Shivangi Jaiswal
@jecrc university
Assistant Professor
Shivangi Jaiswal
RESEARCH, TEACHING, or OTHER INTERESTS
Organic Chemistry, Catalysis, Drug Discovery, Multidisciplinary
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Shivangi Jaiswal, Meenu Devi, Neetu Yaduvanshi, Smita Jain, Jaya Dwivedi, Dharam Kishore, Aleksey E. Kuznetsov, and Swapnil Sharma
Elsevier BV
Ruchika Sharma, Shivangi Jaiswal, Riya Chauhan, Manisha Bhardwaj, Kanika Verma, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Shivangi Jaiswal, Kanika Verma, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Neetu Yaduvanshi, Sanjana Tewari, Shivangi Jaiswal, Meenu Devi, Shruti Shukla, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Shivangi Jaiswal, Dharma Kishore, Annu Bhardwaj, Khushboo Bhardwaj, Shruti Richa, Smita Jain, Jaya Dwivedi, and Swapnil Sharma
Royal Society of Chemistry (RSC)
A water-assisted cascade reaction has been described to afford a new series of trifluoromethylated dipyridiodiazepinone derivatives as antibacterial agents. This methodology has a broad substrate scope with minimal waste generation.
Shivangi Jaiswal, Ruchika Sharma, Nirmala Kumari Jangid, and Jaya Dwivedi
Elsevier
Khushboo Bhardwaj, Shivangi Jaiswal, Annu Bhardwaj, Dharma Kishore, Jaya Dwivedi, and Swapnil Sharma
Bentham Science Publishers Ltd.
Abstract: Azepine is a privileged nitrogen-containing ring that has been found to display a wide range of biological activities. Azepine is a valuable skeleton in designing novel compounds in medicinal chemistry due to its interesting chemical and biological properties. The study on the synthesis of this ring system engenders a fascinating area of research owing to its potential to form an active pharmacophore for De Novo exploration. In this study, conventional and domino results were compared to access the diverse set of azepines in high yield. The domino approach has revolutionized the way through which the previously impossible yet significant transformations could be conceptualized, allowing the construction of difficult materials in one step. The aim of the present mini-review is to highlight the importance of the one-pot domino reaction for the synthesis of condensed azepines. This review also presents research on this subject from the past two decades.
Shivangi Jaiswal, Jaya Dwivedi, Dharma Kishore, and Swapnil Sharma
Bentham Science Publishers Ltd.
Abstract: Tetrazole is a most versatile pharmacophore of which more than twenty FDAapproved drugs have been marketed globally for the management of various diseases. In spite of many remarkable and consistent efforts having been made by the chemists towards the development of greener and sustainable strategies for the synthesis of tetrazole derivatives, this approach still needs more attention. The present review focuses on the green synthetic approach for the preparation of tetrazole derivatives from different starting materials such as nitrile, isonitrile, carbonyl, amine, amide, oxime and terminal alkyne functions. The mechanism of tetrazole synthesis from different substrates is discussed. In addition to this, a four component Ugi-azide reaction to the tetrazole synthesis is also described. Of note, the present articles exploited several water-mediated and solvent-free methodologies for tetrazole synthesis. The important key features of tetrazole synthesis were pinpointing in each synthetic scheme which provides excellent guide to those searching for selective procedure to achieve the desired transformation. This review seeks to present a timely account (2011-2023) on the splendid array of ecofriendly procedures of synthesis known today for the preparation of tetrazole derivatives from different starting materials. The rational of this review is to enlighten recent advancements in the synthesis of tetrazole derivatives from different substrates.
Shivangi Jaiswal, Nikhilesh Arya, Neetu Yaduvanshi, Meenu Devi, Sonika Jain, Smita Jain, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Neetu Yaduvanshi, Meenu Devi, Sanjana Tewari, Shivangi Jaiswal, Sonia Zeba Hashmi, Shruti Shukla, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Jigar Panchal, Shivangi Jaiswal, Sonika Jain, Jyoti Kumawat, Ashima Sharma, Pankaj Jain, Smita Jain, Kanika Verma, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Akansha Bisht, Shruti Richa, Shivangi Jaiswal, Jaya Dwivedi, and Swapnil Sharma
CRC Press
Meenu Devi, Shivangi Jaiswal, Neetu Yaduvanshi, Sonika Jain, Smita Jain, Kanika Verma, Rahul Verma, Dharma Kishore, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Neetu Yaduvanshi, Shivangi Jaiswal, Sanjana Tewari, Shruti Shukla, Saikh Mohammad Wabaidur, Jaya Dwivedi, and Swapnil Sharma
Elsevier BV
Meenu Devi, Shivangi Jaiswal, Neetu Yaduvanshi, Navjeet Kaur, Dharma Kishore, Jaya Dwivedi, and Swapnil Sharma
Wiley
Shalu Sain, Shivangi Jaiswal, Sonika Jain, Namita Misra, Anamika Srivastava, Ra Jendra, Dharma Kishore, Jaya Dwivedi, Saikh Mohammad Wabaidur, Mohammad Ataul Islam,et al.
Wiley
A new series of thieno nucleus embellished trinuclear (19, 20) and tetranuclear (21-24) nitrogen heteroaryl have been synthesized by the Suzuki cross-coupling reaction using bis-(triphenylphosphine) palladium (ll) dichloride. All the synthesized compounds were characterized by IR, 1HNMR, 13CNMR and Mass spectral properties. In vitro antibacterial studies of the synthesized compound were conducted using broth microdilution assay employing gram-positive and gram negative strains and half-maximal inhibitory concentration (IC50) was determined. The result showed that compound 20 possess best antibacterial activity against S. aureus and E. coli with IC50 values of 60 μg mL-1 and 90 μg mL-1. Further to determine the mode of antibacterial action, compounds 20 and 21 were examined for in vitro bacterial dehydrogenase inhibitory assay. To understand the binding affinity of the synthesized compounds, the docking study was performed in the bacterial dehydrogenase enzyme by AutoDock Vina software and structure was confirmed by Discovery Studio Visualizer. All the synthesized compounds were docked in a good manner within the active sites of the bacterial dehydrogenase enzyme and exhibited good binding energies.
Shivangi Jaiswal, Meenu Devi, Neha Sharma, Komal Rathi, Jaya Dwivedi, and Swapnil Sharma
Informa UK Limited
Meenu Devi, Shivangi Jaiswal, Sonika Jain, Navjeet Kaur, and Jaya Dwivedi
Bentham Science Publishers Ltd.
Nitrogen-containing heterocycles attract the attention of chemists due to their multifarious activities. Amongst all, pyrimidine plays a central role and exhibits a broad spectrum of biological activities. Literature is replete with various aspects of synthetic development in the chemistry of pyrimidine for a wide array of applications. It aroused our interest to compile various novel and efficient synthetic approaches towards the synthesis of pyrimidine and its derivatives. Pyrimidine derivatives are broadly useful as therapeutic agents, owing to their high degree of structural diversity. They have been recorded to possess a diverse range of therapeutic activities viz. anticancer, anti-inflammatory, anti-HIV etc.
Meenu Devi, Shivangi Jaiswal, Jaya Dwivedi, and Navjeet Kaur
Bentham Science Publishers Ltd.
The present review focuses on the synthesis of two heteroatoms containing sixmembered heterocyclic compounds, i.e., pyrimidine. In this review, a number of pyrimidine derivatives have been illustrated, which show the exceptional ability towards clinical practices. Pyrimidine derivatives show antimicrobial, antibacterial, antifungal, antiallergic, antiinflammatory, anticancer, and anticonvulsant activities. Therefore, researchers are encouraged to synthesize novel, potent, safe, and selective pyrimidine derivatives that are effective against the mutant strains, and the development of synthetic protocols is a high priority in medicinal chemistry research. Many methodologies have been developed for the preparation of pyrimidine derivatives. In this review article, the synthetic strategies of pyrimidine derivatives are classified into metal-catalyzed synthesis, ionic-liquid assisted synthesis, microwave-assisted synthesis, and solid-phase synthesis.