Eduardo Kloppel

@fgu.cas.cz

Mitochondrial physiology
Czech Academy of Sciences

RESEARCH INTERESTS

Diabetes and mitochondrial metabolism
145

Scholar Citations

6

Scholar h-index

5

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Details of superoxide formation upon branched-chain keto-acid beta-like-oxidation leading to insulin secretion in INS-1E cells
    P Jezek, E Kloppel, H Engstova, J Tauber, P Duspiva, M Jaburek
    Free Radical Biology and Medicine 240, S19-S19 , 2025
    2025
  • Electron-transfer flavoprotein: ubiquinone-oxidoreductase induces increased superoxide formation upon fatty acid and branched-chain keto-acid Beta-oxidation in INS-1E cells: 54
    E Kloppel, H Engstova, P Pruchova, M Jaburek, P Jezek
    Free Radical Biology and Medicine 224, S28-S29 , 2024
    2024
  • Mitochondrial redox signals upon insulin secretion stimulated by branched-chain keto acids: 48
    P Jezek, E Kloppel, P Pruchova, H Engstova, M Jaburek
    Free Radical Biology and Medicine 224, S26 , 2024
    2024
  • Redox signaling upon SS-like oxidation of branched-chain keto acids essentially stimulates insulin secretion in pancreatic SS-cells
    E Kloppel, P Pruchova, J Tauber, H Engstova, M Jaburek, P Jezek
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1865, 108-108 , 2024
    2024
  • Redox signaling upon β-like oxidation of branched-chain keto acids essentially stimulates insulin secretion in pancreatic β-cells
    E Klöppel, P Průchová, J Tauber, H Engstová, M Jabůrek, P Ježek
    Biochimica et Biophysica Acta (BBA)-Bioenergetics 1865, 149392 , 2024
    2024
  • Mitochondrial fatty acid β-oxidation is an essential component of fatty acid-stimulated insulin secretion
    M Jabůrek, P Průchová, E Klöppel, J Tauber, P Ježek
    Biochimica et Biophysica Acta (BBA)-Bioenergetics 1865, 149387 , 2024
    2024
  • Mitochondria to plasma membrane redox signaling is essential for fatty acid β-oxidation-driven insulin secretion
    M Jabůrek, E Klöppel, P Průchová, O Mozheitova, J Tauber, H Engstová, ...
    Redox Biology 75, 103283 , 2024
    2024
    Citations: 13
  • Mitochondrial physiology of cellular redox regulations
    P Ježek, A Dlaskova, H Engstova, J Špačková, J Tauber, P Průchová, ...
    Physiological Research 73 (Suppl 1), S217 , 2024
    2024
    Citations: 15
  • Insulin signaling and mitochondrial phenotype of skeletal muscle are programmed in utero by maternal diabetes
    E Klöppel, LL Cruz, LFL Prado-Souza, A Eckhardt, JE Corrente, ...
    Molecular and Cellular Endocrinology 588, 112199 , 2024
    2024
    Citations: 2
  • Mitochondrial redox signals are essential for insulin secretion
    P Jezek, M Jaburek, E Kloeppel, P Pruchova, H Engstova, A Dlaskova
    Free Radical Biology and Medicine 208, S20 , 2023
    2023
  • Amplex Red-based H2O2 Assay Detects Mitochondrial Redox Signals During Insulin Secretion
    M Jaburek, P Pruchova, E Kloeppel, H Engstova, P Jezek
    Free Radical Biology and Medicine 208, S19-S20 , 2023
    2023
    Citations: 1
  • Do Non-Metabolizable Agonist of GPR40 Receptor Require Elevated H2O2 To Stimulate Insulin Secretion?
    P Pruchova, M Jaburek, E Kloeppel, O Mozheitova, H Engstova, P Jezek
    Free Radical Biology and Medicine 208, S27-S28 , 2023
    2023
  • Calcium supplementation on glucose tolerance, oxidative stress, and reproductive outcomes of diabetic rats and their offspring
    E Klöppel, MR Souza, VS Barco, FQ Gallego, YK Sinzato, JE Corrente, ...
    Reproductive Sciences 30 (9), 2813-2828 , 2023
    2023
    Citations: 2
  • Benefits of vitamin D supplementation on pregnancy of rats with pregestational diabetes and their offspring
    E Klöppel, YK Sinzato, T Rodrigues, FQ Gallego, B Karki, GT Volpato, ...
    Reproductive Sciences 30 (4), 1241-1256 , 2023
    2023
    Citations: 6
  • Comparison of streptozotocin-induced diabetes at different moments of the life of female rats for translational studies
    YK Sinzato, E Klöppel, CA Miranda, VG Paula, LF Alves, LLS Nascimento, ...
    Laboratory Animals 55 (4), 329-340 , 2021
    2021
    Citations: 36
  • Repercussion of Maternal Diabetes and Post-Weaning High-Fat Diet Consumption in Laboratory Animals
    VG Paula, YK Sinzato, RQM Souza, LL Cruz, E Kloppel, ...
    Metabolism-Clinical and Experimental 116 , 2021
    2021
  • Repercussions of low fructose-drinking water in male rats
    CA Miranda, TE Schönholzer, E Klöppel, YK Sinzato, GT Volpato, ...
    Anais da Academia Brasileira de Ciências 91, e20170705 , 2019
    2019
    Citations: 27
  • Vitamina D e cálcio para o tratamento de ratas prenhes com diabete moderado
    E Klöppel
    Universidade Estadual Paulista (Unesp) , 2018
    2018
  • Effect of the induction of transgenerational obesity on maternal-fetal parameters
    TS Soares, AP Andreolla, CA Miranda, E Klöppel, LS Rodrigues, ...
    Systems biology in reproductive medicine 64 (1), 51-59 , 2018
    2018
    Citations: 43
  • Evaluation of metabolic profile and renal function of treatment of Duguetia furfuracea aqueous extract in obese female Wistar rats
    D de Souza Almeida, DLA dos Santos, AZ Schavinski, AL Deluque, ...
    Diabetology & Metabolic Syndrome 7 (Suppl 1), A126 , 2015
    2015

MOST CITED SCHOLAR PUBLICATIONS

  • Effect of the induction of transgenerational obesity on maternal-fetal parameters
    TS Soares, AP Andreolla, CA Miranda, E Klöppel, LS Rodrigues, ...
    Systems biology in reproductive medicine 64 (1), 51-59 , 2018
    2018
    Citations: 43
  • Comparison of streptozotocin-induced diabetes at different moments of the life of female rats for translational studies
    YK Sinzato, E Klöppel, CA Miranda, VG Paula, LF Alves, LLS Nascimento, ...
    Laboratory Animals 55 (4), 329-340 , 2021
    2021
    Citations: 36
  • Repercussions of low fructose-drinking water in male rats
    CA Miranda, TE Schönholzer, E Klöppel, YK Sinzato, GT Volpato, ...
    Anais da Academia Brasileira de Ciências 91, e20170705 , 2019
    2019
    Citations: 27
  • Mitochondrial physiology of cellular redox regulations
    P Ježek, A Dlaskova, H Engstova, J Špačková, J Tauber, P Průchová, ...
    Physiological Research 73 (Suppl 1), S217 , 2024
    2024
    Citations: 15
  • Mitochondria to plasma membrane redox signaling is essential for fatty acid β-oxidation-driven insulin secretion
    M Jabůrek, E Klöppel, P Průchová, O Mozheitova, J Tauber, H Engstová, ...
    Redox Biology 75, 103283 , 2024
    2024
    Citations: 13
  • Benefits of vitamin D supplementation on pregnancy of rats with pregestational diabetes and their offspring
    E Klöppel, YK Sinzato, T Rodrigues, FQ Gallego, B Karki, GT Volpato, ...
    Reproductive Sciences 30 (4), 1241-1256 , 2023
    2023
    Citations: 6
  • Insulin signaling and mitochondrial phenotype of skeletal muscle are programmed in utero by maternal diabetes
    E Klöppel, LL Cruz, LFL Prado-Souza, A Eckhardt, JE Corrente, ...
    Molecular and Cellular Endocrinology 588, 112199 , 2024
    2024
    Citations: 2
  • Calcium supplementation on glucose tolerance, oxidative stress, and reproductive outcomes of diabetic rats and their offspring
    E Klöppel, MR Souza, VS Barco, FQ Gallego, YK Sinzato, JE Corrente, ...
    Reproductive Sciences 30 (9), 2813-2828 , 2023
    2023
    Citations: 2
  • Amplex Red-based H2O2 Assay Detects Mitochondrial Redox Signals During Insulin Secretion
    M Jaburek, P Pruchova, E Kloeppel, H Engstova, P Jezek
    Free Radical Biology and Medicine 208, S19-S20 , 2023
    2023
    Citations: 1
  • Details of superoxide formation upon branched-chain keto-acid beta-like-oxidation leading to insulin secretion in INS-1E cells
    P Jezek, E Kloppel, H Engstova, J Tauber, P Duspiva, M Jaburek
    Free Radical Biology and Medicine 240, S19-S19 , 2025
    2025
  • Electron-transfer flavoprotein: ubiquinone-oxidoreductase induces increased superoxide formation upon fatty acid and branched-chain keto-acid Beta-oxidation in INS-1E cells: 54
    E Kloppel, H Engstova, P Pruchova, M Jaburek, P Jezek
    Free Radical Biology and Medicine 224, S28-S29 , 2024
    2024
  • Mitochondrial redox signals upon insulin secretion stimulated by branched-chain keto acids: 48
    P Jezek, E Kloppel, P Pruchova, H Engstova, M Jaburek
    Free Radical Biology and Medicine 224, S26 , 2024
    2024
  • Redox signaling upon SS-like oxidation of branched-chain keto acids essentially stimulates insulin secretion in pancreatic SS-cells
    E Kloppel, P Pruchova, J Tauber, H Engstova, M Jaburek, P Jezek
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1865, 108-108 , 2024
    2024
  • Redox signaling upon β-like oxidation of branched-chain keto acids essentially stimulates insulin secretion in pancreatic β-cells
    E Klöppel, P Průchová, J Tauber, H Engstová, M Jabůrek, P Ježek
    Biochimica et Biophysica Acta (BBA)-Bioenergetics 1865, 149392 , 2024
    2024
  • Mitochondrial fatty acid β-oxidation is an essential component of fatty acid-stimulated insulin secretion
    M Jabůrek, P Průchová, E Klöppel, J Tauber, P Ježek
    Biochimica et Biophysica Acta (BBA)-Bioenergetics 1865, 149387 , 2024
    2024
  • Mitochondrial redox signals are essential for insulin secretion
    P Jezek, M Jaburek, E Kloeppel, P Pruchova, H Engstova, A Dlaskova
    Free Radical Biology and Medicine 208, S20 , 2023
    2023
  • Do Non-Metabolizable Agonist of GPR40 Receptor Require Elevated H2O2 To Stimulate Insulin Secretion?
    P Pruchova, M Jaburek, E Kloeppel, O Mozheitova, H Engstova, P Jezek
    Free Radical Biology and Medicine 208, S27-S28 , 2023
    2023
  • Repercussion of Maternal Diabetes and Post-Weaning High-Fat Diet Consumption in Laboratory Animals
    VG Paula, YK Sinzato, RQM Souza, LL Cruz, E Kloppel, ...
    Metabolism-Clinical and Experimental 116 , 2021
    2021
  • Vitamina D e cálcio para o tratamento de ratas prenhes com diabete moderado
    E Klöppel
    Universidade Estadual Paulista (Unesp) , 2018
    2018
  • Evaluation of metabolic profile and renal function of treatment of Duguetia furfuracea aqueous extract in obese female Wistar rats
    D de Souza Almeida, DLA dos Santos, AZ Schavinski, AL Deluque, ...
    Diabetology & Metabolic Syndrome 7 (Suppl 1), A126 , 2015
    2015