopy was used to get further in-depth information about the surface morphology. In order to study thermal behaviour for luliconazole, soya lecithin, clove extract, physical mixture, and optimised formulation (EF5), a thermal gravimetric analysis graph was produced. The ethosomal gel's viscosity, pH, Spreadability, and extrudability were calculated to assess the formulation's appropriateness for topical application. The entire study concludes that luliconazole can be delivered in an advanced, targeted, and sustained manner using this herbal ethosomal method. Because of its ideal soy lecithin dosage of 400mg and ethanol concentration of 30%, After analysis of the data, the ethosomal formulation EF5 was found to be the most optimal one. This results in a maximum entrapment efficiency of 88.56±0.74%. It was found that the optimal PDI, zeta potential, and vesicle size were 0.186±0.07, − 42.2±0.3mV, and 155.3±1.2nm, respectively. The best stable solutions were found to be ethosomal suspension and lyophilized ethosomal suspension at 4°C/60 ±5 RH. The whole study demonstrates that the combination of ethosomal formulation with luliconazole and clove extract has a synergistic effect and works well to treat fungal infection.

RECENT SCHOLAR PUBLICATIONS

  • Development and Evaluation of Licorice Root Extract-Based Cream for the Management of Hyperpigmentation
    S Rana, BPB Pratap, PS Jadaun
    Current Pharmaceutical Research, 384-392 , 2025
    2025
    Citations: 1
  • Hydrogel Microneedles: A Breakthrough in Disease Treatment and Drug Delivery Systems
    B Pratap, PS Jadaun
    Current Pharmaceutical Research, 60-77 , 2025
    2025
    Citations: 6
  • Formulation and Characterisation of Herbal Ethosomal Gel of Luliconazole and Clove Oil for Modified Drug Diffusion to the Skin
    B Pratap, S Shamim, S Ali
    Research Journal of Pharmacy and Technology 18 (8), 3501-3508 , 2025
    2025
    Citations: 12
  • ETHOSOMES AS AMPHIPHILIC VESICLES FOR MODIFIED DRUG DIFFUSION TO SKIN
    B Pratap, S Khan, S Ali
    2024

MOST CITED SCHOLAR PUBLICATIONS

  • Formulation and Characterisation of Herbal Ethosomal Gel of Luliconazole and Clove Oil for Modified Drug Diffusion to the Skin
    B Pratap, S Shamim, S Ali
    Research Journal of Pharmacy and Technology 18 (8), 3501-3508 , 2025
    2025
    Citations: 12
  • Hydrogel Microneedles: A Breakthrough in Disease Treatment and Drug Delivery Systems
    B Pratap, PS Jadaun
    Current Pharmaceutical Research, 60-77 , 2025
    2025
    Citations: 6
  • Development and Evaluation of Licorice Root Extract-Based Cream for the Management of Hyperpigmentation
    S Rana, BPB Pratap, PS Jadaun
    Current Pharmaceutical Research, 384-392 , 2025
    2025
    Citations: 1
  • ETHOSOMES AS AMPHIPHILIC VESICLES FOR MODIFIED DRUG DIFFUSION TO SKIN
    B Pratap, S Khan, S Ali
    2024