Professor assistente Doutor e pesquisador da Faculdade de Ciências e Engenharia, da Universidade Estadual Paulista de Tupã. É bacharel e licenciado em Ciências Biologias (2004 - 2007). Neste período desenvolveu projeto de iniciação científica no Instituto de Química de Araraquara - Unesp no departamento de Química Analítica. Tem mestrado em Zootecnia, Área: Nutrição animal, pela Universidade Estadual Paulista Júlio de Mesquita Filho - Unesp (2008-2010), doutorado em Biologia Geral e Aplicada, Área: Biomoléculas, pela Universidade Estadual Paulista Júlio de Mesquita Filho - Unesp (2010-2013) e pós doutorado – PNPD, no Instituto de Química da Universidade Federal do Mato Grosso do Sul. Tem experiência em Química Analítica Ambiental, Ecologia Aplicada e Bioquímica (impacto ambiental, coleta e preparo de amostras de interesse ambiental; fracionamento e caracterização de proteínas e metaloproteínas por eletrofores 2D-PAGE e espectrometria de massas; quantificação de elementos traços por espectrometria de absorção atômica e espectrometria de fluorescência atômica)
EDUCATION
Pós-Doutorado. Universidade Federal de Mato Grosso do Sul, UFMS, Brasil.
Doutorado em Biologia Geral e Aplicada. Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, Brasil.
Mestrado em Zootecnia. Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, Brasil.
Graduação em Ciências Biológicas. Universidade de Araraquara, UNIARA, Brasil.
RESEARCH INTERESTS
Metalômica
Química Ambiental
28
Scopus Publications
831
Scholar Citations
16
Scholar h-index
25
Scholar i10-index
Scopus Publications
Refuse-Derived Fuel with the Addition of Peanut Shells: An Evaluation Using a Decision-Making Support Algorithm Natália Dadario, Mário Mollo Neto, Felipe André dos Santos, Luís Roberto Almeida Gabriel Filho, Camila Pires Cremasco Energies, 2025 Brazil has made progress in Municipal Solid Waste (MSW) management through national legislation focused on integrated waste handling. However, challenges persist, particularly regarding MSW overproduction. A sustainable alternative is Refuse-Derived Fuel (RDF), generated from MSW with or without biomass addition. To be viable for combustion, RDF must meet established energy and environmental quality standards. In this context, a mathematical model based on fuzzy logic was developed to classify RDF quality and support decision-making. Five RDF samples were tested, evaluating their Lower Heating Value (LHV), chlorine, and mercury contents using calorimetry, atomic absorption, and X-ray fluorescence. Results indicate that RDF produced solely from MSW tends to have inadequate LHV, necessitating drying pretreatment. Even with the addition of peanut shells, the highest classification achieved was “Regular”, suggesting limited suitability for combustion in furnaces or boilers without pretreatment. Since the general composition of MSW in Brazil is consistent with the characteristics analyzed, RDF may remain unviable for energy recovery under similar conditions. Economic feasibility studies on drying are recommended, especially in urban centers with limited landfill space.
Electrochemical Processes Used to Degrade Thiamethoxam in Water and Toxicity Analyses in Non-Target Organisms Juliane C. Forti, Pedro E. M. Robles, Yasmin S. Tadayozzi, Maiara A. F. Demori, Felipe A. Santos, et al. Processes, 2024 Pesticides ensure greater productivity in less time; however, they spread beyond the perimeters to which they are applied to reach non-target organisms, thereby affecting plant, animal, and human health. Thiamethoxam (TMX) is considered to be one of the main agents responsible for poisoning bees and potentially contaminating surface and groundwater. Conventional water-treatment protocols are unable to degrade thiamethoxam; therefore, electrochemically advanced oxidative processes (EAOPs) have become promising alternatives owing to their ease of operation and cost-effectiveness. Herein, we examined the use of EAOPs to oxidize thiamethoxam in commercial Actara® and analyzed treatment efficiencies through phytotoxicity studies using cucumber and maize seeds as bioindicators. In addition, the cost of each process was analyzed based on the resulting current efficiency. The treated solutions were used to germinate seeds that were analyzed for total protein, hydrogen peroxide, lipid peroxidation (MDA), superoxide dismutase (SOD), and catalase (CAT) activities. EAOPs were found to effectively oxidize TMX, with more than 50% degraded and 80% COD removed under all treatment conditions, even when the commercial product was used. The photoelectro-Fenton process using 10 mg L−1 FeSO4 and 100 mg L−1 H2O2 exhibited the best results, with 79% of the TMX degraded and 83% of the COD removed, additionally exhibiting the lowest estimated operating cost (USD 1.01 dm−3). Higher enzymatic SOD and CAT activities, total protein content, and H2O2 concentration were observed; however, no significant changes in MDA were recorded. This treatment protocol effectively oxidizes TMX and reduces its phytotoxicity in maize and cucumber seedlings.
Relationship of the “Dequada” Phenomenon with Mercury Methylation in Pantanal, Brazil Glaucia A. Nunes, Dayana D. Ramos, Juliane C. Forti, Diovany D. Ramos, Lincoln C. S. Oliveira, et al. Water Switzerland, 2024 The illegal activity of gold mining in the Brazilian Pantanal is contaminating the aquatic ecosystem with mercury. This contamination has been potentiated by mercury methylation due to a typical natural phenomenon of the Pantanal ecosystem known as “dequada”. The present study estimated in the laboratory the temporal production of methylmercury at two timepoints: the beginning of a flood, when the “dequada” phenomenon occurs, and the dry season without such phenomenon. After collecting water and sediment, experiments were performed with microcosms to reproduce conditions close to nature. To monitor the concentration of methylmercury, 1.0 mg L−1 of Hg2+ was added to water and sediment experiments in the Castelo and Saracura bays, both during the “dequada” and without it; monitoring lasted for 25 days. The methylmercury concentration was analyzed using atomic fluorescence spectrometry, total organic carbon using TOC 5000A, and physical and chemical parameters such as pH, redox potential, and dissolved oxygen with a multi-parameter probe. The results led to the conclusion that the “dequada” phenomenon significantly affected mercury methylation, because the environmental changes caused by this phenomenon such as the increased concentration of organic matter, decreased dissolved oxygen, and decreased pH, potentiated mercury methylation. During the “dequada” in the Castelo bay, the methylation rate was 3.5 times higher (6297.56 ng L−1) than in the experiment without the “dequada” (1827.44 ng L−1). Therefore, the gold mining activity in Pantanal can cause great damage to the ecosystem because this environment favors mercury methylation, making its most toxic form active in the aquatic ecosystem of Pantanal.
Waste-to-Energy Recovery from Municipal Solid Waste: Global Scenario and Prospects of Mass Burning Technology in Brazil Natália Dadario, Luís Roberto Almeida Gabriel Filho, Camila Pires Cremasco, Felipe André dos Santos, Maria Cristina Rizk, et al. Sustainability Switzerland, 2023 Inadequate disposal of Municipal Solid Waste (MSW) is one of the greatest environmental issues confronted nowadays. One of the techniques used for its final disposal is incineration, otherwise known as mass burning. Although this procedure remains very controversial in Brazil, some recent studies published in Europe reveal a large amount of misinformation about it. It has been widely used in European countries, Japan, and a few U.S. cities and has been increasingly and significantly adopted in China. Therefore, this article aims to carry out a literature review on the evolution of waste-to-energy recovery from Municipal Solid Waste (MSW) worldwide and the progress of mass-burning technologies, particularly in the Brazilian context. For such a purpose, global scientific databases were selected and some of their results allowed us to present how the main WtE recovery technologies function, as well as their benefits and impacts. Moreover, it was possible to systematize the main regulatory frameworks on the theme in Brazil and to reveal the country’s electricity generation capacity, in addition to depicting the progress of Waste-to-Energy Plants (WtEPs) undergoing licensing processes in the state of São Paulo.
Meat Quality and Muscle Tissue Proteome of Crossbred Bulls Finished under Feedlot Using Wet Distiller Grains By-Product Welder Baldassini, Mohammed Gagaoua, Bismarck Santiago, Leone Rocha, Juliana Torrecilhas, et al. Foods, 2022 Wet distiller grains (WDG) are a corn by-product rich in protein and fiber that can be used in feedlot diets. This study evaluated F1 Angus-Nellore bulls fed on a control diet vs. WDG (n = 25/treatment). After a period of 129 days on these feeds, the animals were slaughtered and Longissimus thoracis samples were collected for both a meat quality evaluation and gel-based proteomic analyses. A greater ribeye area (99.47 cm²) and higher carcass weight (333.6 kg) (p < 0.05) were observed in the WDG-finished cattle compared to the control (80.7 cm²; 306.3 kg). Furthermore, there were differences (p < 0.05) in the intramuscular fat between the WDG and control animals (IMF = 2.77 vs. 4.19%), which led to a significant decrease (p < 0.05) in saturated fatty acids (FA). However, no differences (p > 0.10) were observed in terms of tenderness, evaluated using Warner–Bratzler shear force (WBSF). The proteomic and bioinformatic analyses revealed substantial changes in the biological processes, molecular functions, and cellular components of the WDG-finished cattle compared to the control. Proteins related to a myriad of interconnected pathways, such as contractile and structural pathways, energy metabolism, oxidative stress and cell redox homeostasis, and transport and signaling. In this experiment, the use of WDG supplementation influenced the protein expression of several proteins, some of which are known biomarkers of beef quality (tenderness and color), as well as the protein–protein interactions that can act as the origins of increases in muscle growth and reductions in IMF deposition. However, despite the effects on the proteome, the tenderness, evaluated by WBSF, and fatty acid profile were not compromised by WDG supplementation.
Metalloproteomic Strategies for Identifying Proteins as Biomarkers of Mercury Exposure in Serrasalmus rhombeus from the Amazon Region João Vitor de Queiroz, Bruna Cavecci-Mendonça, José Cavalcante Souza Vieira, Renata Aparecida Martins, Andrey Sávio de Almeida Assunção, et al. Biological Trace Element Research, 2021 This manuscript describes the results of a metalloproteomic study of mercury in samples of muscle and liver tissue of the species Serrasalmus rhombeus , popularly known as black piranha and characterised as the most voracious and aggressive predator in the Brazilian Amazon. The metalloproteomic study involved using two-dimensional electrophoresis (2D PAGE) to fractionate the proteome of the muscle and liver tissue samples, along with atomic absorption spectrometry in a graphite furnace (GFAAS) to identify mercury associated with protein SPOTs and mass spectrometry with electrospray ionisation (ESI-MS/MS) to characterise the mercury-binding proteins. The protein SPOTs characterised showed concentrations in the order of 156 mg kg −1 , which ranks as the highest concentrations of mercury determined so far in metalloproteomic studies involving fish species in the Amazon region. Based on FASTA sequences of proteins characterised by ESI-MS/MS, bioinformatics studies were performed that allowed identifying nine proteins with characteristics of biomarkers of mercury exposure. Of those proteins, glutathione peroxidase stands out as an enzyme of great importance in the antioxidant defence of organisms subjected to oxidative stress caused by xenobiotics.
Application of oxidative process to degrade paraquat present in the commercial herbicide Y. S. Tadayozzi, F. A. Santos, E. Vicente, J. C. Forti Journal of Environmental Science and Health Part B Pesticides Food Contaminants and Agricultural Wastes, 2021 Paraquat is resistant to degradation by conventional treatments, being necessary to use treatments with greater effectiveness, such as advanced oxidative processes. In this work, different advanced oxidative processes were applied (Fenton, electro-Fenton, photoelectro-oxidation and photoelectro-Fenton) employing oxide electrodes to degrade Gramoxone, a commercial herbicide that contains paraquat in its composition. The degradation and formation of by-products were accompanied by high performance liquid chromatography, total organic carbon (TOC) and chemical oxygen demand (COD). The results showed that the photoelectro-Fenton process was the most efficient due to the synergistic effect, reaching 79% degradation of the initial compound and 82% and 71% removal of TOC and COD, respectively. After the application of the electro-Fenton and photoelectro-Fenton oxidation processes, short-chain carboxylic acids such as succinic acid, oxalic acid, acetic acid and formic acid were identified as by-products of the oxidation of Gramoxone. The results were satisfactory and deserve to be highlighted, as a commercial formulation was used, making the scenario more realistic.
Study on Mercury Methylation in the Amazonian Rivers in Flooded Areas for Hydroelectric Use Vinicius M. Gomes, Ademir dos Santos, Luiz F. Zara, Dayana D. Ramos, Juliane C. Forti, et al. Water Air and Soil Pollution, 2019 This study aimed to estimate in laboratory the temporal production of methylmercury during the filling of reservoirs of hydropower plants and to correlate it to the ecosystem of different locations in northern Brazil: Jirau hydropower plant in the Madeira River in the state of Rondônia (white waters—under construction), Cana Brava hydropower plant in the Tocantins River in the state of Goiás (clear waters—completed), and the Negro River in the Amazon (black waters—comparative). After collecting water, soil, and sediment samples in the regions mentioned, a microcosm was created to reproduce the conditions close to those found in nature. Water/soil/Hg0/Hg2+ and water/sediment/Hg0/Hg2+ were added to glass recipients. Next, methylmercury concentration was monitored by atomic fluorescence spectrometry, total organic carbon by TOC 5000A, and physical and chemical parameters such as pH, redox potential, and dissolved oxygen, for 25 days. The results obtained allow concluding that organic matter plays an important role, providing excess methyl groups to react with inorganic Hg and form organic Hg. The Negro River, which has higher contents of organic matter in its soil, water, and sediment, presented higher potential of mercury methylation in both experiments performed, followed by rivers Madeira and Tocantins.
Zinc and lead content and availability in Brazilian soil contaminated with residue of a secondary smelting lead recycling plant Gazi University Journal of Science, 2012
Levels of copper in Nile tilapia from Brazil Renato C.F. Neves, Paula M. Moraes, Jeisson E.M. Ferrari, Paula M. Lima, Felipe A. Santos, et al. Food Additives and Contaminants Part B Surveillance, 2011
Applying Machine Learning Fraud Detection to Healthcare Payment Systems: An Adaptation Study J Rocha, M Alves, R Oliveira, F Santos 2025 Citations: 1
Reduction in Chemical Oxygen Demand of Effluents from the Confectionery Sector of Agroindustry Using the Fenton Process MAP Frigulio, AG Morales, FA Santos, JC Forti Sustainable Chemistry 6 (4), 32 , 2025 2025
First-order molecular hyperpolarizability of xanthoangelol derivatives FA Santos, HJ Mello, MS Barbosa, LMG Abegão The European Physical Journal Plus 140 (9), 904 , 2025 2025
Effects of heat stress on serum proteomics, laying performance and egg quality in aged laying hens SG Gonzalez, FP de Oliveira, AR Gomes, B Cavecci-Mendonça, ... Discover Animals 2 (1), 52 , 2025 2025 Citations: 3
Refuse-Derived Fuel with the Addition of Peanut Shells: An Evaluation Using a Decision-Making Support Algorithm N Dadario, MM Neto, FA Santos, LRAG Filho, CP Cremasco Energies 18 (10), 2429 , 2025 2025 Citations: 2
Cross-cultural adaptation and validation of the Portuguese version of the Metacognitive Prospective Memory Inventory—Short Form (MPMI-s) in non-central nervous system cancer … F Santos, A Bártolo, SM Fernandes, AF Oliveira, AP Caetano, IS Silva, ... Healthcare 13 (5), 463 , 2025 2025
Comparing Ensemble Methods for Credit Card Fraud Detection: A Performance Analysis on Multiple Datasets J Rocha, M Alves, R Oliveira, F Santos 2025 Citations: 2
Quantification of flavonoids, minerals, and pigments present in “Nanicão” bananas during the ripening process AV de Souza, VFS Favaro, JM de Mello, FA Dos Santos, GB Dall'Antonia, ... Journal of Food Science 89 (5), 2774-2786 , 2024 2024 Citations: 8
Electrochemical processes used to degrade thiamethoxam in water and toxicity analyses in non-target organisms JC Forti, PEM Robles, YS Tadayozzi, MAF Demori, FA Santos, FF Putti, ... Processes 12 (5), 887 , 2024 2024 Citations: 5
Relationship of the “Dequada” phenomenon with mercury methylation in Pantanal, Brazil GA Nunes, DD Ramos, JC Forti, DD Ramos, L Oliveira, DSS Junior, ... Water 16 (9), 1204 , 2024 2024 Citations: 1
Waste-to-energy recovery from municipal solid waste: Global scenario and prospects of mass burning technology in Brazil N Dadario, LRA Gabriel Filho, CP Cremasco, FA Santos, MC Rizk, ... Sustainability 15 (6), 5397 , 2023 2023 Citations: 39
Teste fragilidade osmótica por citometria de fluxo, o teste de referência do futuro: Estudo comparativo entre três soluções salinas M Santos, J Schelfhout, AH Santos, S Fernandes, V Ventura, L Oliveira, ... BioMed Lab , 2023 2023
Meat quality and muscle tissue proteome of crossbred bulls finished under feedlot using wet distiller grains by-product W Baldassini, M Gagaoua, B Santiago, L Rocha, J Torrecilhas, R Torres, ... Foods 11 (20), 3233 , 2022 2022 Citations: 16
Degradation of commercial glyphosate-based herbicide via advanced oxidative processes in aqueous media and phytotoxicity evaluation using maize seeds VEC da Silva, YS Tadayozzi, FF Putti, FA Santos, JC Forti Science of the Total Environment 840, 156656 , 2022 2022 Citations: 39
Formulações de biotintas à base de alginato contendo suspensão de células e esferóides, considerando parâmetros otimizados no fatiamento AP OLIVEIRA, ACD RODAS, JA DERNOWSEK, A QUEIROZ, FA SANTOS, ... 2021
Tratamento de efluentes provenientes da fabricação de lentes solares JC Forti, YS Tadayozzi, TCC da Silva, CRV de Andrade, FA dos Santos Research, Society and Development 10 (11), e108101119397-e108101119397 , 2021 2021
Application of oxidative process to degrade paraquat present in the commercial herbicide YS Tadayozzi, FA Santos, EF Vicente, JC Forti Journal of Environmental Science and Health, Part B 56 (7), 670-674 , 2021 2021 Citations: 14
Metalloproteomic Strategies for Identifying Proteins as Biomarkers of Mercury Exposure in Serrasalmus rhombeus from the Amazon Region JV de Queiroz, B Cavecci-Mendonça, JCS Vieira, RA Martins, ... Biological Trace Element Research 199 (2), 712-720 , 2021 2021 Citations: 13
Feasibility of prototyping the Jominy Test device: corroborating for studies and preliminary results of the heating and data acquisition subsystems GAS Boaventura, ROB Santos, RP Gama, RES Cabette, MFB Motta, ... Journal of Materials Science and Chemical Engineering 9, 23-38 , 2021 2021 Citations: 3
Redução de nutrientes da vinhaça por microalgas Chlorella vulgaris JC Forti, MGDB Lanza, MS Ferreira, RR de Souza, RAM Uribe, ... Research, Society and Development 9 (10), e5879108763-e5879108763 , 2020 2020 Citations: 1
MOST CITED SCHOLAR PUBLICATIONS
GFAAS determination of mercury in muscle samples of fish from Amazon, Brazil PM Moraes, FA Santos, B Cavecci, CCF Padilha, JCS Vieira, PS Roldan, ... Food chemistry 141 (3), 2614-2617 , 2013 2013 Citations: 89
Properties of Y-TZP/Al2O3 ceramic nanocomposites obtained by high-energy ball milling C Santos, MH Koizumi, J Daguano, FA Santos, CN Elias, AS Ramos Materials Science and Engineering: A 502 (1-2), 6-12 , 2009 2009 Citations: 53
Double beta decay and neutrino mass models JC Helo, M Hirsch, T Ota, FA dos Santos Journal of High Energy Physics 2015 (5), 1-40 , 2015 2015 Citations: 44
A preliminary and qualitative metallomics study of mercury in the muscle of fish from Amazonas, Brazil PM Moraes, FA Santos, CCF Padilha, JCS Vieira, LF Zara, ... Biological trace element research 150 (1), 195-199 , 2012 2012 Citations: 44
Combined OPLS-DA and decision tree as a strategy to identify antimicrobial biomarkers of volatile oils analyzed by gas chromatography-mass spectrometry FA dos Santos, IP Sousa, NAJC Furtado, FB Da Costa Revista Brasileira de Farmacognosia 28 (6), 647-653 , 2018 2018 Citations: 43
Analytical approach to the metallomic of Nile tilapia ( Oreochromis niloticus ) liver tissue by SRXRF and FAAS after 2D-PAGE separation: Preliminary results PM Lima, R de CF Neves, FA Dos Santos, CA Pérez, MOA Da Silva, ... Talanta 82 (3), 1052-1056 , 2010 2010 Citations: 43
Waste-to-energy recovery from municipal solid waste: Global scenario and prospects of mass burning technology in Brazil N Dadario, LRA Gabriel Filho, CP Cremasco, FA Santos, MC Rizk, ... Sustainability 15 (6), 5397 , 2023 2023 Citations: 39
Degradation of commercial glyphosate-based herbicide via advanced oxidative processes in aqueous media and phytotoxicity evaluation using maize seeds VEC da Silva, YS Tadayozzi, FF Putti, FA Santos, JC Forti Science of the Total Environment 840, 156656 , 2022 2022 Citations: 39
Metallomic study on plasma samples from Nile tilapia using SR-XRF and GFAAS after separation by 2D PAGE: initial results FA Santos, PM Lima, RCF Neves, PM Moraes, CA Pérez, MOA Silva, ... Microchimica Acta 173 (1), 43-49 , 2011 2011 Citations: 34
Influence of treatment with quercetin on lipid parameters and oxidative stress of pregnant diabetic rats C Pereira Braga, AC Momentti, F Barbosa Peixoto, ... Canadian Journal of Physiology and Pharmacology 91 (2), 171-177 , 2013 2013 Citations: 32
A metalloproteomics study on the association of mercury with breast milk in samples from lactating women in the Amazon region of Brazil FA Dos Santos, B Cavecci, JCS Vieira, VP Franzini, A Santos, ... Archives of environmental contamination and toxicology 69 (2), 223-229 , 2015 2015 Citations: 26
Determinação de fósforo biodisponível em rações de peixes utilizando extração assistida por ultra-som e espectrofotometria no visível PM Moraes, VR Loureiro, PM Padilha, RCF Neves, MAD Saleh, ... Química Nova 32 (4), 923-927 , 2009 2009 Citations: 22
Assessment of chromium contamination in the Monte Alegre stream: a case study JJ Corbi, FA Santos, R Zerlin, A Santos, CG Froehlich, S Trivinho-Strixino Brazilian Archives of Biology and Technology 54 (3), 613-620 , 2011 2011 Citations: 19
Sepse por Serratia marcescens KPC PF Del Peloso, MFL Barros, FA Santos Jornal Brasileiro de Patologia e Medicina Laboratorial 46 (5), 365-367 , 2010 2010 Citations: 18
Meat quality and muscle tissue proteome of crossbred bulls finished under feedlot using wet distiller grains by-product W Baldassini, M Gagaoua, B Santiago, L Rocha, J Torrecilhas, R Torres, ... Foods 11 (20), 3233 , 2022 2022 Citations: 16
Distribuição e biodisponibilidade de crômio em solos contaminados por resíduos de couro A Santos, LC Oliveira, WG Botero, AGR Mendonça, FA Santos, JC Rocha, ... Quimica Nova 32 (7), 1693-1697 , 2009 2009 Citations: 16
ECONOMIA CRIATIVA: SALVADOR NA ROTA DOS DISTRITOS CRIATIVOS/CREATIVE ECONOMY: SAVIOR ON THE ROUTE OF CREATIVE DISTRICTS FAD Santos, JC Rocha Brazilian Journal of Development 6 (11), 84803-84814 , 2020 2020 Citations: 15
Study on mercury methylation in the Amazonian rivers in flooded areas for hydroelectric use VM Gomes, A dos Santos, LF Zara, DD Ramos, JC Forti, DD Ramos, ... Water, Air, & Soil Pollution 230 (9), 211 , 2019 2019 Citations: 15
Fracionamento de cobre em proteínas do plasma, músculo e fígado de tilápia do Nilo RCF Neves, PM Lima, WA Baldassini, FA Santos, PM Moraes, GR Castro, ... Química Nova 35 (3), 493-498 , 2012 2012 Citations: 15
Relação do ganho de peso, antes e durante a gravidez, com a macrossomia fetal em gestações complicadas pelo diabetes gestacional e hiperglicemia leve Relationship of weight … CP Braga, S HIRAKAWA, ANAA HENRIQUE CEP 18610, 285 , 2011 2011 Citations: 15