Chandragouda Raosaheb Patil

EDUCATION

M. Pharm, Ph.D.

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacology, Toxicology and Pharmaceutics, General Pharmacology, Toxicology and Pharmaceutics, Pharmaceutical Science, Drug Discovery

RECENT SCHOLAR PUBLICATIONS

Computational and invitro screening validates the repositioning potential of Coxibs as anti-fibrotic agents
S Karande, B Das, SS Acharya, A Kumar, H Patel, A Sharma, M Gupta, ...
Journal of Biomolecular Structure and Dynamics, 1-13 2024



Volatile Oil Containing Plants as Phytopharmaceuticals to Treat Psoriasis: A Review
PJ Vyas, SS Wagh, MG Kalaskar, KR Patil, AK Sharma, I Kazmi, ...
Current pharmaceutical biotechnology 25 (3), 313-339 2024



Oroxylin A: Nature's Arsenal Against Liver Fibrosis, Cancer, and Inflammatory Diseases
A Gera, L Yadav, CR Patil, MK Posa, B Chandrakanth, S Kumar
Health Sciences Review, 100143 2023



Active constituents of herbal medicines for breast cancer: Current status
S Kumar, M Mazhar, V Jogpal, S Yadav, RJ Jarag, S Bhatt, CR Patil
Journal of Applied Pharmaceutical Science 13 (8), 030-042 2023



Targeting inflammatory pathways for treatment of major depressive disorder
CR Patil, CS Gawli, S Bhatt
Drug Discovery Today, 103697 2023



Health Economic Burden of COVID-19 and its Comorbidities in India: An Exploratory Study
A Gupta, A Sharma, CR Patil, V Sharma, N Mittal, S Devi
Journal of Communicable Diseases (E-ISSN: 2581-351X & P-ISSN: 0019-5138) 55 2023



Emerging Novel Therapies for COVID-19: Implications for the Use of Nitric Oxide as an Anti-COVID-19 Therapy
RK Goyal, CR Patil, KR Patil
Nitric Oxide: From Research to Therapeutics, 259-278 2023



Potential role of biopeptides in the treatment of idiopathic pulmonary fibrosis
S Karande, K Sharma, A Kumar, S Charan, C Patil, A Sharma
Health Sciences Review 6, 100081 2023



Role of Oxidative Stress in Pathophysiological Progression of Schizophrenia
S Bhatt, T Upadhyay, CR Patil, KSR Pai, DK Chellappan, K Dua
Current Psychiatry Research and Reviews Formerly: Current Psychiatry Reviews 2023



Role of brain-gut-microbiota axis in depression: emerging therapeutic avenues
S Bhatt, J Kanoujia, S Mohana Lakshmi, CR Patil, G Gupta, ...
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS 2023



Acute Biochemical alterations during Phototherapy of Neonatal Icterus: Systematic Review and Meta-analysis
H Chaudhari, C Gawli, A Kumar, C Patil
2023



Next-generation sequencing in the biodiversity conservation of endangered medicinal plants
R Sharma, C Patil, J Majeed, S Kumar, G Aggarwal
Environmental Science and Pollution Research 29 (49), 73795-73808 2022



Development and biological evaluation of protective effect of kidney targeted N-acetylated chitosan nanoparticles containing thymoquinone for the treatment of DNA damage in
C Prajapati, YO Agrawal, VV Agnihotri, UB Mahajan, KR Patil, DD Patil, ...
International Journal of Biological Macromolecules 214, 391-401 2022



Identification of vaccine candidate against Omicron variant of SARS-CoV-2 using immunoinformatic approaches
Aasim, R Sharma, CR Patil, A Kumar, K Sharma
In Silico Pharmacology 10 (1), 12 2022



Theragnostic Strategies Harnessing the Self-Renewal Pathways of Stem-like Cells in the Acute Myeloid Leukemia
CNK Rahul Bhattacharjee 1, Sharad Ghosh, Arijit Nath, Asmita Basu, Ojaswi ...
Critical Reviews in Oncology and Hematology 2022



Thymoquinone produces cardioprotective effect in -receptor stimulated myocardial infarcted rats via subsiding oxidative stress and inflammation.
S Rathod, Y Agrawal, A Sherikar, KT Nakhate, CR Patil, MFN Meeran, ...
2022



Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation
S Rathod, Y Agrawal, A Sherikar, KT Nakhate, CR Patil, ...
Nutrients 14 (13), 2742 2022



Curcumin protects diabetic mice against isoproterenol-induced myocardial infarction by modulating CB2 cannabinoid receptors
HD Pawar, UB Mahajan, KT Nakhate, YO Agrawal, CR Patil, MFN Meeran, ...
Life 12 (5), 624 2022



Design and synthesis of the novel, selective WZ4002 analogue as EGFR-L858R/T790M tyrosine kinase inhibitors for targeted drug therapy in non-small-cell lung cancer (NSCLC)
R Pawara, I Ahmad, D Nayak, S Belamkar, S Surana, CN Kundu, C Patil, ...
Journal of Molecular Structure 1254, 132313 2022



Role of Brain–Gut–Microbiome Axis in Depression Comorbid with Asthma
S Bhatt, KSR Pai, CR Patil, SN Manjula, S Mohana Lakshmi
Microbiome in Inflammatory Lung Diseases, 135-151 2022

MOST CITED SCHOLAR PUBLICATIONS

Challenges and issues with streptozotocin-induced diabetes–a clinically relevant animal model to understand the diabetes pathogenesis and evaluate therapeutics
SN Goyal, NM Reddy, KR Patil, KT Nakhate, S Ojha, CR Patil, ...
Chemico-biological interactions 244, 49-63 2016
Citations: 372



Role of oxidative stress in depression
S Bhatt, AN Nagappa, CR Patil
Drug discovery today 25 (7), 1270-1276 2020
Citations: 371



Animal models of inflammation for screening of anti-inflammatory drugs: implications for the discovery and development of phytopharmaceuticals
KR Patil, UB Mahajan, BS Unger, SN Goyal, S Belemkar, SJ Surana, ...
International journal of molecular sciences 20 (18), 4367 2019
Citations: 277



Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin
SN Goyal, CP Prajapati, PR Gore, CR Patil, UB Mahajan, C Sharma, ...
Frontiers in pharmacology 8, 656 2017
Citations: 241



Protective effect of Kalanchoe pinnata pers.(Crassulaceae) on gentamicin-induced nephrotoxicity in rats
GV Harlalka, CR Patil, MR Patil
Indian journal of pharmacology 39 (4), 201-205 2007
Citations: 169



Pharmacological properties, molecular mechanisms, and pharmaceutical development of asiatic acid: a pentacyclic triterpenoid of therapeutic promise
MF Nagoor Meeran, SN Goyal, K Suchal, C Sharma, CR Patil, SK Ojha
Frontiers in pharmacology 9, 892 2018
Citations: 157



Anti-arthritic activity of bartogenic acid isolated from fruits of Barringtonia racemosa Roxb.(Lecythidaceae)
KR Patil, CR Patil, RB Jadhav, VK Mahajan, PR Patil, PS Gaikwad
Evidence-Based Complementary and Alternative Medicine 2011 2011
Citations: 148



Protective effects of cardamom in isoproterenol-induced myocardial infarction in rats
SN Goyal, C Sharma, UB Mahajan, CR Patil, YO Agrawal, S Kumari, ...
International journal of molecular sciences 16 (11), 27457-27469 2015
Citations: 129



Therapeutic potential of plants and plant derived phytochemicals against acetaminophen-induced liver injury
SB Subramanya, B Venkataraman, MFN Meeran, SN Goyal, CR Patil, ...
International journal of molecular sciences 19 (12), 3776 2018
Citations: 116



Role of reactive oxygen species in the progression of Alzheimer’s disease
CRP Shvetank Bhatt, Lakshman Puli
Drug Discovery Today 26 (Issue 3), Pages 79 2021
Citations: 101



Cardioprotective potentials of plant-derived small molecules against doxorubicin associated cardiotoxicity
S Ojha, H Al Taee, S Goyal, UB Mahajan, CR Patil, DS Arya, M Rajesh
Oxidative medicine and cellular longevity 2016 2016
Citations: 101



Protective effect of oleanolic acid on gentamicin induced nephrotoxicity in rats
CR Patil, RB Jadhav, PK Singh, S Mundada, PR Patil
Phytotherapy Research: An International Journal Devoted to Pharmacological 2010
Citations: 79



Anticonvulsant activity of aqueous root extract of Ficus religiosa
MS Patil, CR Patil, SW Patil, RB Jadhav
Journal of Ethnopharmacology 133 (1), 92-96 2011
Citations: 76



Protective effect of thymoquinone against cyclophosphamide-induced hemorrhagic cystitis through inhibiting DNA damage and upregulation of Nrf2 expression
PR Gore, CP Prajapati, UB Mahajan, SN Goyal, S Belemkar, S Ojha, ...
International Journal of Biological Sciences 12 (8), 944 2016
Citations: 72



Synthesis and anti-inflammatory activity of some new 4, 5-dihydro-1, 5-diaryl-1H-pyrazole-3-substituted-heteroazole derivatives
DV Dekhane, SS Pawar, S Gupta, MS Shingare, CR Patil, SN Thore
Bioorganic & medicinal chemistry letters 21 (21), 6527-6532 2011
Citations: 70



Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences
KR Patil, P Mohapatra, HM Patel, SN Goyal, S Ojha, CN Kundu, CR Patil
PloS one 10 (5), e0125709 2015
Citations: 64



The protective effect of apigenin on myocardial injury in diabetic rats mediating activation of the PPAR-γ pathway
UB Mahajan, G Chandrayan, CR Patil, DS Arya, K Suchal, YO Agrawal, ...
International Journal of Molecular Sciences 18 (4), 756 2017
Citations: 62



Synthesis, analgesic and anti-inflammatory activities of novel 3-(4-acetamido-benzyl)-5-substituted-1, 2, 4-oxadiazoles
M Farooqui, R Bora, CR Patil
European journal of medicinal chemistry 44 (2), 794-799 2009
Citations: 58



Anti-inflammatory activity of bartogenic acid containing fraction of fruits of Barringtonia racemosa Roxb. in acute and chronic animal models of inflammation
KR Patil, CR Patil
Journal of traditional and complementary medicine 7 (1), 86-93 2017
Citations: 56



In vivo and in vitro protective effects of omeprazole against neuropathic pain
4 Sanjay K. Chanchal,1,* Umesh B. Mahajan,1,* Sumit Siddharth,3,* Navyya ...
Scientific Reports 6 2016
Citations: 53