8-Oxo-2′-Deoxyguanosine: Oxidative Stress Control N. V. Marmiy, D. S. Esipov Russian Journal of Bioorganic Chemistry, 2025 8-Oxo-2′-deoxyguanosine is a well-known marker of oxidative stress. Research over the past decade suggests that this compound is probably not a byproduct of oxidative DNA damage, but an important bioregulator driving the cellular response to stress. This review collected and analyzed data on the participation of 8-oxo-2′-deoxyguanosine in the processes of mutagenesis, DNA repair, and regulation of gene expression, inflammatory responses, adaptive stress response, apoptosis, and cellular transformation. Particular attention is paid to the potential of 8-oxo-2′-deoxyguanosine as a therapeutic agent for the treatment of inflammatory, autoimmune, degenerative, and oncological diseases, as well as of traumatic and toxic injuries.
Pseudo-minimal surfaces of revolution Mikhail S. Bukhtyak, Dmitrii E. Yesipov, and Vestnik Tomskogo Gosudarstvennogo Universiteta Matematika I Mekhanika, 2022 This paper is a follow-up to the first author’s series of works about shape modeling of orthotropic elastic material that takes the equilibrium form inside the area with the specified boundaries. M.S. Bukhtyak, in a number of his publications of 20162020, proposed an approach to the model building based on the application of surfaces with a constant ratio of principal curvatures. These surfaces are named pseudo-minimal surfaces. The theorem of existence has been demonstrated and the finitely-element model has been built. The condition distinguishing the class of pseudo-minimal surfaces, as applied to ruled surfaces, is either satisfied identically (trivial subclasses) or is satisfied along a family of lines. The corresponding classes of ruled surfaces have been comprehensively characterized geometrically. A partial differential equation that defines (in the local sense) the class of pseudo-minimal surfaces is very complex for analysis, which makes it relevant to consider approximate solutions. The current paper considers the pseudo-minimal surfaces of revolution. Generation of the approximate solutions is complicated by the tendency of the formal Taylor polynomial to diverge. However, the approximate solutions (of course, not ideal) have been generated. Contribution of the authors: the authors contributed equally to this article. The authors declare no conflicts of interests.
Potential geroprotector properties of the extract of reindeer antler powder in experiments on cultured cells Advances in Gerontology Uspekhi Gerontologii Rossiskai X0361 A Akademii X0361 A Nauk Gerontologicheskoe Obshchestvo, 2008
8-oxo-2'-deoxyguanosine accumulation in DNA from "stationary phase aging" cultured cells Advances in Gerontology Uspekhi Gerontologii Rossiskai X0361 A Akademii X0361 A Nauk Gerontologicheskoe Obshchestvo, 2008
Determination of oligonucleotide molecular masses by MALDI mass spectrometry Bioorganicheskaya Khimiya, 2005
The synthesis of phosphoceramide azidothymidine and phosphoceramide didehydrodeoxythymidine Russian Journal of Bioorganic Chemistry, 1997
The Synthesis of Phosphoceramide Azidothymidine and Phosphoceramide Didehydrodeoxythymidine Bioorganicheskaya Khimiya, 1997
Preparation of Ceramide Phosphothymidine, a Model Compound for the Sphingophosphooligonucleotide Synthesis Bioorganicheskaya Khimiya, 1996
Mutants of Human Tumor Necrosis Factor: Preparation and Properties Bioorganicheskaya Khimiya, 1996
Preparation of ceramide phosphothymidine, a model compound for the sphingophosphooligonucleotide synthesis Russian Journal of Bioorganic Chemistry, 1996
Mutants of human tumor necrosis factor: Preparation and properties Russian Journal of Bioorganic Chemistry, 1996
Human tumor necrosis factor mutants: preparation and some properties Bioorganicheskaia Khimiia, 1996
Study of resistance of the human immunodeficiency virus to azidothymidine. II. Kinetic characteristics of 'AZT-resistant' mutant forms of reverse transcriptase Biokhimiya, 1996
Study on the resistance of human immunodeficiency virus to azidothymidine. II. Kinetic characteristics of "AZT-resistant mutants" of reverse transcriptase Biochemistry Moscow, 1996
Selectively cleaved synthetic oligodeoxyribonucleotides for reverse immobilization of DNA Bioorganicheskaia Khimiia, 1994
Studies of the resistance of the human immunodeficiency virus to azidothymidine. I. Kinetic studies of the interaction between reverse transcriptase and a series of its mutant forms with substrates and azidothymidine-5'-trisphosphate Biokhimiya, 1994
Hybrid human lymphokine genes. I.Design of recombinant plasmids coding hybrids of immune interferon and human tumor necrosis factor Bioorganicheskaia Khimiia, 1991
Enzymatic ligation of DNA fragments containing phosphoamide modification of the internucleotide bonds Bioorganicheskaia Khimiia, 1991
Construction and properties of fusion proteins between human interferon-gamma and human tumour necrosis factors alpha and beta. Biomedical Science, 1991
Solid phase ligation of synthetic DNA fragments Bioorganicheskaia Khimiia, 1990
Synthesis of 5'-phosphorylated oligodeoxyribonucleotides by the H-phosphonate method Bioorganicheskaia Khimiia, 1989
