Hamza Mohamed Amin Mostafa

@iispv.cat

Faculty of Medicine and Health Sciences, Department of Biochemistry and Biotechnology, University of Rovira i Virgili
The Institute of Health Research Pere Virgili

Hamza Mohamed Amin Mostafa


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https://researchid.co/hamzamostafa
Mostafa obtained his PhD in personalized medicine and nutrimetabolomics at Faculty of Pharmacy and Food Sciences, University of Barcelona (UB), Spain in the programme: Nutrition and Food Sciences, with a competitive pre-doctoral scholarship (Ajuts De Personal Investigador Predoctoral En Formació - APIF). From May 2023 until Nov 2024, Mostafa worked as a postdoc researcher at NuMeH research group at Institute of Health Research Pere Virgili (IISPV) / University Rovira i Virgili (URV), and from Sep 2023 until August 2025 as an Assistant Professor at URV (partial time). Currently, Mostafa has been awarded the Spanish government–funded Juan de la Cierva postdoctoral fellowship for a two-year period starting in January 2026 at NuMeH research group at IISPV / URV.

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacy, Nutrition and Dietetics, Biochemistry, Genetics and Molecular Biology, Spectroscopy
22

Scopus Publications

359

Scholar Citations

13

Scholar h-index

14

Scholar i10-index

Scopus Publications

  • Vitamin E and cognitive function: A systematic review of clinical evidence
    Arwa M. Amin, Hamza Mostafa
    Nutrition Research, 2026
  • Breath metabolomics to determine the sputum inflammatory markers of asthma and COPD
    Ibrahim Baharudin, Mahmoud Dahab, Hamza Mostafa, Maria Basanta, Stephen J. Fowler
    Journal of Asthma, 2026
    OBJECTIVE: Differentiating between asthma and chronic obstructive pulmonary disease (COPD) and treating them correctly is challenging because their symptoms overlap and current diagnostic methods are inadequate. We explored the potential of integrating breath metabolomics with sputum inflammatory phenotyping to enhance the discrimination and characterization of respiratory diseases. METHODS: Exhaled breath samples were gathered from 74 participants (35 with asthma, 39 with COPD), and sputum samples were examined for eosinophil and neutrophil counts. Orthogonal partial least squares-discriminant analysis (OPLS-DA), logistic regression, and principal component analysis (PCA) were used for the identification of significant volatile organic compounds (VOCs) that discriminate between the diseases, and to determine their relationship to disease state and inflammatory classifications. RESULTS: Breath metabolomics effectively distinct asthma from COPD with 93.2% accuracy, identifying 10 important VOC biomarkers. Significantly, predicting sputum eosinophilia and neutrophilia phenotypes using established thresholds was more accurate (80.6%-90.5%, AUROC 0.67-0.91) compared to directly differentiating the diseases, where each inflammatory subtype presented its own VOC profile. Specific biomarkers, such as allyl methyl sulfide, epizonarene, and camphor, were identified as potential indicators of disease status and inflammatory subtypes. CONCLUSION: Using breath metabolomics in conjunction with sputum inflammatory phenotyping shows promise in effectively distinguishing between asthma and COPD, as well as identifying inflammatory subtypes, which can aid in creating personalized treatment strategies.
  • Association Between Dietary Polyphenol Intake and Semen Quality: Insights from the FERTINUTS Study
    Hamza Mostafa, Javier Mateu-Fabregat, Asmae Benchohra, Nil Novau-Ferré, Laura Panisello, Mònica Bulló
    Nutrients, 2025
    Background/Objectives: Low semen quality and male infertility are critical global health issues. Emerging research highlights that nutritional factors could play a significant role in determining reproductive outcomes. Understanding and optimizing these dietary influences, including the role of polyphenols, is crucial for developing targeted strategies to improve male fertility. We aimed to explore the relationship between the intake of different classes of polyphenols and semen quality indicators in a cohort of healthy young males. Methods: This is a secondary analysis involving 106 male individuals, aged 18–35 years, from the FERTINUTS trial. Dietary intake was assessed using 3-day dietary records, and semen quality parameters were analyzed. Multivariable linear regression analysis was employed to evaluate the associations between dietary polyphenol consumption and semen quality indicators. Results: Our findings revealed both positive and negative associations between polyphenol consumption and sperm morphology parameters. A higher intake of total polyphenols was associated with a lower percentage of abnormalities in sperm heads but a higher rate of abnormalities in the principal piece. Similar results were observed for lignan and flavonoid intake. Additionally, a higher intake of flavonoids was also associated with a greater percentage of normal sperm forms. In contrast, a higher dietary intake of stilbenes was associated with a higher percentage of combined abnormalities. Conclusions: Higher intake of polyphenols, particularly flavonoids and lignans, was associated with improved sperm head morphology but also with increased tail abnormalities, although no associations with motility or vitality were observed. These results suggest that specific polyphenol classes may have both beneficial and adverse effects on sperm structure, warranting consideration of compound type and dosage in dietary recommendations. Further studies are needed to determine whether these morphological changes impact fertilization outcomes and reproductive potential.
  • Metabolic Signature of Insulin Resistance and Risk of Alzheimer’s Disease
    Laia Gutierrez-Tordera, Laura Panisello, Pablo García-Gonzalez, Agustín Ruiz, José Luis Cantero, Melina Rojas-Criollo, Muhammad Mursil, Mercedes Atienza, Nil Novau-Ferré, Javier Mateu-Fabregat, Hamza Mostafa, Domènec Puig, Jaume Folch, Hatem Rashwan, Marta Marquié, Mercè Boada, Christopher Papandreou, Mònica Bulló
    Journals of Gerontology Series A Biological Sciences and Medical Sciences, 2025
    Background Substantial evidence supports the relationship between peripheral insulin resistance (IR) and the development of Alzheimer’s disease (AD)-dementia. However, the mechanisms explaining these associations are only partly understood. We aimed to identify a metabolic signature of IR associated with the progression from mild cognitive impairment (MCI) to AD-dementia. Methods This is a case-control study on 400 MCI subjects, free of type 2 diabetes, within the ACE cohort, including individuals ATN + and ATN−. After a median of 2.1 years of follow-up, 142 subjects converted to AD-dementia. IR was assessed using the homeostasis model assessment for insulin resistance (HOMA-IR). A targeted multiplatform approach profiled over 600 plasma metabolites. Elastic net penalized linear regression with 10-fold cross-validation was employed to select those metabolites associated with HOMA-IR. The prediction ability of the signature was assessed using support vector machine and performance metrics. The metabolic signature was associated with AD-dementia risk using a multivariable Cox regression model. Using counterfactual-based mediation analysis, we investigated the mediation role of the metabolic signature between HOMA-IR and AD-dementia. The metabolic pathways in which the metabolites were involved were identified using MetaboAnalyst. Results The metabolic signature comprised 18 metabolites correlated with HOMA-IR. After adjustments by confounders, the signature was associated with increased AD-dementia risk (HR = 1.234; 95% CI = 1.019–1.494; p < .05). The metabolic signature mediated 35% of the total effect of HOMA-IR on AD-dementia risk. Significant metabolic pathways were related to glycerophospholipid and tyrosine metabolism. Conclusions We have identified a blood-based metabolic signature that reflects IR and may enhance our understanding of the biological mechanisms through which IR affects AD-dementia.
  • Bile Acids and Risk of Adverse Cardiovascular Events and All-Cause Mortality in Patients with Acute Coronary Syndrome
    Javier Mateu-Fabregat, Hamza Mostafa, Raul Sanchez-Gimenez, Óscar M. Peiró, Gil Bonet, Anna Carrasquer, Georgios A. Fragkiadakis, Alfredo Bardaji, Mònica Bulló, Christopher Papandreou
    Nutrients, 2024
    The relationship between bile acids (BAs) and adverse cardiovascular events following acute coronary syndrome (ACS) have been little investigated. We aimed to examine the associations of BAs with the risk of cardiovascular events and all-cause mortality in ACS. We conducted a prospective study on 309 ACS patients who were followed for 10 years. Plasma BAs were quantified by liquid chromatography coupled to tandem mass spectrometry. Cox regression analyses with elastic net penalties were performed to associate BAs with MACE and all-cause mortality. Weighted scores were computed using the 100 iterated coefficients corresponding to each selected BA, and the associations of these scores with these adverse outcomes were assessed using multivariable Cox regression models. A panel of 10 BAs was significantly associated with the increased risk of MACE. The hazard ratio of MACE per SD increase in the estimated BA score was 1.35 (95% CI 1.12–1.63). Furthermore, four BAs were selected from the elastic net model for all-cause mortality, although their weighted score was not independently associated with mortality. Our findings indicate that primary and secondary BAs may play a significant role in the development of MACE. This insight holds potential for developing strategies to manage ACS and prevent adverse outcomes.
  • Effects of a High-Fat Diet on Insulin-Related miRNAs in Plasma and Brain Tissue in APPSwe/PS1dE9 and Wild-Type C57BL/6J Mice
    Melina Rojas-Criollo, Nil Novau-Ferré, Laia Gutierrez-Tordera, Miren Ettcheto, Jaume Folch, Christopher Papandreou, Laura Panisello, Amanda Cano, Hamza Mostafa, Javier Mateu-Fabregat, Marina Carrasco, Antoni Camins, Mònica Bulló
    Nutrients, 2024
    Insulin resistance (IR)-related miRNAs have been associated with the development and progression of Alzheimer’s disease (AD). The dietary modulation of these miRNAs could become a potential strategy to manage AD. The aim of this study was to evaluate the effect of a high-fat diet (HFD), which aggravates AD-related pathogenic processes, on serum, cortex and hippocampus IR-related miRNA expression. C57BL/6J WT and APPSwe/PS1dE9 mice were fed either an HFD or a conventional diet till 6 months of age. The mice fed with the HFD showed a significant increase in body weight and worsening glucose and insulin metabolism. miR-19a-3p was found to be up-regulated in the cortex, hippocampus and serum of APP/PS1 mice and in the serum and hippocampus of WT mice fed with the HFD. miR-34a-5p and miR-146a-5p were up-regulated in the serum of both groups of mice after consuming the HFD. Serum miR-29c-3p was overexpressed after consuming the HFD, along with hippocampal miR-338-3p and miR-125b-5p, only in WT mice. The HFD modulated the expression of peripheral and brain miRNAs related to glucose and insulin metabolism, suggesting the potential role of these miRNAs not only as therapeutic targets of AD but also as peripheral biomarkers for monitoring AD.
  • Dietary fat, telomere length and cognitive function: Unravelling the complex relations
    Hamza Mostafa, Laia Gutierrez-Tordera, Javier Mateu-Fabregat, Christopher Papandreou, Mònica Bulló
    Current Opinion in Lipidology, 2024
    Purpose of review The review aims to explore the recent evidence on the associations between different dietary fat intake and cognitive function, and to understand the role of telomere length in this relationship. Recent findings Clinical and preclinical studies included in this review suggest that dietary fat intake is associated with cognitive function and telomere length. High intake of saturated fats and trans fats, commonly found in ultra-processed foods, appears to have negative effects on cognitive function and telomere length, while other dietary fats, such as omega-3 polyunsaturated fatty acids and monounsaturated fatty acids are associated with improved cognitive performance and reduced telomere attrition. Controversial results related to omega-6 polyunsaturated fatty acids intake and its impact on cognitive function were found. Dietary fats may affect telomere length and cognition through oxidative stress, inflammation, and insulin resistance. Summary The current review illustrated the relationship between dietary fat and cognitive function by focusing on the role of telomere length as a potential intermediator. More future studies are required, however, in order to develop targeted interventions aimed at preserving cognitive well-being throughout life.
  • Dietary Glycemic Index and Load and Semen Quality: A Cross-Sectional and Prospective Analysis within the FERTINUTS Trial
    Javier Mateu-Fabregat, Christopher Papandreou, Laia Gutierrez-Tordera, Melina Rojas, Nil Novau-Ferré, Hamza Mostafa, Mònica Bulló
    World Journal of Men S Health, 2024
    PURPOSE: Infertility is a global health issue and nutrition plays a significant role in fertility outcomes. We aimed to investigate the cross-sectional and prospective associations of glycemic index (GI) and glycemic load (GL) with semen quality parameters in a cohort of healthy young men. MATERIALS AND METHODS: The study included 106 men aged 18-35 years from the FERTINUTS trial. Dietary intake was estimated through 3-day dietary records and several semen parameters were assessed. Multivariable linear regression analysis with the Least Absolute Shrinkage and Selection Operator (LASSO) approach was employed. RESULTS: The cross-sectional analysis revealed positive associations between GI and GL and total sperm count, sperm concentration, and total motility. In the prospective analysis, baseline GI was associated with increases in pH, vitality, immotile sperm or abnormal midpiece and decreases in total sperm count and motility. Conversely, GL was positively associated with changes in vitality and total sperm count. CONCLUSIONS: While these findings suggest that GI may have adverse effects on several sperm quality parameters, the results were not consistently observed in the cross-sectional analysis. However, GL was consistently associated with better sperm quality in both analyses. The impact of carbohydrate quality and quantity on fertility remains uncertain and larger prospective studies are needed.
  • Biomarkers of Berry Intake: Systematic Review Update
    Hamza Mostafa, Alex Cheok, Tomás Meroño, Cristina Andres-Lacueva, Ana Rodriguez-Mateos
    Journal of Agricultural and Food Chemistry, 2023
    Berries are rich in (poly)phenols, and these compounds may be beneficial to human health. Estimating berry consumption through self-reported questionnaires has been challenging due to compliance issues and a lack of precision. Estimation via food-derived biomarkers in biofluids was proposed as a complementary alternative. We aimed to review and update the existing evidence on biomarkers of intake for six different types of berries. A systematic literature search was performed to update a previous systematic review on PubMed, Web of Science, and Scopus from January 2020 until December 2022. Out of 42 papers, only 18 studies were eligible. A multimetabolite panel is suggested for blueberry and cranberry intake. Proposed biomarkers for blueberries include hippuric acid and malvidin glycosides. For cranberries, suggested biomarkers are glycosides of peonidin and cyanidin together with sulfate and glucuronide conjugates of phenyl-γ-valerolactone derivatives. No new metabolite candidates have been found for raspberries, strawberries, blackcurrants, and blackberries. Further studies are encouraged to validate these multimetabolite panels for improving the estimation of berry consumption.
  • Dietary Sources of Anthocyanins and Their Association with Metabolome Biomarkers and Cardiometabolic Risk Factors in an Observational Study
    Hamza Mostafa, Tomás Meroño, Antonio Miñarro, Alex Sánchez-Pla, Fabián Lanuza, Raul Zamora-Ros, Agnetha Linn Rostgaard-Hansen, Núria Estanyol-Torres, Marta Cubedo-Culleré, Anne Tjønneland, Rikard Landberg, Jytte Halkjær, Cristina Andres-Lacueva
    Nutrients, 2023
    Anthocyanins (ACNs) are (poly)phenols associated with reduced cardiometabolic risk. Associations between dietary intake, microbial metabolism, and cardiometabolic health benefits of ACNs have not been fully characterized. Our aims were to study the association between ACN intake, considering its dietary sources, and plasma metabolites, and to relate them with cardiometabolic risk factors in an observational study. A total of 1351 samples from 624 participants (55% female, mean age: 45 ± 12 years old) enrolled in the DCH-NG MAX study were studied using a targeted metabolomic analysis. Twenty-four-hour dietary recalls were used to collect dietary data at baseline, six, and twelve months. ACN content of foods was calculated using Phenol Explorer and foods were categorized into food groups. The median intake of total ACNs was 1.6mg/day. Using mixed graphical models, ACNs from different foods showed specific associations with plasma metabolome biomarkers. Combining these results with censored regression analysis, metabolites associated with ACNs intake were: salsolinol sulfate, 4-methylcatechol sulfate, linoleoyl carnitine, 3,4-dihydroxyphenylacetic acid, and one valerolactone. Salsolinol sulfate and 4-methylcatechol sulfate, both related to the intake of ACNs mainly from berries, were inversely associated with visceral adipose tissue. In conclusion, plasma metabolome biomarkers of dietary ACNs depended on the dietary source and some of them, such as salsolinol sulfate and 4-methylcatechol sulfate may link berry intake with cardiometabolic health benefits.
  • Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells, PANC-1, in a FAK- and NF-kB dependent manner: Results from the ATTACH-study a randomized, controlled, crossover trial in healthy subjects
    Hamza Mostafa, Inken Behrendt, Tomás Meroño, Raúl González-Domínguez, Mathias Fasshauer, Silvia Rudloff, Cristina Andres-Lacueva, Sabine Kuntz
    Biomedicine and Pharmacotherapy, 2023
  • Insulin resistance in Alzheimer's disease: The genetics and metabolomics links
    Arwa M. Amin, Hamza Mostafa, Hani M.J. Khojah
    Clinica Chimica Acta, 2023
  • A mixture of four dietary fibres ameliorates adiposity and improves metabolic profile and intestinal health in cafeteria-fed obese rats: an integrative multi-omics approach
    Núria Estanyol-Torres, Cristina Domenech-Coca, Raúl González-Domínguez, Antonio Miñarro, Ferran Reverter, Jose Antonio Moreno-Muñoz, Jesús Jiménez, Manel Martín-Palomas, Pol Castellano-Escuder, Hamza Mostafa, Santi García-Vallvé, Nerea Abasolo, Miguel A. Rodríguez, Helena Torrell, Josep M del Bas, Alex Sanchez-Pla, Antoni Caimari, Anna Mas-Capdevila, Cristina Andres-Lacueva, Anna Crescenti
    Journal of Nutritional Biochemistry, 2023
  • Influence of Plasma-Isolated Anthocyanins and Their Metabolites on Cancer Cell Migration (HT-29 and Caco-2) In Vitro: Results of the ATTACH Study
    Inken Behrendt, Isabella Röder, Frank Will, Hamza Mostafa, Raúl Gonzalez-Dominguez, Tomás Meroño, Cristina Andres-Lacueva, Mathias Fasshauer, Silvia Rudloff, Sabine Kuntz
    Antioxidants, 2022
  • Metabolomics profiling and pathway analysis of human plasma and urine reveal further insights into the multifactorial nature of coronary artery disease
    Arwa M. Amin, Hamza Mostafa, Nor Hayati Arif, Muhamad Ali SK Abdul Kader, Yuen Kah Hay
    Clinica Chimica Acta, 2019
  • Pharmacometabolomics analysis of plasma to phenotype clopidogrel high on treatment platelets reactivity in coronary artery disease patients
    Arwa M. Amin, Lim Sheau Chin, Chin-Hoe Teh, Hamza Mostafa, Dzul Azri Mohamed Noor, Muhamad Ali S.K. Abdul Kader, Yuen Kah Hay, Baharudin Ibrahim
    European Journal of Pharmaceutical Sciences, 2018
  • 1H NMR based pharmacometabolomics analysis of urine identifies metabolic phenotype of clopidogrel high on treatment platelets reactivity in coronary artery disease patients
    Arwa M. Amin, Lim Sheau Chin, Chin-Hoe Teh, Hamza Mostafa, Dzul Azri Mohamed Noor, Muhamad Ali SK Abdul Kader, Yuen Kah Hay, Baharudin Ibrahim
    Journal of Pharmaceutical and Biomedical Analysis, 2017
  • The effect of CYP2C19 genetic polymorphism and non-genetic factors on clopidogrel platelets inhibition in East Asian coronary artery disease patients
    Arwa M. Amin, Lim Sheau Chin, Dzul Azri Mohamed Noor, Hamza Mostafa, Muhamad Ali S.K. Abdul Kader, Yuen Kah Hay, Baharudin Ibrahim
    Thrombosis Research, 2017
  • Plasma metabolic biomarkers for discriminating individuals with alcohol use disorders from social drinkers and alcohol-naive subjects
    Hamza Mostafa, Arwa M. Amin, Chin-Hoe Teh, Vikneswaran a/l Murugaiyah, Nor Hayati Arif, Baharudin Ibrahim
    Journal of Substance Abuse Treatment, 2017
  • Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence
    Hamza Mostafa, Arwa M. Amin, Nor Hayati Arif, Vikneswaran A/L Murugaiyah, Baharudin Ibrahim
    Songklanakarin Journal of Science and Technology, 2017
  • Metabolic phenotyping of urine for discriminating alcohol-dependent from social drinkers and alcohol-naive subjects
    Hamza Mostafa, Arwa M. Amin, Chin-Hoe Teh, Vikneswaran Murugaiyah, Nor Hayati Arif, Baharudin Ibrahim
    Drug and Alcohol Dependence, 2016
  • Public knowledge and awareness of cardiovascular diseases and the expected role of community pharmacists in the prevention and management of cardiovascular diseases in Penang, Malaysia
    Azmi Sarriff, Arwa M. Amin, Hamza Mostafa
    Chiang Mai University Journal of Natural Sciences, 2014

RECENT SCHOLAR PUBLICATIONS

  • Breath metabolomics to determine the sputum inflammatory markers of asthma and COPD
    I Baharudin, M Dahab, H Mostafa, M Basanta, SJ Fowler
    Journal of Asthma, 1-11 , 2026
    2026
    Citations: 1
  • Vitamin E and cognitive function: A systematic review of clinical evidence
    AM Amin, H Mostafa
    Nutrition Research , 2025
    2025
    Citations: 1
  • Association Between Dietary Polyphenol Intake and Semen Quality: Insights from the FERTINUTS Study
    H Mostafa, J Mateu-Fabregat, A Benchohra, N Novau-Ferré, L Panisello, ...
    Nutrients 17 (17), 2785 , 2025
    2025
    Citations: 2
  • Metabolic signature of insulin resistance and risk of Alzheimer’s disease
    L Gutierrez-Tordera, L Panisello, P García-Gonzalez, A Ruiz, JL Cantero, ...
    The Journals of Gerontology, Series A: Biological Sciences and Medical … , 2025
    2025
    Citations: 8
  • Dietary glycemic index and load and semen quality: a cross-sectional and prospective analysis within the FERTINUTS trial
    J Mateu-Fabregat, C Papandreou, L Gutierrez-Tordera, M Rojas, ...
    The World Journal of Men's Health 42 (4), 881 , 2024
    2024
    Citations: 8
  • Bile acids and risk of adverse cardiovascular events and all-cause mortality in patients with acute coronary syndrome
    J Mateu-Fabregat, H Mostafa, R Sanchez-Gimenez, ÓM Peiró, G Bonet, ...
    Nutrients 16 (7), 1062 , 2024
    2024
    Citations: 8
  • Effects of a High-Fat Diet on Insulin-Related miRNAs in Plasma and Brain Tissue in APP Swe /PS1dE9 and Wild-Type C57BL/6J Mice
    M Rojas-Criollo, N Novau-Ferré, L Gutierrez-Tordera, M Ettcheto, J Folch, ...
    Nutrients 16 (7), 955 , 2024
    2024
    Citations: 5
  • Dietary fat, telomere length and cognitive function: unravelling the complex relations
    H Mostafa, L Gutierrez-Tordera, J Mateu-Fabregat, C Papandreou, ...
    Current Opinion in Lipidology 35 (1), 33-40 , 2024
    2024
    Citations: 13
  • Biomarkers of berry intake: systematic review update
    H Mostafa, A Cheok, T Meroño, C Andres-Lacueva, A Rodriguez-Mateos
    Journal of agricultural and food chemistry 71 (31), 11789-11805 , 2023
    2023
    Citations: 12
  • Anthocyanins and its microbial metabolites: from food sources to preventing cancer cells migration and improving cardiometabolic health
    HMA Mostafa
    Universitat de Barcelona , 2023
    2023
  • Dietary sources of anthocyanins and their association with metabolome biomarkers and cardiometabolic risk factors in an observational study
    H Mostafa, T Meroño, A Miñarro, A Sanchez-Pla, F Lanuza, ...
    Nutrients 15 (5), 1208 , 2023
    2023
    Citations: 14
  • Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells, PANC-1, in a FAK-and NF-kB dependent manner: Results from the ATTACH-study a …
    H Mostafa, I Behrendt, T Merono, R Gonzalez-Dominguez, M Fasshauer, ...
    Biomedicine & Pharmacotherapy 158, 114076 , 2023
    2023
    Citations: 26
  • Insulin resistance in Alzheimer’s disease: The genetics and metabolomics links
    AM Amin, H Mostafa, HMJ Khojah
    Clinica chimica acta 539, 215-236 , 2023
    2023
    Citations: 48
  • Dietary Sources of Anthocyanins and Their Association with Metabolome Biomarkers and Cardiometabolic Risk Factors in an Observational Study
    H Mostafa, T Meroño, A Miñarro, A Sánchez-Pla, F Lanuza, ...
    Nutrients 15 (5) , 2023
    2023
  • A mixture of four dietary fibres ameliorates adiposity and improves metabolic profile and intestinal health in cafeteria-fed obese rats: an integrative multi-omics approach
    N Estanyol-Torres, C Domenech-Coca, R González-Domínguez, ...
    The Journal of Nutritional Biochemistry 111, 109184 , 2023
    2023
    Citations: 8
  • Influence of Plasma-Isolated Anthocyanins and Their Metabolites on Cancer Cell Migration (HT-29 and Caco-2) In Vitro: Results of the ATTACH Study
    I Behrendt, I Röder, F Will, H Mostafa, R Gonzalez-Dominguez, T Meroño, ...
    Antioxidants 11 (7), 1341 , 2022
    2022
    Citations: 13
  • P258 Pharmacometabolomics analysis of plasma and urine to identify clopidogrel exposure metabolic biomarkers
    A Mohamed Amin Mostafa, H Mostafa, MA Sk Abdul Kader, Y Kah Hay
    European Heart Journal 41 (Supplement_1), ehz872.084 , 2020
    2020
    Citations: 2
  • Metabolomics profiling and pathway analysis of human plasma and urine reveal further insights into the multifactorial nature of coronary artery disease
    AM Amin, H Mostafa, NH Arif, MASKA Kader, YK Hay
    Clinica Chimica Acta 493 (June 2019), 112-122 , 2019
    2019
    Citations: 25
  • Pharmacometabolomics analysis of plasma to phenotype clopidogrel high on treatment platelets reactivity in coronary artery disease patients
    AM Amin, LS Chin, CH Teh, H Mostafa, DAM Noor, MASKA Kader, ...
    European Journal of Pharmaceutical Sciences 117, 351-361 , 2018
    2018
    Citations: 38
  • 1H NMR based pharmacometabolomics analysis of urine identifies metabolic phenotype of clopidogrel high on treatment platelets reactivity in coronary artery disease patients
    AM Amin, LS Chin, CH Teh, H Mostafa, DAM Noor, MASKA Kader, ...
    Journal of pharmaceutical and biomedical analysis 146, 135-146 , 2017
    2017
    Citations: 16

MOST CITED SCHOLAR PUBLICATIONS

  • Insulin resistance in Alzheimer’s disease: The genetics and metabolomics links
    AM Amin, H Mostafa, HMJ Khojah
    Clinica chimica acta 539, 215-236 , 2023
    2023
    Citations: 48
  • Pharmacometabolomics analysis of plasma to phenotype clopidogrel high on treatment platelets reactivity in coronary artery disease patients
    AM Amin, LS Chin, CH Teh, H Mostafa, DAM Noor, MASKA Kader, ...
    European Journal of Pharmaceutical Sciences 117, 351-361 , 2018
    2018
    Citations: 38
  • Plasma metabolic biomarkers for discriminating individuals with alcohol use disorders from social drinkers and alcohol-naive subjects
    H Mostafa, AM Amin, CH Teh, NH Arif, V a/l Murugaiyah, B Ibrahim
    Journal of substance abuse treatment 77 (June 2017), 1-5 , 2017
    2017
    Citations: 27
  • Plasma anthocyanins and their metabolites reduce in vitro migration of pancreatic cancer cells, PANC-1, in a FAK-and NF-kB dependent manner: Results from the ATTACH-study a …
    H Mostafa, I Behrendt, T Merono, R Gonzalez-Dominguez, M Fasshauer, ...
    Biomedicine & Pharmacotherapy 158, 114076 , 2023
    2023
    Citations: 26
  • Metabolomics profiling and pathway analysis of human plasma and urine reveal further insights into the multifactorial nature of coronary artery disease
    AM Amin, H Mostafa, NH Arif, MASKA Kader, YK Hay
    Clinica Chimica Acta 493 (June 2019), 112-122 , 2019
    2019
    Citations: 25
  • The effect of CYP2C19 genetic polymorphism and non-genetic factors on clopidogrel platelets inhibition in East Asian coronary artery disease patients
    Arwa M. Amin, Lim Sheau Chin, Dzul Azri Mohamed Noor, Hamza Mostafa, Muhamad ...
    Thrombosis Research Journal 158 (2017), 22-24 , 2017
    2017
    Citations: 22
  • Metabolic phenotyping of urine for discriminating alcohol-dependent from social drinkers and alcohol-naive subjects
    H Mostafa, AM Amin, CH Teh, V Murugaiyah, NH Arif, B Ibrahim
    Drug and alcohol dependence 169 (2016), 80-84 , 2016
    2016
    Citations: 21
  • Factors associated with the general public knowledge and awareness of cardiovascular diseases and its risk factors in Penang–Malaysia
    AM Amin, M Hamza, S Azmi
    ISOR Journal of Pharm 4 (6), 21-27 , 2014
    2014
    Citations: 20
  • 1H NMR based pharmacometabolomics analysis of urine identifies metabolic phenotype of clopidogrel high on treatment platelets reactivity in coronary artery disease patients
    AM Amin, LS Chin, CH Teh, H Mostafa, DAM Noor, MASKA Kader, ...
    Journal of pharmaceutical and biomedical analysis 146, 135-146 , 2017
    2017
    Citations: 16
  • Public Knowledge and Awareness of Cardiovascular Diseases and the Expected Role of Community Pharmacists in the Prevention and Management of Cardiovascular Diseases in Penang …
    A Sarriff, AM Amin, H Mostafa
    CMU J. Nat. Sci 13 (3), 355-370 , 2014
    2014
    Citations: 16
  • Dietary sources of anthocyanins and their association with metabolome biomarkers and cardiometabolic risk factors in an observational study
    H Mostafa, T Meroño, A Miñarro, A Sanchez-Pla, F Lanuza, ...
    Nutrients 15 (5), 1208 , 2023
    2023
    Citations: 14
  • Dietary fat, telomere length and cognitive function: unravelling the complex relations
    H Mostafa, L Gutierrez-Tordera, J Mateu-Fabregat, C Papandreou, ...
    Current Opinion in Lipidology 35 (1), 33-40 , 2024
    2024
    Citations: 13
  • Influence of Plasma-Isolated Anthocyanins and Their Metabolites on Cancer Cell Migration (HT-29 and Caco-2) In Vitro: Results of the ATTACH Study
    I Behrendt, I Röder, F Will, H Mostafa, R Gonzalez-Dominguez, T Meroño, ...
    Antioxidants 11 (7), 1341 , 2022
    2022
    Citations: 13
  • Biomarkers of berry intake: systematic review update
    H Mostafa, A Cheok, T Meroño, C Andres-Lacueva, A Rodriguez-Mateos
    Journal of agricultural and food chemistry 71 (31), 11789-11805 , 2023
    2023
    Citations: 12
  • Metabolic signature of insulin resistance and risk of Alzheimer’s disease
    L Gutierrez-Tordera, L Panisello, P García-Gonzalez, A Ruiz, JL Cantero, ...
    The Journals of Gerontology, Series A: Biological Sciences and Medical … , 2025
    2025
    Citations: 8
  • Dietary glycemic index and load and semen quality: a cross-sectional and prospective analysis within the FERTINUTS trial
    J Mateu-Fabregat, C Papandreou, L Gutierrez-Tordera, M Rojas, ...
    The World Journal of Men's Health 42 (4), 881 , 2024
    2024
    Citations: 8
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