Evaluation of Growth Differentiation Factor 15 as an Early Biomarker of Anthracycline‐Induced Cardiotoxicity Using an Integrated PK/PD Model MS Dabour, AH Blaes, PA Jacobson, MN Kirstein, BN Zordoky, S Cheng Clinical and Translational Science 19 (5), e70595 , 2026 2026
Chronic Pharmacological Inhibition of p38 MAPK Induces Cardiac Hypertrophy in C57BL/6 Mice (Abstract ID: 228958) MR Daniel, M Dabour, IY Abdelgawad, MKO Grant, B Zordoky The Journal of Pharmacology and Experimental Therapeutics 393 (5) , 2026 2026
Differential Carfilzomib-induced Cardiotoxicity in AC16 and iPSC-Derived Cardiomyocytes and the Potential Protection by Canagliflozin (Abstract ID: 274027) M Dabour, NA Nguyen, B Ogle, B Zordoky The Journal of Pharmacology and Experimental Therapeutics 393 (5) , 2026 2026
Metformin Mitigates Doxorubicin-Induced Apoptosis and Senescence in THP-1 Immune Cells (Abstract ID: 273594) M Al-Hajri, M Dabour, MR Daniel, M Grant, B Zordoky The Journal of Pharmacology and Experimental Therapeutics 393 (5) , 2026 2026
Is endothelial dysfunction induced by aromatase inhibitors reversible after treatment M Dabour, A Shaaban, J Wolf, D Duprez, D Yee, B Zordoky, A Blaes Cancer Research 86 (7_Supplement), 5225-5225 , 2026 2026
MODEL-BASED EVALUATION OF GDF15 AS AN EARLY BIOMARKER OF ANTHRACYCLINE-INDUCED CARDIOTOXICITY USING AN INTEGRATED PK/PD MODEL M Dabour, A Blaes, P Jacobson, M Kirstein, B Zordoky, S Cheng CLINICAL PHARMACOLOGY & THERAPEUTICS 119 , 2026 2026
Integrated Omics Approach to Delineate the Mechanisms of Doxorubicin-Induced Cardiotoxicity MS Dabour, IY Abdelgawad, B Sadaf, MR Daniel, MKO Grant, AH Blaes, ... Pharmaceuticals 19 (2), 234 , 2026 2026 Citations: 2
Psychosocial stress exacerbates doxorubicin-induced cardiotoxicity in adult C57BL/6N mice MR Daniel, MKO Grant, M Razzoli, JE Abrahante, MS Dabour, ... 2026
Substrain-Dependent Differences in Doxorubicin-Induced Cardiotoxicity in Adult C57BL/6 Mice MR Daniel, MKO Grant, MS Dabour, M Razzoli, F Souza-Neto, ... Cardiovascular Toxicology 26 (1), 4 , 2026 2026 Citations: 3
Abstract Fri065: Transcriptomic Insights into Doxorubicin-induced Cardiotoxicity in C57BL/6 Sub-strains MR Daniel, M Grant, M Dabour, B Zordoky Circulation Research 137 (Suppl_1) , 2025 2025
Leveraging a Multi-Omics Approach to Reveal the Cardioprotective Effect of Losmapimod against Doxorubicin-Induced Cardiotoxicity in C57BL/6 Mice M Dabour, I Abdelgawad, B Sadaf, M Daniel, M Grant, B Zordoky Journal of Molecular and Cellular Cardiology Plus 12, 100445 , 2025 2025
Multi-omics approach to delineate the mechanisms of doxorubicin-induced cardiotoxicity MS Dabour, IY Abdelgawad, B Sadaf, MR Daniel, MK Grant, AH Blaes, ... Cancer Research 85 (8_Supplement_1), 787-787 , 2025 2025
Long-Term Care of Childhood Cancer Survivors at Risk for Cardiac Late Effects A Ackerman, D Ly, M Hall, MS Dabour, N Rodgers, S Narasimhan, ... Cardio Oncology 7 (3), 309-311 , 2025 2025 Citations: 1
Canagliflozin differentially modulates carfilzomib-induced endoplasmic reticulum stress in multiple myeloma and endothelial cells MS Dabour, MY George, MKO Grant, BN Zordoky Archives of Toxicology 99 (2), 729-744 , 2025 2025 Citations: 6
SGLT2 inhibitors in mitigating cancer therapy-related cardiac dysfunction: Expanding the evidence MS Dabour, AH Blaes, B Ramu, BN Zordoky Cardio Oncology 6 (6), 876-878 , 2024 2024 Citations: 6
Losmapimod ameliorates doxorubicin-induced cardiotoxicity through attenuating senescence and inflammatory pathways MS Dabour, IY Abdelgawad, B Sadaf, MR Daniel, MKO Grant, D Seelig, ... Biomedicine & Pharmacotherapy 179, 117288 , 2024 2024 Citations: 11
The Protective Effects of Empagliflozin in Carfilzomib-induced Cardiotoxicity in Mice: Unveiling the Crosstalk between Oxidative Stress, Inflammation, Endoplasmic Reticulum … MY George, M Dabour, E Rashad, B Zordoky Circulation research 135 , 2024 2024
Pharmacological Inhibition of p38 MAPK Attenuates Doxorubicin-induced Cardiotoxicity, Senescence, and Inflammation in C57BL/6 mice M Dabour, I Abdelgawad, B Sadaf, MR Daniel, M Grant, B Zordoky Circulation research 135 , 2024 2024
Abstract Mo004: The Protective Effects of Empagliflozin in Carfilzomib-induced Cardiotoxicity in Mice: Unveiling the Crosstalk between Oxidative Stress, Inflammation … MY George, M Dabour, E Rashad, B Zordoky Circulation Research 135 (Suppl_1), AMo004-AMo004 , 2024 2024
Abstract Mo002: Pharmacological Inhibition of p38 MAPK Attenuates Doxorubicin-induced Cardiotoxicity, Senescence, and Inflammation in C57BL/6 mice M Dabour, I Abdelgawad, bushra sadaf, MR DANIEL, M Grant, B Zordoky Circulation Research 135 (Suppl_1), AMo002-AMo002 , 2024 2024
MOST CITED SCHOLAR PUBLICATIONS
The Cardioprotective and Anticancer Effects of SGLT2 Inhibitors: JACC: CardioOncology State-of-the-Art Review MS Dabour, MY George, MR Daniel, AH Blaes, BN Zordoky Cardio Oncology 6 (2), 159-182 , 2024 2024 Citations: 130
Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence IY Abdelgawad, KT Sadak, DW Lone, MS Dabour, LJ Niedernhofer, ... Pharmacology & therapeutics 221, 107751 , 2021 2021 Citations: 55
Canagliflozin mitigates carfilzomib-induced endothelial apoptosis via an AMPK-dependent pathway MS Dabour, IY Abdelgawad, MKO Grant, ES El-Sawaf, BN Zordoky Biomedicine & Pharmacotherapy 164, 114907 , 2023 2023 Citations: 31
Empagliflozin alleviates carfilzomib-induced cardiotoxicity in mice by modulating oxidative stress, inflammatory response, endoplasmic reticulum stress, and autophagy MY George, MS Dabour, E Rashad, BN Zordoky Antioxidants 13 (6), 671 , 2024 2024 Citations: 23
Decreasing cardiac iron overload with Amlodipine and Spirulina in children with β-thalassemia SM El-Haggar, MR El-Shanshory, RA El-shafey, MS Dabour Pediatric hematology oncology journal 3 (3), 64-69 , 2018 2018 Citations: 12
Losmapimod ameliorates doxorubicin-induced cardiotoxicity through attenuating senescence and inflammatory pathways MS Dabour, IY Abdelgawad, B Sadaf, MR Daniel, MKO Grant, D Seelig, ... Biomedicine & Pharmacotherapy 179, 117288 , 2024 2024 Citations: 11
Canagliflozin differentially modulates carfilzomib-induced endoplasmic reticulum stress in multiple myeloma and endothelial cells MS Dabour, MY George, MKO Grant, BN Zordoky Archives of Toxicology 99 (2), 729-744 , 2025 2025 Citations: 6
SGLT2 inhibitors in mitigating cancer therapy-related cardiac dysfunction: Expanding the evidence MS Dabour, AH Blaes, B Ramu, BN Zordoky Cardio Oncology 6 (6), 876-878 , 2024 2024 Citations: 6
Substrain-Dependent Differences in Doxorubicin-Induced Cardiotoxicity in Adult C57BL/6 Mice MR Daniel, MKO Grant, MS Dabour, M Razzoli, F Souza-Neto, ... Cardiovascular Toxicology 26 (1), 4 , 2026 2026 Citations: 3
Integrated Omics Approach to Delineate the Mechanisms of Doxorubicin-Induced Cardiotoxicity MS Dabour, IY Abdelgawad, B Sadaf, MR Daniel, MKO Grant, AH Blaes, ... Pharmaceuticals 19 (2), 234 , 2026 2026 Citations: 2
Long-Term Care of Childhood Cancer Survivors at Risk for Cardiac Late Effects A Ackerman, D Ly, M Hall, MS Dabour, N Rodgers, S Narasimhan, ... Cardio Oncology 7 (3), 309-311 , 2025 2025 Citations: 1
Evaluation of Growth Differentiation Factor 15 as an Early Biomarker of Anthracycline‐Induced Cardiotoxicity Using an Integrated PK/PD Model MS Dabour, AH Blaes, PA Jacobson, MN Kirstein, BN Zordoky, S Cheng Clinical and Translational Science 19 (5), e70595 , 2026 2026
Chronic Pharmacological Inhibition of p38 MAPK Induces Cardiac Hypertrophy in C57BL/6 Mice (Abstract ID: 228958) MR Daniel, M Dabour, IY Abdelgawad, MKO Grant, B Zordoky The Journal of Pharmacology and Experimental Therapeutics 393 (5) , 2026 2026
Differential Carfilzomib-induced Cardiotoxicity in AC16 and iPSC-Derived Cardiomyocytes and the Potential Protection by Canagliflozin (Abstract ID: 274027) M Dabour, NA Nguyen, B Ogle, B Zordoky The Journal of Pharmacology and Experimental Therapeutics 393 (5) , 2026 2026
Metformin Mitigates Doxorubicin-Induced Apoptosis and Senescence in THP-1 Immune Cells (Abstract ID: 273594) M Al-Hajri, M Dabour, MR Daniel, M Grant, B Zordoky The Journal of Pharmacology and Experimental Therapeutics 393 (5) , 2026 2026
Is endothelial dysfunction induced by aromatase inhibitors reversible after treatment M Dabour, A Shaaban, J Wolf, D Duprez, D Yee, B Zordoky, A Blaes Cancer Research 86 (7_Supplement), 5225-5225 , 2026 2026
MODEL-BASED EVALUATION OF GDF15 AS AN EARLY BIOMARKER OF ANTHRACYCLINE-INDUCED CARDIOTOXICITY USING AN INTEGRATED PK/PD MODEL M Dabour, A Blaes, P Jacobson, M Kirstein, B Zordoky, S Cheng CLINICAL PHARMACOLOGY & THERAPEUTICS 119 , 2026 2026
Psychosocial stress exacerbates doxorubicin-induced cardiotoxicity in adult C57BL/6N mice MR Daniel, MKO Grant, M Razzoli, JE Abrahante, MS Dabour, ... 2026
Abstract Fri065: Transcriptomic Insights into Doxorubicin-induced Cardiotoxicity in C57BL/6 Sub-strains MR Daniel, M Grant, M Dabour, B Zordoky Circulation Research 137 (Suppl_1) , 2025 2025
Leveraging a Multi-Omics Approach to Reveal the Cardioprotective Effect of Losmapimod against Doxorubicin-Induced Cardiotoxicity in C57BL/6 Mice M Dabour, I Abdelgawad, B Sadaf, M Daniel, M Grant, B Zordoky Journal of Molecular and Cellular Cardiology Plus 12, 100445 , 2025 2025
