Dr Ashwini Kumar

@manipal.edu

Associate Professor, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Manipal
Manipal Academy of Higher Education, Manipal

Dr Ashwini Kumar


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https://researchid.co/drashwinikumar

RESEARCH, TEACHING, or OTHER INTERESTS

Pathology and Forensic Medicine, Biochemistry (medical), Cardiology and Cardiovascular Medicine, Anatomy
19

Scopus Publications

Scopus Publications

  • Decellularization techniques: unveiling the blueprint for tracheal tissue engineering
    Keisha T. Gomes, Palla Ranga Prasad, Jagnoor Singh Sandhu, Ashwini Kumar, Naveena A. N. Kumar, N. B. Shridhar, Bharti Bisht, Manash K. Paul
    Frontiers in Bioengineering and Biotechnology, 2025
    Certain congenital or acquired diseases and defects such as tracheo-oesophageal fistula, tracheomalacia, tracheal stenosis, airway ischemia, infections, and tumours can cause damage to the trachea. Treatments available do not offer any permanent solutions. Moreover, long-segment defects in the trachea have no available surgical treatments. Tissue engineering has gained popularity in current regenerative medicine as a promising approach to bridge this gap. Among the various tissue engineering techniques, decellularization is a widely used approach that removes the cellular and nuclear contents from the tissue while preserving the native extracellular matrix components. The decellularized scaffolds exhibit significantly lower immunogenicity and retain the essential biomechanical and proangiogenic properties of native tissue, creating a foundation for trachea regeneration. The present review provides an overview of trachea decellularization advancements, exploring how recellularization approaches can be optimized by using various stem cells and tissue-specific cells to restore the scaffold’s structure and function. We examine critical factors such as mechanical properties, revascularization, and immunogenicity involved in the transplantation of tissue-engineered grafts.
  • Ballistic armor—a study on the impact of air gun pellets on jean cloth
    B. G. Chinmayi, Ashwini Kumar, M. S. Arjun
    Egyptian Journal of Forensic Sciences, 2023
    Background Ballistics deals with the study of projectile propulsion, flight, and impact in any medium. Different garment materials can have varying effects when it comes to the penetration of pellets into the body. Body armor has been around for a long time. Dhal, a curving strip of rhino hide, was possibly the first armor in India, used for sword fighting or defense against arrows and spears. It gave way to steel armor, which protected the body’s essential organs from spear and arrow strikes. The current study is primarily concerned with how jeans material, when employed as body armor, contributes to the inquiry. The present study also examines how airgun pellets fired at various ranges affect jeans clothing wrapped around gel blocks. Results The study concluded that when fired at varied ranges, there was no significant variation in the diameters of the entry holes on clothing material. The gel block covered with jeans clothing was not found to be more damaged. Conclusions The findings also indicate that pellets had larger track lengths regardless of the range from which they were fired.
  • SEX DETERMINATION FROM FINGERPRINTS AMONG SOUTH INDIAN POPULATION
    Remya Renjith, Ashwini Kumar
    Journal of Forensic Medicine and Toxicology, 2021
  • Rupture of berry aneurysm – a preventable fatality
    Ashwini Kumar, Swetha Sritharan, Ajay Hedge, Vikram Palimar, Sowmya Shashidhara
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2020
    Berry aneurysm is one of the commonest cause of subarachnoid haemorrhage commonly seen in bifurcation sites of circle of Willis. Unruptured aneurysms are asymptomatic and are usually missed unless suspected, even with radiological methods. Common risk factors include Autosomal Dominant Polycystic Kidney Disease (AD-PKD), smoking, hypertension, connective tissue disorders etc.
  • Amniotic fluid embolism-A rare case report
    Ashwini Kumar, Vrinda Chopra, M Nayak Deepak, Shankar M Bakkannavar, Sowmya Shashidhara
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2020
    Amniotic fluid embolism (AFE) is one of the most catastrophic complications of pregnancy in which it is postulated that amniotic fluid, fetal cells, hair, or other debris enters the maternal pulmonary circulation, causing cardiovascular collapse and other complications which are a cause of high case fatality. It was first reported by Meyer in 1926. The incidence of Amniotic fluid embolism is rare, and the exact pathophysiology is still unknown. The process is similar to anaphylaxis than to embolism, so also termed as anaphylactoid syndrome of pregnancy because foetal tissue or amniotic fluid components are not universally found in women who present with signs and symptoms attributable to AFE.
  • Analysis of fatal road traffic accidents in a township of south India
    Ashwini Kumar, Baishwanar Banerjee, M S Arjun, Anitta Joseph, Vinod C Nayak, Sowmya Shashidhara
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2020
    Road traffic accidents have been one of the most significant public health issue due to its frequency of occurrence and increasing vehicle density, worldwide. With the aim of considering the socio segment profile of road traffic casualties, the forerunner factors influencing road traffic accidents and to decide the different components influencing demise rate following road traffic accidents, this retrospective study of medico -legal autopsies was conducted during October 2014 and October 2016 at the Department of Forensic Medicine&Toxicology, Kasturba Medical College Udupi District, Karnataka, South India. For the purpose of this study, autopsy files and inquest documents provided by the investigating officer were studied in detail and the data collected was analyzed using the statistical software SPSS version 11.0. Among the victims, 62.9% were males and 37.1% were females with male: female ratio of 2:1. The mean age of the casualties were 43.73 years and age bunch between 21 to 60 years were considered as casualties for the significant portion of road traffic fatalities. 31.13 % of the victims were pedestrians and 68.87% were vehicular occupants. 64.57 % of the victims travelled in the vehicle without using any safety measures. It was observed that tertiary health care (68.54%) had major effect on death rate followed by secondary (29.14%) and then primary health care (2.32%). Head injury alone was liable for nearly three-fourth of road traffic loss of life followed by abdominal injuries (29.8%) and wounds to the limbs (0.33%). The above findings show that road traffic accidents are a public health concern and there is a need to address this with health education, betterment ofthe roads, stricter enforcement ofthe traffic laws and expanding the system responding to health care emergencies.
  • Death due to fungal endocarditis – a case report
    Ashwini Kumar, Saumya Saxena, M Nayak Deepak, Anitha Shivajirao, Sowmya Shashidhara
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2020
    Sudden deaths of cardiac origin are usually caused by unexpected loss of heart function. One of the causes may be Infective endocarditis (IE) which refers to the microbial infection of the heart valves or mural endocardium that leads to the formation of thrombotic vegetations that cause calcification and destruction of underlying cardiac tissue. The vegetations are typically friable and embolize easily causing abscesses (Ring abscess), septic infarcts and mycotic aneurysms. Left untreated, IE may lead to congestive heart failure (CHF). Hence, it is important to discuss cases where IE was the main cause for death.
  • Fatal concealed wound-a rare case report
    Anshika Saini, Kulbir Singh Saini, Vinod C. Nayak, Ashwini Kumar, Nirmal Krishnan
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2020
    Stab wound is a common occurrence in homicidal cases when a sharp weapon is used. Fatality in such cases depends on identifying associated injuries and preventing complications. Sometimes the depth of these wounds can be misconstrued because of the formation ofperitoneal fat plug, tightly sealing the wound margin.
  • Acute mesenteric ischemia due to amphetamine use-a case report
    Anitha Shivaji, Ashwini Kumar, Vinod C Nayak, Vikram Palimar, Shankar M Bakkannavar, Nirmal Krishnan, Arpita Pradhan
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2020
    Introduction: Mesenteric ischemia is the cause leading to gangrene of the small intestine. The cause being atherosclerosis and is commonly seen in old individuals. However, in young patients, it is a rare phenomenon and the cause can be attributed to drugs of abuse such as cocaine, methamphetamine which makes our case distinct.
  • Amitraz: A Perpetual Silent Menace among Children in Developing Countries - A Case Report
    Sowmya Shashidhara, Suneel C. Mundkur, Shrikiran A. Hebbar, Ashwini Kumar, Vaisakh Sambasivan
    Pediatric Emergency Care, 2019
    Amitraz is an acaricide and insecticide used to treat ticks, which infest domestic animals in developing countries. Because of its widespread use, it is one of the common poisons unintentionally consumed by infants and children when left unsupervised. A 3-year-old boy was brought with unintentional consumption of Amitraz. On examination, he was found to be progressively drowsy, with an irregular pulse, bradycardia, and hypotension. He was treated with atropine, intravenous fluids, and dopamine infusion; hemodynamic stability was achieved within 36 hours after ingestion. Amitraz is an unusual but deadly poison unintentionally consumed by children. It can be suspected in the setting of rural households in developing countries having pets. There is no antidote available, and treatment is mainly supportive.
  • Estimation of the most significant foot measurement in determining the stature of an individual in Karnataka population
    M Nirmal Krishnan, Vinod C Nayak, Ashwini Kumar, Vikram Palimar, Shankar M Bakkannavar, S. Anitha, Chandni Gupta
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2019
  • Finger print patterns and gynecological cancer: An empirical study
    Bijoyini Bose, Vinod C Nayak, Vikram Palimar, Shankar M Bakkannavar, Anita Shivaji, Ashwini Kumar, Nirmal Krishnan
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2019
  • Determination of sex from human adult sternum
    Sajan Babu, Vikram Palimar, Anitha Sivaji Rao, Chandni Gupta, Vinod C Nayak, Ashwini Kumar, Shankar M Bakkannavar, M Nirmal Krishnan
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2019
  • Morphometry of organization of middle meningeal artery through the analysis of bony canal in human's skull: A clinico-anatomical and embryological insight
    ThittamaranahalliMuguregowda Honnegowda, Vineeth Dineshan, Ashwini Kumar
    Journal of Craniovertebral Junction and Spine, 2019
  • Forensic clinical photography: A game changer in medicolegal investigation and forensic science
    Renjulal Yesodharan, Vishnu Renjith, Ashwini Kumar, Vinod C Nayak
    Indian Journal of Forensic Medicine and Toxicology, 2018
  • Jellyfish envenomation: A chilling toxidrome of seizures and cyanosis – A case report
    Suneel Mundkur, Sowmya Shashidhara, Shrikiran Hebbar, Ashwini Kumar, Shravan Kanaparthi
    Sajch South African Journal of Child Health, 2018
  • A case of acute aluminum phosphide poisoning leading to demyelinating optic neuropathy
    Kumar Ashwini, Shashidhara Sowmya, Bhaskarananda Nalini, Kini Sandesh
    Toxicology International, 2016
  • A rare case of neem oil ingestion as a suicidal modality
    Research Journal of Pharmaceutical Biological and Chemical Sciences, 2016
  • Epidemiology of pedestrian fatalities in manipal: A retrospective study
    Journal of Punjab Academy of Forensic Medicine and Toxicology, 2015