Gopal Kumar Mahato

@cusb.ac.in

Department of Chemistry
Central University of South Bihar India

Gopal Kumar Mahato


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https://researchid.co/gopalkumar

RESEARCH, TEACHING, or OTHER INTERESTS

Chemistry, Organic Chemistry, General Chemistry, Agricultural and Biological Sciences
9

Scopus Publications

153

Scholar Citations

4

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Light- and Water-Driven Nanoarchitectonics of Amphiphilic Azobenzene Derivatives: Photoswitching and Self-Aggregation Dispersion Studies
    Gopal Kumar Mahato, Samridhi Patel, Durg Vijay Singh, Girish Chandra
    Chemphotochem, 2025
    Herein, how aggregation‐dispersion behavior of fluorinated azobenzene derivatives 5 and 6 with an amphiphilic dodecaoctane substituent is affected by UV light irradiation and water is described. The influence of fluorine substituents on their photophysical properties, photoswitching differences, and aggregation in waterin‐ground trans and excited cis‐state is studied. Their photophysical and photoswitching properties are investigated under the polar MeOH and nonpolar solvent benzene and it is found that 6 shows different behavior as compared to 5 in both solvents. Further, to check their aggregation properties in MeOH, a competing solvent water is added. It is observed that in MeOH–H2O solution (0.9‐1.5 mL), compounds show a redshift with a decrease in the absorbance, and fluorescence emission is found. Further, dynamic light scattering shows the opposite behavior, 5 initially is in the macromolecular aggregated state both in trans and cis‐states but the addition of water disperses the solution. However, 6 shows uniform micromolecular aggregated features in the trans‐state and disperses further after the addition of water. Scanning electron microscopy images of 5 and 6 suggest aggregated patterns that change the morphology when added to water. IR, 1H, and 19F NMR are done to understand the site of aggregation and intermolecular interactions.
  • Strategic lead compound design and development utilizing computer-aided drug discovery (CADD) to address herbicide-resistant Phalaris minor in wheat fields
    Priyanka Rani, Bikash Kumar Rajak, Gopal Kumar Mahato, Ravindranath Singh Rathore, Girish Chandra, Durg Vijay Singh
    Pest Management Science, 2025
    Wheat (Triticum aestivum) is a vital cereal crop and a staple food source worldwide. However, wheat grain productivity has significantly declined as a consequence of infestations by Phalaris minor. Traditional weed control methods have proven inadequate owing to the physiological similarities between P. minor and wheat during early growth stages. Consequently, farmers have turned to herbicides, targeting acetyl‐CoA carboxylase (ACCase), acetolactate synthase (ALS) and photosystem II (PSII). Isoproturon targeting PSII was introduced in mid‐1970s, to manage P. minor infestations. Despite their effectiveness, the repetitive use of these herbicides has led to the development of herbicide‐resistant P. minor biotypes, posing a significant challenge to wheat productivity. To address this issue, there is a pressing need for innovative weed management strategies and the discovery of novel herbicide molecules. The integration of computer‐aided drug discovery (CADD) techniques has emerged as a promising approach in herbicide research, that facilitates the identification of herbicide targets and enables the screening of large chemical libraries for potential herbicide‐like molecules. By employing techniques such as homology modelling, molecular docking, molecular dynamics simulation and pharmacophore modelling, CADD has become a rapid and cost‐effective medium to accelerate the herbicide discovery process significantly. This approach not only reduces the dependency on traditional experimental methods, but also enhances the precision and efficacy of herbicide development. This article underscores the critical role of bioinformatics and CADD in developing next‐generation herbicides, offering new hope for sustainable weed management and improved wheat cultivation practices. © 2024 Society of Chemical Industry.
  • Solvent-dependent C-H⋯F-C pseudo-hydrogen bonding in fluorinated azobenzene Schiff bases: studies on structural and atropisomerism features
    Samridhi Patel, Ujala Rani, Birkishore Mahto, Gopal Kumar Mahato, Raman K. Singh, Arnab Patra, Girish Chandra
    New Journal of Chemistry, 2025
    A pseudo-hydrogen bonding of the type C–F⋯H–C is observed in fluorinated azo Schiff bases under the influence of benzene solvent. This interaction was supported by NMR spectroscopy, which exhibited characteristic JH,F couplings of 2.0–2.4 Hz.
  • Fluorescent fluorinated materials: A novel material for application in photodynamic therapy and designing chemical sensors
    Girish Chandra, Birkishore Mahto, Vijay Raj Singh, Gopal Kumar Mahato, Ujala Rani
    Journal of Photochemistry and Photobiology C Photochemistry Reviews, 2024
  • Effective Light-Induced Fluorescent H-Aggregation of Fluorinated Pyridyl-Azo Dye via Photoisomerization
    Jitendra Modi, Samridhi Patel, Gopal Kumar Mahato, Birkishore Mahto, Girish Chandra
    Chemphotochem, 2024
    Here we present the synthesis of a new fluorinated pyridyl‐azo dye and demonstrate an effective way to convert monomer fluorinated pyridyl‐azo dye to H‐aggregated form through UV‐light induced trans‐cis‐trans photoisomerization. And upto a 12 : 88 ratio between monomer : aggregation was achieved through a small pulse of UV irradiation. The H‐aggregation shows a unique high extinction co‐efficient in UV‐visible absorbance and unexpected fluorescence emission with a remarkably large Stokes shift. The solvent DMF and fluorine substituent were found to have a critical role in aggregation. 1H, 19F NMR, and 19F‐DOSY NMR experiments were used to confirm the aggregation and also confirm the absence of π‐π stacking.
  • Biosynthesis and Synthetic Biology of Fluorinated Products in Plants
    Girish Chandra, Gopal Kumar Mahato, Birkishore Mahto
    Biosynthesis of Natural Products in Plants Bioengineering in Post Genomics Era, 2024
  • Unusual oxidation of methylated diazo dye to 4,4′-dihydroxy-azobenzene: Mechanistic investigations and spectroscopic studies of the isolated product
    Samridhi Patel, Gopal Kumar Mahato, Girish Chandra
    Dyes and Pigments, 2023
  • Fluorine-a small magic bullet atom in the drug development: perspective to FDA approved and COVID-19 recommended drugs
    Girish Chandra, Durg Vijay Singh, Gopal Kumar Mahato, Samridhi Patel
    Chemical Papers, 2023
  • Green nanoparticles for photocatalytic organic synthesis
    Girish Chandra, Gopal Kumar Mahato, Samridhi Patel
    Nanoparticles in Green Organic Synthesis Strategy Towards Sustainability, 2023

RECENT SCHOLAR PUBLICATIONS

  • Solvent Dependent C-H····F-C Pseudo Hydrogen Bonding in a Fluorinated Azobenzene Schiff Bases: Studies on Structural and Atropisomerism Features
    S Patel, U Rani, B MAHTO, GK Mahato, RK Singh, A Patra, G Chandra
    New Journal of Chemistry , 2025
    2025
  • Light‐and Water‐Driven Nanoarchitectonics of Amphiphilic Azobenzene Derivatives: Photoswitching and Self‐Aggregation Dispersion Studies
    GK Mahato, S Patel, D Vijay Singh, G Chandra
    ChemPhotoChem 9 (8), e202500052 , 2025
    2025
    Citations: 1
  • Fluorescent fluorinated materials: A novel material for application in photodynamic therapy and designing chemical sensors
    G Chandra, B Mahto, VR Singh, GK Mahato, U Rani
    Journal of Photochemistry and Photobiology C: Photochemistry Reviews 60, 100677 , 2024
    2024
    Citations: 11
  • Strategic lead compound design and development utilizing Computer-Aided Drug Discovery (CADD) to address herbicide-resistant Phalaris minor in wheat fields
    P Rani, BK Rajak, GK Mahato, RS Rathore, G Chandra, DV Singh
    Pest Management Science , 2024
    2024
    Citations: 7
  • Biosynthesis and Synthetic Biology of Fluorinated Products in Plants
    G Chandra, GK Mahato, B Mahto
    Biosynthesis of Natural Products in Plants: Bioengineering in Post-genomics … , 2024
    2024
  • Azobenzenes: Photoswitching and Their Chemical Sensor Application
    G Chandra, U Rani, B Mahto, GK Mahato
    Dye Chemistry-Exploring Colour From Nature to Lab , 2024
    2024
  • Effective Light‐Induced Fluorescent H‐Aggregation of Fluorinated Pyridyl‐Azo Dye via Photoisomerization
    J Modi, S Patel, GK Mahato, B Mahto, G Chandra
    ChemPhotoChem 8 (5), e202300284 , 2024
    2024
    Citations: 3
  • An efficient process of preparation of morpholino-1,3,5-triazine derivatives with a potential for herbicidal activity
    DV Singh, G Chandra, RS Rathore, GK Mahato, P Rani, BK Rajak
    IN Patent App. 202,331,078,141 , 2024
    2024
  • Unusual oxidation of methylated diazo dye to 4, 4′-dihydroxy-azobenzene: Mechanistic investigations and spectroscopic studies of the isolated product
    S Patel, GK Mahato, G Chandra
    Dyes and Pigments 218, 111497 , 2023
    2023
    Citations: 5
  • Fluorine-a small magic bullet atom in the drug development: perspective to FDA approved and COVID-19 recommended drugs
    G Chandra, DV Singh, GK Mahato, S Patel
    Chemical Papers 77 (8), 4085-4106 , 2023
    2023
    Citations: 126
  • Green nanoparticles for photocatalytic organic synthesis
    G Chandra, GK Mahato, S Patel
    Nanoparticles in Green Organic Synthesis, 141-171 , 2023
    2023

MOST CITED SCHOLAR PUBLICATIONS

  • Fluorine-a small magic bullet atom in the drug development: perspective to FDA approved and COVID-19 recommended drugs
    G Chandra, DV Singh, GK Mahato, S Patel
    Chemical Papers 77 (8), 4085-4106 , 2023
    2023
    Citations: 126
  • Fluorescent fluorinated materials: A novel material for application in photodynamic therapy and designing chemical sensors
    G Chandra, B Mahto, VR Singh, GK Mahato, U Rani
    Journal of Photochemistry and Photobiology C: Photochemistry Reviews 60, 100677 , 2024
    2024
    Citations: 11
  • Strategic lead compound design and development utilizing Computer-Aided Drug Discovery (CADD) to address herbicide-resistant Phalaris minor in wheat fields
    P Rani, BK Rajak, GK Mahato, RS Rathore, G Chandra, DV Singh
    Pest Management Science , 2024
    2024
    Citations: 7
  • Unusual oxidation of methylated diazo dye to 4, 4′-dihydroxy-azobenzene: Mechanistic investigations and spectroscopic studies of the isolated product
    S Patel, GK Mahato, G Chandra
    Dyes and Pigments 218, 111497 , 2023
    2023
    Citations: 5
  • Effective Light‐Induced Fluorescent H‐Aggregation of Fluorinated Pyridyl‐Azo Dye via Photoisomerization
    J Modi, S Patel, GK Mahato, B Mahto, G Chandra
    ChemPhotoChem 8 (5), e202300284 , 2024
    2024
    Citations: 3
  • Light‐and Water‐Driven Nanoarchitectonics of Amphiphilic Azobenzene Derivatives: Photoswitching and Self‐Aggregation Dispersion Studies
    GK Mahato, S Patel, D Vijay Singh, G Chandra
    ChemPhotoChem 9 (8), e202500052 , 2025
    2025
    Citations: 1
  • Solvent Dependent C-H····F-C Pseudo Hydrogen Bonding in a Fluorinated Azobenzene Schiff Bases: Studies on Structural and Atropisomerism Features
    S Patel, U Rani, B MAHTO, GK Mahato, RK Singh, A Patra, G Chandra
    New Journal of Chemistry , 2025
    2025
  • Biosynthesis and Synthetic Biology of Fluorinated Products in Plants
    G Chandra, GK Mahato, B Mahto
    Biosynthesis of Natural Products in Plants: Bioengineering in Post-genomics … , 2024
    2024
  • Azobenzenes: Photoswitching and Their Chemical Sensor Application
    G Chandra, U Rani, B Mahto, GK Mahato
    Dye Chemistry-Exploring Colour From Nature to Lab , 2024
    2024
  • An efficient process of preparation of morpholino-1,3,5-triazine derivatives with a potential for herbicidal activity
    DV Singh, G Chandra, RS Rathore, GK Mahato, P Rani, BK Rajak
    IN Patent App. 202,331,078,141 , 2024
    2024
  • Green nanoparticles for photocatalytic organic synthesis
    G Chandra, GK Mahato, S Patel
    Nanoparticles in Green Organic Synthesis, 141-171 , 2023
    2023