Dr.Biswajit Panda
@citycollegekolkata.org
Assistant Professor, Department of Chemistry
City College, Kolkata
RESEARCH INTERESTS
Organic Chemistry, Organometallic Chemistry
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Biswajit Panda
Bentham Science Publishers Ltd.
Abstract: Organocatalysis is an important and rapidly growing area for the synthesis of various organic molecules. Because of the inherent non-metal properties, mild reaction conditions, and broad functional group tolerance, the use of small organic compounds encoding and converting another organic component has developed into a remarkable process. C–H activation reactions, on the other hand, have already emerged as a powerful strategy for forming C–C and C–X (X= N, O, S) bonds. Combining organocatalysis and C-H bond functionalization is highly rational as two coexisting and rapidly growing research fields in modern synthetic chemistry, and the cooperative strength along this consistent has proven to be a successful way of making C-H bond functionalization much more feasible, reliable, and specific. At the same time, the synthesis of heterocyclic compounds is an important field in organic chemistry due to the vast application of heterocycles in pharmaceuticals, polymers, and material science. This mini-review describes the recent developments in the synthesis of heterocyclic compounds through the alliance of organocatalysis and C-H bond functionalizations.
Biswajit Panda
ARKAT USA, Inc.
Activation of carbon-nitrogen sigma bonds has attracted significant attention in recent years as a promising approach for bond-breaking and bond-making with a wide range of applications. Although C-N bonds are inert, due to their high bond energy, breaking them is feasible in the presence of a suitable catalyst. This approach has been successfully applied to numerous reactions, including cross-coupling reactions, making it a popular choice in the field of organic synthesis. Among the cross-coupling reactions, the alkynylation reaction occupies a significant position since alkynes are one of the privileged intermediates for the synthesis of foremost molecules with great importance in biology, medicine, and material science. This mini-review described the developments of various efficient strategies for the alkynylation reactions through the catalytic cleavage of both C(sp 2 ) – N and C(sp 3 ) – N bonds with mechanistic insights.
Biswajit Panda
Bentham Science Publishers Ltd.
Abstract: Nanoparticles have been proven to be efficient catalysts for a variety of chemical reactions, with added advantages such as the reuse of catalysts, increasing the scale of reactions employing continuous flow techniques, and simple separation of the reaction milieu, making them green, efficient, and lucrative choices. Over the last decade, gold nanoparticles (AuNPs) have appeared as promising and efficient catalysts in the field of sustainable organic synthesis.On the other hand, heterocycles are significant scaffolds in a variety of natural products and other biologically active molecules, as well as useful compounds for organic and material chemistry. Therefore, the progress of proficient techniques for the synthesis of heterocyclic compounds is always of major significance. This mini-review focuses on some of the most important AuNPs catalyzed heterocyclic compound synthesis processes. Wherever essential, the exclusivity of the approaches has been discussed by emphasizing substrate diversity, selectivity, product yields, and mechanistic features.
Biswajit Panda and Gianluigi Albano
MDPI AG
In the context of naturally occurring nitrogen heterocycles, nicotine is a chiral alkaloid present in tobacco plants, which can target and stimulate nicotinic acetylcholine receptors (nAChRs), a class of ligand-gated ion channels commonly located throughout the human brain. Due to its well-known toxicity for humans, there is considerable interest in the development of synthetic analogues; in particular, conformationally restricted analogues of nicotine have emerged as promising drug molecules for selective nAChR-targeting ligands. In the present mini-review, we will describe the synthesis of the conformationally restricted analogues of nicotine involving one or more catalytic processes. In particular, we will follow a systematic approach as a function of the heteroarene structure, considering: (a) 2,3-annulated tricyclic derivatives; (b) 3,4-annulated tricyclic derivatives; (c) tetracyclic derivatives; and (d) other polycyclic derivatives. For each of them we will also consider, when carried out, biological studies on their activity for specific nAChR subunits.
Biswajit Panda and Gianluigi Albano
MDPI AG
Transition metal-catalyzed carbonylation reactions have emerged as one of the most relevant synthetic approaches for the preparation of carbonyl-containing molecules. The most commonly used protocol for the insertion of a carbonyl moiety is the use of carbon monoxide (CO) but, due to its toxic and explosive nature, this process is not suitable at an industrial scale. More recently, the chemistry of CO surrogates has received large attention as a way to use less expensive and more environmentally friendly methods. Among the various CO surrogates, N,N-dimethylformamide (DMF) has been paid greater attention due to its low cost and easy availability. This mini-review gives appealing insights into the application of DMF as a CO surrogate in metal-catalyzed carbonylations; in particular, in the first part we will give a general state of the art of these reactions for the preparation of carbonyl-containing molecules; then, we will take into account all the various synthetic approaches for the metal-catalyzed carbonylative synthesis of heterocycles using DMF as a CO surrogate. Each protocol has been discussed critically in order to screen the best synthetic method and to offer perspective on trends and future directions in this field.
Biswajit Panda and Amal Kumar Gooyee
Bentham Science Publishers Ltd.
Oceans can play a major role in supplying life-saving medicines to the world. Although considerable progress has been made in finding new medicines from marine sources, great efforts are still necessary to examine such molecules for clinical applications. Xyloketals are an important group of natural products with various powerful and prominent bioactivities such as inhibition of acetylcholine esterase, antioxidant activity, inhibition of L-calcium channels, radical-scavenging behavior, suppression of cell proliferation, reduction of neonatal hypoxic-ischemic brain injury, etc. This review describes the isolation and structural characterization of all xyloketal natural products giving major emphasis on their bioactivity.
Biswajit Panda
ARKAT USA, Inc.
Jian-Jhih Peng, Biswajit Panda, Kamani Satyanarayana, Hau-Ren Yang, Shou-Ling Huang, Mao Jung Huang, Chun-hsien Chen, Guoqiao Lai, Yu-Ying Lai, and Tien-Yau Luh
American Chemical Society (ACS)
A first-generation Grubbs catalyst has been shown to not only catalyze the ring opening metathesis polymerization (ROMP) of cyclopropene derivatives but also differentiate E- and Z-double bonds in intermediates by different reaction patterns, leading to stereospecific synthesis of poly(methylene-E-vinylene). The intermediate with the Z-double bond formed during the course of ROMP of cyclopropene is sensed by the catalyst, chopped by the catalyst, and removed as the cyclohexadiene derivative, and in the meantime, a ruthenium–carbene species is regenerated for continuing polymerization. When a second-generation Grubbs catalyst is used, a cyclic polymer with all double bonds in the trans configuration is obtained as the sole polymeric product, in addition to the same cyclohexadiene derivative as described above. The degree of polymerization in the latter reaction is independent of the loading of the catalyst. The formation of cyclic polymer is not common and the mechanism thereof remains unclear. One possibi...
Biswajit Panda
ARKAT USA, Inc.
Abstract Bruguierols are an unusual class of natural products exhibiting interesting biological activities like antibacterial activity against both Gram-positive and Gram-negative bacteria including mycobacteria and resistant strains. A considerable number of reports have appeared in the literature dealing with the synthesis and biological activity of bruguierols which asks for a comprehensive review on this topic. Here, the joy and challenges of all synthetic strategies to construct these molecules including comparative studies of diversified approaches and, wherever required, the beauty and uniqueness of the respective synthetic strategy are thoroughly being discussed.
Biswajit Panda
Wiley
Abhishek Dhar, Abhishek Dutta, Pushan Sharma, Biswajit Panda, and Subhasis Roy
Informa UK Limited
ABSTRACT In the present work, first, the reference catalyst super acidic nanostructured sulfated zirconia (SZ) and super acidic nanostructured aluminum chloride impregnated sulfated zirconium oxides in mole ratios of Zr4+:Al3+ as 2:1 (ACSZ-1), 1:1 (ACSZ-2), and 1:2 (ACSZ-3) were synthesized by a simple precipitation method. The catalytic performance of these four catalysts were evaluated during the isomerization of n-hexane, n-heptane, and n-octane to their corresponding branched chain isomers at low temperature and pressure conditions. ACSZ-2 shows high activity toward isomerization of n-hexane, n-heptane, and n-octane into their corresponding branched chain isomers. The reference catalyst SZ was proved to be less effective compare to the other three synthesized ACSZ catalysts. Ammonia-temperature-programmed desorption of these two materials ensures that the super acidity of ACSZ-2 is higher than that of SZ. Atomic force microscopic and scanning electron microscopic pictures predict the nature of the surface of the catalysts. Transmission electron micrographic analysis indicates the presence of particle-bulks having average size 12–20 nm, presenting an amorphous nature and having no definite surface morphology of ACSZ-2. Fourier transform infrared provides an outline regarding different linkages and bond connectivities between atoms and groups in ACSZ-2 and SZ. After catalyst evaluation and characterization a probable reaction mechanism has been proposed theoretically. The reactivity and selectivity of ACSZ-2 and SZ as well as the order and activation energy of the isomerization reactions in presence of ACSZ-2 have been calculated. The use of ACSZ-2 is beneficial from the point of cost efficiency as well as its use is energy saving.
Tarun Sarkar and Biswajit Panda
Georg Thieme Verlag KG
Tarun Sarkar and Biswajit Panda
Georg Thieme Verlag KG
Two different strategies have been developed to perform the gold-catalyzed benzannulation of both electron-rich pyridine containing oxoalkynes with electron-rich alkynes as well as electron-deficient pyridine containing oxoalkynes with electron-deficient alkynes. The benzannulation between electron-rich oxoalkynes with electron-rich alkynes proceeds in the presence of highly electron-deficient gold catalysts, whereas using catalytic amount of alcohol benzannulation was performed efficiently between electron-deficient oxoalkynes with electron-deficient alkynes.
Biswajit Panda and Tarun K. Sarkar
American Chemical Society (ACS)
A new and efficient one-pot desilylation-gold-catalyzed cycloisomerization of alkynes containing a silyl-protected phenolic -OH and a free alcoholic -OH unit leads selectively to the formation of tetrahydrofuranobenzopyran ring system. This approach has been used for the regio- and stereoselective synthesis of xyloketal D, xyloketal G, and the related natural product alboatrin.
Tarun Sarkar and Biswajit Panda
Georg Thieme Verlag KG
A highly efficient gold and palladium combined methodology for the Sonogashira coupling of a wide array of electronically and structurally diverse aryl and heteroaryl halides is described. The orthogonal reactivity of the two metals shows high selectivity and extreme functional group tolerance in Sonogashira coupling. A brief mechanistic study reveals that the gold acetylide intermediate enters into the palladium catalytic cycle at the transmetalation step.
Tarun Sarkar, Biswajit Panda, and Jhuma Bhadra
Georg Thieme Verlag KG
The AuCl 3 -catalyzed benzannulation of pyridine-containing oxo-alkynes with external as well as internal alkynes proceeds under mild conditions, and a variety of quinoline and isoquinoline derivatives are produced in good to excellent yields. The reaction proceeds through the formation of aza-isobenzopyrylium auric ate complexes as evident from trapping experiments.
Biswajit Panda and Tarun K. Sarkar
Elsevier BV
Biswajit Panda and Tarun K. Sarkar
Royal Society of Chemistry (RSC)
The Sonogashira-type cross-coupling of arenediazonium salts is reported for the first time using a Pd-Au dual catalytic system.
Biswajit Panda, Sankar Basak, Anindya Hazra, and Tarun K. Sarkar
SAGE Publications
A domino Michael–Dieckmann–Peterson approach to the synthesis of functionalised hydroxyquinolines and hydroxyisoquinolines is described.
Biswajit Panda and Tarun K. Sarkar
Elsevier BV