Nitin Gupta

@mmimsr.mmumullana.org

Associate Professor, Department of General Medicine
Maharishi Markandeshwar Institute of Medical Sciences & Research - [MMIMSR], Mullana,Ambala.Haryana(India)



              

https://researchid.co/drnitin

EDUCATION

M.B.B.S, M.D(General Medicine)

RESEARCH INTERESTS

Neurology, Infectious disease, Drug resistance

133

Scopus Publications

78

Scholar Citations

5

Scholar h-index

2

Scholar i10-index

Scopus Publications


  • National Education Policy: A Holistic Development on the Horizon
    Nitin Gupta, Preethy Kathiresan, and Jitender Aneja
    SAGE Publications

  • The Comparative Accuracy of BISAP and PANC3 Scoring System for the Disease Severity and Outcome in Acute Pancreatitis in Tertiary Care Hospital from North India



  • Editorial: Fostering Tomorrow for the Future
    Henal Shah and Nitin Gupta
    SAGE Publications


  • Interventions for helping people recognise early signs of recurrence in bipolar disorder
    Sumeet Gupta, Ogba Onwuchekwa, Lakshmi Ramana Alla, Richard K Morriss, Rachel Steele, and Nitin Gupta
    Wiley


  • Learning Disability Certification in India: Quo Vadis
    Nitin Gupta, Nishant Goyal, and Eesha Sharma
    SAGE Publications
    Learning disorder (LD), one of the most common neurodevelopmental disorders, affects 3% to 10% of children. It is characterized by poor academic skills that are quantifiably below those expected for an individual’s chronological age (at least 1.5 standard deviation below the age-wise population mean). Significant interference with academic and/or occupational performance or with activities of daily living is observed. LD is confirmed with standardized achievement measures and comprehensive clinical assessments. Learning difficulties are usually noticed during school years; however, they may not manifest till later, whenever demands in academics exceed an individual’s capacity.

  • Challenging times, changing focus, and social psychiatry
    RSrinivasa Murthy and Nitin Gupta
    Medknow

  • Psychological impact of lung cancer: A cross-sectional study
    Kashish Dutta, Varinder Saini, Nitin Gupta, and Kranti Garg
    Medknow

  • Non-suicidal Self Injury: An Entity in Need of Validation?
    Nitin Gupta, Nidhi Chauhan, and Prerna Sharma
    SAGE Publications
    The motivation to avoid pain and injury is a fundamental instinct, crucial to the survival of human beings and other living species. However, for the last 1 to 2 decades, there is an increasing number of individuals presenting to clinicians with self-injurious behavior but “without an intent to die.” This phenomenon of harming oneself without the intent to die is referred to as Non-suicidal Self Injury (NSSI). NSSI is defined as “the direct and deliberate destruction of one’s own bodily tissue in the absence of lethal intent and for reasons not socially sanctioned.”1 Accidental and indirect self-injurious behaviors such as disordered eating, drug abuse, suicidal behaviors, and socially accepted behaviors (tattooing, piercing, or religious rituals) do not form part of NSSI. The recognition of this behavior led researchers to include NSSI in section III of DSM 5 as a “condition in need of further study.” ICD-10 included NSSI either as a symptom of borderline personality disorder or as “intentional selfinjury with a sharp object (X78),” whereas, ICD-11 does not include it as a diagnostic entity. While some researchers criticize the defined dichotomy between NSSI and suicidal behaviors, others are of the view that NSSI and suicide should be understood as lying on a continuum of self-harming behaviors.

  • Naturalistic study of 'Adherence to Follow-Up' in the initial 1 st year cohort of patients utilizing a tertiary hospital-based geriatric mental health-care service using the 'Service Evaluation Framework'
    Subhash Das, Nitin Gupta, and Tanupreet Kaur
    Medknow
    Background: There are very few specialised hospital with quality assurance services catering to the needs of the elderly with mental illness. The concept of 'Appointment adherence' has received little attention in the field of geriatric mental health from India. There is a need to study the pattern of 'drop-out' amongst geriatric patients. Method: An initial cohort of first 105 cases presenting to the clinic were followed up to explore their socio-demographic and clinical variables, overall functioning and satisfaction with the services. Adopting a 'naturalistic approach,' and using the 'service evaluation framework', at the assessment period of about 36 months, tools like socio-clinical profile, Hindi Mental State Examination (HMSE), Everyday Abilities Scale for India (EASI), Global Assessment of Function (GAF) scale, WHOQOL-BREF-Hindi version, Patient Satisfaction Scale (PAT-SAT) and 'Service Evaluation (SSS-16 and SSS-10 Practitioner Versions)' were administered. Result: 68 cases were available for assessment of functional outcome and satisfaction parameters were assessed for 78 of the cases. 75% had functional disorders and medical morbidity was present in more than 50% of cases. The mean score for WHOQOL-BREF and GAF were 44.4 (poor quality of life) and 72.91 (slight impairment in socio-occupational functioning) respectively. PAT-SAT score in all the sub-categories were above average. 'Organic' diagnosis patients had lower QoL on certain domains compared to 'functional' patients. Only 30.47% patients were coming for follow-up with 25.71% having died. Of the 32/68 (34.29%) cases who had dropped out, 50% were adherent to treatment in different ways. Additionally, GAF scores were lower in 'drop-out' group. Conclusions: There is a relatively high rate of 'drop-out' over a 3-year period. However, if patients keep coming for follow-up (i.e. do not 'drop-out'), they are more likely to show improvement in their level of social and occupational functioning.

  • “Persons with Disabilities”: Are We Doing Enough as a Society?
    Nitin Gupta, Jitender Aneja, and Preethy Kathiresan
    SAGE Publications


  • Comparison of effect of etomidate with propofol on hemodynamics during modified electroconvulsive therapy
    Richa Saroa, Divya Mehta, Sanjeev Palta, and Nitin Gupta
    Medknow
    Background and Aims: Studies comparing the effect of propofol and etomidate on hemodynamic parameters during electroconvulsive therapy (ECT) have shown ambiguous results. Although some studies observed a larger increase in blood pressure and heart rate during the use of etomidate than propofol in ECT, whereas some studies have shown no difference in hemodynamic parameters with the use of etomidate or propofol. Most of the studies done to compare the hemodynamic effects of etomidate and propofol were limited by small sample size or retrospective in nature. Therefore, we conducted a prospective randomized trial to compare the effects of etomidate and propofol on hemodynamics during ECT. Material and Methods: A prospective randomized crossover study was conducted on 30 patients with American Society of Anesthesiologist physical status I and II, between age 18 and 65 years, suffering from a mental disorder as per International Classification of Diseases-10 and requiring bilateral ECT as per clinical decision of consultant psychiatrist. They were randomized to receive both the drugs for their successive ECT sessions and were subjected to evaluation after clubbing together the ECT sessions of propofol or etomidate as anesthetic agent. Results: Duration of motor seizures was significantly more in patients receiving etomidate, whereas patients receiving propofol had more stable hemodynamics. Conclusion: Though propofol maintains stable hemodynamics during MECT, yet clinical applicability of etomidate outstrips it by a reasonable margin due to its better effect on seizure parameters.

  • Detection of inducible resistance to clindamycin among methicillin resistant and sensitive strains of Staphylococcus aureus from India
    Rosy Bala, Narinder Kaur, Nitin Gupta, Jyoti Chauhan, Ritu Garg, Harit Kumar, and Adesh K Saini
    Journal of Pure and Applied Microbiology
    The resistance to MLSB antibiotics, i.e. Macrolide-Lincosamide-Streptogramin B (MLSB), is an increasing problem among Methicillin-resistant Staphylococci. The resistance to macrolides can be by efflux mechanism or via inducible or constitutive resistance. Unfortunately, routine clindamycin susceptibility testing fails to detect the inducible resistance, which commonly results in treatment failure and necessitates incorporating a simple D-test to detect such resistance. A retrospective observational study was performed on S. aureus isolates from patients. The strains were subjected to antibiotic susceptibility testing followed by detection of mecA gene by a polymerase chain reaction and, the ‘D-test’ was performed to know the inducible resistance to clindamycin. A total of 235 isolates were identified as S. aureus. Antibiotic susceptibility test indicated 190 MRSA and 45 are sensitive to MLSB (MS). Inducible clindamycin resistance was found among 48 (20.4%) isolates and constitutive resistance in 104 (44.2%). MRSA strains had higher inducible and constitutive resistance than MSSA strains (22.1%, 51.6% and 13.3%, 13.3%, respectively). Clindamycin is a commonly used antibiotic in patients with MRSA infections to spare higher-end anti-MRSA antibiotics like linezolid and vancomycin. To detect inducible clindamycin to avoid treatment failures; the study showed the importance of incorporating the D-test in routine testing.

  • Leadership for mental health
    RSrinivasa Murthy and Nitin Gupta
    Medknow

  • Home-based care in the community
    Shikha Tyagi, Akshit Katoch, Subhash Das, and Nitin Gupta
    Medknow
    Treatment gap in mental health is vast and continues to remain a grim reality. Amongst community mental health care, one approach available is home based care (HBC). However, HBC services are almost lacking in India. Nevertheless, the limited evidence points towards a successful utility of HBC till date. In this article, the Chandigarh experience of HBC is presented and discussed in detail in order to demonstrate its utility and effectiveness. Lastly, recommendations are provided for the future of HBC.

  • Kocuria rosea bacteremia in chronic kidney disease patient: A rare case report
    Rosy Bala, Narinder Kaur, Nitin Gupta, and Udit Narang
    Journal of Pure and Applied Microbiology
    Kocuria sp. may cause bacteremia, peritonitis, brain abscesses, meningitis, endocarditis, and acute cholecystitis in immunocompromised individuals. Recent reports identified Kocuria rosea in bacteremia associated with in dwelling intravenous lines, continuous dialysis fluids etc. We report on the case of bacteremia caused by K.rosea, a gram-positive microorganism in a 65-year-old female with a known case of end-stage renal disease on hemodialysis. After Piperacillin and Tazobactam antibiotic treatment, the patient got cured of fever and infection. This report presents a rare case of K.rosea bacteremia successfully treated with common antibiotics. Proper identification systems should be there to know the cause of bacteremia. The bacteremia cases with rare organisms should not be ignored.

  • From the editor's desk
    Nitin Gupta
    Medknow

  • COVID-19 and manifest psychological morbidity: A case series
    Nitin Gupta, Parmod Kumar, Shubham Kamal, and Shubhangi Tuli
    Medknow
    The COVID-19 pandemic in India has been reported to be associated with numerous major mental health issues globally; the most common is – stress, anxiety, depressive symptoms, insomnia, denial, anger, and fear. This case series presents three different cases, wherein the COVID-19 pandemic resulted not only in deterioration of previous symptoms experienced by patients (obsessive–compulsive disorder and depression) but also led to the development of new symptoms specifically related to coronavirus (Psychosis). Authors highlight the need to develop preventive strategies for vulnerable groups and try to understand the etiopathogenesis of illnesses so developing, in order to identify support systems and management strategies during the pandemicrelated crisis.

  • Exposure to smartphone and screen media in children and adolescents and COVID-19 pandemic


  • Impact of lockdown on self-care management among patients with type 2 Diabetes Mellitus residing in Lucknow city, India – A cross-sectional study
    Ajoy Tiwari, Dinesh Kumar, Mohammad S. Ansari, Santosh Kumar Chaubey, Nitin R. Gupta, Vivek Agarwal, Kumar Prafull Chandra, Arunkumar r Pande, Rajiv Awasthi, Mukulesh Gupta,et al.
    Elsevier BV

  • Pain threshold and pain tolerance as a predictor of deliberate self-harm among adolescents and young adults
    Nitin Gupta, Mitthat Miglani, and BirSingh Chavan
    Medknow
    Background: Recently, the assessment of pain has been used as a parameter to differentiate adolescents who indulge in deliberate self-harm from healthy individuals. Aims and objectives: The present study was conducted to compare pain sensitivity between three groups, i.e., nonsuicidal self-injury/nonsuicidal self-harm (NSSI), suicide attempters (SA), and matched healthy control (NSSI, SA, and healthy controls). Materials and Methods: Ninety participants (30-NSSI, 30-SA, and 30 matched control) between the age of 10 and 25 years were inducted from the individuals who came for help at the outdoor and emergency services for recent self-harm. Pain sensitivity was assessed by cold pain stimulation test through a cold pressor task. Results: Pain threshold, pain tolerance, total pain index as well as pain experience intensity were significantly different in the three groups. Conclusion: Participants who indulge in NSSI and SA have significantly higher pain threshold, pain tolerance, total pain index, and pain experience intensity as compared to healthy control. Although all the pain parameters were higher in the NSSI group as compared to SA group, the difference did not reach to significant level.

RECENT SCHOLAR PUBLICATIONS

  • Red cell distribution width as a marker of disease severity and in-hospital mortality in patients with st-segment elevation myocardial infarction
    R Raval, S Gupta, N Gupta, MA Bashar
    Indian Journal of Critical Care Medicine: Peer-reviewed, Official 2024

  • Enhanced in-vitro anti-Candida efficacy of Euphorbia milii Des Moul mediated copper nanoparticles against clinically isolated Candida albicans
    R Bala, N Kaur, N Gupta, S Aman, S Shriwastav
    Current Medical Mycology 9 (4), 24 2023

  • The Comparative Accuracy of BISAP and PANC3 Scoring System for the Disease Severity and Outcome in Acute Pancreatitis in Tertiary Care Hospital from North India
    S Gupta, HS Dhillon, N Gupta
    Kathmandu Univ Med J 82 (2), 138-43 2023

  • To Compare Limb Strength, Core Strength, and Respiratory Endurance between Post-COVID-19 and Healthy Population: A Cross-Sectional Study
    P Pathak, S Sharma, N Gupta, D Shrestha, R Bala, RR Chinubhai
    Asian Journal of Pharmaceutical Research and Health Care 15 (2), 164-170 2023

  • Kocuria rosea Bacteremia in Chronic Kidney Disease Patient: A Rare Case Report.
    R Bala, N Kaur, N Gupta, U Narang
    Journal of Pure & Applied Microbiology 15 (3) 2021

  • Efficacy of Cyriax Physiotherapy versus Cyriax and low level Laser Therapy on pain and grip strength in Lateral Epicondylitis
    S Sharma, N Gupta, S Joshi, R Bala, R Sharma
    Bangladesh Journal of Medical Science 20 (2), 356-360 2021

  • Carbamazepine-associated drug reaction with eosinophilia and systemic symptoms syndrome
    A Sharma, E Joshi, N Gupta, M Joshi
    Journal of Pediatric Neurosciences 16 (1), 55-57 2021

  • Prevalence, multidrug-resistance and risk factors for AmpC β-lactamases producing Escherichia coli from hospitalized patients
    R Bala, VA Singh, N Gupta, P Rakshit
    The Journal of Infection in Developing Countries 14 (12), 1466-1469 2020

  • QTc prolongation in patients of cirrhosis and its relation with disease severity: An observational study from a rural teaching hospital
    A Bhardwaj, S Joshi, R Sharma, S Bhardwaj, R Agrawal, N Gupta
    Journal of Family Medicine and Primary Care 9 (6), 3020-3024 2020

  • Clinical Profile of Acute Kidney Injury in Intensive care unit: a prospective observational study from a rural tertiary care centre in North India
    S Jindal, S Joshi, R Sharma, CM Adya, N Gupta
    Bangladesh Journal of Medical Science 19 (4), 685-691 2020

  • Violence Against Doctors. Doctors: Earlier Demigods; Now Culprits?
    R Bala, N Gupta, S Kataria, S Lata, P Saini, R Garg
    Indian Journal of Public Health 11 (02), 837 2020

  • Evolution Proof-Antibiotics: A Hopeful Future to Combat Antibiotics Resistance
    N Gupta, R Bala, VA Singh, H Kumar, S Nagpal, S Mehta
    Indian Journal of Public Health 11 (02), 961 2020

  • In Vitro Study of Constitutive and Inducible Clindamycin Resistance in Staphylococcus aureus with Reference to Methicillin Resistant Staphylococcus aureus: Experience From
    S Lata, R Bala, N Jindal, N Gupta
    Indian Journal of Public Health 11 (02), 309 2020

  • Unilateral pure trigeminal motor neuropathy
    R Bala, N Gupta, S Joshi
    J Evol Med Dent Sci 9 (3), 166-167 2020

  • Medical student’s perception and feed-back on virtual classes during COVID-19 pandemic: a multi-centric questionnaire based study Introduction
    R Bala, N Gupta, R Sharma, U Narang, S Joshi, CN Navid
    Int J Health Clin Res 3 (4), 93-96 2020

  • Smoking and involvement of right coronary artery in ischemic heart disease
    A Rastogi, T Talwar, P Shah, N Gupta, VV Singh, S Manzoor
    Al Ameen Journal of Medical Sciences 13 (1), 49-52 2019

  • Preponderance of Inferior Wall Myocardial Infarction in Smokers with no other Cardiovascular Risk Factors
    SM Abhinav Rastogi, Pankaj Shah, Tejinder Talwar, Nitin Gupta, Vishal V Singh
    International Journal of Contemporary Medical Research 6 (9), 11-13 2019

  • Characterization and management of β- lactamases producing Escherichia coli causing complicated UTIs in an era of antimicrobial resistance
    Rosy Bala, Neeraja Jindal, Renu Bansal, Dr.Nitin Gupta
    International Journal of Medical Science and Innovative Research (IJMSIR) 4 2019

  • Cranio-vertebral junction anomaly–presenting as cervical myelopathy
    KK Singal, PD Gupta, N Gupta, J Aggarwal, VP Singh, P Malik, RF Khan
    International Journal of Human and Health Sciences (IJHHS) 3 (1), 40-42 2019

  • Preponderance of Inferior Wall Myocardial Infarction in Smokers with no other Cardiovascular Risk Factors
    A Rastogi, P Shah, T Talwar, N Gupta, VV Singh, S Manzoor
    RAMUS 2 (3), 0 2019

MOST CITED SCHOLAR PUBLICATIONS

  • Prevalence, multidrug-resistance and risk factors for AmpC β-lactamases producing Escherichia coli from hospitalized patients
    R Bala, VA Singh, N Gupta, P Rakshit
    The Journal of Infection in Developing Countries 14 (12), 1466-1469 2020
    Citations: 16

  • QTc prolongation in patients of cirrhosis and its relation with disease severity: An observational study from a rural teaching hospital
    A Bhardwaj, S Joshi, R Sharma, S Bhardwaj, R Agrawal, N Gupta
    Journal of Family Medicine and Primary Care 9 (6), 3020-3024 2020
    Citations: 11

  • Efficacy of Cyriax Physiotherapy versus Cyriax and low level Laser Therapy on pain and grip strength in Lateral Epicondylitis
    S Sharma, N Gupta, S Joshi, R Bala, R Sharma
    Bangladesh Journal of Medical Science 20 (2), 356-360 2021
    Citations: 8

  • Risk factors and demographic profile in acute myocardial infarction: a prospective study from tertiary care rural hospital in North India
    U Narang, A Gupta, S Gupta, N Gupta, S Joshi, S Sharma
    Journal of Contemporary Medical Research 5 (6), F14-21 2018
    Citations: 8

  • Efficacy of Combination Therapy of Rosuvastatin and Ezetimibe vs Rosuvastatin Monotherapy on Lipid Profile of Patients with Coronary Artery Disease.
    S Joshi, R Sharma, HK Rao, U Narang, N Gupta
    Journal of Clinical & Diagnostic Research 11 (12) 2017
    Citations: 6

  • Dreadful twins: twin unruptured aneurysms of bilateral intracranial arteries
    A Sharma, N Gupta, M Gupta, S Sharma
    Saudi Journal of Medicine & Medical Sciences 4 (3), 215-217 2016
    Citations: 4

  • Kocuria rosea Bacteremia in Chronic Kidney Disease Patient: A Rare Case Report.
    R Bala, N Kaur, N Gupta, U Narang
    Journal of Pure & Applied Microbiology 15 (3) 2021
    Citations: 3

  • Carbamazepine-associated drug reaction with eosinophilia and systemic symptoms syndrome
    A Sharma, E Joshi, N Gupta, M Joshi
    Journal of Pediatric Neurosciences 16 (1), 55-57 2021
    Citations: 3

  • Van der knaap disease: Megalencephalic leukoencephalopathy with subcortical cysts
    A Sharma, M Gupta, N Gupta, A Garg
    Saudi Journal of Medicine & Medical Sciences 4 (3), 238-239 2016
    Citations: 3

  • Mbius syndrome associated with neurofibromatosis Type 1: A rare co-occurrence
    A Sharma, N Gupta, T Talwar, M Gupta
    Journal of Pediatric Neurosciences 10 (2), 172-174 2015
    Citations: 3

  • In Vitro Study of Constitutive and Inducible Clindamycin Resistance in Staphylococcus aureus with Reference to Methicillin Resistant Staphylococcus aureus: Experience From
    S Lata, R Bala, N Jindal, N Gupta
    Indian Journal of Public Health 11 (02), 309 2020
    Citations: 2

  • Unilateral pure trigeminal motor neuropathy
    R Bala, N Gupta, S Joshi
    J Evol Med Dent Sci 9 (3), 166-167 2020
    Citations: 2

  • Medical student’s perception and feed-back on virtual classes during COVID-19 pandemic: a multi-centric questionnaire based study Introduction
    R Bala, N Gupta, R Sharma, U Narang, S Joshi, CN Navid
    Int J Health Clin Res 3 (4), 93-96 2020
    Citations: 2

  • Serum homocysteine as a risk factor for stroke: a prospective study from a rural tertiary care centre
    N Gupta, S Joshi, U Narang, R Bala, R Sharma, A Singla
    Asian J Pharm Clin Res 11 (11), 174-177 2018
    Citations: 2

  • BOSENTAN-endothelin receptor antagonist
    K Singal, N Singal, P Passi, M Singla, N Gupta, G Sumit
    Int J Human Health Sci 2018 3 (1), 10-13
    Citations: 2

  • Red cell distribution width as a marker of disease severity and in-hospital mortality in patients with st-segment elevation myocardial infarction
    R Raval, S Gupta, N Gupta, MA Bashar
    Indian Journal of Critical Care Medicine: Peer-reviewed, Official 2024
    Citations: 1

  • Violence Against Doctors. Doctors: Earlier Demigods; Now Culprits?
    R Bala, N Gupta, S Kataria, S Lata, P Saini, R Garg
    Indian Journal of Public Health 11 (02), 837 2020
    Citations: 1

  • Smoking and involvement of right coronary artery in ischemic heart disease
    A Rastogi, T Talwar, P Shah, N Gupta, VV Singh, S Manzoor
    Al Ameen Journal of Medical Sciences 13 (1), 49-52 2019
    Citations: 1