Pharmaceutical Science, Organic Chemistry, Pharmacy, Drug Discovery
42
Scopus Publications
1032
Scholar Citations
18
Scholar h-index
35
Scholar i10-index
Scopus Publications
Amelioration of Hepatic Injury Through Oxidative Stress Management Employing Methanolic Extract of Crepe-Ginger (Cheilocostus speciosus (J. Koenig) C. Specht) Flower Mahathir Mohammad, Fahmida Tasnim Richi, Md. Arafat, Pair Ahmed Jiko, Mohammad Rashedul Haque, et al. Chemistry and Biodiversity, 2025 Cheilocostus speciosus (J. Koenig) C. Specht, commonly known as “crepe‐ginger,” is a traditional plant with edible flowers utilized in folk medicine. This study uses crepe‐ginger flowers to assess their hepatoprotective effects through the management of oxidative stress. C. speciosus flower's methanolic extract (CSF‐ME) was subjected to in vitro antioxidant effects were evaluated using 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) and 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS) and in vivo by catalase (CAT) assays which ameliorated CCl4‐induced hepatic injury evident by histopathological analysis. The chemical assay was evaluated via phytochemical screening and gas chromatography–tandem mass spectrometry (GC–MS/MS) analysis followed by in silico studies. The antioxidant assay DPPH (IC50 = 179.36 µg/mL) and ABTS (IC50 = 198.27 µg/mL) showed remarkable scavenging activity. Hepatotoxicity experiments demonstrated that CSF‐ME improved liver function by positively regulating AST, ALT, ALP, bilirubin, creatinine, LDL, CHO, TG, HDL, and catalase levels. Besides, histopathological analysis revealed normal hepatocyte integrity and microstructures after treatment. Besides, phytochemical screening revealed prospective phytochemical groups, while GC–MS/MS analysis recognized 40 compounds, resulting in auspicious outcomes employing computer‐aided studies. The findings indicated that the CSF‐ME possesses promising hepatoprotective and antioxidant prospects, which demand further extensive research to develop novel lead compounds from this natural source.
Chlorinated Chalcones, Steroids and Piperine from the Roots of Piper chaba H. Growing in Bangladesh and Their Cytotoxicity on HeLa Cell Lines Anath Chandra Roy, Md. Hasanur Rahman, Mohammad Rashedul Haque, Mohammad Sharifur Rahman, Tofail Ahmad Chowdhury, et al. Natural Product Communications, 2025 Background Piper chaba is a common plant in Bangladesh. It is enriched with many important biologically active compounds and popular for traditional healing. Method The methanol extract of the root of P. chaba was fractionated into n -hexane and ethyl acetate soluble fractions. The ethyl acetate fraction was subjected to various chromatographic techniques to isolate the pure compounds. The structures of the compounds were elucidated with the aid of UV, IR, NMR, including 1 H, 13 C, DEPT-135, COSY, HSQC, HMBC, spectroscopy, and LC-MS. The isolated compounds were subjected to cytotoxicity assay using HeLa cell lines. Result β-sitosterol ( 1a ) with trace of stigmasterol ( 1b ), piperine ( 2 ), ergosterol peroxide ( 3 ), ( E )-1-(4-chlorophenyl)-3-(4-methylphenyl)-prop-2-en-1-one ( 4 ), and ( E )-1-(4-chlorophenyl)-3-(4-methoxyphenyl)-prop-2-en-1-one ( 5 ) were purified. Conclusion To the best of our knowledge, this is the first report of isolation of the halogenated chalcone derivatives 4 and 5 from a natural source, whereas ergosterol peroxide ( 3 ) has not been reported from this plant before. Chalcones 4 and 5 showed significant cytotoxicity on HeLa cells.
Two rare flavonoid glycosides from Litsea glutinosa (Lour.) C. B. Rob.: experimental and computational approaches endorse antidiabetic potentiality Israt Jahan Bulbul, Md. Jamal Hossain, Mohammad Rashedul Haque, Muhammad Abdullah Al-Mansur, Choudhury M. Hasan, et al. BMC Complementary Medicine and Therapies, 2024 BackgroundLitsea glutinosa(Lour.) C. B. Rob. belongs to theLitseagenus and is categorized under the family ofLauraceae. The study aimed to investigate the phytoconstituents and pharmacological properties of methanol extract of leaves of Litsea glutinosa, focusing on antidiabetic activity via in vivo and in silico techniques.MethodsExtensive chromatographic and spectroscopic techniques were applied to isolate and characterize the constituents from theL. glutinosaplant species. The antidiabetic activity was studied in streptozotocin-induced diabetes mice, and the computational study of the isolated compounds was carried out by utilizing AutoDock Vina programs. In addition, the pharmacokinetic properties in terms of absorption, distribution, metabolism and excretion (ADME) and toxicological profiles of the isolated compounds were examined via in silico techniques.ResultsIn the present study, two flavonoid glycosides 4΄-O-methyl (2 ̋,4 ̋-di-E-p-coumaroyl) afzelin (1) and quercetin 3-O-(2 ̋,4 ̋-di-E-p-coumaroyl)-α-L-rhamnopyranoside (2) were isolated from the leaves of L. glutinosa and characterized by1H and13C NMR, COSY, HSQC, HMBC, and mass spectral data. Although compounds 1 and 2 have been reported twice from Machilis litseifolia and Lindera akoensis, and Machilis litseifolia and Mammea longifolia, respectively, this is the first report of this isolation from a Litsea species. Administering the methanolic extract ofL. glutinosaat doses of 300 and 500 mg/kg/day to mice with diabetes induced by streptozotocin led to a significant decrease in fasting blood glucose levels (p < 0.05) starting from the 7th day of treatment. Besides, the computational study and PASS analysis endorsed the current in vivo findings that the both isolated compounds exerted higher binding affinities to human pancreatic α-amylase and aldose reductase than the conventional drugs. The in silico ADMET analysis revealed that the both isolated compounds have a favorable pharmacokinetic and safety profile suitable for human consumption.ConclusionAccording to the current outcomes obtained from in vivo and in silico techniques, the leaf extract of L. glutinosa could be a natural remedy for treating diabetes, and the isolated phytoconstituents could be applied against various illnesses, mainly hyperglycemia. However, more investigations are required for extensive phytochemical isolation and pharmacological activities of these phytoconstituents against broader targets with exact mechanisms of action.
First-time report on compound isolation from two Colocasia species: vegetable-derived bioactive metabolites and their medicinal potential Safaet Alam, Fahmida Tasnim Richi, Nazim Uddin Emon, Abu Asad Chowdhury, Choudhury Mahmood Hasan, et al. Frontiers in Pharmacology, 2024 BackgroundColocasia affinis Schott and Colocasia gigantea Hook.f. are two commonly found vegetable species of the genus Colocasia, found mainly in the Asian region.ObjectivesThe objective of this study was to isolate bioactive phytochemicals from C. affinis and C. gigantea and elucidate their structure employing the NMR technique followed by bioactivity evaluation.MethodologyColumn chromatography was utilized to isolate phytochemicals, followed by NMR analysis for characterization. An in vivo analgesic test was performed through an acetic acid-induced writhing test, an anti-inflammatory test was performed through a formalin-induced licking test, and an antidiarrheal test was performed through a castor oil-induced diarrhea model. The in vitro antimicrobial test was executed through the disc diffusion method. Computer-aided simulation was also implemented to validate the wet laboratory results.ResultsSix compounds from C. affinis and C. gigantea were isolated and characterized from the dichloromethane (DCM)-soluble fractions of the methanolic extracts of these two species. Three of the compounds were from C. gigantea and proposed as penduletin (C1), a mixture of α-amyrin (C2a), β-amyrin (C2b), and monoglyceride of stearic acid (C3), while the remaining three compounds were from C. affinis and proposed as penduletin (C4) (which was also isolated from C. gigantea), 7,8-(3″,3″-dimethyl-pyrano)-4′-hydroxy flavonol (C5), and lastly a mixture of 7,8-(3″,3″-dimethyl-pyrano)-4′-hydroxy flavonol (C5) and 4′,7,8-trihydroxy flavonol (C6). These compounds showed promising zones of inhibition against Gram-positive and Gram-negative bacteria and fungi. In the antidiarrheal test, C5 demonstrated the highest reduction in castor oil-induced diarrhea (44.44%) at a dose of 20 mg/kg compared to loperamide’s 77.78% reduction. However, the analgesic assessment showed a noteworthy inhibition of acetic acid-induced writhing by C1/C4 and C2 (56.52%) at a dose of 20 mg/kg compared to the 76.09% by diclofenac sodium. In comparison, C2 showed pronounced anti-inflammatory action by 68.15% and 52.06% reduction, respectively, in the early and later phases compared to the ibuprofen’s outcomes of 73.54% and 74.68%. Plausible targets such as dihydrofolate reductase (DHFR) for antimicrobial, kappa opioid receptor (KOR) for antidiarrheal, and cyclooxygenase 2 (COX-2) for anti-inflammatory and analgesic activities showed a noteworthy binding affinity with isolated compounds, and ADME/T studies displayed these phytochemicals’ drug-likeness profiles.ConclusionTo the best of our knowledge, this is the first report on compound isolation from these plants, which demands further extensive research for more absolute findings.
PHYTOCHEMICAL AND IN VIVO BIOLOGICAL STUDIES OF TANAECIUM BILABIATUM (SPRAGUE) L.G. LOHMANN Mursalin Al Hasan, Md Ruhul Kuddus, Mohammad A Rashid, Mohammad Rashedul Haque Bangladesh Journal of Botany, 2023 Phytochemical analysis of Tanaecium bilabiatum leaf led to the isolation and identification of salacinin C, daturadiol and a mixture of triterpenes, α-amyrin and β-amyrin. Besides chemical analysis, the methanol extract of T. bilabiatum leaf, METBL was evaluated for analgesic, anti-diarrheal and hypoglycemic potential in mice model. For analgesic activity test by tail immersion technique, the extract significantly extended the percent elongation time of thermal nociception. METBL (400 mg/kg bw) also established the highest inhibition of formalin-induced abdominal writhing (69.39%) in mice, which was comparable with the standard aspirin (75.51%). Likewise, dose-dependent antidiarrheal activity was observed in this test. After oral administration, METBL demonstrated maximum inhibition (40.93%) of castor oil-induced diarrhea in mice. In oral glucose tolerance test, the plant extract produced significant (p < 0.05) hypoglycemic activity. Therefore, it is concluded that T. bilabiatum is a promising source of bioactive compounds with analgesic, antidiarrheal and hypoglycemic potential. Bangladesh J. Bot. 52(1): 119-127, 2023 (March)
Morphological, Spectroscopic and Thermal Analysis of Cellulose Nanocrystals Extracted from Waste Jute Fiber by Acid Hydrolysis Md. Sohel Rana, Md. Abdur Rahim, Md. Pervez Mosharraf, Md. Fazlul Karim Tipu, Jakir Ahmed Chowdhury, et al. Polymers, 2023 Natural cellulose, a sustainable bioresource, is highly abundant in nature. Cellulosic materials, particularly those that explore and employ such materials for industrial use, have recently attracted significant global attention in the field of material science because of the unique properties of cellulose. The hydroxyl groups enable the formation of intra- and inter-molecular hydrogen bonding and the arrangement of cellulose chains in a highly ordered crystalline zone, with the remaining disordered structure referred to as an amorphous region. The crystalline areas of cellulose are well-known as cellulose nanocrystals (CNCs). In the present study, we extracted CNCs from pure cellulose isolated from waste jute fibers by sulfuric acid hydrolysis, followed by characterization. Pure cellulose was isolated from jute fibers by treating with sodium hydroxide (20% w/w) and anthraquinone (0.5%) solution at 170 °C for 2 h, followed by bleaching with chlorine dioxide and hydrogen peroxide solution. CNCs were isolated from pure cellulose by treating with different concentrations (58% to 62%) of sulfuric acid at different time intervals (20 min to 45 min). The FTIR study of the CNCs reveals no peak at 1738 cm−1, which confirms the absence of hemicellulose in the samples. The CNCs obtained after 45 min of acid hydrolysis are rod-shaped, having an average length of 800 ± 100 nm and width of 55 ± 10 nm, with a high crystallinity index (90%). Zeta potential significantly increased due to the attachment of SO42− ions on the surface of CNC from −1.0 mV to about −30 mV, with the increment of the reaction time from 20 min to 45 min, which proved the higher stability of CNC suspension. Crystallinity increased from 80% to 90% when the reaction time was increased from 20 to 45 min, respectively, while a crystallite size from 2.705 to 4.56 nm was obtained with an increment of the acid concentration. Acid hydrolysis enhanced crystallinity but attenuated the temperature corresponding to major decomposition (Tmax) at 260 °C and the beginning of degradation (Ti) at 200 °C due to the attachment of SO42− ions on the surface, which decreased the thermal stability of CNC. The second degradation at 360 °C indicated the stable crystal structure of CNC. The endothermic peak at 255 °C in the DTA study provided evidence of sulfated nanocrystal decomposition and the recrystallization of cellulose I to cellulose II, the most stable structure among the other four celluloses. The proposed easy-to-reproduce method can successfully and efficiently produce CNCs from waste jute fibers in a straightforward way.
Antidiabetic Potential of Commonly Available Fruit Plants in Bangladesh: Updates on Prospective Phytochemicals and Their Reported MoAs Safaet Alam, Anik Dhar, Muhib Hasan, Fahmida Tasnim Richi, Nazim Uddin Emon, et al. Molecules, 2022 Diabetes mellitus is a life-threatening disorder affecting people of all ages and adversely disrupts their daily functions. Despite the availability of numerous synthetic-antidiabetic medications and insulin, the demand for the development of novel antidiabetic medications is increasing due to the adverse effects and growth of resistance to commercial drugs in the long-term usage. Hence, antidiabetic phytochemicals isolated from fruit plants can be a very nifty option to develop life-saving novel antidiabetic therapeutics, employing several pathways and MoAs (mechanism of actions). This review focuses on the antidiabetic potential of commonly available Bangladeshi fruits and other plant parts, such as seeds, fruit peals, leaves, and roots, along with isolated phytochemicals from these phytosources based on lab findings and mechanism of actions. Several fruits, such as orange, lemon, amla, tamarind, and others, can produce remarkable antidiabetic actions and can be dietary alternatives to antidiabetic therapies. Besides, isolated phytochemicals from these plants, such as swertisin, quercetin, rutin, naringenin, and other prospective phytochemicals, also demonstrated their candidacy for further exploration to be established as antidiabetic leads. Thus, it can be considered that fruits are one of the most valuable gifts of plants packed with a wide spectrum of bioactive phytochemicals and are widely consumed as dietary items and medicinal therapies in different civilizations and cultures. This review will provide a better understanding of diabetes management by consuming fruits and other plant parts as well as deliver innovative hints for the researchers to develop novel drugs from these plant parts and/or their phytochemicals.
Chemical and Pharmacological Profiling of Wrightia coccinea (roxb. Ex Hornem.) Sims Focusing Antioxidant, Cytotoxicity, Antidiarrheal, Hypoglycemic, and Analgesic Properties Tabassum Jannat, Md. Jamal Hossain, Ahmed M. El-Shehawi, Md. Ruhul Kuddus, Mohammad A. Rashid, et al. Molecules, 2022 The aim of the study was to conduct phytochemical and pharmacological investigations of Wrightia coccinea (Roxb. ex Hornem.) Sims via several in vitro, in vivo, and in silico models. A total of four compounds were identified and isolated from the methanol extract of the bark and the methanol extract of the seed pulp of W. coccinea through successive chromatographic techniques and were characterized as 3β-acetyloxy-olean-12-en-28-ol (1), wrightiadione (2), 22β-hydroxylupeol (3), and β-sitosterol (4) by spectroscopic analysis. The aqueous fraction of the bark and chloroform fraction of the fruits provided the most potent antioxidant capacity (IC50 = 7.22 and 4.5 µg/mL, respectively) in DPPH free radical scavenging assay compared with the standard ascorbic acid (IC50 = 17.45 µg/mL). The methanol bark extract and the methanol fruit coat extract exerted anti-diarrheal activity by inhibiting 74.55 ± 0.67% and 77.78 ± 1.5% (mean ± SEM) of the diarrheal episode in mice, respectively, after four hours of loading the samples. In the hypoglycemic test, the methanol bark extract and the methanol fruit coat extract (400 mg/kg) produced a significant (p < 0.05) reduction in the blood glucose level in mice. Both doses of the plant extracts (200 mg/kg and 400 mg/kg) used in the study induced a significant (p < 0.05) increase in pain reaction time. The in vitro and in vivo findings were supported by the computational studies. The isolated compounds exhibited higher binding affinity compared with the standard drugs towards the active binding sites of glutathione reductase, epidermal growth factor receptor (EGFR), kappa opioid receptor, glucose transporter 3 (GLUT 3), Mu opioid receptor, and cyclooxygenase 2 (COX-2) proteins due to their potent antioxidant, cytotoxic, anti-diarrheal, hypoglycemic, and central and peripheral analgesic properties, respectively. The current findings concluded that W. coccinea might be a potential natural source for managing oxidative stress, diarrhea, hyperglycemia, and pain. Further studies are warranted for extensively phytochemical screening and establishing exact mechanisms of action.
Phytochemical and biological investigations of methanol extract of leaves of Ziziphus mauritiana Lam Boletin Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromaticas, 2015
A new diarylheptanoid from Garuga pinnata Roxb Kulsum Ara, Mohammad R Haque, Mahammad A Kaisar, AHMM Rahman, Choudhury M Hasan, et al. Dhaka University Journal of Pharmaceutical Sciences, 2012
Pharmacological Spectrum of Boerhavia repens Fractions: In Vitro and In Vivo Insights into Antioxidant, Anti-Inflammatory, Analgesic, CNS Depressant and Non-Cytotoxic Potentials J Zaman, F Tasneem, MR Haque Bangladesh Pharmaceutical Journal 29 (1), 81-92 , 2026 2026
Amelioration of Hepatic Injury Through Oxidative Stress Management Employing Methanolic Extract of Crepe‐Ginger ( Cheilocostus speciosus (J. Koenig) C … M Mohammad, FT Richi, M Arafat, PA Jiko, MR Haque, MH Hossain, ... Chemistry & Biodiversity 22 (8), e202500261 , 2025 2025 Citations: 2
A Multifaceted Exploration of Shirakiopsis indica (Willd) Fruit: Insights into the Neuropharmacological, Antipyretic, Thrombolytic, and Anthelmintic Attributes of a … M Mohammad, MJI Mamun, MM Khatun, MH Rasel, MAA Masum, ... Drugs and Drug Candidates 4 (3), 31 , 2025 2025 Citations: 24
Phytochemical and Pharmacological Evaluation of Parmentiera aculeata (Family: Bignoniaceae) N Mahjabin, S Ashrafi, N Sharmin, MA Rashid, MR Haque Dhaka University Journal of Pharmaceutical Sciences 24 (1), 77-86 , 2025 2025
First-time report on compound isolation from two Colocasia species: vegetable-derived bioactive metabolites and their medicinal potential (vol 15, 1474706, 2024) S Alam, FT Richi, NU Emon, AA Chowdhury, CM Hasan, MR Haque FRONTIERS IN PHARMACOLOGY 16 , 2025 2025
Chlorinated Chalcones, Steroids and Piperine from the Roots of Piper chaba H. Growing in Bangladesh and Their Cytotoxicity on HeLa Cell Lines AC Roy, MH Rahman, MR Haque, MS Rahman, TA Chowdhury, ... Natural Product Communications 20 (4), 1934578X251334718 , 2025 2025
First-time report on compound isolation from two Colocasia species: vegetable-derived bioactive metabolites and their medicinal potential S Alam, FT Richi, NU Emon, AA Chowdhury, CM Hasan, MR Haque Frontiers in Pharmacology 15, 1474706 , 2024 2024 Citations: 7
Isolation and Characterization of Polyprenols from Litsea monopetala (Roxb.) Pers. MS Kamal, S Ashrafi, S Sultana, MA Rashid, M Ahsan, MM Masud, ... Dhaka University Journal of Pharmaceutical Sciences 23 (1), 63-68 , 2024 2024
Two rare flavonoid glycosides from Litsea glutinosa (Lour.) C. B. Rob.: experimental and computational approaches endorse antidiabetic potentiality IJ Bulbul, MJ Hossain, MR Haque, MA Al-Mansur, CM Hasan, A Al Hasan, ... BMC Complementary Medicine and Therapies 24 (1), 69 , 2024 2024 Citations: 10
Isolation and characterization of alkaline proteases producing indigenous Bacillus sp. as a source of thrombolytic and fibrinolytic agents T Akhtar, MAA Sikder, T Yeasmin, MA Al Mamun, MM Hoq, MM Rahman, ... Dhaka University Journal of Pharmaceutical Sciences 22 (2), 125-135 , 2023 2023 Citations: 2
Chemico-pharmacological and computational studies of Ophiorrhiza fasciculata D. Don and Psychotria silhetensis Hook. f. focusing cytotoxic, thrombolytic, anti-inflammatory … PT Rashid, MJ Hossain, MS Zahan, CM Hasan, MA Rashid, ... Heliyon 9 (9) , 2023 2023 Citations: 20
Analgesic Activity of Methanolic Extract of Litsea deccanensis Gamble Bark in Mice Model IJ Bulbul, MR Haque, MA Rashid Bangladesh Pharmaceutical Journal 26 (2), 144-149 , 2023 2023 Citations: 1
Phytochemical and in vivo biological studies of Tanaecium bilabiatum (Sprague) LG Lohmann M Al Hasan, MR Kuddus, MA Rashid, MR Haque Bangladesh Journal of Botany 52 (1), 119-127 , 2023 2023 Citations: 2
Morphological, spectroscopic and thermal analysis of cellulose nanocrystals extracted from waste jute fiber by acid hydrolysis MS Rana, MA Rahim, MP Mosharraf, MFK Tipu, JA Chowdhury, ... Polymers 15 (6), 1530 , 2023 2023 Citations: 77
In vitro screening of Litsea monopetala (Roxb.) Pers.(Lauraceae) extract: potential antioxidant, cytotoxic, thrombolytic, and anti-inflammatory properties SM Kamal, S Ashrafi, S Sultana, MR Haque J. Bio. Exp. Pharm 1, 25-38 , 2023 2023
Modification of Bulk Density, Flow Property and Crystallinity of Microcrystalline Cellulose Prepared from Waste Cotton. Materials 2023, 16 (16) S Tasnim, MFK Tipu, MS Rana, MA Rahim, M Haque, MS Amran, ... 2023 Citations: 2
Antidiabetic potential of commonly available fruit plants in Bangladesh: updates on prospective phytochemicals and their reported MoAs S Alam, A Dhar, M Hasan, FT Richi, NU Emon, MA Aziz, AA Mamun, ... Molecules 27 (24), 8709 , 2022 2022 Citations: 48
Chemical and Pharmacological Profiling of Wrightia coccinea (roxb. Ex Hornem.) Sims Focusing Antioxidant, Cytotoxic, Antidiarrheal, Hypoglycemic, and Analgesic … T Jannat, MJ Hossain, AM El-Shehawi, MR Kuddus, MA Rashid, ... Molecules 27 (13), 4024 , 2022 2022 Citations: 40
Preparation of Microcrystalline Cellulose from Dissolving Cellulose Obtained from Jute Fibers and Its Application in the Formulation of Fexofenadine Hydrochloride Tablet Dosage … AA Chowdhury, MR Haque, MS Rana, MS Amran Journal of Applied Pharmaceutical Sciences and Research 5 (4), 28-32 , 2022 2022 Citations: 2
Antidiarrheal activity of four different species of Litsea available in Bangladesh IJ Bulbul, ME Uddin, N Nahar, MR Kuddus, MR Haque Biomedical and Pharmacology Journal 14 (3), 1259-1266 , 2021 2021 Citations: 9
MOST CITED SCHOLAR PUBLICATIONS
Antidiarrheal, antimicrobial and antioxidant potentials of methanol extract of Colocasia gigantea Hook. f. leaves: evidenced from in vivo and in vitro studies along … S Alam, MA Rashid, MMR Sarker, NU Emon, M Arman, IN Mohamed, ... BMC Complementary Medicine and Therapies 21 (1), 119 , 2021 2021 Citations: 78
Morphological, spectroscopic and thermal analysis of cellulose nanocrystals extracted from waste jute fiber by acid hydrolysis MS Rana, MA Rahim, MP Mosharraf, MFK Tipu, JA Chowdhury, ... Polymers 15 (6), 1530 , 2023 2023 Citations: 77
Cytotoxic dimeric quinolone–terpene alkaloids from the root bark of Zanthoxylum rhetsa M Ahsan, MR Haque, MB Hossain, SN Islam, AI Gray, CM Hasan Phytochemistry 103, 8-12 , 2014 2014 Citations: 50
Antidiabetic potential of commonly available fruit plants in Bangladesh: updates on prospective phytochemicals and their reported MoAs S Alam, A Dhar, M Hasan, FT Richi, NU Emon, MA Aziz, AA Mamun, ... Molecules 27 (24), 8709 , 2022 2022 Citations: 48
Chemical and biological studies of Kalanchoe pinnata (Lam.) growing in Bangladesh SM Sharker, MK Hossain, MR Haque, AA Chowdhury, A Kaisar, ... Asian Pacific Journal of Tropical Biomedicine 2 (3), S1317-S1322 , 2012 2012 Citations: 42
Chemical and Pharmacological Profiling of Wrightia coccinea (roxb. Ex Hornem.) Sims Focusing Antioxidant, Cytotoxic, Antidiarrheal, Hypoglycemic, and Analgesic … T Jannat, MJ Hossain, AM El-Shehawi, MR Kuddus, MA Rashid, ... Molecules 27 (13), 4024 , 2022 2022 Citations: 40
In vitro and in vivo evaluation of pharmacological potentials of Campsis radicans L M Islam, T Jannat, MR Kuddus, MA Rashid, MR Haque Clinical Phytoscience 5 (1), 42 , 2019 2019 Citations: 39
Stereochenols A and B, two quinones from Stereospermum chelonoides MR Haque, KM Rahman, MN Iskander, CM Hasan, MA Rashid Phytochemistry 67 (24), 2663-2665 , 2006 2006 Citations: 39
In vitro antibacterial, cytotoxic and antioxidant activities of plant Nephelium longan FA Ripa, M Haque, IJ Bulbul Pakistan Journal of Biological Sciences 13 (1), 22 , 2010 2010 Citations: 38
A novel small-molecule inhibitor of IL-6 signalling G Zinzalla, MR Haque, BP Basu, J Anderson, SL Kaye, S Haider, F Hasan, ... Bioorganic & medicinal chemistry letters 20 (23), 7029-7032 , 2010 2010 Citations: 30
A Multifaceted Exploration of Shirakiopsis indica (Willd) Fruit: Insights into the Neuropharmacological, Antipyretic, Thrombolytic, and Anthelmintic Attributes of a … M Mohammad, MJI Mamun, MM Khatun, MH Rasel, MAA Masum, ... Drugs and Drug Candidates 4 (3), 31 , 2025 2025 Citations: 24
In Vitro Antioxidant and Thrombolytic Activities of Bridelia Species Growing in Bangladesh A Anjum, MA Sikder, MR Haque, CM Hasan, MA Rashid Journal of Scientific Research 5 (2), 343-351 , 2013 2013 Citations: 23
Facile oxidation of electron-poor benzo [b] thiophenes to the corresponding sulfones with an aqueous solution of H 2 O 2 and P 2 O 5 D Antonow, T Marrafa, I Dawood, T Ahmed, MR Haque, DE Thurston, ... Chemical communications 46 (13), 2289-2291 , 2010 2010 Citations: 23
New labdane diterpenes from the aerial parts of Scoparia dulcis L. M Ahsan, MR Haque, SKN Islam, AI Gray, CM Hasan Phytochemistry Letters 5 (3), 609-612 , 2012 2012 Citations: 21
Chemico-pharmacological and computational studies of Ophiorrhiza fasciculata D. Don and Psychotria silhetensis Hook. f. focusing cytotoxic, thrombolytic, anti-inflammatory … PT Rashid, MJ Hossain, MS Zahan, CM Hasan, MA Rashid, ... Heliyon 9 (9) , 2023 2023 Citations: 20
Crispene A, B, C and D, four new clerodane type furanoid diterpenes from Tinospora crispa (L.) F Hossen, R Ahasan, MR Haque, B Begum, CM Hasan Pharmacognosy Magazine 12 (Suppl 1), S37 , 2016 2016 Citations: 20
Secondary metabolites from Sterespermum chelonoides M Haque, K Rahman, B Begum, C Hasan, M Rashid Dhaka University Journal of Pharmaceutical Sciences 4 (1), 12-16 , 2005 2005 Citations: 19
Screening of ten medicinal plants of Bangladesh for analgesic activity on Swiss-albino mice MAA Sikder, RB Rashid, F Islam, A Hossian, AB Siddique, S Kabir, ... Oriental Pharmacy and Experimental Medicine 13 (4), 327-332 , 2013 2013 Citations: 18
In vitro antibacterial, antifungal and cytotoxic activity of three Bangladeshi Bridelia species A Anjum, MR Haque, MS Rahman, CM Hasan, ME Haque, MA Rashid Int. Res. Pharm. Pharmacol 1, 149-154 , 2011 2011 Citations: 18
Phytochemical investigation of schleichera oleosa (lour.) oken leaf N Anjum, MJ Hossain, MR Haque, A Chowdhury, MA Rashid, MR Kuddus Bangladesh Pharmaceutical Journal 24 (1), 33-36 , 2021 2021 Citations: 17
