Gopal Kumar Mahato

@cusb.ac.in

Department of Chemistry
Central University of South Bihar India

https://researchid.co/gopalkumar

RESEARCH, TEACHING, or OTHER INTERESTS

Chemistry, Organic Chemistry, General Chemistry, Agricultural and Biological Sciences

Scopus Publications

Scholar Citations

Scholar h-index

Scholar i10-index

Scopus Publications

Fluorescent fluorinated materials: A novel material for application in photodynamic therapy and designing chemical sensors
Girish Chandra, Birkishore Mahto, Vijay Raj Singh, Gopal Kumar Mahato, and Ujala Rani
Elsevier BV

Effective light-induced fluorescent H-aggregation of fluorinated pyridyl-azo dye via photoisomerization
Jitendra Modi, Samridhi Patel, Gopal Kumar Mahato, Birkishore Mahto, and Girish Chandra
Wiley
AbstractHere we present the synthesis of a new fluorinated pyridyl‐azo dye and demonstrate an effective way to convert monomer fluorinated pyridyl‐azo dye to H‐aggregated form through UV‐light induced trans‐cis‐trans photoisomerization. And upto a 12 : 88 ratio between monomer : aggregation was achieved through a small pulse of UV irradiation. The H‐aggregation shows a unique high extinction co‐efficient in UV‐visible absorbance and unexpected fluorescence emission with a remarkably large Stokes shift. The solvent DMF and fluorine substituent were found to have a critical role in aggregation. 1H, 19F NMR, and 19F‐DOSY NMR experiments were used to confirm the aggregation and also confirm the absence of π‐π stacking.

Biosynthesis and Synthetic Biology of Fluorinated Products in Plants
Girish Chandra, Gopal Kumar Mahato, and Birkishore Mahto
Springer Nature Singapore

Strategic lead compound design and development utilizing computer-aided drug discovery (CADD) to address herbicide-resistant Phalaris minor in wheat fields
Priyanka Rani, Bikash Kumar Rajak, Gopal Kumar Mahato, Ravindranath Singh Rathore, Girish Chandra, and Durg Vijay Singh
Wiley
AbstractWheat (Triticum aestivum) is a vital cereal crop and a staple food source worldwide. However, wheat grain productivity has significantly declined as a consequence of infestations by Phalaris minor. Traditional weed control methods have proven inadequate owing to the physiological similarities between P. minor and wheat during early growth stages. Consequently, farmers have turned to herbicides, targeting acetyl‐CoA carboxylase (ACCase), acetolactate synthase (ALS) and photosystem II (PSII). Isoproturon targeting PSII was introduced in mid‐1970s, to manage P. minor infestations. Despite their effectiveness, the repetitive use of these herbicides has led to the development of herbicide‐resistant P. minor biotypes, posing a significant challenge to wheat productivity. To address this issue, there is a pressing need for innovative weed management strategies and the discovery of novel herbicide molecules. The integration of computer‐aided drug discovery (CADD) techniques has emerged as a promising approach in herbicide research, that facilitates the identification of herbicide targets and enables the screening of large chemical libraries for potential herbicide‐like molecules. By employing techniques such as homology modelling, molecular docking, molecular dynamics simulation and pharmacophore modelling, CADD has become a rapid and cost‐effective medium to accelerate the herbicide discovery process significantly. This approach not only reduces the dependency on traditional experimental methods, but also enhances the precision and efficacy of herbicide development. This article underscores the critical role of bioinformatics and CADD in developing next‐generation herbicides, offering new hope for sustainable weed management and improved wheat cultivation practices. © 2024 Society of Chemical Industry.

Unusual oxidation of methylated diazo dye to 4,4′-dihydroxy-azobenzene: Mechanistic investigations and spectroscopic studies of the isolated product
Samridhi Patel, Gopal Kumar Mahato, and Girish Chandra
Elsevier BV

Fluorine-a small magic bullet atom in the drug development: perspective to FDA approved and COVID-19 recommended drugs
Girish Chandra, Durg Vijay Singh, Gopal Kumar Mahato, and Samridhi Patel
Springer Science and Business Media LLC

Green nanoparticles for photocatalytic organic synthesis
Girish Chandra, Gopal Kumar Mahato, and Samridhi Patel
Elsevier

RECENT SCHOLAR PUBLICATIONS

Fluorescent Fluorinated Materials: A Novel Material for Application in Photodynamic Therapy and Designing Chemical Sensors
G Chandra, B Mahto, VR Singh, GK Mahato, U Rani
Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 100677 2024

Strategic lead compound design and development utilizing Computer-Aided Drug Discovery (CADD) to address herbicide-resistant Phalaris minor in wheat fields
P Rani, BK Rajak, GK Mahato, RS Rathore, G Chandra, DV Singh
Pest Management Science 2024

Biosynthesis and Synthetic Biology of Fluorinated Products in Plants
G Chandra, GK Mahato, B Mahto
Biosynthesis of Natural Products in Plants: Bioengineering in Post-genomics 2024

Azobenzenes: Photoswitching and Their Chemical Sensor Application
G Chandra, U Rani, B Mahto, GK Mahato
Dye Chemistry-Exploring Colour From Nature to Lab 2024

Effective Light‐Induced Fluorescent H‐Aggregation of Fluorinated Pyridyl‐Azo Dye via Photoisomerization
J Modi, S Patel, GK Mahato, B Mahto, G Chandra
ChemPhotoChem 8 (5), e202300284 2024

An efficient process of preparation of morpholino-1,3,5-triazine derivatives with a potential for herbicidal activity
DV Singh, G Chandra, RS Rathore, GK Mahato, P Rani, BK Rajak
IN Patent App. 202,331,078,141 2024

Unusual oxidation of methylated diazo dye to 4, 4′-dihydroxy-azobenzene: Mechanistic investigations and spectroscopic studies of the isolated product
S Patel, GK Mahato, G Chandra
Dyes and Pigments 218, 111497 2023

Fluorine-a small magic bullet atom in the drug development: perspective to FDA approved and COVID-19 recommended drugs
G Chandra, DV Singh, GK Mahato, S Patel
Chemical Papers 77 (8), 4085-4106 2023

Green nanoparticles for photocatalytic organic synthesis
G Chandra, GK Mahato, S Patel
Nanoparticles in Green Organic Synthesis, 141-171 2023

MOST CITED SCHOLAR PUBLICATIONS

Fluorine-a small magic bullet atom in the drug development: perspective to FDA approved and COVID-19 recommended drugs
G Chandra, DV Singh, GK Mahato, S Patel
Chemical Papers 77 (8), 4085-4106 2023
Citations: 63

Effective Light‐Induced Fluorescent H‐Aggregation of Fluorinated Pyridyl‐Azo Dye via Photoisomerization
J Modi, S Patel, GK Mahato, B Mahto, G Chandra
ChemPhotoChem 8 (5), e202300284 2024
Citations: 2