Fernanda Fonseca

@inrae.fr

Paris-Saclay Food and Bioproduct Engineering research unit (UMR 782 SayFood INRAE-AgroParisTech)
INRAE - French National Research Institute for Agriculture, Food and Environment

Fernanda Fonseca


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https://researchid.co/ffonseca
Research Director (since January 2015) ), in Paris-Saclay Food and Bioproduct Engineering research unit (UMR 782 SayFood INRAE-AgroParisTech), Versailles-Grignon Centre, French National Research Institute for Agriculture, Food and Environment (INRAE), France.

Researcher Scientist (September 2001 – December 2014), in the Joint Research Unit for Food Process Engineering and Microbiology (UMR 782 GMPA INRA-AgroParisTech), Versailles-Grignon Centre, Institut National de la Recherche Agronomique (INRA), France.

EDUCATION

Habilitation à Diriger des Recherches (HDR). Université de Technologie de Compiègne, 2010. Title : « Stabilization of bio functionalities trough an approach combining the understanding of mechanisms and the product-process engineering”

Ph.D. Degree in Biotechnology and Process Engineering, Institut National Agronomique Paris-Grignon (AgroParisTech), 2001.
Ph.D. thesis title: "Influence of cryoprotection and freezing on the acidification activity of thermopile lactic acid bacteria: relationships between biological and thermodynamic

Master Degree in Biotechnology and Process Engineering, Institut National Agronomique Paris-Grignon (AgroParisTech), 1997.
M.Sc. thesis title: "Study of the freezing step on the activity of frozen lactic acid

Engineer in Chemical Engineering, Montevideo University (Uruguay), 1996.

RESEARCH INTERESTS

Main fields of expertise:
Biotechnology and process engineering: fermentation, formulation, and stabilization of bioproducts.
• Bioproducts: micro-organisms, proteins, food products.
• Stabilization processes: freezing and freeze-drying
• Biophysical characterization of bioproducts (thermal analysis, freeze-drying microscopy, Fourier Transformed InfraRed microspectroscopy)
Research approach:
Focusing on biophysical and chemical behaviours of bioproducts during stabilization processes and by relating them to biological and functional responses, to identify and quantify the mechanisms governing the degradation and preservation of bioproducts during the stabilization processes. The ambition is also to find general principles for simplifying and rationalizing the development of newly formulated products and the stabilization process optimization, with particular attention to limiting the environmental impact.
4976

Scholar Citations

37

Scholar h-index

62

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Understanding bacterial stress sensitivity and environmental impact to propose eco-friendly preservation strategies
    M Gagneten, S Passot, C Pénicaud, F Fonseca
    Cryobiology 121, 105379 , 2025
    2025
  • Freeze-dried preservation of carnobacterium maltaromaticum based on main protective mechanisms
    S Cenard, X Wood, P Lieben, S Passot, F Fonseca
    Cryobiology 121, 105449 , 2025
    2025
  • Dataset on the life cycle assessment of the production of stabilized lactic acid bacteria
    M Gagneten, C Quentier, S Passot, S Cenard, F Fonseca, C Pénicaud
    Data in Brief 60, 111541 , 2025
    2025
    Citations: 1
  • Enhanced antibacterial efficacy of biocompatible Ag-doped ZnO/AgO/TiO2 nanocomposites against multiresistant bacteria
    RO Trevisan, JM Oliveira, HF Perini, U Travaglini, TKL Rezende, ...
    Next Materials 7, 100447 , 2025
    2025
    Citations: 14
  • Use of Legume Wastewater Extracts on the Storage Stability of Freeze-Dried Lactiplantibacillus plantarum WCFS1
    GN Martins, M Guerrero Sánchez, AD Carboni, S Cenard, F Fonseca, ...
    Food and Bioprocess Technology 18 (2), 1707-1718 , 2025
    2025
    Citations: 3
  • Bench scale Layer-by-Layer microencapasulation of Lactiplantibacillus plantarum WCFS1
    N Romano, G Tavares, S Passot, MG Sanchez, M Golowczyc, S Campoy, ...
    Food Research International 200, 115431 , 2025
    2025
    Citations: 2
  • Oligosaccharides as potential protectants for preserving freeze-dried lactic acid bacteria
    S Passot, S Cenard, P Lieben, S Ghorbal, G Martins, P Castilho, ...
    Cryobiology 117, 105016 , 2024
    2024
  • Improving ligilactobacillus salivarius CECT5713 freeze-dried stability through physical and biochemical characterization
    MG Sanchez, S Passot, M Olivares, F Fonseca
    Cryobiology 117, 105095 , 2024
    2024
  • Joining environmental impacts and product quality in Life Cycle Assessment: The case of the production and storage of lactic acid bacteria concentrates
    M Gagneten, C Quentier, S Passot, S Cenard, F Fonseca, C Pénicaud
    Cleaner Environmental Systems 15, 100245 , 2024
    2024
    Citations: 2
  • Mechanistic study of the differences in lactic acid bacteria resistance to freeze-or spray-drying and storage
    M Gagneten, S Passot, S Cenard, S Ghorbal, C Schebor, F Fonseca
    Applied Microbiology and Biotechnology 108 (1), 361 , 2024
    2024
    Citations: 33
  • Scale-up of layer-by-layer microencapsulation and freeze-drying of probiotic bacteria
    N Romano, G Tavares, S Passot, F Fonseca, S Campoy, M Guerrero, ...
    Basic Protocols in Encapsulation of Food Ingredients, 57-67 , 2024
    2024
  • Mars and icy moon relevant brines and pressures depress the onset of intracellular vitrification to deep subzero temperatures
    S Gault, F Fonseca, CS Cockell
    60th Annual Meeting of the Society for Low Temperature Biology , 2024
    2024
  • Investigation of Freezing and Freeze-Drying for Preserving and Re-Using a Whole Microbial Cheese Community
    W Cao, S Passot, F Irlinger, F Fonseca
    Foods 13 (12), 1809 , 2024
    2024
    Citations: 3
  • Preservation of Bacillus subtilis ’ cellular liquid state at deep sub-zero temperatures in perchlorate brines
    S Gault, F Fonseca, CS Cockell
    Communications Biology 7 (1), 588 , 2024
    2024
    Citations: 9
  • Chickpeas’ cooking wastewater as an alternative source of galacto-oligosaccharides for improving the freeze-dried resistance of lactic acid bacteria
    S Passot, S Cenard, P Lieben, S Ghorbal, GN Martins, PC Castilho, ...
    ACS Food Science & Technology 4 (6), 1490-1500 , 2024
    2024
    Citations: 6
  • The challenge of preserving beneficial bacteria: strategies and tools to identify stress mechanisms and sites of cell damage induced by dehydration processes
    F Fonseca, S Passot
    ISLFD 2024-10Th International Symposium on Lyophilization of Pharmaceuticals , 2024
    2024
  • Stabilization of Lactiplantibacillus plantarum WCFS1 during freezing, freeze-drying, and storage using legume wastewater extracts
    GN Martins, MG Sanchez, AD Carboni, F Fonseca, S Campoy, ...
    3rd Food Chemistry Conference , 2023
    2023
  • Resistencia de L. plantarum WCFS1 frente a distintos métodos de secado: análisis de componentes celulares asociados a su degradación mediante microespectroscopía FTIR en suspensión
    M Gagneten, S Passot, C Schebor, F Fonseca
    XVIII Congreso argentino de ciencia y tecnología de alimento , 2023
    2023
  • Perchlorate salts lower the vitrification point of Bacillus subtilis to temperatures lower than those expected beneath the Martian south pole
    S Gault, CS Cockell, F Fonseca, S Passot
    EANA-European Astrobiology Network Association , 2023
    2023
  • Insights into the mechanisms of L. salivarius CECT5713 resistance to freeze-dried storage
    MG Sanchez, S Passot, S Ghorbal, S Campoy, M Olivares, F Fonseca
    Cryobiology 112, 104556 , 2023
    2023
    Citations: 18

MOST CITED SCHOLAR PUBLICATIONS

  • Freezing injury: the special case of the sperm cell
    GJ Morris, E Acton, BJ Murray, F Fonseca
    Cryobiology 64 (2), 71-80 , 2012
    2012
    Citations: 269
  • Changes in texture, cellular structure and cell wall composition in apple tissue as a result of freezing
    S Chassagne-Berces, C Poirier, MF Devaux, F Fonseca, M Lahaye, ...
    Food Research International 42 (7), 788-797 , 2009
    2009
    Citations: 254
  • Method of quantifying the loss of acidification activity of lactic acid starters during freezing and frozen storage
    F Fonseca, C Béal, G Corrieu
    Journal of Dairy Research 67 (1), 83-90 , 2000
    2000
    Citations: 223
  • Operating conditions that affect the resistance of lactic acid bacteria to freezing and frozen storage
    F Fonseca, C Béal, G Corrieu
    Cryobiology 43 (3), 189-198 , 2001
    2001
    Citations: 211
  • Resistance to freezing and frozen storage of Streptococcus thermophilus is related to membrane fatty acid composition
    C Béal, F Fonseca, G Corrieu
    Journal of Dairy Science 84 (11), 2347-2356 , 2001
    2001
    Citations: 205
  • A low temperature limit for life on Earth
    A Clarke, GJ Morris, F Fonseca, BJ Murray, E Acton, HC Price
    PLoS One 8 (6), e66207 , 2013
    2013
    Citations: 204
  • Effect of Sucrose and Maltodextrin on the Physical Properties and Survival of Air‐Dried Lactobacillus bulgaricus : An in Situ Fourier Transform Infrared Spectroscopy …
    H Oldenhof, WF Wolkers, F Fonseca, S Passot, M Marin
    Biotechnology Progress 21 (3), 885-892 , 2005
    2005
    Citations: 158
  • The high viscosity encountered during freezing in glycerol solutions: effects on cryopreservation
    GJ Morris, M Goodrich, E Acton, F Fonseca
    Cryobiology 52 (3), 323-334 , 2006
    2006
    Citations: 152
  • Freeze-drying of lactic acid bacteria
    F Fonseca, S Cenard, S Passot
    Cryopreservation and freeze-drying protocols, 477-488 , 2014
    2014
    Citations: 148
  • The impact of varying cooling and thawing rates on the quality of cryopreserved human peripheral blood T cells
    J Baboo, P Kilbride, M Delahaye, S Milne, F Fonseca, M Blanco, ...
    Scientific reports 9 (1), 3417 , 2019
    2019
    Citations: 146
  • Rapidly cooled horse spermatozoa: loss of viability is due to osmotic imbalance during thawing, not intracellular ice formation
    GJ Morris, K Faszer, JE Green, D Draper, BWW Grout, F Fonseca
    Theriogenology 68 (5), 804-812 , 2007
    2007
    Citations: 145
  • Freezing protocol effect on quality properties of fruit tissue according to the fruit, the variety and the stage of maturity
    S Chassagne-Berces, F Fonseca, M Citeau, M Marin
    LWT-Food Science and Technology 43 (9), 1441-1449 , 2010
    2010
    Citations: 142
  • Cyclopropanation of unsaturated fatty acids and membrane rigidification improve the freeze-drying resistance of Lactococcus lactis subsp. lactis TOMSC161
    H Velly, M Bouix, S Passot, C Pénicaud, H Beinsteiner, S Ghorbal, ...
    Applied microbiology and biotechnology 99 (2), 907-918 , 2015
    2015
    Citations: 131
  • Factors influencing the membrane fluidity and the impact on production of lactic acid bacteria starters
    F Fonseca, C Pénicaud, EE Tymczyszyn, A Gómez-Zavaglia, S Passot
    Applied microbiology and biotechnology 103 (17), 6867-6883 , 2019
    2019
    Citations: 128
  • Collapse Temperature of Freeze‐Dried Lactobacillus bulgaricus Suspensions and Protective Media
    F Fonseca, S Passot, O Cunin, M Marin
    Biotechnology progress 20 (1), 229-238 , 2004
    2004
    Citations: 128
  • Critical water activity and amorphous state for optimal preservation of lyophilised lactic acid bacteria
    S Passot, S Cenard, I Douania, IC Trelea, F Fonseca
    Food Chemistry 132 (4), 1699-1705 , 2012
    2012
    Citations: 115
  • Stabilization of Frozen Lactobacillus delbrueckii subsp. bulgaricus in Glycerol Suspensions: Freezing Kinetics and Storage Temperature Effects
    F Fonseca, M Marin, GJ Morris
    Applied and Environmental Microbiology 72 (10), 6474-6482 , 2006
    2006
    Citations: 112
  • Ligilactobacillus salivarius functionalities, applications, and manufacturing challenges
    M Guerrero Sanchez, S Passot, S Campoy, M Olivares, F Fonseca
    Applied microbiology and biotechnology 106 (1), 57-80 , 2022
    2022
    Citations: 111
  • A Guide for Ex Vivo Handling and Storage of Stool Samples Intended for Fecal Microbiota Transplantation
    SD Burz, AL Abraham, F Fonseca, O David, A Chapron, F Béguet-Crespel, ...
    Scientific reports 9 (1), 8897 , 2019
    2019
    Citations: 109
  • Effect of controlled ice nucleation on primary drying stage and protein recovery in vials cooled in a modified freeze-dryer
    S Passot, IC Tréléa, M Marin, M Galan, GJ Morris, F Fonseca
    2009
    Citations: 103