1986 Specialty: Medicine
Odesa Medical Institute named after E. Pirogov (now Odessa National
Medical University, ONMedU), Odesa
1986 - 1987 Internship in obstetrics and gynecology
Odesa Medical Institute named after E. Pirogov (now Odessa National
Medical University, ONMedU), Odesa
2021 Master's Degree: Public management and administration
Kyiv University for Market Relations, Ukraine, Kyiv
RESEARCH, TEACHING, or OTHER INTERESTS
Obstetrics and Gynecology, Oncology (nursing), Genetics (clinical)
Advancing sexual and reproductive health and rights in wartime Ukraine through international collaboration Kerstin Erlandsson, Valerie Marichereda, Viktoriia Borshch, Iryna Mogilevkina, Kateryna Nitochko, Larysa Klymanska, Liliia Klos, Inna Haletska, Maryna Klimanska, Tetiana Chaban, Halyna Herasym, Catrin Borneskog Sexual and Reproductive Healthcare, 2025 • The war in Ukraine has severely limited access to SRHR services, with millions needing healthcare and support against gender-based violence. • A Swedish-Ukrainian collaboration developed educational programs, an online platform, and peer-learning to strengthen students’ SRHR competencies. • Sweden’s model of comprehensive sexuality education and youth clinics can inspire long-term SRHR reform in Ukraine. • SRHR is a vital component of public health, human rights, and resilience – even during armed conflicts. Dalarna University (Sweden) and three Ukrainian universities in 2023 initiated a collaborative project to strengthen SRHR education in Ukraine through new curricula, an online platform, and peer-learning workshops. The objective of this commentary is to present the project’s approach, implementation, and outcomes, demonstrating how international academic collaboration can strengthen SRHR education and youth consultation services in the context of war and post-war reconstruction. Inspired by Sweden’s comprehensive sexuality education model, the project meets humanitarian needs while supporting reforms. Policy priorities include aligning with UNESCO guidance on sexuality education, integrating adolescent SRHR into healthcare financing, and expanding youth-friendly services.
HYPOGASTRIC SKIN MICROBIOCOENOSES. IS THERE AN ASSOCIATION WITH THE RISK OF POSTOPERATIVE INFECTION? V. H. Marichereda, O. O. Zhurenko Odesa Medical Journal, 2025 The purpose of the study was to assess the state of hypogastric skin microbiocenosis in women with total hysterectomy due to uterine bleeding. Material and methods. The study was conducted on the basis of the clinical divisions of the Department of Obstetrics and Gynaecology of ONMedU in 2020–2022. 34 women aged 35–55 who had total hysterectomy due to uterine bleeding were examined. Women with a normotrophic status (BMI – 18–25 kg/m2, n=11) belonged to group I, with a hypertrophic status (BMI – 25.1–30.0 kg/m2, n=13) – to group II, obese women (BMI more than 30 kg/m2, n=10) – to group III. In the preoperative period, general blood and urine analysis were performed in all patients, the hormonal (FSH, LH, testosterone, prolactin, progesterone, estradiol, leptin) and lipid profile, as well as the composition of the lower abdomen skin microbiocenoses were evaluated. Statistical processing was carried out by methods of dispersion and correlation analysis using Statistica software 14.1.25 (TIBCO, USA). Results. The average BMI in patients of group I was (20.9±0.8) kg/m2, group II – (26.6±0.7) kg/m2, group III – (32.9±1.1) kg/m2 (p<0.05). All women of group III and 7 (53.8%) women of group II showed signs of dyslipidemia. The leptin content in obese patients was (9.2±0.7) ng/ml, significantly higher than the levels achieved in group I (5.3±0.3) ng/ml and group II (6.4±0.4) ng/ml. Conclusions: 1. Qualitative composition of hypogastric skin microbiocenosis depends on nutritional status. 2. A correlation of medium strength was established between the level of estradiol and the detection of opportunistic flora (rs=0.36; p<0.05). The detection rate of opportunistic flora is also correlated with BMI (rs=0.33; p<0.05). 3. The impact of the qualitative composition of hypogastric skin microbiocenosis on the risk of postoperative infectious complications is inconclusive.
Integrating sexual and reproductive health in higher education and healthcare services in Ukraine: A sustainable initiative for empowering war-affected youth Kerstin Erlandsson, Valeriya Marichereda, Larysa Klymanska, Liliia Klos, Inna Haletska, Maryna Klimanska, Daria Drobot, Viktoriia Borshch, Kateryna Nitochko, Iryna Mogilevkina, Xerxes Marcellas Vlahakis, Lavrence Daka, Maya Vergara, Catrin Borneskog Sexual and Reproductive Healthcare, 2025 Integrating Sexual Reproductive Health and Rights (SRHR) into educational programs and healthcare services supports the EU Eastern Partnership and the UN’s Agenda 2030. It is particularly important for youth and young adults who have experienced armed conflict. Photo: Emilia Henriksson. • Our project aims to equip university students with consultation skills to work with war-affected people after graduation. • Advocating for Youth Clinic services that are multi-professional, including midwives, will ensure access to SRHR consultations. • Youth Clinics in any European country where war-affected youth migrate can specifically address their SRHR needs. Integrating Sexual Reproductive Health and Rights (SRHR) into educational programs and healthcare services supports the EU Eastern Partnership and the UN’s Agenda 2030. A Swedish Institute (SI)-funded project empowers undergraduate students in medicine, psychology, and social work to support SRHR among youth and young adults in wartime and post-war Ukraine by incorporating the subject into university curricula. In August 2024, a study tour to Sweden was conducted by managers and faculty from Ukrainian universities, during which the visitors to Sweden identified the need to establish Youth Clinics at Ukrainian universities to address the SRHR needs of the war-affected youth population.
REHABILITATION IN SURGICAL GYNECOLOGY: EXPERIENCE OF A UNIVERSITY CLINIC V. G. Marichereda, S. V. Busel Odesa Medical Journal, 2025 Introduction. Rehabilitation is a critical part of gynecological care, as timely recovery ensures return to normal activity and prevents disability. According to WHO, gynecological morbidity accounts for up to 5.1% of years lived with disability in women of reproductive age, with the majority of cases reported in low-income countries such as Ukraine. Despite advances in surgical techniques, the problem of postoperative rehabilitation in gynecology remains insufficiently studied.The aim of the work. To evaluate the effectiveness of rehabilitation after gynecological surgery under the conditions of a university clinic.Materials and methods. A prospective study was conducted at the Center for Reconstructive and Restorative Medicine during 2021–2024.The outcomes of 86 patients after laparoscopically assisted vaginal hysterectomy were analyzed. Individual rehabilitation programs were designed according to current protocols. Quality of life (QoL) was assessed with HQoL-15D before and after surgery and at 3-month follow- up. A control group included 22 women after hysterectomy without a full rehabilitation course. The mean age of patients was 37.8±0.6 and 38.2±0.9 years, respectively (p>0.05). Statistical analysis used frequency and variance methods (MS Excel).Results and discussion. Postoperative recovery was uneventful in all cases; average hospital stay was 2.2±0.1 days. Women in the rehabilitation group reported significant improvements in pelvic function, daily activity, vitality, sexual activity, and reduction of discomfort and distress (p<0.05). In contrast, control patients more frequently experienced abdominal pain, urinary incontinence, and dyspareunia.Deviations from individual rehabilitation programs negatively affected outcomes.Conclusions. Comprehensive rehabilitation after gynecological surgery significantly improves adaptation and long-term QoL. University clinics provide advantages due to professional capacity, scientific units, and an integrated multidisciplinary environment that ensures effective physical and psychosocial recovery
COMPLICATIONS DURING PREGNANCY ON THE BACKGROUND OF OVERWEIGHT AND OBESITY V. M. Zaporozhan, V. H. Marichereda, L. I. Berlinska, Yu. Yu. Petrovskiy, O. M. Pavlovska, G. L. Lavrynenko Odesa Medical Journal, 2024 The prevalence of overweight and obesity is increasing worldwide; it is one of the leading risk factors for many physical diseases, adversely affecting fertility and pregnancy, especially in countries with a low economic level. According to the World Health Organization, overweight and obesity (BMI ≥30 kg/m2) in women of reproductive age are 39.2% and 15.1%. Overweight and obesity in women of reproductive age are associated with problems with conception, the course of pregnancy, and complications during childbirth. The aim of the study. Based on a literature review of current scientific research, the article aims to analyze the possible risks of complications during pregnancy in overweight and obese women, namely: pregnancy loss, gestational diabetes, gestational hypertension, preeclampsia, premature birth, late birth, and complications during childbirth. Materials and methods. The present article analyzes the scientometric databases of PubMed, Scopus, Web of Science, PMC free article, and Google Scholar from 2018 to 2023. A total of 30 studies covering more than 26 million women in Europe, Asia, the United States and China are included. Results. Being overweight and obese before pregnancy is associated with increased risks of miscarriage, repeated pregnancy loss, gestational diabetes and gestational hypertension, labor will last longer, the risk of induction of labor is increased, and the risk of unplanned caesarean section in active labor is significantly increased, especially in firstborns. Pre-pregnancy overweight and obesity and/or excessive gestational weight gain are high risk factors for moderate, severe, and late-onset preeclampsia. The indicators of the complications listed above are growing in parallel with the indicators of overweight and obesity in the population.
SCENARIO-BASED SIMULATION LEARNING AS A TOOL OF A PROBLEM-BASED APPROACH TO IMPROVING THE QUALITY OF EMERGENCY CARE IN UKRAINE V. H. Marichereda, Т. M. Orabina, О. P. Rogachevskyi, V. I. Borshch, M. P. Pervak, І. P. Аnnienkova, Yu. Yu. Petrovskyi Odesa Medical Journal, 2024 The paper defines the role of scenario-based simulation learning as one of the key tools of a problem-based approach in forming future doctors’ clinical competence, professional confidence, and practical skills in emergency care. The study aims to assess the impact of the introduction of scenario-based simulation learning on the dynamics of changes in the indicators of the formation of professional competence of students in emergency care. Materials and methods. Methods. Descriptive, comparative study, questionnaires, and statistical analysis. Design. The study was carried out between May and June 2023 using emergency simulation situations. 59 sixth-year students of ONMedU took part in the study. Questionnaires and objective assessment criteria were employed to gather information about the participants’ performance in the simulation. Pre-test, post-test right after the simulation, and post-test three months later were used to assess confidence in performing certain medical operations. The answers were then graded using a pre-made mark sheet. Results. Following the simulation, the student’s confidence in all the assessed skills increased significantly, and that rise persisted for three months. The level of confidence of all students for all assessed skills increased significantly immediately after the training (21.8 ±1.33%, p<0.001), after 3 months it remained almost at the same level (19.14±1.54%, p< 0.001). The survival rate of knowledge after 3 months was 18.8±1.71%. Conclusion. The obtained outcomes demonstrate the value of the relevant teaching strategy and its efficiency for Ukrainian higher medical education. It highlights that further study is required to determine the best way to include simulation scenarios in the teaching and learning process.
Biomarkers of placental dysfunction. Clinical experience V.G. Marichereda, O.M. Nadvorna, N.M. Rozhkovska Reproductive Health of Woman, 2024 The objective: to determine the diagnostic value of biomarkers of placental dysfunction at different stages of gestation.Materials and methods. The research was carried out in 2015–2022 on the basis of the municipal non-commercial enterprise “Maternity House No.5” of the Odesa City Council.We analyzed the course and clinical outcomes of pregnancies in 118 women (the main group) who developed and established placental dysfunction (PD) during pregnancy at different stages of gestation. The control group included 78 healthy women whose pregnancies occurred without PD.In women of both groups the frequency of detection of risk factors for PD was assessed by analyzing the content of placental growth factor (PlGF), soluble fms-like tyrosine kinase-1 (sFlt-1) biomarkers in blood serum, Pregnancy-Associated Plasma Protein A (PAPP-A) and β-subunit of chorionic gonadotropin (hCG).Fetal growth retardation was determined by deviations of fetal metric indicators (abdominal circumference, head circumference, biparietal size, thigh length, estimated fetal weight) below the 10th percentile.Statistical processing of the obtained results was carried out using Statistica 14.0 software (TIBCO, USA).Results. Among the examined women of both groups, cases where the pregnancy occurred at the age of 30 years or more and was the first pregnancy that did not end in abortion prevailed. The average age of women in the main group was 33.4±2.3 years, the control group – 29.3±1.4 years.The main group had more women with a history of multiple abortions (odds ratio (OR)=5.6, 95% confidence interval (CI): 1.9–18.8). Disorders of the menstrual cycle in history were found in 39 (33.1%) women of the main group and in 18 (23%) women of the control group (OR=1.6, 95% CI: 0.9–3.2). Concomitant gynecological diseases were represented by uterine fibroids – in 16 (13.6%) pregnant women of the main group and in 8 (10.2%) women of the control group (OR=1.4, 95% CI: 0.6–3.4), benign ovarian tumors – in 13 (11.0%); OR=20.1, 95% CI: 1.2–343.1), mastopathy – in 19 (16.1%; OR=30.8, 95% CI: 1.8–517.6) women of the main group.A significant number of women in the main group had a hypertrophic nutritional status – the body mass index (BMI) at the time of pregnancy was on average 26.7±0.9 kg/m2, women in the control group were represented by the normotrophic type (BMI – 22.2±0.3 kg/m2), in 4 women the indicator was more 30 kg/m2.In the vast majority of pregnant women (68 persons – 57.6%) of the main group the signs of placental malperfusion were registered up to 34 weeks. In 12 (10.2%) cases a primary PD was established.The content of PIGF in women of the main group at the 20th week of pregnancy decreased to 83±4 pg/ml, which is significantly less than the reference values (≥100 pg/ml). On the other hand, in the control group the PIGF concentration was 147±8 pg/ml (p<0.05). The sFlt-1 amount in the main group corresponded to the level of 3395±62 pg/ml. Therefore, the ratio of sFlt-1/PlGF was equal to 40.8±0.4, which is prognostically unfavorable.The PAPP-A indicator, according to monitoring data at the 20th week of pregnancy, was 0.77±0.08 mU/l. In pregnant women with lower values in the future PD occurred earlier. As for the indicators of the β-subunit of hCG, the levels of this hormone in most cases corresponded to the normative values, amounting to an average of 4.7±0.1 IU/l in a pregnancy with a male fetus and 8133±21 IU/l in a pregnancy with a female fetus.Signs of preeclampsia were determined in 22 (18.6%) pregnant women of the main group. The value of the sFlt-1/PlGF ratio in these pregnant women exceeded 50.0.Conclusions. In the vast majority of pregnant women of the main group (68 – 57.6%) the signs of placental malperfusion were found up to 34 weeks. In 22 (18.6%) pregnant women with placental dysfunction (PD) the signs of preeclampsia were detected, the development of which increases when the sFlt-1/PlGF ratio exceeds 50, starting from the II trimester of pregnancy, which is an early biomarker of PD.
CLINICAL AND PATHOGENETIC PARALLELS OF THE HORMONAL PROFILE AND THE QUALITATIVE COMPOSITION OF THE INTESTINAL MICROBIOCENOSIS IN PREGNANT WOMEN V.G. Marichereda, I.O. Adonina, N.M. Rozhkovska Reproductive Endocrinology, 2024 Objective of the study: assessment of clinical and pathogenetic parallels of changes in the hormonal profile and qualitative composition of intestinal microbiocenosis in pregnant women with different nutritional status at different stages of gestation.Materials and methods. 96 pregnant women aged 25–35 with metabolic syndrome (group I), 37 women with obesity of the first degree (group II) and 30 women of the same age with normotrophic nutritional status and physiological course of pregnancy (control group) were examined. Average blood pressure was monitored, the hormonal profile (progesterone, estriol, leptin levels) and lipid profile was assessed, as well as the composition of the intestinal microbiocenosis at 17–20 and 35–37 weeks of gestation.Results. In the period of 17–20 weeks the leptin level in the I group was 38.4 ± 0.7 μg/ml, in the II group – 37.7 ± 1.1 μg/ml, in the control group – 33.2 ± 1.3 μg/ml. In the period of 35–37 weeks its level decreased in all clinical groups, amounting to 112.7 ± 1.4 μg/ml in the I group, 118.3 ± 3.9 μg/ml in the II group, 237 5 ± 5.3 μg/ml in the control group.Cases of the II degree of intestinal dysbiosis prevailed in groups I and II. 65 cases of I degree of dysbiosis and 32 cases of the II degree were found in the I group, 27 and 10 cases in the II group, respectively. 4 (13.3%) pregnant women had II degree of dysbiosis, 12 (40.0%) had I degree of dysbiosis in the control group. The frequency of dysbiosis was correlated with the body mass index (r = 0.82 p < 0.05), the blood content of estradiol (r = 0.49 p < 0.05), progesterone (r = -0.34 p < 0, 05) and leptin (r = 0.69 p < 0.05).Conclusions. The presence of metabolic syndrome and obesity in pregnant women affects the qualitative composition of the intestinal microbiocenosis, which is manifested by an increase in the population of opportunistic microorganisms. The frequency of dysbiosis correlates with the body mass index, estradiol, progesterone and leptin concentrations.
WAYS TO IMPROVE THE PROVISION OF MEDICAL SERVICES THROUGH THE USE OF MECHANISMS FOR MANAGING PERSONNEL CHANGES IN A HEALTHCARE INSTITUTION V. H. Marichereda, V. I. Borshch, V. M. Zhukovska, I. P. Mykolaichuk, M. V. Danilko Odesa Medical Journal, 2024 The article analyzes and systematizes approaches to defining the concepts of “changes”, “organizational changes” and “personnel changes” as scientific categories. The role of changes in personnel management and their significance in the actual use of healthcare institutions is substantiated. The characteristics of personnel changes are determined, and their relationship with the organizational development of a healthcare institution is substantiated. The components of personnel changes in healthcare institutions are studied. Quantitative changes in personnel potential are analyzed and the prerequisites for personnel changes in the healthcare sector are formed. Positions on changes in work with personnel of healthcare institutions in Ukraine are interpreted under legislative documents in the industry. The study is aimed to find and develop ways to improve the process of providing medical services. The authors concluded that a coordinated personnel policy in healthcare should be aimed at managing personnel development, promoting the effective use of personnel potential, increasing the social and professional mobility of medical personnel, and acting as a means for implementing the structural and technological restructuring of both a separate healthcare institution in a territorial community and the industry as a whole. The methodological basis of this study is the Theory of Change (ToC), which underlies the definition of management decisions to eliminate the causes of problems that impede progress effectively, and to choose a management approach, taking into account the comparative advantages of a healthcare institution, indicators of effectiveness, feasibility and uncertainty, which are part of any change process. According to this model, the critical criteria for quality control and assessment are plausibility, feasibility, and testability, with plausibility being fundamental.
Organizational, regulatory and legal aspects of european integration of higher medical education in ukraine: a critical review Wiadomosci Lekarskie Warsaw Poland 1960, 2020
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