Antonello Giovannetti
@uniroma1.it
Scopus Publications
- Systemic Nickel Allergy Syndrome: A Critical Appraisal of an Unvalidated Diagnostic Entity
Antonello Giovannetti
Clinical and Translational Allergy, 2026
Systemic Nickel Allergy Syndrome (SNAS) remains a controversial clinical construct, characterized by persistent diagnostic uncertainty and the absence of reproducible biomarkers. Available studies are predominantly limited to small case series and uncontrolled observational reports, yielding partial and inconclusive findings. Diagnostic approaches, including oral provocation tests, frequently employ nickel exposures that far exceed typical dietary intake, raising concerns regarding physiological relevance and methodological validity. Finally, scientific inquiry into this entity has largely neglected crucial aspects such as nickel bioavailability and bioaccessibility. Against this background, particularly within the Italian clinical context, SNAS has received considerable medical and public attention despite the limited and inconsistent evidence supporting its recognition as a systemic allergic condition. Reported clinical improvements following low‐nickel diets are more plausibly explained by non‐specific dietary modifications—such as reduced intake of fermentable carbohydrates—rather than by a targeted immunological response to nickel. In conclusion, SNAS does not fulfill the criteria required for recognition as a discrete pathological entity. Rather, it represents a unvalidated diagnostic label for non‐specific symptoms shared across established functional syndromes. - A 36-year-old man, body builder presenting with unexpected severe anemia
Alessio Molfino, Ottavio Martellucci, Michele Melena, Eleonora Assanto, Antonello Giovannetti, Maurizio Muscaritoli
Internal and Emergency Medicine, 2023 - Benzodiazepine diazepam regulates cell surface β1-adrenergic receptor density in human monocytes
Paola Matarrese, Sonia Maccari, Lucrezia Gambardella, Rosa Vona, Federica Barbagallo, Vanessa Vezzi, Tonino Stati, Maria Cristina Grò, Antonello Giovannetti, Liviana Catalano, Paola Molinari, Giuseppe Marano, Caterina Ambrosio
European Journal of Pharmacology, 2023 - Urticaria and coronavirus infection: A lesson from sars-cov-2 pandemic
A. Allegra, R. Asero, A. Giovannetti, S. Isola, S. Gangemi
European Annals of Allergy and Clinical Immunology, 2021
Summary Urticaria is a condition involving both skin and mucosal tissues characterized by the presence of wheals and/or angioedema. The acute form has been related to allergic reactions to drugs or foods, interaction with chemicals, or infections. We reviewed the association of urticaria with coronavirus infections. This review was carried out by the use of two search engines for published original articles, employing two key terms correlated to urticaria and viruses: "urticaria" and one term linked to each virus. The research of the relationships between SARS-CoV-2 and urticaria produced 18 papers (including a total of 114 cases). Surprisingly, the search for cases of urticaria in patients with SARS-CoV or MERS produced no results. We tried to interpret this discrepancy and attempted to analyze the possible pathogenesis of urticaria lesions in SARS-CoV-2. - Renal resistive index in IgA nephropathy and renal scleroderma vasculopathy
Rosario Cianci, Antonietta Gigante, Domenico Bagordo, Giovanni Pintus, Antonello Giovannetti, Silvia Lai, Sandro Mazzaferro, Edoardo Rosato
Microvascular Research, 2021 - Cardiovascular risk and quality of life in autosomal dominant polycys-tic kidney disease patients on therapy with tolvaptan: A pilot study
Silvia Lai, Marco Mangiulli, Adolfo M. Perrotta, Antonietta Gigante, Ludovica Napoleoni, Elena Cipolloni, Anna P. Mitterhofer, Maria L. Gasperini, Maurizio Muscaritoli, Rosario Cianci, Antonello Giovannetti, Fabiana Falco, Daniela Mastroluca, Sandro Mazzaferro
Current Vascular Pharmacology, 2021
Introduction: Cardiovascular (CV) complications are the most frequent cause of morbidity and mortality in autosomal dominant polycystic kidney disease (ADPKD) patients. In 2017, the Italian Medicines Agency authorised tolvaptan, a vasopressin V2 receptor antagonist, for the treatment of ADPKD, based on the Tolvaptan Phase 3 Efficacy and Safety Study in ADPKD (TEMPO 3: 4), TEMPO 4: 4 and Replicating Evidence of Preserved Renal Function: An Investigation of Tolvaptan Safety and Efficacy (REPRISE) studies. Aim of the Study: The aim of the study was to assess the impact of tolvaptan on CV risk and quality of life, evaluated by nutritional, inflammatory, metabolic, instrumental parameters and psychocognitive tests on ADPKD patients. Methods and Materials: We evaluated 36 patients with ADPKD; 10 patients (7 males, mean age 42.5±7.0 years) treated with tolvaptan and 26 controls (11 males, mean age 36.7±9.1 years). They underwent, at T0, monthly, and at T1 (1 year) clinical, laboratory and instrumental evaluation, in addition to psychocognitive tests. Results: In ADPKD patients treated with tolvaptan, we found at T1, a decrease in carotid intima-- media thickness (p=0.048), epicardial adipose tissue thickness (p=0.002), C-reactive protein (p=0.026), sympathovagal balance during night (p=0.045) and increased flow-mediated dilation (p=0.023) with a reduction in depression (Hamilton and Beck tests, p=0.008 and p=0.002, respectively) compared with controls. Conclusions: These preliminary results suggest that treatment with tolvaptan could improve early atherosclerosis and endothelial dysfunction markers and improve mood in ADPKD patients (probably by acting on endothelial cell and adipocyte V2 receptors). - Role of alarmins in the pathogenesis of systemic sclerosis
Antonello Giovannetti, Elisabetta Straface, Edoardo Rosato, Marco Casciaro, Giovanni Pioggia, Sebastiano Gangemi
International Journal of Molecular Sciences, 2020
Systemic sclerosis (SSc) is a rare chronic autoimmune disease associated with significant morbidity and mortality. Two main subsets of SSc are recognized: (i) diffuse cutaneous SSc with rapidly progressive fibrosis of the skin, lungs, and other internal organs; and (ii) limited cutaneous SSc, which is dominated by vascular manifestations, with skin and organ fibrosis generally limited and slowly progressing. In spite of intense investigation, both etiology and pathogenesis of SSc are still unknown. Genetic and environmental factors, as well as abnormalities of immune functions, are strongly suggested for etiology, while microvascular abnormalities, immune system activation, and oxidative stress are suggested for the pathogenesis. Recently, it has been found that a multitude of mediators and cytokines are implicated in the fibrotic processes observed in SSc. Among these, a central role could be exerted by “alarmins”, endogenous and constitutively expressed proteins/peptides that function as an intercellular signal defense. This review describes, in a detailed manner, the role of alarmins in the pathogenesis of scleroderma. - Effects of non-invasive ventilation on renal and endothelial function in patients with respiratory failure
S. Lai, S. Mazzaferro, A. Mitterhofer, F. Tinti, A. Giovannetti, C. Casella, A. Perrotta, D. Mastroluca, A. Galani, A. Marra, A. Mazzarella, A. Oliva, C. Mastroianni, P. Palange
European Review for Medical and Pharmacological Sciences, 2020
OBJECTIVE Non-invasive positive pressure ventilation (NIV) is now an indispensable safeguard in the management of many pathologies. However, sometimes the positive end-expiratory pressure (PEEP) showed harmful effects on renal function, although effects on renal hemodynamic are unclear. We aimed at evaluating the effects of NIV on renal and endothelial function, in patients with chronic or acute respiratory failure. PATIENTS AND METHODS We performed a longitudinal, prospective, interventional study. We enrolled 17 hospitalized and non-hospitalized patients (11 males) with indication to NIV and stable hemodynamic parameters. Patients were treated with NIV and followed up at T0, at T1 (at the end of the NIV cycle) and at T2 (fifteen days after). RESULTS 17 patients (11 males) with a mean age of 71.94 ± 14.89 years were enrolled. A significant increase in flow mediated dilation (FMD) was found (p = 0.004). We showed a significant improvement, after NIV, in the values of pH (p = 0.0002), pCO2 (p = 0.0001), pO2 (p = 0.04), lactates (p = 0.04), sO2 (p = 0.02) and in the P/F Ratio (p = 0.004). We also showed a significant reduction of serum glucose (p = 0.01) and a significant increase of serum chlorine (p = 0.047), while we did not report a significant increase of creatinine (p = 0.297) or a significant change in diuresis. CONCLUSIONS In our study NIV has no significant effects on renal function in patients with respiratory failure. Probably these patients required low PEEP values, which were less harmful to lung parenchyma and not effective on systemic hemodynamic. Furthermore, NIV has improved endothelial function in the short term, likely by reducing oxidative stress, as improvements of the gas-analysis parameters showed. Therefore, NIV could help to reduce cardiovascular risk of patients improving endothelial function. - Adult patients affected by cystic fibrosis in therapy with cystic fibrosis transmembrane regulator modulators and lung transplant: Renal function, metabolic and nutritional status
Silvia Lai, Sandro Mazzaferro, Anna Paola Mitterhofer, Francesca Tinti, Enea Bonci, Antonello Giovannetti, Claudio Casella, Adolfo Marco Perrotta, Domenico Bagordo, Manuel Murciano, Alessandro Galani, Camilla Celani, Patrizia Troiani, Giuseppe Cimino, Paolo Palange
Journal of Nutrition and Metabolism, 2020
Background. Cystic fibrosis (CF) is one of the most frequent genetic diseases. The discovery and implementation of new therapies prolonged the survival of CF patients in the last years. Evaluation of long-term complications could be useful to improve the outcome of these patients. Aim of the Study. To evaluate renal function, metabolic, nutritional, and inflammatory status in CF patients on cystic fibrosis transmembrane regulator (CFTR) modulators therapy as well as lung transplant recipients (LRs) and patients on conservative therapy (control group). Materials and Methods. We performed a prospective, longitudinal study on 69 CF patients. Clinical and laboratory parameters (metabolic and nutritional indices and inflammatory markers) were evaluated in all patients before starting CFTR therapy or transplant (T0) and after 3 years (T1). Results. We enrolled 69 CF patients (42 males). Patients were distributed into three groups. The average age was 35.01 ± 10.57 years for the control group (group 0), 32.47 ± 9.40 years for patients on CFTR modulators therapy (group 1), and 38.93 ± 7.14 years for LRs (group 2). At T1, we showed a significant difference among the three groups in terms of renal function indices: creatinine, eGFR, serum nitrogen as well as serum uric acid, sodium, and potassium ( p < 0.001 , p < 0.001 , p < 0.001 , p < 0.001 , p < 0.001 , and p < 0.001 , respectively), particularly in LRs patients. Significant differences were found in nutritional status parameters among the three groups: total protein, serum albumin, serum fibrinogen, serum transferrin, and white blood cell counts ( p < 0.001 , p = 0.037 , p = 0.04 , p = 0.003 , and p = 0.007 , respectively), particularly in LRs compared with other groups. Moreover, we found significant differences in metabolic profile (HbA1c, p = 0.026 ) and inflammatory status, with a significant difference in C-reactive protein values, neutrophil counts, and neutrophil-lymphocyte ratio (NLR) among the three groups ( p < 0.001 , p = 0.005 , and p = 0.026 , respectively). Conclusions. Our study showed a reduced renal function and poor nutritional status in LRs, along with worse metabolic control. Moreover, we showed a lower inflammatory status in patients on CFTR modulators therapy. Therefore, we suggest early and careful monitoring of renal function, metabolic, and nutritional parameters in CF patients, whether they are on conservative therapy, CFTR modulators therapy, and LRs patients. - Oxidative stress in the pathogenesis of systemic scleroderma: An overview
Rosa Vona, Antonello Giovannetti, Lucrezia Gambardella, Walter Malorni, Donatella Pietraforte, Elisabetta Straface
Journal of Cellular and Molecular Medicine, 2018
Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability and death as the result of end‐stage organ failure. Two clinical subsets of the SSc are accepted: limited cutaneous SSc (lc‐SSc) and diffuse cutaneous SSc (dc‐SSc). At present, the aetiology and pathogenesis of SSc remain obscure, and consequently, disease outcome is unpredictable. Numerous studies suggest that reactive oxidizing species (ROS) play an important role in the pathogenesis of scleroderma. Over the years, several reports have supported this hypothesis for both lc‐SSc and dc‐SSc, although the specific role of oxidative stress in the pathogenesis of vascular injury and fibrosis remains to be clarified. The aim of the present review was to report and comment the recent findings regarding the involvement and role of oxidative stress in SSc pathogenesis. Biomarkers proving the link between ROS and the main pathological features of SSc have been summarized. - Lung ultrasound in systemic sclerosis: correlation with high-resolution computed tomography, pulmonary function tests and clinical variables of disease
Antonietta Gigante, Filippo Rossi Fanelli, Silvio Lucci, Giuseppe Barilaro, Silvia Quarta, Biagio Barbano, Antonello Giovannetti, Antonio Amoroso, Edoardo Rosato
Internal and Emergency Medicine, 2016 - Diesel exhaust particle exposure in vitro impacts T lymphocyte phenotype and function
Marina Pierdominici, Angela Maselli, Serena Cecchetti, Antonella Tinari, Arianna Mastrofrancesco, Michela Alfè, Valentina Gargiulo, Carlo Beatrice, Gabriele Di Blasio, Giulia Carpinelli, Elena Ortona, Antonello Giovannetti, Silvana Fiorito
Particle and Fibre Toxicology, 2014 - Relationship between redox status and cell fate in immunity and autoimmunity
Elena Ortona, Angela Maselli, Federica Delunardo, Tania Colasanti, Antonello Giovannetti, Marina Pierdominici
Antioxidants and Redox Signaling, 2014 - Autoantibodies to Estrogen Receptor α in Systemic Sclerosis (SSc) as Pathogenetic Determinants and Markers of Progression
Antonello Giovannetti, Angela Maselli, Tania Colasanti, Edoardo Rosato, Felice Salsano, Simonetta Pisarri, Ivano Mezzaroma, Walter Malorni, Elena Ortona, Marina Pierdominici
Plos One, 2013 - Skin perfusion of fingers shows a negative correlation with capillaroscopic damage in patients with systemic sclerosis
EDOARDO ROSATO, ANTONELLO GIOVANNETTI, SIMONETTA PISARRI, FELICE SALSANO
Journal of Rheumatology, 2013 - Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus
Marina Pierdominici, Marta Vomero, Cristiana Barbati, Tania Colasanti, Angela Maselli, Davide Vacirca, Antonello Giovannetti, Walter Malorni, Elena Ortona
FASEB Journal, 2012 - Autoantibodies to estrogen receptor α interfere with T lymphocyte homeostasis and are associated with disease activity in systemic lupus erythematosus
Tania Colasanti, Angela Maselli, Fabrizio Conti, Massimo Sanchez, Cristiano Alessandri, Cristiana Barbati, Davide Vacirca, Antonella Tinari, Flavia Chiarotti, Antonello Giovannetti, Flavia Franconi, Guido Valesini, Walter Malorni, Marina Pierdominici, Elena Ortona
Arthritis and Rheumatism, 2012 - Red blood cell alterations in systemic sclerosis: A pilot study
Antonello Giovannetti, Lucrezia Gambardella, Donatella Pietraforte, Edoardo Rosato, Anna Maria Giammarioli, Felice Salsano, Walter Malorni, Elisabetta Straface
Cellular Physiology and Biochemistry, 2012 - Skewed T-cell receptor variable beta repertoire and massive T-cell activation in idiopathic orofacial granulomatosis
A. Giovannetti, F. Mazzetta, A. Cavani, D. Pennino, E. Caprini, E. Ortona, G. Donato, E. Rosato, F. Salsano, M. Pierdominici
International Journal of Immunopathology and Pharmacology, 2012 - Laser Doppler perfusion imaging in systemic sclerosis impaired response to cold stimulation involves digits and hand dorsum
E. Rosato, C. Rossi, I. Molinaro, A. Giovannetti, S. Pisarri, F. Salsano
Rheumatology, 2011 - Long-term N-acetylcysteine therapy in systemic sclerosis interstitial lung disease: A retrospective study
E. Rosato, C. Rossi, I. Molinaro, A. Giovannetti, S. Pisarri, F. Salsano
International Journal of Immunopathology and Pharmacology, 2011 - Analyses of T cell phenotype and function reveal an altered T cell homeostasis in systemic sclerosis. Correlations with disease severity and phenotypes.
Antonello Giovannetti, Edoardo Rosato, Cristina Renzi, Angela Maselli, Lucrezia Gambardella, Anna Maria Giammarioli, Paolo Palange, Patrizia Paoletti, Simonetta Pisarri, Felice Salsano, Walter Malorni, Marina Pierdominici
Clinical Immunology, 2010 - Estrogen receptor profiles in human peripheral blood lymphocytes
Marina Pierdominici, Angela Maselli, Tania Colasanti, Anna Maria Giammarioli, Federica Delunardo, Davide Vacirca, Massimo Sanchez, Antonello Giovannetti, Walter Malorni, Elena Ortona
Immunology Letters, 2010 - Recurrent infections in patients with nickel allergic hypersensivity
Journal of Biological Regulators and Homeostatic Agents, 2009 - Delayed hypersensitivity to bosentan
A. Romano, A. Giovannetti, C. Caruso, E. Rosato, M. Pierdominici, F. Salsano
Allergy European Journal of Allergy and Clinical Immunology, 2009 - T-cell homeostasis: The dark(ened) side of common variable immunodeficiency
Antonello Giovannetti, Marina Pierdominici, Fernando Aiuti
Blood, 2008 - Pyrimethamine induces apoptosis of melanoma cells via a caspase and cathepsin double-edged mechanism
Anna Maria Giammarioli, Angela Maselli, Andrea Casagrande, Lucrezia Gambardella, Angelo Gallina, Massimo Spada, Antonello Giovannetti, Enrico Proietti, Walter Malorni, Marina Pierdominici
Cancer Research, 2008 - Chemokines in human immunodeficiency virus (HIV) infection
Indian Journal of Medical Research, 2008 - Progressive derangement of the t cell compartment in a case of evans syndrome
Antonello Giovannetti, Marina Pierdominici, Antonella Esposito, Maria Cagliuso, Giuseppina Stifano, Anna Maria Giammarioli, Angela Maselli, Walter Malorni, Felice Salsano, Fernando Aiuti
International Archives of Allergy and Immunology, 2008 - Apoptosis in the homeostasis of the immune system and in human immune mediated diseases
R. Paganelli, A. Giovannetti, M. Pierdominici, A. Iorio, R. Cianci, G. Murdaca, F. Puppo, F. Pandolfi
Current Pharmaceutical Design, 2008 - Unravelling the complexity of T cell abnormalities in common variable immunodeficiency
Antonello Giovannetti, Marina Pierdominici, Francesca Mazzetta, Marco Marziali, Cristina Renzi, Anna Maria Mileo, Marco De Felice, Barbara Mora, Antonella Esposito, Rossella Carello, Antonio Pizzuti, Marco G Paggi, Roberto Paganelli, Walter Malorni, Fernando Aiuti
Journal of Immunology, 2007 - Pyrimethamine (2,4-diamino-5-p-chlorophenyl-6-ethyl-pyrimidine) induces apoptosis of freshly isolated human T lymphocytes, bypassing CD95/Fas molecule but involving its intrinsic pathway
Marina Pierdominici, Anna Maria Giammarioli, Lucrezia Gambardella, Marco De Felice, Isabella Quinti, Metello Iacobini, Maurizio Carbonari, Walter Malorni, Antonello Giovannetti
Journal of Pharmacology and Experimental Therapeutics, 2005 - Impaired natural killer cell activity associates with increased susceptibility to inflammation induced by herpesvirus infection in patients with nickel hepersensitivity
F. Salsano, C. Francia, A.R. Proietti, M. Proietti, E. Roumpedaki, F. Mastronardo, M. Pierdominici, S. Pisarri, A. Giovannetti
European Journal of Inflammation, 2005 - Risk factors and occurrence of rash in HIV-positive patients not receiving nonnucleoside reverse transcriptase inhibitor: Data from a randomized study evaluating use of protease inhibitors in nucleoside-experienced patients with very low CD4 levels (<50 cells/μL)
M Floridia, R Bucciardini, V Fragola, CM Galluzzo, G Giannini, MF Pirillo, R Amici, M Andreotti, D Ricciardulli, C Tomino, S Vella, (for the ISS‐IP1 study group, listed in Appendix)
HIV Medicine, 2004 - Structured interruptions of therapy: Looking for the best protocol
Fernando Aiuti, Antonello Giovannetti
AIDS, 2003 - Persistently biased T-cell receptor repertoires in HIV-1-infected combination antiretroviral therapy-treated patients despite sustained suppression of viral replication
Antonello Giovannetti, Marina Pierdominici, Marco Marziali, Francesca Mazzetta, Elisabetta Caprini, Giandomenico Russo, Roberto Bugarini, Maria Livia Bernardi, Ivano Mezzaroma, Fernando Aiuti
Journal of Acquired Immune Deficiency Syndromes, 2003 - Biased T-cell receptor repertoires in patients with chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome)
M PIERDOMINICI, F MAZZETTA, E CAPRINI, M MARZIALI, M C DIGILIO, B MARINO, A AIUTI, F AMATI, G RUSSO, G NOVELLI, F PANDOLFI, G LUZI, A GIOVANNETTI
Clinical and Experimental Immunology, 2003 - Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia
Antonello Giovannetti, Francesca Mazzetta, Elisabetta Caprini, Alessandro Aiuti, Marco Marziali, Marina Pierdominici, Andrea Cossarizza, Luciana Chessa, Enrico Scala, Isabella Quinti, Giandomenico Russo, Massimo Fiorilli
Blood, 2002 - NK cell activity controls human herpesvirus 8 latent infection and is restored upon highly active antiretroviral therapy in AIDS patients with regressing Kaposi's sarcoma
Maria Caterina Sirianni, Laura Vincenzi, Simone Topino, Antonello Giovannetti, Francesca Mazzetta, Fabio Libi, Donato Scaramuzzi, Massimo Andreoni, Elena Pinter, Sara Baccarini, Giovanni Rezza, Paolo Monini, Barbara Ensoli
European Journal of Immunology, 2002 - Improvement of interleukin 2 production, clonogenic capability and restoration of stromal cell function in human immunodeficiency virus-type-1 patients after highly active antiretroviral therapy
Antonella Isgrò, Alessandro Aiuti, Ivano Mezzaroma, Maria Addesso, Elisabetta Riva, Antonello Giovannetti, Francesca Mazzetta, Cecilia Alario, Annamaria Mazzone, Luigi Ruco, Fernando Aiuti
British Journal of Haematology, 2002 - Changes in CCR5 and CXCR4 expression and β-chemokine production in HIV-1-infected patients treated with highly active antiretroviral therapy
Marina Pierdominici, Antonello Giovannetti, Fabrizio Ensoli, Francesca Mazzetta, Marco Marziali, Maria Rita De Cristofaro, Donatella Santini-Muratori, Wilma Leti, Fernando Aiuti
Journal of Acquired Immune Deficiency Syndromes, 2002 - European surveillance of immunoglobulin safety - Results of initial survey of 1243 patients with primary immunodeficiencies in 16 countries
Isabella Quinti, Marina Pierdominici, Marco Marziali, Antonello Giovannetti, Simona Donnanno, Helen Chapel, Janne Bjorkander, Fernando Aiuti
Clinical Immunology, 2002 - T cell receptor-Vα analysis identifies a dominant CD60+ CD26- CD49d- T cell clone in the peripheral blood of Sézary syndrome patients [4]
Enrico Scala, Maria Grazia Narducci, Paolo Amerio, Giannandrea Baliva, Romeo Simoni, Lorena Silvestri, Pietro Puddu, Ornella De Pita, Giandomenico Russo, Antonello Giovannetti
Journal of Investigative Dermatology, 2002 - T cell responses to highly active antiretroviral therapy defined by chemokine receptors expression, cytokine production, T cell receptor repertoire and anti-HIV T-lymphocyte activity
A Giovannetti, M Pierdominici, F Mazzetta, S Salemi, M Marziali, D Kuonen, F Iebba, E A Lusi, A Cossarizza, F Aiuti
Clinical and Experimental Immunology, 2001 - T-cell immune activation in children with vertically transmitted hepatitis C virus infection
Antonello Giovannetti, Francesca Mazzetta, Rossella Coviello, Anna Maria Casadei, Maria Rita Sartorerri, Marco Marziali, Marina Pierdominici, Diego Kuonen, Anna Maria Pesce, Massimo Fiorilli, Fernando Aiuti, Isabella Quinti
Viral Immunology, 2001 - T cell receptor repertoire and function in patients with DiGeorge syndrome and velocardiofacial syndrome
M Pierdominici, M Marziali, A Giovannetti, A Oliva, R Rosso, B Marino, M C Digilio, A Giannotti, G Novelli, B Dallapiccola, F Aiuti, F Pandolfi
Clinical and Experimental Immunology, 2000 - HIV type 1-induced inhibition of CD45 tyrosine phosphatase activity correlates with disease progression and apoptosis, but not with anti-CD3- induced T cell proliferation
Antonello Giovannetti, Marina Pierdominici, Francesca Mazzetta, Anna Maria Mazzone, Giovanni Ricci, Alessandra Prozzo, Franco Pandolfi, Roberto Paganelli, Fernando Aiuti
AIDS Research and Human Retroviruses, 2000 - Decreased T cell apoptosis and T cell recovery during highly active antiretroviral therapy (HAART)
Fabrizio Ensoli, Valeria Fiorelli, Cecilia Alario, Maria De Cristofaro, Donatella Santini Muratori, Arianna Novi, Maria Giovanna Cunsolo, Francesca Mazzetta, Antonello Giovannetti, Bianca Mollicone, Elena Pinter, Fernando Aiuti
Clinical Immunology, 2000 - Occurrence of Pneumocystis carinii pneumonia in HIV-1-infected patients responding to HAART: Is prophylaxis discontinuation a safe tool? [7]
Ivano Mezzaroma, Antonello Giovannetti, Elena Pinter, Fabrizio Ensoli, Fernando Aiuti
AIDS, 1999 - CCR5 and CXCR4 chemokine receptor expression and β-chemokine production during early T cell repopulation induced by highly active anti-retroviral therapy
A Giovannetti, F Ensoli, F Mazzetta, M De Cristofaro, M Pierdominici, D S Muratori, V Fiorelli, F Aiuti
Clinical and Experimental Immunology, 1999 - Apoptosis in asymptomatic HIV-1 seropositives immunized with HIV-1 env glycoprotein (gp160): Effects of administration of Zidovudine in vivo and interleukin-2 in vitro
Marina Pierdominici, Bianca Mollicone, Giovanni Ricci, Alessandra Oliva, Gianpiero D'Offizi, Antonello Giovannetti, Fernando Aiuti, Franco Pandolfi
Vaccine, 1998 - IL-10 production and CD40L expression in patients with common variable immunodeficiency
A. OLIVA, E. SCALA, I. QUINTI, R. PAGANELLI, I. J. ANSOTEGUI, A. GIOVANNETTI, M. PIERDOMINICI, F. AIUTI, F. PANDOLFI
Scandinavian Journal of Immunology, 1997 - Prolif erative responses to PHA, Anti-CD3 and antigens in patients with lymphoproliferative disease of granular lymphocytes
Antonello Giovannetti, Isabella Quinti, Luana Rainaldi, Francesca R. Maur, Alessandra Oliva, Marina Pierdominici, Giovanni Ricci, Giulio De Rossi, Antonio Cassone, Fernando Aiuti, Franco Pandolfi
Acta Haematologica, 1997 - Hepatitis C virus infection in Italian patients with hypogammaglobulinemia
Isabella Quinti, Franco Pandolfi, Roberto Paganelli, Antonello Giovannetti, Giovanna Sacco, Alessandra Oliva, Fernando Aiuti
Clinical Therapeutics, 1996 - HCV infection in a patient with hyper-IgM syndrome
Isabella Quinti, Antonello Giovannetti, Roberto Paganelli, Leopoldo Paolo Pucillo, Anna Rita Varani, Giovanni Ricci, Enrico Scala, Franco Pandolfi, Milvia Casato, Fernando Aiuti
Journal of Clinical Immunology, 1996 - Tyrosine phosphorylation pathway is involved in interferon-gamma (IFN-γ) production; effect of sodium ortho vanadate
A GIOVANNETTI, A AIUTI, P M PIZZOLI, M PIERDOMINICI, E AGOSTINI, A OLIVA, F DIANZANI, F AIUTI, F PANDOLFI
Clinical and Experimental Immunology, 1995 - HCV infection in patients with primary defects of immunoglobulin production
I Quinti, F Pandolfi, R Paganelli, D EL Salman, A Giovannetti, R Rosso, A Oliva, L Rainaldi, F Aiuti
Clinical and Experimental Immunology, 1995 - Apoptosis-related mortality in vitro of mononuclear cells from patients with HIV infection correlates with disease severity and progression
F. Pandolfi, M. Pierdominici, A. Oliva, G. D??Offizi, I. Mezzaroma, B. Mollicone, A. Giovannetti, L. Rainaldi, I. Quinti, F. Aiuti
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1995 - Immunodeficiency with hyperimmunoglobulinemia M in two female patients is not associated with abnormalities of CD40 or CD40 ligand expression
Alessandra Oliva, Isabella Quinti, Enrico Scala, Emanuele Fanales-Belasio, Luana Rainaldi, Marina Pierdominici, Antonello Giovannetti, Roberto Paganelli, Fernando Aiuti, Franco Pandolfi
Journal of Allergy and Clinical Immunology, 1995 - Abnormalities of lymphocyte subpopulations in CVI do not correlate with increased production of IL-6
Immunodeficiency, 1993 - Immunization of Macaca fascicularis with inactivated SIV preparations: challenge with human- or monkey-derived SIV and the effects of a longer immunization schedule.
F. Titti, M.L. Koanga Mogtomo, A. Borsetti, A. Geraci, L. Sernicola, G. Panzini, G.P. Turillazzi, S. Baroncelli, A. Giovannetti, R. Zamarchi, A. Amadori, F. Dianzani, L. Chieco‐Bianchi, G.B. Rossi, P. Verani
Journal of Medical Primatology, 1993 - Fibroblast-derived factors preserve viability in vitro of mononuclear cells isolated from subjects with HIV-1 infection
AIDS, 1993 - Vaccination of pregnant cynomolgus monkeys with whole formalin-inactivated SIVmac251.
F. Titti, A. Borsetti, A. Geraci, L. Sernicola, L. Giuseppini, G.P. Turillazzi, M. Pace, S. Baroncelli, A. Amadori, A. Giovannetti, F. Dianzani, L. Chieco‐Bianchi, G.B. Rossi, P. Verani
Journal of Medical Primatology, 1992 - Alterations of T-cell functions during Friend leukemia complex infection: Defective signal transduction?
ELISABETTA SOLDAINI, DONATELLA MATTEUCCI, MARIA R. CAPOBIANCHI, FULVIA BALDINOTTI, ANTONELLO GIOVANNETTI, FERDINANDO DIANZANI, MAURO BENDINELLI
Viral Immunology, 1991 - Role of interferon in lethality and lymphoid atrophy induced by coxsackievirus B3 infection of mice
MARIA R. CAPOBIANCHI, DONATELLA MATTEUCCI, ANTONELLO GIOVANNETTI, ELISABETTA SOLDAINI, MAURO BENDINELLI, JOHN G. STANTON, FERDINANDO DIANZANI
Viral Immunology, 1991
