Hamid Reza Moradi
@shirazu.ac.ir
Basic Sciences, School of Veterinary
Shiraz University
RESEARCH INTERESTS
Neurosciences; Veterinary Medicine; Reproductive Health
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Abbas Abdollahi, Narges Fereydouni, Hamid Moradi, Abolfazl Karimivaselabadi, Elham Zarenezhad, and Mahmoud Osanloo
Springer Science and Business Media LLC
AbstractHerbal components are highly useful assets for the advancement of novel antibacterial drugs. Nanotechnology holds great promise as an approach to enhance the effectiveness and develop the composition of these substances. The study developed nanogels incorporating camphor, thymol, and a combination derived from the initial nanoemulsions with particle sizes of 103, 85, and 135 nm, respectively. The viscosity of nanogels and the successful loading of compounds in them were examined by viscometery and ATR-FTIR studies. The bactericidal properties of the nanogels were examined against four bacterial strains. The nanogel containing camphor and thymol at 1250 µg/mL concentration exhibited complete growth suppression against Pseudomonas aeruginosa and Staphylococcus aureus. The thymol nanogel at 1250 µg/mL and the camphor nanogel at 2500 µg/mL exhibited complete inhibition of growth on Listeria monocytogenes and Escherichia coli, respectively. Both nanogels showed favorable effectiveness as antibacterial agents and could potentially examine a wide range of pathogens and in vivo studies.
Eilnaz Basardeh, Somayeh Piri-Gavgani, Hamid Reza Moradi, Masoumeh Azizi, Parastoo Mirzabeigi, Farzaneh Nazari, Mostafa Ghanei, Fereidoun Mahboudi, and Fatemeh Rahimi-Jamnani
Springer Science and Business Media LLC
Abstract Background The emergence of carbapenem-resistant and extensively drug-resistant (XDR) Acinetobacter baumannii as well as inadequate effective antibiotics calls for an urgent effort to find new antibacterial agents. The therapeutic efficacy of two human scFvs, EB211 and EB279, showing growth inhibitory activity against A. baumannii in vitro, was investigated in immunocompromised mice with A. baumannii pneumonia. Results The data revealed that infected mice treated with EB211, EB279, and a combination of the two scFvs showed better survival, reduced bacterial load in the lungs, and no marked pathological abnormalities in the kidneys, liver, and lungs when compared to the control groups receiving normal saline or an irrelevant scFv. Conclusions The results from this study suggest that the scFvs with direct growth inhibitory activity could offer promising results in the treatment of pneumonia caused by XDR A. baumannii.
Azim Ziyaei Halimehjani, Sahar Bayat, Seyyed Emad Hooshmand, Gholamhossein Tondro, Hamid Reza Moradi, and Jafar Jalaei
Elsevier BV
Milad Karamifar, Samad Sabbaghi, Mohammad Sina Mohtaram, Kamal Rasouli, Mahdi Mohsenzadeh, Hesam Kamyab, Abdollah Derakhshandeh, Leila Dolatshah, Hamidreza Moradi, and Shreeshivadasan Chelliapan
Elsevier BV
Hamidreza Moradi, Amirreza Talaiekhozani, Hesam Kamyab, Shreeshivadasan Chelliapan, and Ashok Kumar Nadda
Springer Science and Business Media LLC
Younes Kamali, Reyhaneh Almasi, Hamid Reza Moradi, and Saeid Fathollahi
Springer Science and Business Media LLC
Abstract Background The aim of the current study was to investigate the frequency of variations of the extensor tendons of the carpus and digits in the domestic dog (Canis lupus familiaris) with a reexamination of their insertions as well as the morphometric measurements of the tendons and the brachioradialis muscle. In total, we investigated 68 paired thoracic limbs of the domestic dog (16 females and 18 males) which were fixed in a 10% formalin solution. Results The extensor carpi radialis (ECR) tendons showed striking variations in both splitting and insertion sites. In 4.4% of dissections, ECR had three tendons. Of these tendons, the extra tendon either attached independently on the fourth metacarpal bone (one right) or joined its counterpart tendon at the distal end (cross-connections) (one bilateral). It is worth mentioning that one of the ECR tendons split into two or three slips which inserted on the first, second, third, or fourth metacarpal bone in 11 (16.2%) of the specimens. In addition, we found a long tendinous slip originating from the ECR tendons to digit II or III in 7.4% of the distal limbs. The most common type of contribution to digit III was a third tendon of the extensor digiti I et II (ED III) joining the extensor digitorum lateralis (EDL III) with a frequency of 17.6%. In other types of variations, the contribution to digit III was incomplete. A part of the abductor pollicis longus (APL) deep to the superficial part of the flexor retinaculum seemed to continue up to the flexor digitorum superficialis (FDS) tendon. Conclusions The rare intraspecific variations of the extensor tendons of the manus described in the current research are valuable from both clinical and phylogenetic perspectives. Nonetheless, their functional importance needs more studies.
Fariba Noori, Mahmoud Osanloo, Hamid Reza Moradi, Hamidreza Ghaderi Jafarbeigloo, Mozhgan Jirehnezhadyan, Seyed Amin Kouhpayeh, Mahtab Tirgare, Azam Bozorgi, and Arash Goodarzi
SAGE Publications
Developing wound dressings with a high potential to cover damaged skin tissue and facilitate cell adhesion and migration at the injury site is crucial in skin tissue engineering to accelerate wound healing. Electrospun nanofibers from natural/synthetic polymers are amongst the favorable wound dressings with appropriate physicochemical and biological properties. As well, nanoformulations of phenolic phytochemical “eugenol” have been shown to fasten wound healing via various anti-inflammatory and anti-oxidant effects. Herein, we developed a bi-component wound dressing of PCL/Cs electrospun nanofibers and eugenol nanogel to investigate its effects on tissue healing in vivo. PCL/Cs nanofibers were fabricated using an electrospinning method at the 15:1 ratio, and eugenol-loaded nanogels were synthesized by adding carboxymethylcellulose as the gelling agent, and their physicochemical characteristics were assessed. Scaffolds were implanted in a full-thickness excision wound model in Wistar rats, followed up for 21 days. The results showed that electrospun nanofibers had an average diameter of 228 nm with uniform and smooth morphology aligned randomly. Eugenol-loaded nanogel showed an average size distribution of 126 nm. Eugenol-loaded nanogel and nanogel + nanofiber groups significantly reduced wound surface area over 21 days. Histological evaluations showed that Eugenol-loaded nanogel and nanogel + nanofiber groups developed the full-thickness epidermis with the complete epithelium and stratum corneum, angiogenesis, and low macrophage infiltration in which predominantly mature collagen fibers were poorly and well organized, respectively. The combination of eugenol-loaded nanogel + PCL/Cs nanofiber accelerated wound healing by reducing inflammation, and edema along with enhancing angiogenesis, collagen synthesis, and re-epithelialization.
Kamal Rasouli, Jamal Rasouli, Mohammad Sina Mohtaram, Samad Sabbaghi, Hesam Kamyab, Hamidreza Moradi, and Shreeshivadasan Chelliapan
Elsevier BV
Hamidreza Moradi, Samad Sabbaghi, Naghmeh Sadat Mirbagheri, Pu Chen, Kamal Rasouli, Hesam Kamyab, and Shreeshivadasan Chelliapan
Elsevier BV
Shahrbanoo Keshavarz Azizi Raftar, Fatemeh Ashrafian, Sara Abdollahiyan, Abbas Yadegar, Hamid Reza Moradi, Morteza Masoumi, Farzam Vaziri, Arfa Moshiri, Seyed Davar Siadat, and Mohammad Reza Zali
Springer Science and Business Media LLC
AbstractInflammation plays a critical role in the promotion of hepatocyte damage and liver fibrosis. In recent years the protective role of Akkermansia muciniphila, a next-generation beneficial microbe, has been suggested for metabolic and inflammatory disorders. In this study, we aimed to evaluate the effects of live and pasteurized A. muciniphila and its extra cellular vesicles (EVs) on inflammatory markers involved in liver fibrosis in a mouse model of a high-fat diet (HFD)/carbon tetrachloride (CCl4)-induced liver injury. Firstly, the responses of hepatic stellate cells (HSCs) to live and pasteurized A. muciniphila and its EVs were examined in the quiescent and LPS-activated LX-2 cells. Next, the anti-inflammatory effects of different forms of A. muciniphila were examined in the mouse model of HFD/CCl4-induced liver injury. The gene expression of various inflammatory markers was evaluated in liver, colon, and white adipose tissues. The cytokine secretion in the liver and white adipose tissues was also measured by ELISA. The results showed that administration of live and pasteurized A. muciniphila and its EVs leads to amelioration in HSCs activation. Based on data obtained from the histopathological analysis, an improvement in gut health was observed through enhancing the epithelium and mucosal layer thickness and strengthening the intestinal integrity in all treatments. Moreover, live A. muciniphila and its EVs had inhibitory effects on liver inflammation and hepatocytes damage. In addition, the tissue cytokine production and inflammatory gene expression levels revealed that live A. muciniphila and its EVs had more pronounced anti-inflammatory effects on liver and adipose tissues. Furthermore, EVs had better effects on the modulation of gene expression related to TLRs, PPARs, and immune response in the liver. In conclusion, the present results showed that oral administration of A. muciniphila and its derivatives for four weeks could enhance the intestinal integrity and anti-inflammatory responses of the colon, adipose, and liver tissues and subsequently prevent liver injury in HFD/CCL4 mice.
Fatemeh Ashrafian, Shahrbanoo Keshavarz Azizi Raftar, Arezou Lari, Arefeh Shahryari, Sara Abdollahiyan, Hamid Reza Moradi, Morteza Masoumi, Mehdi Davari, Shohreh khatami, Mir Davood Omrani,et al.
Springer Science and Business Media LLC
Abstract Background Several studies have shown that probiotics have beneficial effects on weight control and metabolic health. In addition to probiotics, recent studies have investigated the effects of paraprobiotics and postbiotics. Therefore, we evaluated the preventive effects of live and pasteurized Akkermansia muciniphila MucT (A. muciniphila) and its extracellular vesicles (EVs) on HFD-induced obesity. Results The results showed that body weight, metabolic tissues weight, food consumption, and plasma metabolic parameters were increased in the HFD group, whereas A. muciniphila preventive treatments inhibited these HFD. The effects of pasteurized A. muciniphila and its extracellular vesicles were more noticeable than its active form. The HFD led to an increase in the colonic, adipose tissue, and liver inflammations and increased the expression of genes involved in lipid metabolism and homeostasis. Nevertheless, these effects were inhibited in mice that were administered A. muciniphila and its EVs. The assessment of the gut microbiota revealed significant differences in the microbiota composition after feeding with HFD. However, all treatments restored the alterations in some bacterial genera and closely resemble the control group. Also, the correlation analysis indicated that some gut microbiota might be associated with obesity-related indices. Conclusions Pasteurized A. muciniphila and its EVs, as paraprobiotic and postbiotic agents, were found to play a key role in the regulation of metabolic functions to prevent obesity, probably by affecting the gut-adipose-liver axis. Graphical Abstract
Fatemeh Ashrafian, Shahrbanoo Keshavarz Azizi Raftar, Arefeh Shahryari, Ava Behrouzi, Rezvan Yaghoubfar, Arezou Lari, Hamid Reza Moradi, Shohreh Khatami, Mir Davood Omrani, Farzam Vaziri,et al.
Springer Science and Business Media LLC
AbstractRecently, Akkermansia muciniphila an anaerobic member of the gut microbiota, has been proposed as a next-generation probiotic. The aim of this study was evaluation of the effect of alive and pasteurized A. muciniphila on health status, intestinal integrity, immune response, lipid metabolism, and gut microbial composition in normal-diet fed mice as well as direct effects of the bacterium on Caco-2 cell line. A total of 30 mice were distributed into three different groups, control, alive, and pasteurized A. muciniphila-treated group. After acclimation, control and treatment groups were administrated with PBS and 109 CFU/200µL of bacterial suspension for 5 weeks, respectively. Besides, Caco-2 separately exposed to alive, pasteurized A. muciniphila and PBS for 24 h. The results showed that administration of A. muciniphila leads to reduction in body, liver, and white adipose weight. Histology data revealed both treatments had no adverse effects in colon, liver, and adipose tissues as well as induced better gut structure. Moreover, biochemical parameters and inflammatory biomarkers in plasma demonstrated that pasteurized A. muciniphila had more pronounce effect. Furthermore, alive A. muciniphia had better effects on the modulation of gene expression related to fatty acid synthesis, energy homeostasis, and immune response in the liver; meanwhile, these effects in the adipose was more in the pasteurized A. muciniphila administration. More importantly, the improvement of gut health by enhancing strengthen intestinal integrity and maintaining immune homeostasis was seen in both treatments; notably, pasteurized A. muciniphila had more effective. Similarly, treatment with the pasteurized form more effectively upregulated tight junction and regulated immune response-related genes in Caco-2 cell line. Both treatments triggered the improvement of microbiota communities, particularly the alive form. Therefore, both forms of A. muciniphila could modulate lipid and immune homeostasis, improved some gut microbiota, and promoted the overall health, while all these effects were dominantly observed in pasteurized form. In conclusion, pasteurized A. muciniphila can be considered as new medical supplement to maintain health state and prevent diseases in normal mice through different mechanisms.
Shahrbanoo Keshavarz Azizi Raftar, Fatemeh Ashrafian, Abbas Yadegar, Arezou Lari, Hamid Reza Moradi, Arefeh Shahriary, Masoumeh Azimirad, Helia Alavifard, Zhaleh Mohsenifar, Mehdi Davari,et al.
American Society for Microbiology
Akkermansia muciniphila , as a member of the gut microbiota, has been proposed as a next-generation probiotic. Liver fibrosis is the main determinant of liver dysfunction and mortality in patients with chronic liver disease.
H. Moradi, Vahid Hajali, Z. Khaksar, F. Vafaee, F. Forouzanfar and S. S. Negah
Among different pathological mechanisms, neuronal loss and neurogenesis impairment in the hippocampus play important roles in cognitive decline in Alzheimer's disease (AD). AD is a progressive and complex neurodegenerative diseases, which is very debilitating. The purpose of this paper is to review recent research into neurogenesis and AD and discuss how pharmacological drugs and herbal active components have impacts on neurogenesis and consequently improve cognitive functions. To date, despite huge research, no effective treatment has been approved for AD. Therefore, an avenue for future research and drug discovery is stimulating adult hippocampal neurogenesis (AHN). Evidence suggests that neurogenesis is regulated by the pharmacological treatment that may be recommended as a part of prophylaxis and therapeutic options for AD. However, the underlying mechanisms of regulating neurogenesis in AD are not well understood. To this point, we highlight to achieve an efficient treatment in AD by manipulating neurogenesis, it's necessary to target all steps of neurogenesis.
Behrokh Marzban Abbasabadi, Hamid Reza Moradi, Shirin Arefi, and Michal Kyllar
Wiley
The Indian crested porcupine (Hystrix indica) (ICP) is widely distributed in Asia; however, compared with other rodents, little is known about the structures of its respiratory system. The aim of this study was to evaluate the histomorphology of the lower respiratory portion of the ICP to provide a basis for the identification of the normal structure of this organ. The larynx, trachea and lungs of four carcasses of adult Indian crested porcupines (two males and two females) were dissected and fixed in 10% neutral-buffered formalin. The gross anatomy and histology of all specimens were evaluated. A macroscopic evaluation showed unique structures in the ICP respiratory system, including the presence of a chamber-like structure at the origin of the bronchi and a difference in epiglottis shape between males and females. Histologically, the stratified squamous epithelium covered the epiglottis and arytenoid cartilage, and the pseudostratified ciliated columnar epithelium covered the internal part of the thyroid and cricoid cartilages. Histomorphological studies showed a few goblet cells in the tracheal epithelium. In the bronchi and larger bronchioles, pseudostratified ciliated columnar epithelia were observed. Bronchi were surrounded by segments of cartilage. Distal bronchioles had a simple cuboidal/columnar epithelium with club (Clara) cells, lacked cartilaginous tissue in their walls and had a complete smooth muscle layer. These results revealed histomorphological differences between the ICP and other rodents.
Rezvan Yaghoubfar, Ava Behrouzi, Fatemeh Ashrafian, Arefeh Shahryari, Hamid Reza Moradi, Samira Choopani, Shima Hadifar, Farzam Vaziri, Seyed Ali Nojoumi, Abolfazl Fateh,et al.
Springer Science and Business Media LLC
AbstractSeveral studies have reported that the host-microbe interactions in the gut modulate the host serotonin or 5-hydroxytryptamine (5-HT) system. Here, we evaluated the effects of Akkermansia muciniphila and its extracellular vesicles (EVs) on genes pertaining to the serotonergic system in the colon and hippocampus of mice. Male C57BL/6J mice were administered viable A. muciniphila and its EVs for 4 weeks. The serotonin levels in the colon, hippocampus, and serum of mice, as well as the human colon carcinoma cells (Caco-2), were measured by ELISA assays. Also, the effects of A. muciniphila and its EVs on the expression of serotonin system genes in the colon and hippocampus were examined. A. muciniphila and its EVs may have a biological effect on the induction of serotonin levels in the colon and hippocampus of mice. Also, EVs increased the serotonin level in the Caco-2 cell line. In contrast, both treatments decreased the serotonin level in the serum. Both the bacterium and its EVs had significant effects on the mRNA expression of genes, involved in serotonin signaling/metabolism in the colon and hippocampus of mice. Moreover, A. muciniphila and its EVs affected the mRNA expression of inflammatory cytokines (Il-10 and Tnf-α) in the colon, however, there is no significant difference in inflammatory cell infiltrate in the histopathology of the colon. The presence of A. muciniphila and its EVs in the gut promotes serotonin concentration, they also affect serotonin signaling/metabolism through the gut-brain axis and may be considered in new therapeutic strategies to ameliorate serotonin-related disorders.
Sajad Sahab-Negah, Vahid Hajali, Hamid Reza Moradi, and Ali Gorji
Springer Science and Business Media LLC
Alzheimer’s disease (AD) is described as cognitive and memory impairments with a sex-related epidemiological profile, affecting two times more women than men. There is emerging evidence that alternations in the hippocampal neurogenesis occur at the early stage of AD. Therapies that may effectively slow, stop, or regenerate the dying neurons in AD are being extensively investigated in the last few decades, but none has yet been found to be effective. The regulation of endogenous neurogenesis is one of the main therapeutic targets for AD. Mounting evidence indicates that the neurosteroid estradiol (17β-estradiol) plays a supporting role in neurogenesis, neuronal activity, and synaptic plasticity of AD. This effect may provide preventive and/or therapeutic approaches for AD. In this article, we discuss the molecular mechanism of potential estradiol modulatory action on endogenous neurogenesis, synaptic plasticity, and cognitive function in AD.
Hassan Morovvati, Mohammadkazem Koohi, Zabihollah Khaksar, Freshteh Morshedi, Hojat Anbara, Fatemeh Parsaei, Mehdi Hadijafari, Hamidreza Moradi, , ,et al.
CMV Verlag
Background: Sertraline, along with its beneficial antidepressant effects, may have adverse effects on the fertility and reproductive system. In recent years, the negative effects of sertraline on body tissues have been shown to some extent. This study aimed to investigate the effects of sertraline at different doses on the histological and histometrical structure of ventral and anterior lobes of prostate in adult mice. Materials and Methods: In this experimental study, twenty adult male mice were randomly divided into four groups: control (no treatment) and three groups receiving sertraline at doses of 5, 10 and 20 mg/kg by gavage for 42 days. First, the mice were sacrificed, then, blood samples and prostate lobes tissue were collected for histomorphological and histochemical studies. Results: Results showed a significant decrease in cell count of secretory units in ventral and anterior lobes in the sertraline groups, compared to that in control group (p<0.05). Epithelial thickness showed a significant decrease in ventral and anterior lobes of prostate following the administration of sertraline (20 mg/kg), compared to the control group (p<0.05). A significant dose-dependent decrease was seen in serum testosterone in sertraline groups, compared to the control group (p<0.05). Conclusion: Sertraline has a negative effect on the histopathological and histometrical structure of prostate. However, further clinical studies are required to assess the negative effects of sertraline in human beings.
Fatemeh Ashrafian, Arefeh Shahriary, Ava Behrouzi, Hamid Reza Moradi, Shahrbanoo Keshavarz Azizi Raftar, Arezou Lari, Shima Hadifar, Rezvan Yaghoubfar, Sara Ahmadi Badi, Shohre Khatami,et al.
Frontiers Media SA
Recent evidence suggests that probiotics can restore the mucosal barrier integrity, ameliorate inflammation, and promote homeostasis required for metabolism in obesity by affecting the gut microbiota composition. In this study, we investigated the effect of Akkermansia muciniphila and its extracellular vesicles (EVs) on obesity-related genes in microarray datasets and evaluated the cell line and C57BL/6 mice by conducting RT-PCR and ELISA assays. A. muciniphila-derived EVs caused a more significant loss in body and fat weight of high-fat diet (HFD)-fed mice, compared with the bacterium itself. Moreover, treatment with A. muciniphila and EVs had significant effects on lipid metabolism and expression of inflammatory markers in adipose tissues. Both treatments improved the intestinal barrier integrity, inflammation, energy balance, and blood parameters (i.e., lipid profile and glucose level). Our findings showed that A. muciniphila-derived EVs contain various biomolecules, which can have a positive impact on obesity by affecting the involved genes. Also, our results showed that A. muciniphila and its EVs had a significant relationship with intestinal homeostasis, which highlights their positive role in obesity treatment. In conclusion, A. muciniphila-derived EVs can be used as new therapeutic strategies to ameliorate HFD-induced obesity by affecting various mechanisms.
Bahman Navidshad, Zeinab Maghsoodi, Saeid Nikbin, Vahid Vahedi, Masoud Adibmoradi, Farzad Mirzaei Aghjehgheshlagh, and Hamidreza Moradi
Informa UK Limited
Abstract An experiment with two dietary choline levels (recommended level or 75% of the recommended level) and three dietary garlic powders (0, 5 or 10 g/kg) was conducted on broiler chickens. Three hundred thirty mixed sex 1-day-old Ross 308 broiler chickens were randomly assigned to six dietary treatments, each housed in four replicate pens with 14 birds per pen. Dietary garlic increased the finisher phase’s feed intake. Dietary 10 g/kg of garlic powder and recommended choline level improved body weight gain. Choline deficiency increased feed conversion ratio (FCR). The jejunum villi height was decreased in birds consuming the choline deficient diets; however, villi height was increased by garlic powder. In the duodenum and ileum, 10 g/kg diet garlic powder significantly increased crypt depth compared to those of the treatments with no garlic. This study showed that reducing dietary choline to 75% of the recommended level reduced the growth rate of broilers that could be compensated by dietary garlic. This effect was partly due to higher finisher phase feed intake.
RECENT SCHOLAR PUBLICATIONS
MOST CITED SCHOLAR PUBLICATIONS
Publications
1. Moradi Hamid Reza, Erfani Majd Naeem, Esmaeilzadeh Saleh, Fatemi Tabatabaei Reza. The histological and histometrical effects of Urtica dioica extract on rat’s prostate hyperplasia. Veterinary Research Forum, 2015; 6: 23-29.
2. Masood Adibmoradi, Hamid Reza Moradi, Ali Kalantari hesari, Ghazal Adibmoradi. Study of histomorphometric changes in adult rat's skin following injection of PRP and PPP. Journal of Veterinary Research, 2016; 71(1): 1-8.
3. Hassan Morovvati, Hamid Reza Moradi, Masoud Adibmoradi, Mohammad Taghi Sheybani, Jamileh Salar Amoli. Wheat sprout effects on histological and histometrical structure and sperm parameters in testis of rat exposed to lead. Journal of Veterinary Research, 2017; 72(1): 87-101.
4. Bahman Navidshad, Zeinab Maghsoodi, Saeid Nikbin, Vahid Vahedi, Masoud Adibmoradi, Farzad Mirzaei Aghjehgheshlagh & Hamid Reza Moradi. The compensation effect of dietary garlic on chicken consuming a minimal level of choline. Italian Journal of Animal Science, 2018; 17(1): 1-6.
5. Sajad Sahab Negah, Zabihollah Khaksar, Shahin Mohammad Sadeghi, Naeem Erfanimajd, Sayed Mostafa Modarres Mousavi, Hadi Aligholi, Masoud Adibmoradi, Hamid Reza Moradi*. Effect of nettle root extract on histometrical parameters of cerebral and cerebellar cortices in rat following administration of testosterone. The Neuroscience Journal of Shefaye Khatam, 2015; 3(1): 71-78.
6. Morovvati Hassan, Moradi Hamid Reza, Adibmoradi Masoud, Sheybani Mohammad Taghi, Salar Amoli Jamileh, Kalantari Ali. Effects of wheat sprout extract on the quality of sperm in rats exposed to lead. Iranian Veterinary Journal, 2016; 12(3): 76-85.
7. Sohrab Heydarian, Iraj Pousty, Hamid Reza Moradi. Histomorphological study on prenatal development of spleen in partridge (Alectoris Chukar). Anatomy Science Journal, 2017; 14(1): 15-18.
8. Masoud Adibmoradi, Ali Kalantari Hesari, Hassan Morovvati, Farzad Asadi, Hamid Reza Moradi. Evaluation of sperm quality in mice exposed to camphor and protective role of vitamin E. Journal of Veterinary Research, 2016; 71(2): 237-244.
9. Moradi Hamid Reza, Morovvati Hassan, Adibmoradi Masoud, Najafzadeh Varzi Hosein. The effect of wheat sprout extract on skin injury following injection of lead acetate in rat. Armaghane danesh Journal (Yasuj University of Medical Sciences), 2017; 22 (2): 161-175.
10. Hasan morovvati, Masoud Adibmoradi, Ali Kalantari Hesari, Ramin Mazaheri Nezhad, Hamid Reza Moradi. Effects of camphor on histomorphometric and histochemical parameters of testicular tissue in mice. Iranian Journal of Veterinary Medicine, 2016; 10(3): 225-235.
11. Hasan morovvati, Masoud Adibmoradi, Hamid Reza Moradi, Maziar Taghavi. Detection of herbal tissues in raw meat products using histology method. Veterinary Researches & Biological Products, 2018; 31(1): 123-132.
12. Vahid Hajali, Hamid Reza Moradi, Sajad Sahab Negah. Neurotransmitters play as a key role in adult neurogenesis. The Neuroscience Journal of Shefaye Khatam, 2018; 6(4): 1-14.
13. Naeem Erfani Majd, Hamid Reza Moradi, Parisa Moftakhar. The effects of Urtica Dioica L. root extract on rat testis. Anatomy Science Journal, 2016; 13(4): 225-232.
14. Morovvati Hassan, Moradi Hamid Reza*, Biabani Maysam. Effect of hydroalcoholic extract of wheat sprout on histology and histometry structure of rat's prostate exposed to lead. Iran South Medical Journal. 2018; 20 (6): 540-552.
15. Hassan Morovvati, Zabihollah Khaksar, Mohammad Taghi Sheybani, Hojat Anbara, Mohsen Amini, Hamid Reza Moradi*. Effect of aspartame on histological and histometrical structure of prostate glands in adult mice. Qom University of Medical Sciences Journal, 2019, 12(12): 14-27.
16. Hassan Morovvati, Naeem Erfani Majd, Hamid Reza Moradi, Mehdi Hadi Jafari, Mohammad Mehdi Shamsi, Sajad Chenani. Histological and histochemical study on accessory sex glands of mature native water buffaloes from Khuzestan. Iranian Veterinary Journal, 2019; 15(1): 80-88.
17. Zabihollah Khaksar, Hassan Morovvati, Hamid Reza Moradi, Sajad Sahab Negah. The role of extracellular matrix in myelination and oligodendrogenesis of central nervous system. The Neuroscience Journal of Shefaye Khatam, 2019; 7(2): 66-82.
18. Morovvati H, Koohi M, Khaksar Z, Morshedi F, Anbara H, Parsaei F, Hamid Reza Moradi*. Histological and Histometrical Study of Prostate Following Administration of Sertraline in Adult Mice. Iran South Med J. 2020; 23 (3): 205-221.
19. Sahab-Negah, S., Hajali, V., Hamid Reza Moradi, Gorji, A. The Impact of Estradiol on Neurogenesis and Cognitive Functions in Alzheimer’s Disease. Cell Mol Neurobiol 40, 283–299 (2020).
20. Ashrafian F, Shahriary A, Behrouzi A, Hamid Reza Moradi, Keshavarz Azizi Raftar S, Lari A, Hadifar S, Yaghoubfar R, Ahmadi Badi S, Khatami S, Vaziri F and Siadat SD (2019) Akkermansia muciniphila-Derived Extracellular Vesicles as a Mucosal Delivery Vector for Amelioration of Obesity in Mice. Front. Microbiol. 10:2155. doi: 10.3389/
21. Adibmoradi M, Morovvati H, Hamid Reza Moradi, Sheybani MT, Amoli JS, et al. (2015) Protective Effects of Wheat Sprout on Testicular Toxicity in Male Rats Exposed to Lead. Reprod Syst Sex Disord 4: 156. doi:10.4172/2161-038X.1000156