LAMP Integrated Paper Microfluidic DNA Diagnostic Platform for Rapid Detection of MRSA Ananya Tiwari, Saloni Malik, Malvika Shukla, Nidhi Yadav, Vaishnavi Newaskar, et al. Advanced Materials Technologies, 2026 Antimicrobial resistance (AMR) is a growing global health concern caused by the misuse of antibiotics in medicine, agriculture, and livestock. A major contributor to this crisis is methicillin‐resistant Staphylococcus aureus (MRSA), which makes treating common infections difficult. Traditional MRSA detection methods, like culture‐based tests and molecular assays, are often slow and expensive, restricting their use in on‐site diagnostics. To overcome these limitations, a novel paper‐based microfluidic platform has been developed for rapid and accurate MRSA detection. This platform integrates DNA isolation with loop‐mediated isothermal amplification (LAMP) and a vertical flow immunoassay (VFI), collectively termed PL‐VFI, to target the mecA gene specific to MRSA. Combining simplicity and precision, the device provides results within 1.5 hours without complex handling. It demonstrates high sensitivity and specificity with a detection limit of 10 1 CFU/ml (colony‐forming units per milliliter) and 1 fg (femtogram) DNA. Additionally, it successfully detects MRSA in clinical blood samples and offers a long shelf life, making it ideal for on‐site DNA diagnostics and resource‐limited settings.
Anti-inflammatory Potential of Pongamia pinnata: A Comprehensive Review on Molecular Mechanisms and Therapeutic Implications Bhumika Dudhatra, Kashyap Thummar, Jigna Vadalia, Vaibhav Bhatt Anti Inflammatory and Anti Allergy Agents in Medicinal Chemistry, 2026 Pongamia pinnata (L.) has long been used in both the Ayurvedic and Siddha systems of medicine. It belongs to the leguminous family and shows significant potential for antiinflammatory activity, further supported by growing pharmacological and mechanistic evidence. This paper discusses recent advances in the study of its phytochemistry and the molecular mechanisms underlying its anti-inflammatory effects. Flavonoids, furanoflavonoids, terpenoids, and sterols are the main bioactive compounds, which modulate key inflammatory pathways such as NFκB, COX-2, iNOS, and the expression of proinflammatory cytokines. Antioxidant, immunomodulatory, and membrane-stabilising activities help reduce oxidative stress and inflammation. Diseasespecific evidence highlights potential roles in arthritis, metabolic inflammation, neurodegeneration, and skin disorders. Emerging formulation approaches, including nanoparticles, ethosomes, and hydrogels, have improved the bioavailability, stability, and targeted delivery of various constituents of P. pinnata. Although preclinical studies have demonstrated a favourable safety profile, inadequate clinical validation and the need for standardised formulations remain two major barriers to therapeutic translation. This review aims to guide future research towards standardisation, pharmacokinetics, and formulation development to position P. pinnata as an attractive candidate for anti-inflammatory drug development.
Intelligent air pollution prediction algorithm-based optimized random forest regression for reducing asthmatic attacks Saif Saad Fakhrulddin, Vaibhav Bhatt, Sadik Kamel Gharghan Journal of Air Pollution and Health, 2025 Introduction: Air pollution can trigger the attack in asthmatic patients if uncontrolled. Previous works focused on controlling pollution by proposing algorithms to predict air pollution. While these prediction algorithms save patients from attack triggers, they have limitations such as prediction accuracy, mathematical complexity, and lack of adequate patient notification systems.Materials and methods: This study proposed a novel Intelligent Air Pollution Prediction (IAPP) algorithm based on optimizing Random Forest Regression (RFR) to predict air pollution and send an alert message to the patient and hospital in real time. Meanwhile, IAPP utilized reliable data from Internet of Things (IoT)-based air pollution detection nodes. The performance of IAPP was evaluated in a real-world environment during the peak pollutant season to test the prediction accuracy of air pollution.Results: Results showed that the proposed IAPP achieved a high prediction accuracy of 99.98% with an R-squared value of 0.99. This demonstrated that the IAPP algorithm based on the RFR model can effectively protect asthmatic patients from attack triggers.Conclusion: As a result, the IAPP algorithm reduces hospital visits during high pollution and enables patients to complete their daily activities without obstacles or absence.
First-principles quantum transport investigation of Fe-functionalized phosphorene for high-sensitivity NO2 detection P Kher, G Jadav, S Dodia, V Bhatt, D Katariya, R Khunt, DK Dhruv, ... Next Materials 12, 102064 , 2026 2026
Design, Synthesis, and Characterization of TEPE-Zn-MOF as a Turn-On Fluorescent Probe for Pb²⁺ Detection K Modi, D Kher, B Dhumale, N Patel, K Bhatt, CN Patel, V Bhatt, ... Journal of Fluorescence, 1-14 , 2026 2026
Anti-inflammatory Potential of Pongamia pinnata: A Comprehensive Review on Molecular Mechanisms and Therapeutic Implications. B Dudhatra, K Thummar, J Vadalia, V Bhatt Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry , 2026 2026 Citations: 1
LAMP Integrated Paper Microfluidic DNA Diagnostic Platform for Rapid Detection of MRSA A Tiwari, S Malik, M Shukla, N Yadav, V Newaskar, M Raval, D Maiya, ... Advanced Materials Technologies 11 (3), e00346 , 2026 2026
Promoting Sustainable Cultural Exchange and Education in Himalayan Tourism Destination: Current Practices and Future Directions S Mishra, V Bhatt, S Bhartiya Himalayan Mountain Tourism, 347-362 , 2026 2026
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR STABILITY-INDICATING ANALYSIS OF FLURALANER AND PROCESS-RELATED IMPURITIES IN DRUG SUBSTANCE R Watpade, C Dholakia, K Singh, V Bhatt, K Nimbalkar, H Shah Nirma University Journal of Pharmaceutical Sciences 12 (2), 19-38 , 2025 2025
Plant-Based Approach for Nutrient Enhancement and Quality Assurance in Food MN Kher, A Warghane, SP Dholakia, VV Shah, VD Bhatt Sustainable Food Fortification: Biobased Approaches and Strategies, 197-216 , 2025 2025
Evaluating the impact of natural fertilizers on growth dynamics and yield performance of Solanum melongena L. A Warghane, J Thakkar, K Chauhan, D Zala, H Patel, V Bhatt, ... Frontiers in Sustainable Food Systems 9, 1668080 , 2025 2025
Comparative Analysis of Microbial Diversity in the Soil Rhizosphere and Root Endosphere of Sorghum bicolor across Various Regions of Gujarat, India B Rajguru, H Bodgamwala, B Bhatt, M Shri, VD Bhatt Microbiology 94 (5), 791-803 , 2025 2025
Synthesis, characterization, and biological studies of novel organometallic compounds of Re (I) with substituted (E)-2-(2-benzylidenehydrazinyl)-3-nitropyridine AD Padariya, NK Savaliya, HM Parekh, BS Bhatt, VD Bhatt, MN Patel Journal of Molecular Structure, 144146 , 2025 2025 Citations: 1
Heteroleptic N, N donor carbonitrile based Au (III) complexes: DNA/BSA interaction studies, Molecular Docking, and cytotoxicity studies NJ Patel, RA Dabhi, MP Dhaduk, NK Savaliya, BS Bhatt, MV Lunagariya, ... Journal of Trace Elements in Medicine and Biology, 127747 , 2025 2025
Mycobacteriophage D29: A tool for TB diagnosis R Ughreja, S Shah, V Bhatt International Journal of Pharmaceutical Sciences and Nanotechnology (IJPSN … , 2025 2025
A DFT Investigation of Halogen-Substituted Indeno[1,2- b ]quinoxaline–Oxazole Derivatives: Insights into Electronic Structure and Reactivity D Katariya, G Jadav, P Shah, U Patel, P Unjiya, V Rathod, D Desani, ... Russian Journal of Organic Chemistry 61 (8), 1549-1558 , 2025 2025 Citations: 1
Impact of salt-induced chemo-signal on rhizomicrobiome-plant interaction M Thakar, B Rajguru, J Thakkar, V Bhatt, M Shri, A Warghane Journal of Crop Health 77 (4), 131 , 2025 2025 Citations: 4
Biological and computational studies of organometallic compounds of rhenium (I) with substituted phenyl (2-(thiazol-4-yl)-1H-benzo [d] imidazol-1-yl) methanone AD Padariya, NK Savaliya, HM Parekh, BS Bhatt, VD Bhatt, MN Patel Journal of Organometallic Chemistry 1036, 123708 , 2025 2025
Porous Microspheres: Synthesis, Characterization, and Applications in Modern Science RA Ughreja, SR Shah, VD Bhatt, DR Bhimani, RB Panchmatia, ... Journal of Integrated Health Sciences 13 (2), 108-114 , 2025 2025
Non-destructive Mathematical Modeling Techniques for Fruit Volume Estimation: A Systematic Review and Meta-analysis. N Rani, K Bamel, S Garg, RA Nath, I Mishra, V Bhatt, S Gupta Indian Journal of Agricultural Research 59 (7) , 2025 2025
Influence of pyridine entangled novel hybrid quinoxaline spirane on the fluorescence and absorption spectra of biomolecules: molecular docking, pharmacokinetic, and in-vitro … RA Dabhi, MP Dhaduk, NK Savaliya, AD Padariya, AP Patil, RA Desai, ... Journal of Fluorescence 35 (7), 6079-6096 , 2025 2025 Citations: 4
Subclinical Vascular Dysfunction in Mothers of Children with Anorectal Malformations: A Multiomics Study A Kaloni, RS Joshi, J Ramji, S Vasa, S Samantaray, K Sharma, V Bhatt, ... medRxiv, 2025.06. 29.25330492 , 2025 2025
Synthesis, Characterization, and Biological Studies of Organometallic Compounds of Re (I) with 2‐(5‐(4‐Nitrophenyl)‐3‐phenyl‐4, 5‐dihydro‐1H‐pyrazol‐1‐yl) benzo [d] thiazole … AD Padariya, NK Savaliya, HM Parekh, BS Bhatt, VD Bhatt, MN Patel ChemistrySelect 10 (21), e02109 , 2025 2025
Encyclopedia of marine biotechnology SK Kim John Wiley & Sons , 2020 2020 Citations: 115
Genome sequence of salt-tolerant Bacillus safensis strain VK, isolated from saline desert area of Gujarat, India VV Kothari, RK Kothari, CR Kothari, VD Bhatt, NM Nathani, PG Koringa, ... Genome Announcements 1 (5), 10.1128/genomea. 00671-13 , 2013 2013 Citations: 74
Molecular analysis of the bacterial microbiome in the forestomach fluid from the dromedary camel (C amelus dromedarius ) VD Bhatt, SS Dande, NV Patil, CG Joshi Molecular biology reports 40 (4), 3363-3371 , 2013 2013 Citations: 70
In Vitro Antibacterial Evaluation of Terminalia chebula as an Alternative of Antibiotics against Bovine Subclinical Mastitis MN Kher, NR Sheth, VD Bhatt Animal biotechnology 30 (2), 151-158 , 2019 2019 Citations: 66
Identification and antibiogram of microbes associated with bovine mastitis VD Bhatt, MS Patel, CG Joshi, A Kunjadia Animal biotechnology 22 (3), 163-169 , 2011 2011 Citations: 56
Lung cancer targeting efficiency of Silibinin loaded Poly Caprolactone /Pluronic F68 Inhalable nanoparticles: In vitro and In vivo study P Patel, M Raval, A Manvar, V Airao, V Bhatt, P Shah PLoS One 17 (5), e0267257 , 2022 2022 Citations: 50
Whole-genome shotgun sequencing of an Indian-origin Lactobacillus helveticus strain, MTCC 5463, with probiotic potential JB Prajapati, CD Khedkar, J Chitra, S Suja, V Mishra, V Sreeja, RK Patel, ... Journal of bacteriology 193 (16), 4282-4283 , 2011 2011 Citations: 48
Novel silibinin loaded chitosan-coated PLGA/PCL nanoparticles based inhalation formulations with improved cytotoxicity and bioavailability for lung cancer M Raval, P Patel, V Airao, V Bhatt, N Sheth Bionanoscience 11 (1), 67-83 , 2021 2021 Citations: 44
The landscape of alternative splicing in buccal mucosa squamous cell carcinoma TM Shah, AK Patel, VD Bhatt, AK Tripathi, S Shah, V Shankar, CG Joshi Oral oncology 49 (6), 604-610 , 2013 2013 Citations: 43
A review on touch DNA collection, extraction, amplification, analysis and determination of phenotype PH Nimbkar, VD Bhatt Forensic science international 336, 111352 , 2022 2022 Citations: 42
Exploring microbial diversity in the rhizosphere: a comprehensive review of metagenomic approaches and their applications B Rajguru, M Shri, VD Bhatt 3 Biotech 14 (10), 224 , 2024 2024 Citations: 36
Evaluation of a topical herbal drug for its in-vivo immunomodulatory effect on cytokines production and antibacterial activity in bovine subclinical mastitis VD Bhatt, TM Shah, DS Nauriyal, AP Kunjadia, CG Joshi AYU (An International Quarterly Journal of Research in Ayurveda) 35 (2), 198-205 , 2014 2014 Citations: 35
Metagenomic analysis of buffalo rumen microbiome: effect of roughage diet on Dormancy and Sporulation genes KM Singh, B Reddy, AK Patel, H Panchasara, N Parmar, AB Patel, ... Meta Gene 2, 252-268 , 2014 2014 Citations: 30
Unveiling the green dialogue: advancements in omics technologies for deciphering plant–microbe interactions in soil P Bhimani, P Mahavar, B Rajguru, VD Bhatt, NM Nathani, M Shri Discover Plants 1 (1), 4 , 2024 2024 Citations: 29
Synthetic approach toward spiro quinoxaline-β-lactam based heterocyclic compounds: Spectral characterization, SAR, pharmacokinetic and biomolecular interaction studies RA Dabhi, MP Dhaduk, VD Bhatt, BS Bhatt Journal of Biomolecular Structure and Dynamics 41 (12), 5382-5398 , 2023 2023 Citations: 28
Identification of novel transcripts deregulated in buccal cancer by RNA-seq MR Sajnani, AK Patel, VD Bhatt, AK Tripathi, VB Ahir, V Shankar, S Shah, ... Gene 507 (2), 152-158 , 2012 2012 Citations: 28
Transcriptome analysis of the adult rumen fluke Paramphistomum cervi following next generation sequencing V Choudhary, S Garg, R Chourasia, JJ Hasnani, PV Patel, TM Shah, ... Gene 570 (1), 64-70 , 2015 2015 Citations: 24
Lycopene loaded polymeric nanoparticles for prostate cancer treatment: Formulation, optimization using Box-behnken design and cytotoxicity studies A Goswami, N Patel, V Bhatt, M Raval, M Kundariya, N Sheth Journal of Drug Delivery Science and Technology 67, 102930 , 2022 2022 Citations: 23