Dr. Delower Hossain, DVM, MSc, PhD (Fellow)
@sau.edu.bd
Assistant Professor, Department of Medicine & Public Health, Faculty of Animal Science & Veterinary Medicine, Sher-e-Bangla Agricultural University
DR. Delower Hossain, working as Assistant Professor, Dept. of Medicine and Public Health under Faculty of Animal Science and Veterinary Medicine at Sher-e-Bangla Agricultural University (SAU), Dhaka, Bangladesh since December 2018. He has completed his MS (Medicine) degree under Dept. of Medicine and Surgery at 2019 from Chattogram Veterinary and Animal Sciences University (CVASU). He has completed his Doctor of Veterinary Medicine (DVM) degree at 2016 from CVASU. He has been secured an excellent academic record with a one-year duration internship and externship program to complete DVM. He won the Best Clinical Award for excellent clinical performance at S.A. Quaderi Teaching Hospital, (CVASU) at 2015. He has immense interest to work for animal health and welfare. He had been working as Research Assistant (RA) in a Bangladesh-Sweden-Netherlands collaborative project “Development of Udder Health Control Programme in Dairy cows in Bangladesh” funded by Swedish Research Council, Sweden fr
RESEARCH, TEACHING, or OTHER INTERESTS
Veterinary, Infectious Diseases, Immunology and Microbiology, Public Health, Environmental and Occupational Health
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Shamsaldeen Ibrahim Saeed, Nor Fadhilah Kamaruzzaman, Noel Gahamanyi, Thi Thu Hoai Nguyen, Delower Hossain, and Ivan Kahwa
Springer Science and Business Media LLC
Shamsaldeen Ibrahim Saeed, Nor Fadhilah Kamaruzzaman, Noel Gahamanyi, Thi Thu Hoai Nguyen, Delower Hossain, and Ivan Kahwa
Springer Science and Business Media LLC
AbstractGlobally, Mastitis is a disease commonly affecting dairy cattle which leads to the use of antimicrobials. The majority of mastitis etiological agents are bacterial pathogens and Staphylococcus aureus is the predominant causative agent. Antimicrobial treatment is administered mainly via intramammary and intramuscular routes. Due to increasing antimicrobial resistance (AMR) often associated with antimicrobial misuse, the treatment of mastitis is becoming challenging with less alternative treatment options. Besides, biofilms formation and ability of mastitis-causing bacteria to enter and adhere within the cells of the mammary epithelium complicate the treatment of bovine mastitis. In this review article, we address the challenges in treating mastitis through conventional antibiotic treatment because of the rising AMR, biofilms formation, and the intracellular survival of bacteria. This review article describes different alternative treatments including phytochemical compounds, antimicrobial peptides (AMPs), phage therapy, and Graphene Nanomaterial-Based Therapy that can potentially be further developed to complement existing antimicrobial therapy and overcome the growing threat of AMR in etiologies of mastitis.
Nasir Uddin, Ariful Islam, Tania Akhter, Tasnim Ara, Delower Hossain, Craig Fullstone, Sam Enoch, and Alice C. Hughes
Cambridge University Press (CUP)
AbstractWildlife markets are hotspots for illegal wildlife trade, with traders operating as a result of weak monitoring and law enforcement. Knowledge of species traded, sources, and routes used for transport is needed to identify illegal wildlife trade markets and intervene to stem trade. We conducted surveys in 13 wildlife markets across Bangladesh every month during January-December 2019 to assess the abundance and diversity of wildlife taxa traded and the factors driving this trade. Passeriformes, Columbiformes, Psittaciformes, Artiodactyla, Carnivora and Testudines were the most traded orders. Wildlife markets were also centres of trade for high-value species, including the tiger Panthera tigris, crocodile Crocodylus porosus and tortoises. In hill markets and peri-urban markets the most commonly sold species originated from nearby forests, whereas urban markets included both native species and exotic species sourced internationally. Market type, road links to the market, the presence of law enforcement agencies, proximity to a port and form of sale (live animals or byproducts) all significantly influenced what is being traded. Trade of mammals, reptiles, high-value wildlife species and threatened species was less common in markets proximal to law enforcement agencies. Markets close to seaports or airports were more likely to sell mammals, threatened species and high-value wildlife. Based on our results, we recommend a set of interventions to help reduce market-based wildlife trade in Bangladesh.
Md. Farhan Hasan, Anas Bin Harun, Delower Hossain, Sabiha Zarin Tasnim Bristi, A. H. M. Musleh Uddin, and Md Robiul Karim
Springer Science and Business Media LLC
AHM Musleh Uddin, Tanjila Hasan, Delower Hossain, Kamrun Nahar, Tauhidul Islam, MD. Tanvir Islam, Md. Sawkat Hasan Saraf, Md Robiul Karim, Mohammad Atikuzzaman, and Md. Irtija Ahsan
Wiley
AbstractRaising awareness about Toxoplasma gondii infection among cat owners in Bangladesh is indispensable to formulate persuasive management tactics to avoid zoonotic infections from pet cats. However, to the authors' best knowledge, no studies have been performed in Bangladesh to determine knowledge and practices of toxoplasmosis in cat owners. Therefore, the objectives of the current study were to cover this research gap. We carried out a cross‐sectional study in Bangladesh from June 2020 through December 2021. A structured online questionnaire was distributed to cat owners, which were voluntarily completed by them. The questionnaire included socio‐demographic data, aetiology, transmissions, clinical signs, and preventive practices towards toxoplasmosis. Overall, 1,019 cat owners participated voluntarily in the cross‐sectional survey. Among them, 793 (77.82%) participants showed poor knowledge regarding toxoplasmosis. Under specific knowledge sections, 62.51% of the participants revealed incorrect knowledge that toxoplasmosis was a zoonotic disease. In the same way, (72.03–85.77) % of the cat owners were unaware that the disease could be transmitted from improperly washed vegetables, raw or undercooked meat and fish, and contaminated water and milk with cat faeces. Respondents' age, education, occupation, residence type, and marital status were significantly (p < .05) associated with their knowledge level. Besides, 94.11% of cat owners had a good practice level. They followed good practices in different issues; however, they practiced those activities without knowing their impacts on disease control. Cat owners' age, education, occupation, and residence type had a significant (p < .05) association with the practice level against toxoplasmosis. This is the first study highlighting the low level of knowledge among cat owners about toxoplasmosis in Bangladesh. These knowledge gaps could increase the risk and transmission of Toxoplasma gondii infection among them and their families. The survey recommends the arrangement of educational training and programmes to increase the awareness of toxoplasmosis among cat owners.
Md Saiful Bari, Md. Mizanur Rahman, Ylva Persson, Marjolein Derks, Md. Abu Sayeed, Delower Hossain, Shuvo Singha, Md. Ahasanul Hoque, Subramnian Sivaraman, Palika Fernando,et al.
Springer Science and Business Media LLC
Md Robiul Karim, Delower Hossain, AHM Musleh Uddin, and Farzana Islam Rume
Elsevier
Uddin A.H.M.M.
Malaysian Society of Parasitology and Tropical Medicine
Toxoplasma gondii is an obligate intracellular protozoon which causes toxoplasmosis, an important zoonotic disease that is endemic worldwide. Common sources of T. gondii infection in humans are food or water contaminated with oocysts and raw or undercooked meat with cysts. In animals, common sources of infection include feed, water, or litter contaminated with oocysts. The diagnosis and molecular characterization of T. gondii infection in humans and animals is crucial due to public and veterinary health importance. Various traditional and serological methods have been used in clinical practice for toxoplasmosis diagnosis, but interpreting the results remains a challenge. Several molecular techniques have also been used for the detection and genetic characterization of T. gondii , but primarily in research settings. In this paper, we review the techniques that are currently used for the diagnosis and genetic characterization of T. gondii in humans and animals, along with their advantages and disadvantages. The techniques reviewed have laid the groundwork for the future development of more effective and precise detection and characterization of T. gondii . These advances will contribute to a better understanding of epidemiology, prevention and control of toxoplasmosis. Thus, this review would be of particular interest to clinical physicians, veterinarians and researchers.
Tanjila Hasan, Abdul Mannan, Delower Hossain, Azizunnesa Rekha, Md. Monir Hossan, Mohammad Abdul Alim, and AHM Musleh Uddin
Veterinary World
Background and Aim: Toxoplasma gondii is a protozoan parasite that is responsible for the major cause of congenital diseases, abortion, and stillbirth in humans and farm animals. Primary infection in pregnant goats due to T. gondii leads to abortion and significant economic losses in the livestock industry. Moreover, very few studies have been performed for the identification of T. gondii from aborted fetuses of goats. The study was conducted for the molecular identification of Toxoplasma gondii from aborted fetuses of goats in Chattogram, Bangladesh. Materials and Methods: Twenty aborted fetuses of goats were collected from 52 farms in the study area. A nested polymerase chain reaction (PCR) assay targeting the B1 gene was performed, and a positive sample yield of 197 bp amplified DNA products consistent with T. gondii. Results: The overall prevalence of toxoplasmosis in the aborted fetus of goats was 35.0%. Heart muscle, liver, brain, and placenta showed positive PCR results. The risk factors related to the does age, presence of cats in farms, and aborted fetus age were found to be statistically significant (p<0.05). Our results showed that T. gondii is a major possible causal factor for abortion and reproductive failure in goats. The high prevalence of T. gondii infection in aborted fetuses of goats revealed that T. gondii could be imperative in causing reproductive failure in goats. Conclusion: Active or congenital toxoplasmosis was shown by the presence of T. gondii in fetal tissues, which is a matter of concern as this parasite has zoonotic significance and causes economic hazards to the livestock industry by causing various reproductive problems. Therefore, proper control measures and strategies are needed to reduce the rate of abortion in goats, ultimately saving the livestock industry.
Shuvo Singha, Gerrit Koop, Ylva Persson, Delower Hossain, Lauren Scanlon, Marjolein Derks, Md. Ahasanul Hoque, and Md. Mizanur Rahman
MDPI AG
Clinical mastitis (CM) is an important production disease in dairy cows, but much of the knowledge required to effectively control CM is lacking, specifically in low-income countries where most farms are small and have specific dairy management, such as regular udder cleaning and practicing hand milking. Therefore, we conducted a 6-month-long cohort study to (a) estimate the incidence rate of clinical mastitis (IRCM) at the cow and quarter level, (b) identify risk factors for the occurrence of CM, (c) describe the etiology of CM, and (d) quantify antimicrobial susceptibility (AMS) against commonly used antimicrobial agents in S. aureus and non-aureus Staphylococcus spp. (NAS) in dairy farms in the Chattogram region of Bangladesh. On 24 farms, all cows were monitored for CM during a 6-month period. Cases of CM were identified by trained farmers and milk samples were collected aseptically before administering any antimicrobial therapy. In total, 1383 lactating cows were enrolled, which totaled 446 cow-years at risk. During the study period, 196 new cases of CM occurred, resulting in an estimated crude IRCM of 43.9 cases per 100 cow-years, though this varied substantially between farms. Among the tested CM quarter samples, Streptococci (22.9%) followed by non-aureus staphylococci (20.3%) were the most frequently isolated pathogens and resistance of S. aureus and NAS against penicillin (2 out of 3 and 27 out of 39 isolates, respectively) and oxacillin (2 out of 3 and 38 out of 39 isolates, respectively) was common. The IRCM was associated with a high milk yield, 28 to 90 days in milk, and a higher body condition score. Our results show that there is substantial room for udder health improvement on most farms.
Ahmed H. Abed, Ahmed M. S. Menshawy, Mohamed M. A. Zeinhom, Delower Hossain, Eman Khalifa, Gamal Wareth, and Mohamed F. Awad
MDPI AG
Mastitis is a significant disease affecting dairy cattle farms in Egypt. The current study aimed to investigate the prevalence and major bacterial pathogens causing subclinical mastitis (SCM) in three bovine dairy herds, with a history of SCM, at three Governorates in North Upper Egypt. The antimicrobial resistance profiles and specific virulence-associated genes causing bovine SCM were investigated. One thousand sixty-quarter milk samples (QMS) were collected aseptically from 270 apparently healthy cows in three farms and examined. The total prevalence of SCM was 46% and 44.8% based on California Mastitis Test (CMT) and Somatic Cell Count (SCC), respectively. Bacteriological examination of CMT positive quarters revealed that the prevalence of bacterial isolation in subclinically mastitic quarters was 90.4% (26 and 64.3% had single and mixed isolates, respectively). The most frequent bacterial isolates were E. coli (49.8%), Staphylococcus aureus (44.9%), streptococci (44.1%) and non-aureus staphylococci (NAS) (37.1%). Antimicrobial susceptibility testing of isolates revealed a high degree of resistance to the most commonly used antimicrobial compound in human and veterinary medicine. Implementation of PCR revealed the presence of mecA and blaZ genes in 60% and 46.7% of S. aureus isolates and in 26.7% and 53.3% of NAS, respectively. Meanwhile 73.3% of streptococci isolates harbored aph(3’)-IIIa gene conferring resistance to aminoglycosides and cfb gene. All E. coli isolates harbored tetA gene conferring resistance to tetracycline and sul1 gene conferring resistance to sulfonamides. The fimH and tsh genes were found in 80% and 60%, respectively. A significant association between the phenotypes and genotypes of AMR in different bacteria was recorded. The presence of a high prevalence of SCM in dairy animals impacts milk production and milk quality. The coexistence of pathogenic bacteria in milk is alarming, threatens human health and has a public health significance. Herd health improvement interventions are required to protect human health and society.
Lorraine Chapot, Md Samun Sarker, Ruhena Begum, Delower Hossain, Rahima Akter, Md Mehedi Hasan, Zamila Bueaza Bupasha, Md Bayzid, Md Salauddin, Md Shafiullah Parvej,et al.
MDPI AG
The use of antibiotics in animals for both therapeutic and non-therapeutic purposes is a major driver of the emergence and spread of antimicrobial resistance (AMR). While several studies have investigated prescription and consumption patterns in humans, little attention has been paid to the veterinary sector. A cross-sectional study was conducted in 3002 veterinary students (VS) and non-medical students (NMS) from 12 universities in Bangladesh to explore their knowledge, attitudes and practices (KAP) about antibiotics and AMR using a self-administered questionnaire, and assess the influence of the veterinary curriculum. KAP regarding antibiotic use and AMR was significantly higher in veterinary than non-medical students, and in first-year than final-year students. However, gaps in knowledge and practices were highlighted, suggesting deficiencies in training. Moreover, final-year veterinary students were found to be more likely than first-year students to use antibiotics without instructions, which could indicate deficiencies in their curriculum. Although the study suggested a positive impact of the veterinary curriculum on KAP about antibiotics and AMR in Bangladesh, critical gaps remain that are likely to contribute to inadequate use in their future practice. Therefore, there is scope for improving educational programs on AMR in professional curricula.
Umme Kulsum, Delower Hossain, Azizul Hoque, Abdul Ahad, and Pankaj Chakraborty
ResearchersLinks Ltd
| Chlamydia ( C. ) psittaci is an important zoonotic pathogen that circulates in a wide range of avian species, mammals and humans . A cross-sectional study was conducted based on the seroprevalence of C. psittaci in association to the potential risk factors with Chlamydia infection in pigeons to assess their role as source of human Chlamydia infection. A total of 91 samples were screened by Enzyme linked immunosorbent assay (Sandwich-ELISA) to detect C. psittaci antibody (Cps-Ab). The results indicated that, 6 (6.6%) samples contained C. psittaci antibody (Cps-Ab) and the duration of illness and clinical conditions in pigeons had significant influence (p< 0.05) on Chlamydia seropositivity. In addition, the prevalence of C. psittaci antibody was predominant in local pigeons and most of the seropositive pigeons were less than 6 months of age. Based on the presence of antibody against C. psittaci the study suggests that, Chlamydia is prevalent among pigeons in the study area. Therefore, the pigeon may be a potential source of human Chlamydia infection in Bangladesh. Moreover, careful initiative is needed to protect it involving community, government and animal protection societies as well as scientists.
Sazeda Akter, Md. Mizanur Rahman, Md. Abu Sayeed, Md. Nurul Islam, Delower Hossain, Md. Ahasanul Hoque, and Gerrit Koop
Elsevier BV