Agricultural and Biological Sciences, Biotechnology, Molecular Biology, Biochemistry, Genetics and Molecular Biology
10
Scopus Publications
554
Scholar Citations
13
Scholar h-index
16
Scholar i10-index
Scopus Publications
Advancements in Strain Development and Genetic Engineering for Cellulase Production: A Systematic Review Navneet Sharma, Deepali Aggarwal, Sheelendra Mangal Bhatt Journal of Environmental Nanotechnology, 2025 Strains, defined as subtypes or genetic variants of microorganisms, are selectively developed at an industrial scale to enhance the production of cellulases and other metabolites. These strains, bacterial or fungal, are genetically engineered to improve traits such as rapid growth, genetic stability, productivity, and ease of cultivation. Genetic modifications are typically aimed at increasing or altering gene expression to maximize output. Cellulases are enzymes that catalyze the breakdown of cellulose into simpler sugars, enabling its conversion into biofuels and other value-added products. In particular, bacterial cellulose produced by Acetobacteraceae is recognized for its purity, biocompatibility, and natural origin, making it highly suitable for applications in material science. To further enhance cellulase yields, researchers identify and utilize strains capable of high productivity under low-nitrogen conditions. Recombinant DNA technology is employed to sequence genomes, introduce genetic constructs, and express target proteins in host cells. In fungal systems, advanced approaches such as the Reconstruction of Expression Regulatory Network (REXRN) have been applied to fine-tune gene expression and enhance the production of cellulase enzymes involved in cellulose degradation. Together, these strategies support the development of high-performance microbial strains for industrial biotechnology applications.
A Comprehensive Review on the Role of Gymenma sylvestre in Combating Diabetes-2 S. M. Bhatt, Navneet Sharma Journal of Natural Remedies, 2024 The current review focuses on a detailed comprehensive role of Gymnema sylvestre (GS) and other herbs for their Ayurvedic impact in controlling blood sugar by releasing insulin from the pancreas in diabetic Type 2. G. sylvestre (GS) supplementation has also been seen to leave an impact on various cardiovascular risk factors and improves the lipid profile, blood pressure, anthropometric indices, and control of glycemia. Additionally, extracts of Gymnema have been shown to have an inhibitory impact on triglyceride accumulation in muscles and the liver, while reducing the buildup of fatty acids in the bloodstream, thus also reducing HB1C parameters. In the current review, we have also discussed information about Gymnemic acid structure isolation their sources, their clinical effects in diabetic control in Type 1 and Type 2, and clinical effects over the humans and mice signalling as immunomodulators.
A critical review on nano-food packaging and its applications Sheelendra M BHATT Journal of Commercial Biotechnology, 2020 The present manuscript addresses the effect of nanotechnology in various food sectors. Increasedfood functionality, enhanced flavor, reduced delivery of food additives are some of theappealing choices raising plausibility of high health advantages hypothesized in future. At theface of explosion of information, it is important to monitor them in a brief and updated manner.In this manner, new nanomaterials like carbon nanotubes, nano-biopolymers have diverseapplications in food packaging, good food release property with enhanced food safety features.Furthermore, nano-encapsulation of probiotics, nano applications in food processing sector andother related issues, new functional nanomaterials for use in food along with their propertieshave been talked about in this review paper.
Comparative analysis of antioxidant properties of different medicinal and non-medicinal plants Research Journal of Pharmaceutical Biological and Chemical Sciences, 2015
Lignocellulosic feedstock conversion, inhibitor detoxification and cellulosic hydrolysis - A review Sheelendra M. Bhatt, Shilpa Biofuels, 2014 The current review is an attempt to cover various pre-treatment strategies such as physical, chemical, organosolve and biological pre-treatment in order to change the crystallinity of lignocellulosic biomass along with methods and strategies for inhibitor detoxification for improving the cellulose hydrolysis and fermentation. The presence of lignin in lignocellulosic biomass is the biggest hurdle and therefore a judicial pre-treatment selection technique is important, based on lignocellulosic mass composition analysis for improving overall saccharification. The production of inhibitors during pre-treatment is another cause of low saccharification owing to deactivation of cellulase enzyme. In this review a comprehensive discussion has been made of the impact of various pre-treatment strategies on overall hydrolysis and saccharification in view of the varied composition of lignocellulosic biomass. Various detoxification approaches have also been discussed, along with the economical bioprocessing issue, and their advantages and disadvantages. Bio refinery approaches have been important in this regard to make bioethanol production more economical.
Bioethanol production from economical agro waste (Groundnut Shell) in SSF mode Research Journal of Pharmaceutical Biological and Chemical Sciences, 2014
Optimization studies of alkaline cellulase from bacillus licheniformis sm1 isolated from rice agricultural soil using taguchi methodology Sheelendra M. Bhatt, Pankaj Lakhwan, Shilpa Shilpa Biosciences Biotechnology Research Asia, 2014 The aim of the present work was to screen microbes related to alkaline cellulase production from rhizosphere of rice field soil from Phagwara, Punjab. Out of 9 isolates screened, isolate 6 th designated as SM1 was selected for alkaline cellulase study. Results of 16S rRNA revealed this strain as Bacillus licheniformis. Various medium conditions affecting cellulase activity such as pH, C/N ratio, Tween-20 and lactose were optimized using L9 conditions by Taguchi methodology in submerged conditions. Factors having significant impact over alkaline cellulase activity were in order pH > C/N ratio > Tween20 > Lactose. The most optimum conditions for cellulase production was pH 9; C/N, 1:2; Lactose, 1 % (w/v) and Tween 20, 1 %(v/v) at 50 0C.
RECENT SCHOLAR PUBLICATIONS
THE WHEAT MARKER FOR BETTER YIELD AND HEAT STRESS TOLERANCE: A REVIEW SHM BHATT, PK Saini, R Bahadur, A Singh JOURNAL OF AGRICULTURE BIOTECHNOLOGY & APPLIED SCIENCES Учредители … , 2025 2025
The potential of various herbal plants for potential therapeutic treatment for diabetes management SM Bhatt, N Sharma Annals of the National Academy of Medical Sciences (India) 61 (3), 213 , 2025 2025 Citations: 2
Study on anaerobic co-digestion of cow dung and fruit waste for biogas production A Phillip, S Bhatt, N Sharma Biological Reviews 2 (2), 121-129 , 2025 2025 Citations: 2
circular economy S Bhatt, N SHARMA Journal of Agriculture Biotechnology & Applied Sciences 3 (1) , 2025 2025
THE DNA MODIFYING ENZYMES USED IN BIOTECHNOLOGY SH BHATT JOURNAL OF AGRICULTURE BIOTECHNOLOGY & APPLIED SCIENCES Учредители … , 2025 2025
EARTHWORMS AS A BIO INDICATOR FOR ASSESS-ING SOIL TOXICITY: A REVIEW ON IMPACT IN AGRI-CULTURE Jain Pragati, Singh Amisha, Sharma Ananya Journal of Agriculture Biotechnology & applied sciences (JABAAS) 2 (3), 120-135, , 2024 2024
Enhanced biogas production using anaerobic co-digestion of animal waste and food waste: A review A Phillip, SM Bhatt, N Sharma, B Poudel Journal of Scientific Research and Reports 30 (8), 761-781 , 2024 2024 Citations: 17
Economical Cellulase Production under Optimized condition in Batch condition using Water Hyacinth (WH) Waste SM Bhatt Sciences 1 (1), 11-21 , 2023 2023
Microbial production of bio plastics SM Bhatt, SM BHATT, MPOF BIOPLASTICS Journal of Agriculture Biotechnology and Applied Sciences 1 (1), 1-4 , 2023 2023 Citations: 2
Recent trend in Bio-fortified wheat production-A review SM Bhatt Journal of Agriculture Biotechnology & Applied Sciences. Vol 1 (1), 22-27 , 2023 2023
Nutritional Prospects in Wheat Bio-Fortification SM Bhatt, A Jahan KMICS Journal of Sciences 1 (1), 1-9 , 2023 2023
Nutritional Prospects in Bio-Fortified Wheat SMBA jahan2 KMICS Journal of Sciences 1 (1), 1-9 , 2023 2023
pharmaceutical biotechnology SM Bhatt 2023
Challenges Assessment in Economic Algal Biofuel Production SM Bhatt Technological Advancement in Algal Biofuels Production, 129-147 , 2022 2022
Extremophiles in Aviation Biofuel Production SM Bhatt Extremophiles: General and Plant Biomass Based Biorefinery, 202 , 2022 2022
Biogas from kitchen waste SM Bhatt Food waste to green fuel: trend & development, 153-164 , 2022 2022 Citations: 2
Morphological variation of electrocardiogram: A boon in diagnosis of canine cardiac disorders KK Sahoo, D Gupta, A Tiwari, S Rai, A Sawhney, P Sharma, S Sahu, ... The Pharma Innovation Journal 11 (1199-1202), 4 , 2022 2022 Citations: 5
Economical biofuel production strategies from biomass biowaste SM Bhatt, S Bhatt, A Bakshi Bioenergy research: integrative solution for existing roadblock, 1-22 , 2021 2021 Citations: 4
Microbial Cellulolytic‐Based Biofuel Production SM Bhatt Bioenergy Research: Evaluating Strategies for Commercialization and … , 2021 2021
A textbook of molecular biotechnology AK Chauhan, A Varma IK International Pvt Ltd , 2009 2009.0 Citations: 50
Shilpa, 2014 SM Bhatt, P Lakhwan Lignocellulosic feedstock conversion, inhibitor detoxification and … , 0 Citations: 48
Challenges in Enzymatic Route of Mannitol Production SM Bhatt, A Mohan, SK Srivastava http://www.hindawi.com/isrn/biotechnology/2013/914187/, 1-13 , 2013 2013.0 Citations: 46
Assessment of synthetic milk exposure to children of selected population in Uttar Pradesh, India SA BHATT, S M, Bhatt S R ANVISHIKI 7 (1), 1-16 , 2009 2009.0 Citations: 33
Lactic Acid Production from Cane Molasses by Lactobacillus delbrueckii NCIM 2025 in Submerged Condition: Optimization of Medium Component by Taguchi DOE … SM Bhatt, SK Srivastava Food biotechnology 22 (2), 115-139 , 2008 2008.0 Citations: 29
Biofuel production technologies: critical analysis for sustainability N Srivastava, M Srivastava, PK Mishra, VK Gupta Springer , 2020 2020.0 Citations: 24
Method development and validation of UV spectrophotometric method for the quantitative estimation of curcumin in simulated nasal fluid S Sharma, JB Sharma, S Bhatt, M Kumar Drug Research 70 (08), 356-359 , 2020 2020.0 Citations: 23
Bioethanol production from economical agro waste (groundnut shell) in SSF mode. SM Bhatt, S Shilpa 2014.0 Citations: 23
Sustainable approaches for biofuels production technologies: from current status to practical implementation N Srivastava, M Srivastava, PK Mishra, SN Upadhyay, PW Ramteke, ... Springer , 2018 2018.0 Citations: 20
Enhanced biogas production using anaerobic co-digestion of animal waste and food waste: A review A Phillip, SM Bhatt, N Sharma, B Poudel Journal of Scientific Research and Reports 30 (8), 761-781 , 2024 2024.0 Citations: 17
Bioprocessing perspective in biorefineries SM Bhatt, JS Bal Sustainable approaches for biofuels production technologies: from current … , 2018 2018.0 Citations: 15
Impact of media and education on food practices in urban area of Varanasi SR Bhatt, SM Bhatt, A Singh National Journal of Community Medicine 3 (04), 581-588 , 2012 2012.0 Citations: 15
Approaches to enhance industrial production of fungal cellulases M Srivastava, N Srivastava, PW Ramteke, PK Mishra Springer International Publishing , 2019 2019.0 Citations: 13
Biosorption of Arsenic (III) from drinking water by using low cost biosorbents derived from peels of Oranges, Turnip and Peanut shells M Sidhu, P Sama, J Parmar, SM Bhatt International Journal of Pharmaceutical Research & Drug Development 1 (1), 16-21 , 2014 2014.0 Citations: 13
Highly sensitive & low cost colorimetric method for quantifying arsenic metal in drinking water of Malwa Punjab and comparison with ICAP-AES M Sidhu, P Mahajan, SM Bhatt annals of biological research 5 (3), 105 , 2014 2014.0 Citations: 12
A Critical Review On Nano-Food Packaging and Its Applications SM Bhatt Journal of Commercial Biotechnology 25 (3), 3-17 , 2020 2020.0 Citations: 9
Food adulteration and practices in urban area of Varanasi– SMB ANITA SINGH, SUCHI RAI Food Science Research Journal 1 (2), 183-195 , 2010 2010.0 Citations: 9
book : Animal cell culture: concept and application SM Bhatt Alpha Science International http://www.ncbi.nlm.nih.gov/nlmcatalog/101574607 … , 2011 2011.0 Citations: 8
Enzymology and Enzyme Technology SM BHATT Enzymology and Enzyme Technology, ISBN 81-219-3584-9-2011, , 2010 2010.0 Citations: 7
