SREENIVASA CHARAN ARCHAKAM

@spsp.ac.in

Head-Department of Pharmaceutical Analysis
SRI PADMAVATHI SCHOOL OF PHARMACY

EDUCATION

Ph.D In Pharmaceutical Sciences

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmaceutical Science, Analytical Chemistry, Spectroscopy, Drug Discovery
9

Scopus Publications

130

Scholar Citations

5

Scholar h-index

4

Scholar i10-index

Scopus Publications

  • Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in Commercial Formulation by Multitudinal UV and Multivariate FT-IR Spectroscopic Methods
    Sreenivasa Charan Archakam, Keerthisikha Palur, Rajitha Galla, Sai Sucharitha Padiri, Praveen Kumar Tulasi, Ranganayakulu Diviti
    Indian Journal of Pharmaceutical Education and Research, 2024
    Aim In the current study, a multivariate FTIR method and two different UV spectrophotometric methods were employed for the simultaneous determination of Amitriptyline Hydrochloride (ATH) and Propranolol Hydrochloride (PPH) in their combined formulation. Materials and Methods The multivariate FTIR method based on the use of Classical Least Squares (CLS) was developed and executed in the lab solutions software for the simultaneous determination of ATH and PPH. CLS model was performed in the wavenumber range of 2550.04-3600.12 cm-1 and 969.64-1757 cm-1. In addition, two UV spectroscopic methods, namely absorbance correction method and crammer’s matrix method were developed and validated in the concentration ranges of 2-10μg/mL and 5-55μg/mL for ATH and PPH respectively. Results The statistical parameters obtained from the applied multivariate FTIR-CLS model revealed the model accuracy and the assay results of ATH and PPH were found to be 92.32 (%w/w) and 97.35 (%w/w) respectively. The developed UV spectroscopic methods were validated as per ICH guidelines and all the validation parameters were found to be within the acceptance criteria. Conclusion The methods employed in the current study were found to simple, economical, accurate and do not require any prior separation.
  • Development and Validation of Chemometric Assisted UV Methods for the Simultaneous Determination of Ambroxol Hydrochloride, Terbutaline Sulphate and Guaiphenesin in Pharmaceutical Dosage Form
    Keerthisikha Palur, Sreenivasa Charan Archakam, Bharathi Koganti
    Indian Journal of Pharmaceutical Education and Research, 2023
    Abstract: Aim: The present study aimed to develop and validate chemometric assisted UVspectrophotometric methods for the simultaneous determination of ambroxol hydrochloride (ABH), terbutaline sulphate (TES) and guaiphenesin (GPN) in their combined dosage form. Materials and Methods: The two chemometric models applied for the UV spectroscopic data were principal component regression (PCR) and partial least squares regression (PLS). Standard mixture solutions containing different ratios of ABH, TES and GPN in the calibration ranges of 5-30 μg/mL, 25-125 μg/mL and 15-75 μg/mL respectively were prepared and their UV absorption spectra was recorded. Calibration data set and validation data set comprising of thirteen and nine standard mixture solutions respectively were constructed and computations were made using UNSCRAMBLER X version 10.0 software for both the models in the wavelength region of 240-310 nm. Results: The results obtained by the optimized chemometric calibration models depicted the accuracy of the models and the assay results of PCR and PLS for the quantification of ABH, TES and GPN in the syrup dosage form were found to be within the acceptance criteria. Conclusion: The developed PCR and PLS models were found to simple, economical, accurate and do not require any separation process. Keywords: Chemometric models, Principal component regression, Partial least squares regression, Ambroxol hydrochloride, Terbutaline sulphate, Guaiphenesin.
  • Development and Validation of Chemometric Assisted UV Spectroscopic Methods for the Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in Marketed Formulation
    KEERTHISIKHA PALUR, SREENIVASA CHARAN ARCHAKAM, PRIYANKA PATAKAM, KAVYA ORUPALLI, PADMAJA YADAVALI, YOGESWAR POTHAPALA, RANGANAYAKULU DIVITI
    Asian Journal of Chemistry, 2023
    The present work discusses the development and validation of chemometric assisted UV spectroscopic methods for analyzing two drugs amitriptyline hydrochloride and propranolol hydrochloride in their marketed formulation. The developed methods are two prominent chemometric models namely, principal component regression (PCR) and partial least squares regression (PLS) on which several research articles have been published for their immense contribution in the quantification of multi-component formulations. Linearity of the UV spectroscopic method was in the concentration ranges of 3-15 μg/mL of amitriptyline hydrochloride and 5-45 μg/mL of propranolol hydrochloride. The PCR and PLS chemometric models were established by employing fourteen mixtures as a calibration set and five mixtures as a validation set and were executed in the wavelength range of 240-320 nm with data interval of 5 nm. The statistical parameters obtained from both the methods revealed their validity and hence allows their suitability for analysis in regular quality control laboratories.
  • Chemometric assisted UV spectrophotometric and RP-HPLC methods for simultaneous determination of paracetamol, diphenhydramine, caffeine and phenylephrine in tablet dosage form
    Keerthisikha Palur, Sreenivasa Charan Archakam, Bharathi Koganti
    Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, 2020
  • Chemometric-assisted RP-HPLC method for the simultaneous determination of ambroxol hydrochloride, terbutaline sulfate,and guaiphenesin in combined dosage form
    Keerthisikha Palur, Bharathi Koganti, S. C. Archakam
    Journal of Applied Pharmaceutical Science, 2019
    An isocratic reverse phase HPLC method using chemometric model was developed and validated for the simultaneous determination of Ambroxol hydrochloride, Terbutaline sulfate and Guaiphenesin in their combined dosage form. Central composite design which is a subset of Response surface Methodology was used as the chemometric model. The separation of three drugs was carried out by using Phenomenex C18 column and detection at 220 nm using UV detector. Based on initial trials, the three factors selected for the design were Methanol (MN) concentration, Mobile phase pH and flow rate in the range of 55-65% (v/v), 4-5 units and 0.6-1 ml/min respectively. The impact of the selected factors on the responses like retention time of first peak (tR1), resolution of 2nd and 3rd peak (Rs2,3) and theoretical plates of first peak (TP1) were evaluated. Derringers’ desirability function was used to optimize the responses. The conditions which were optimized for the assay of drugs were MN, ACN, 50 mM KH2PO4 (pH 5) in the ratio of 55:10:35 at a flow rate of 0.8 ml/min. The developed and optimized method was validated as per the ICH guidelines and can be used for routine analysis in quality control laboratories.
  • Development and validation of chemometric assisted analytical methods for simultaneous estimation of atorvastatin calcium and Aspirin in capsule dosage form
    Keerthisikha Palur, BharathiKoganti, Sreenivasa Charan Archakam
    International Journal of Research in Pharmaceutical Sciences, 2019
    To develop two Chemometric-assisted analytical methods like UV spectrophotometry and RP-HPLC methods for the quantification of Atorvastatin calcium (ASC) and Aspirin (APN) in the capsule dosage form. Chemometric models used in UV spectrophotometry were Principal component regression model (PCRM) and Partial least-square regression (PLSR). Both the models were applied for the drugs in the calibration ranges of 4-20 and 30-150 μg/mL for ASC and APN respectively. Total of nineteen laboratory prepared mixtures were used for calibration and prediction set of the models. In addition, RP-HPLC method by using chemometric approach for was developed using C18 column at room temperature with a mobile phase of acetonitrile: methanol: triethylamine (53.1:11.9:35 v/v/v), pH- 3.0, with detection at 275 nm. PCRM and PLSR models were evaluated by statistical parameters and RP-HPLC method was optimized by using Response surface methodology. The developed methods like UV and RP-HPLC by using chemometrics showed almost similar results and both the methods can be used for their analysis.
  • New stability indicating RP-HPLC method for the simultaneous estimation of terbutaline sulphate and bromhexine hydrochloride in tablet dosage form
    Sreenivasa Charan Archakam, Sridhar Chenchugari, Chandrasekhar Kothapalli Bannoth
    International Journal of Research in Pharmaceutical Sciences, 2018
    Bromhexine hydrochloride is a mucolytic agent and is used in the treatment of respiratory disorders marketed in combination with Terbutaline Sulphate, which is used as a β2 – adrenergic receptor agonist and as a fast–acting bronchodilator. A stability indicating RP- HPLC method was developed for the simultaneous estimation of Terbutaline Sulphate and Bromhexine Hydrochloride in Tablet dosage form. A Shimadzu Prominence liquid chromatograph with LC-20AT pumping system and SPD-20A UV-Vis Detector was used for the proposed method. The chromatography was performed in reverse phase mode using a Phenomenex Luna C18 column (4.5 x 150 mm, 5µm) as stationary phase and isocratic mobile phase constituting of 0.1% v/v Perchloric acid: Acetonitrile (60:40) at a flow rate of 1.5 ml/ min with UV detection at 254 nm. The developed RP- HPLC method demonstrated good linearity in the concentration range of 10-60µg/ ml for Terbutaline Sulphate with R2=0.9991 and 20-100µg/ ml for Bromhexine Hydrochloride with R2=0.9992. Retention time of Terbutaline Sulphate was found to be around 2.1 min and for Bromhexine Hydrochloride it was found to be around 8.0 min. The precision, accuracy and robustness results were found to be satisfactory and within the limits. The assay was found to be 96.7%(w/w) for Terbutaline sulphate and 97.7%(w/w) for Bromhexine Hydrochloride. Specificity experiments revealed the absence of interference from mobile phase. The forced degradation studies like acidic, alkaline, oxidation and thermal degradation studies were performed and the degradation products were not interfering with the retention times of both the drugs. Thus, the proposed method could be used in the analysis of both the drugs in tablet dosage form.
  • Development and validation of a new stability indicating reversed-phase high-performance liquid chromatography method for the simultaneous estimation of tegafur and uracil in capsule dosage form
    Asian Journal of Pharmaceutics, 2018
  • Simultaneous estimation of atorvastatin and aspirin in bulk and capsule dosage form by chemometric assisted spectrophotometric methods
    Keerthisikha Palur, Bharathi Koganti, Sreenivasa Charan Archakam, Sridhar Chenchugari, Bhavana Nagireddy, Mahesh Babu Devabhaktuni, Meenakshi Sankranthi
    Journal of Young Pharmacists, 2016
    Objective: To develop the UV-spectrophotometric method and to apply the Chemometric designs to the developed method for the simultaneous estimation of Atorvastatin calcium (ATR) and Aspirin (ASP) in intact capsule dosage form without further extraction. Methods: The UV-Spectrophotometric method was developed by using methanol as solvent for both the drugs and the data generated from the absorption spectra was mined by two Chemometric designs which were based on the principles of linear regression analysis method (LRC) and Crammer’s matrix method (CRM). The wavelengths selected for linear regression analysis and crammers’matrix methods were 245 nm (wavelength of maximum absorption; λ max of ATR) and 275 nm (wavelength of maximum absorption; λ max of ASP). Results: Both the methods hold good linearity for ATR from 4-20 μg/ml and for ASP from 20-120 μg/ml with regression coefficient values of 0.9999 and 0.9991 respectively. The intraday and inter-day precision was found to be less than 2% RSD. The percentage recovery was in the range of 100.1-102.65 for Atorvastatin calcium and 99.95-101.15 for Aspirin by both the methods. The percentage assay was found to be 102.52 for ATR and 98.9 for ASP by LRC method and 101.62 for ATR and 98.84 for ASP by CRM method. Conclusion: The developed methods neither require any cumbersome separation procedure nor complex derivatization procedures for the analysis of the two drugs and moreover they are effective in minimizing the errors in analysis, simple and economical. Key words: Chemometrics, Regression analysis, Cramer’s Matrix method, Atorvastatin, Aspirin.

RECENT SCHOLAR PUBLICATIONS

  • SIMULTANEOUS METHOD VALIDATION FOR THE ESTIMATION OF NIVOLUMAB AND CABOZANTINIB IN BULK AND PHARMACEUTICAL DOSAGE FORM BY RP-HPLC METHOD
    SC Archakam, K Palur, B Nagalakshmi, R Diviti
    World 5 (4) , 2026
    2026
  • Multivariate Ultraviolet Spectrophotometric Methods for the Simultaneous Analysis of Phenazone and Lidocaine in Ear Drops
    SC Archakam, K Palur, H Neelofar, SS Devarala
    Indian Journal of Pharmaceutical Sciences 86 (5), 1642-1651 , 2024
    2024
  • SIMULTANEOUS DETERMINATION OF CHLORPHENIRAMINE MALEATE AND PHENYLEPHRINE HYDROCHLORIDE IN LIQUID DOSAGE FORMS BY UV SPECTROSCOPIC METHODS
    N H, K Palur, SC Archakam, S Reddy C, M K, J Reddy K, H Priya K, ...
    African Journal of Biological Sciences 6 (8), 633-649 , 2024
    2024
  • Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in Commercial Formulation by Multitudinal UV and Multivariate FT-IR Spectroscopic Methods
    SC Archakam, K Palur, R Galla, SS Padiri, PK Tulasi, R Diviti
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH 58 (2), s552-s557 , 2024
    2024
  • Development and Validation of Chemometric Assisted UV Spectroscopic Methods for the Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in …
    RD K PALUR, SC ARCHAKAM, P PATAKAM, K ORUPALLI, P YADAVALI, Y POTHAPALA
    Asian Journal of Chemistry 35 (9), 2121-2124 , 2023
    2023
  • Development and Validation of Chemometric Assisted UV Methods for the Simultaneous Determination of Ambroxol Hydrochloride, Terbutaline Sulphate and Guaiphenesin in …
    K Palur, SC Archakam, B Koganti
    Indian Journal of Pharmaceutical Education & Research 57 (1) , 2023
    2023
    Citations: 1
  • Estimation of eugenol in different tulsi ayurvedic formulations by RP-HPLC method
    SC Archakam, K Palur, MK Yerragunta, B Kuruba Pujari
    IP International Journal of Comprehensive and Advanced Pharmacology 7 (1), 51-53 , 2022
    2022
    Citations: 3
  • Multivariate analytical methods for simultaneous estimation of Atenolol and Hydrochlorothiazide in bulk and tablet dosage form
    SC Archakam, K Palur, PK Arava
    IP International Journal of Comprehensive and Advanced Pharmacology 6 (4 … , 2021
    2021
    Citations: 2
  • Chemometric assisted UV spectrophotometric and RP-HPLC methods for simultaneous determination of paracetamol, diphenhydramine, caffeine and phenylephrine in tablet dosage form
    K Palur, SC Archakam, B Koganti
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 243, 118801 , 2020
    2020
    Citations: 68
  • Chemometric-assisted RP-HPLC method for the simultaneous determination of ambroxol hydrochloride, terbutaline sulfate, and guaiphenesin in combined dosage form
    K Palur, B Koganti, SC Archakam
    Journal of Applied Pharmaceutical Science 9 (9), 092-097 , 2019
    2019
    Citations: 10
  • Development and Validation of a New Stability Indicating Reversed-phase High‑Performance Liquid Chromatography Method for the Simultaneous Estimation of Tegafur and Uracil in …
    SC Archakam
    Asian Journal of Pharmaceutics (AJP) 12 (03), 221-227 , 2018
    2018
  • New stability indicating RP-HPLC method for the simultaneous estimation of terbutaline sulphate and bromhexine hydrochloride in tablet dosage form
    CKB Sreenivasa Charan Archakam, Sridhar Chenchugari
    International Journal of Research in Pharmaceutical Sciences 9 (3), 776-781 , 2018
    2018
  • Quantitative determination of N-Acetyl cysteine by RP-HPLC method in bulk and parenteral injection
    CKB Sreenivasa Charan Archakam, Sridhar Chenchugari
    Asian Journal of Pharmacy ad Pharmacology 4 (5), 702-705 , 2018
    2018
    Citations: 5
  • SIMULTANEOUS ESTIMATION OF ZOLPIDEM TARTRATE AND MELATONIN IN TABLET DOSAGE FORM BY UV SPECTROPHOTOMETRY AND RP-HPLC
    SCRD Keerthisikha Palur, Sreenivasa Charan Archakam, Hemavathi Bodagala
    European Journal of Biomedical AND Pharmaceutical sciences 4 (9), 462-470 , 2017
    2017
  • ESTIMATION OF NEFOPAM HYDROCHLORIDE IN BULK AND PARENTERAL DOSAGE FORM BY ZERO ORDER AND AREA UNDER THE CURVE UV SPECTROPHOTOMETRIC METHODS
    SC Archakam, S Chenchugari, CSK Banoth
    Journal of Global Trends in Pharmaceutical Sciences 8 (3), 4088-4095 , 2017
    2017
  • RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF PHENYLEPHRINE HYDROCHLORIDE AND CHLORPHENIRAMINE MALEATE IN PHARMACEUTICAL DOSAGE FORM
    RD Sreenivasa Charan Archakam, Keerthisikha Palur, Naveen Kumar Reddy ...
    Journal of Global Trends in Pharmaceutical Sciences 8 (3), 4122-4129 , 2017
    2017
  • Simultaneous Estimation of Atorvastatin and Aspirin in Bulk and Capsule Dosage Form by Chemometric Assisted Spectrophotometric Methods
    K Palur, B Koganti, SC Archakam, S Chenchugari, B Nagireddy, ...
    Journal of Young Pharmacists 8 (4), 424-429 , 2016
    2016
    Citations: 3
  • ANALYTICAL METHODS FOR THE RECENTLY APPROVED FDA NEW MOLECULAR ENTITIES – A REVIEW
    SC Archakam, S Chenchugari, CSK Banoth
    Journal of Comprehensive Pharmacy 3 (3), 70-82 , 2016
    2016
    Citations: 5
  • Bioanalytical method development and validation of rizatriptan in human plasma using LC–MS/MS method
    S Velusamy, VM Masimukku, S Chereddy, JK Jadapalli, K Palur, ...
    International journal of chemical and analytical science 4 (2), 108-114 , 2013
    2013
    Citations: 13
  • Quantitative estimation of Ceftibuten by RP-HPLC method in bulk and capsule dosage form
    SC Archakam, K Palur, SN Sarabu, RK Kumarachari, R Diviti, S Velusamy
    journal of pharmacy research 6 (4), 395-400 , 2013
    2013
    Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

  • Chemometric assisted UV spectrophotometric and RP-HPLC methods for simultaneous determination of paracetamol, diphenhydramine, caffeine and phenylephrine in tablet dosage form
    K Palur, SC Archakam, B Koganti
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 243, 118801 , 2020
    2020
    Citations: 68
  • RP-HPLC method for the estimation of ceftiofur hydrochloride in bulk form
    K Palur, SC Archakam, N Lingasani, R Diviti, RK Kumarachari, ...
    journal of pharmacy research 7 (3), 246-251 , 2013
    2013
    Citations: 16
  • Bioanalytical method development and validation of rizatriptan in human plasma using LC–MS/MS method
    S Velusamy, VM Masimukku, S Chereddy, JK Jadapalli, K Palur, ...
    International journal of chemical and analytical science 4 (2), 108-114 , 2013
    2013
    Citations: 13
  • Chemometric-assisted RP-HPLC method for the simultaneous determination of ambroxol hydrochloride, terbutaline sulfate, and guaiphenesin in combined dosage form
    K Palur, B Koganti, SC Archakam
    Journal of Applied Pharmaceutical Science 9 (9), 092-097 , 2019
    2019
    Citations: 10
  • Quantitative determination of N-Acetyl cysteine by RP-HPLC method in bulk and parenteral injection
    CKB Sreenivasa Charan Archakam, Sridhar Chenchugari
    Asian Journal of Pharmacy ad Pharmacology 4 (5), 702-705 , 2018
    2018
    Citations: 5
  • ANALYTICAL METHODS FOR THE RECENTLY APPROVED FDA NEW MOLECULAR ENTITIES – A REVIEW
    SC Archakam, S Chenchugari, CSK Banoth
    Journal of Comprehensive Pharmacy 3 (3), 70-82 , 2016
    2016
    Citations: 5
  • Estimation of eugenol in different tulsi ayurvedic formulations by RP-HPLC method
    SC Archakam, K Palur, MK Yerragunta, B Kuruba Pujari
    IP International Journal of Comprehensive and Advanced Pharmacology 7 (1), 51-53 , 2022
    2022
    Citations: 3
  • Simultaneous Estimation of Atorvastatin and Aspirin in Bulk and Capsule Dosage Form by Chemometric Assisted Spectrophotometric Methods
    K Palur, B Koganti, SC Archakam, S Chenchugari, B Nagireddy, ...
    Journal of Young Pharmacists 8 (4), 424-429 , 2016
    2016
    Citations: 3
  • Multivariate analytical methods for simultaneous estimation of Atenolol and Hydrochlorothiazide in bulk and tablet dosage form
    SC Archakam, K Palur, PK Arava
    IP International Journal of Comprehensive and Advanced Pharmacology 6 (4 … , 2021
    2021
    Citations: 2
  • Kinetic Spectrophotometric estimation of Tramadol hydrochloride in bulk, tablet and capsule dosage forms
    KK RajaSekhar, V Shankarananth, A Sreenivasa Charan, L NagaMallika, ...
    Journal of Pharmacy Research 4 (10), 3842-3844 , 2011
    2011
    Citations: 2
  • Development and Validation of Chemometric Assisted UV Methods for the Simultaneous Determination of Ambroxol Hydrochloride, Terbutaline Sulphate and Guaiphenesin in …
    K Palur, SC Archakam, B Koganti
    Indian Journal of Pharmaceutical Education & Research 57 (1) , 2023
    2023
    Citations: 1
  • Quantitative estimation of Ceftibuten by RP-HPLC method in bulk and capsule dosage form
    SC Archakam, K Palur, SN Sarabu, RK Kumarachari, R Diviti, S Velusamy
    journal of pharmacy research 6 (4), 395-400 , 2013
    2013
    Citations: 1
  • Spectrophotometric method for the estimation of zidovudine in bulk, tablet and capsule dosage forms
    U Rajath, PK Sikha, AS Charan, M Padmavathamma, Y Kalyani, ...
    Journal of Pharmacy Research 5 (7), 3834-3836 , 2012
    2012
    Citations: 1
  • SIMULTANEOUS METHOD VALIDATION FOR THE ESTIMATION OF NIVOLUMAB AND CABOZANTINIB IN BULK AND PHARMACEUTICAL DOSAGE FORM BY RP-HPLC METHOD
    SC Archakam, K Palur, B Nagalakshmi, R Diviti
    World 5 (4) , 2026
    2026
  • Multivariate Ultraviolet Spectrophotometric Methods for the Simultaneous Analysis of Phenazone and Lidocaine in Ear Drops
    SC Archakam, K Palur, H Neelofar, SS Devarala
    Indian Journal of Pharmaceutical Sciences 86 (5), 1642-1651 , 2024
    2024
  • SIMULTANEOUS DETERMINATION OF CHLORPHENIRAMINE MALEATE AND PHENYLEPHRINE HYDROCHLORIDE IN LIQUID DOSAGE FORMS BY UV SPECTROSCOPIC METHODS
    N H, K Palur, SC Archakam, S Reddy C, M K, J Reddy K, H Priya K, ...
    African Journal of Biological Sciences 6 (8), 633-649 , 2024
    2024
  • Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in Commercial Formulation by Multitudinal UV and Multivariate FT-IR Spectroscopic Methods
    SC Archakam, K Palur, R Galla, SS Padiri, PK Tulasi, R Diviti
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH 58 (2), s552-s557 , 2024
    2024
  • Development and Validation of Chemometric Assisted UV Spectroscopic Methods for the Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in …
    RD K PALUR, SC ARCHAKAM, P PATAKAM, K ORUPALLI, P YADAVALI, Y POTHAPALA
    Asian Journal of Chemistry 35 (9), 2121-2124 , 2023
    2023
  • Development and Validation of a New Stability Indicating Reversed-phase High‑Performance Liquid Chromatography Method for the Simultaneous Estimation of Tegafur and Uracil in …
    SC Archakam
    Asian Journal of Pharmaceutics (AJP) 12 (03), 221-227 , 2018
    2018
  • New stability indicating RP-HPLC method for the simultaneous estimation of terbutaline sulphate and bromhexine hydrochloride in tablet dosage form
    CKB Sreenivasa Charan Archakam, Sridhar Chenchugari
    International Journal of Research in Pharmaceutical Sciences 9 (3), 776-781 , 2018
    2018