Review on compounds and pharmacological activities of Pinus pinaster Ait Abraham Peele K., Venkateswarulu T.C., Sudarsini B., Maneesha N., Indira M. Research Journal of Biotechnology, 2026 Pinus pinaster Ait., commonly known as the maritime pine, is a resilient, fast-growing tree native to the Mediterranean region, capable of reaching heights of up to 40 meters. This species is distinguished by its straight trunk, thick, deeply fissured, fire-resistant bark and vibrant green needles that grow in pairs, extending up to 25 centimeters in length. Its large ovoid cones mature to a glossy brown, measuring up to 20 centimeters long. The maritime pine thrives in sandy, well-drained soils and is widely used in reforestation projects due to its adaptability and resilience. It plays a critical role in stabilizing soil and preventing erosion, particularly in coastal and degraded areas. Additionally, Pinus pinaster forests support biodiversity by providing habitat and food for various wildlife species. Economically, Pinus pinaster is highly valued for its timber and resin. The durable wood is extensively utilized in construction, paper production and furniture-making. The resin, known as rosin or colophony, has applications in numerous industries including adhesives, varnishes and traditional medicine. Furthermore, the essential oils and resins of Pinus pinaster exhibit antiseptic and anti-inflammatory properties, making them beneficial for aromatherapy and topical treatments. The plant extract, known as Pycnogenol®, is a rich source of antioxidants and has been extensively studied for its therapeutic potential in cardiovascular health, skin care and immune system support. This review highlights the diverse bioactive compounds and pharmacological properties of Pinus pinaster, emphasizing its potential applications in medicine and healthcare.
Innovative Techniques for Enhancing Water Treatment Efficiency B. Sumalatha, D. Syam Babu, B. Sudarsini, M. Indira Machine Learning in Water Treatment, 2025 Although three quarters of the earth's surface is covered with water, which is essential for sustaining human life, the availability of fresh water is limited to only about 1%. The global water demand is expected to surge due to population growth, urbanization, industrialization, and changing consumption patterns. As a result, there is increasing pressure on water resources, leading to concerns about water scarcity, pollution, and inadequate access to safe drinking water. Efforts to manage and conserve water resources efficiently are becoming increasingly urgent to ensure sustainable water availability for current and future generations. Various methods have been utilized to analyze and predict water quality and waste water quality, encompassing techniques such as coagulation/flocculation, desalination, membrane filtration, and assessments of biological oxygen demand (BOD) and chemical oxygen demand (COD). These aspects are optimized using machine learning models to improve efficiency, reduce costs, and enhance water quality. Machine learning techniques are applied to waste water treatment processes to optimize parameters such as BOD and COD removal, nutrient removal and sludge treatment. The chapter delves into optimization techniques applied in water treatment processes, aiming to bolster efficiency, reliability, and sustainability. It commences with an introduction to the importance of optimizing water treatment processes, outlining the goals and challenges associated with optimizing various treatment stages such as coagulation, flocculation, filtration, and disinfection. Various methods for optimizing waste water treatment are covered, spanning from traditional to advanced approaches, with a particular focus on leveraging machine learning techniques for enhanced performance. Additionally, the chapter explores emerging trends and future directions in water treatment process optimization, underscoring the potential for ongoing innovation and integration of advanced technologies to tackle evolving water quality challenges.
Scope and Future Prospects of Algal Biomass Toward Pharmaceutical, Nutraceutical, and Agricultural Biotechnology Algal Biomass Technology and Research Sustainable Solutions in Diverse Industries Volume 1 Algal Biomass for Food Agriculture and Pharmaceutical Applications, 2025
Harnessing algal biomass for sustainable energy: cultivation, strain improvement, and biofuel production Indira Mikkili, Bala Venkata Sai Teja Gaddirala, Sudarsini Borugadda, Syam Babu Davuluri Preparative Biochemistry and Biotechnology, 2025 The world faces pressing environmental challenges, including greenhouse gas emissions, global warming, climate change, and rising sea levels. Alongside, these issues, the depletion of fossil fuels has intensified the search for alternative energy sources. Algal biomass presents a promising long-term solution to these global problems. The quest for sustainable energy has driven significant research into algal biofuels as a viable alternative to fossil fuels. Algae offers several advantages as a feedstock for biofuel production, including high biomass yield, rapid growth rates, cost-effective cultivation, carbon dioxide fixation capabilities, and the potential to grow on non-arable land using non-potable water. This manuscript provides an overview of algal biomass cultivation using renewable feedstocks, identifies potential algal strains for biofuel production, and explores bioengineering advancements in algae. Additionally, strain improvement strategies to enhance biofuel yields are discussed. The review also addresses large-scale algal biomass cultivation for biofuel production, assesses its commercial viability, examines challenges faced by the biofuel industry, and outlines prospects for biofuel production using highly potent algal strains. By overcoming and addressing these challenges, algal biofuels have the potential to become a cornerstone of sustainable energy solutions.
Phytochemistry and bioactive potential of water hyssop [bacopa monnieri (l.) wettst.] Phytochemistry and Pharmacology of Medicinal Plants 2 Volume Set, 2023
Phytochemicals and pharmacological activities of tinospora cordifolia (willd.) miers Phytochemistry and Pharmacology of Medicinal Plants 2 Volume Set, 2023
Bioactive compounds and pharmacological activities of mucuna pruriens l. Bioactives and Pharmacology of Legumes, 2023
Screening of ipomoea tuba leaf extract for identification of bioactive compounds and evaluation of its in vitro antiproliferative activity against MCF-7 and HeLa cells Food Technology and Biotechnology, 2020
Screening of antifungal potential of leaf extracts from Albizia Lebbeck (L.) Benth Current Trends in Biotechnology and Pharmacy, 2019
Extraction of phycocyanin from Arthrospira sp. And screening of its antimicrobial potency against the selected pathogenic strains Current Trends in Biotechnology and Pharmacy, 2019
Characterization of bacteriocin producing probiotic properties of enterococcus casseliflavus mi001 isolated from curd sample Current Trends in Biotechnology and Pharmacy, 2019
Morphological and biochemical characterization of Exopolysaccharide producing bacteria isolated from dairy effluent Journal of Pharmaceutical Sciences and Research, 2016
Bioconcrete build buildings with quorum sensing molecules of biofilm bacteria Journal of Pharmaceutical Sciences and Research, 2016
Optimization using central composite design (CCD) for the biosorption of Cr (VI) ions by Azolla filiculoidus a fresh water macro alga Research Journal of Pharmaceutical Biological and Chemical Sciences, 2016
Membrane drug target identification in Mycoplasma Pneumonia-A subtractive genomic approach Research Journal of Pharmaceutical Biological and Chemical Sciences, 2016
Biodiesel from chicken feather meal Journal of Pharmaceutical Sciences and Research, 2015
Isolation and characterization of bacteriocin producing lactic acid bacteria from curd International Journal of Chemtech Research, 2015
Homology modeling studies of human genome receptor using modeller, Swiss-model server and Esypred-3D tools International Journal of Pharmaceutical Sciences Review and Research, 2015
Comparative studies of H5N1 gene segments with other subtypes of influenza- A virus Research Journal of Pharmaceutical Biological and Chemical Sciences, 2014
Review on methods of transesterification of oils and fats in bio-diesel formation International Journal of Chemtech Research, 2014
Biosynthesis and potential applications of bacteriocins Journal of Pure and Applied Microbiology, 2013
Biochemical and molecular characterization of biofilm producing bacteria International Journal of Pharma and Bio Sciences, 2013
Investigation of the potential anti biofilm activities of plant extracts International Journal of Pharmacy and Pharmaceutical Sciences, 2012
RECENT SCHOLAR PUBLICATIONS
Optimization of medium composition for enhanced biomass production of probiotic bacteria using response surface methodology B Sudarsini, M Indira BIOMASS CONVERSION AND BIOREFINERY 16 (2) , 2026 2026
Review on compounds and pharmacological activities of Pinus pinaster Ait NMMI K. Abraham Peele, T.C. Venkateswarulu, B. Sudarsini Research Journal of Biotechnology 21 (1), 370-375 , 2026 2026
Characterization and utilization of eggshell-derived nano-hydroxyapatite for improved plant growth as a fertilizer D Syam Babu, G Jeevana, Y Madhu Babu, P Yaswanth, M Indira Journal of Material Cycles and Waste Management 28, 465–478 , 2026 2026 Citations: 1
Scope and Future Prospects of Algal Biomass Toward Pharmaceutical, Nutraceutical, and Agricultural Biotechnology M Indira, ON Tiwari Algal Biomass Technology and Research, 97-123 , 2026 2026
Trends in cyanobacterial Phycobiliproteins-structure, function, and applications: A review. I Mikkili, S Borugadda, A Kanaparthy International Journal of Biological Macromolecules 331 (Pt 2), 148517-148517 , 2025 2025 Citations: 1
Innovative Techniques for Enhancing Water Treatment Efficiency B Sumalatha, DS Babu, B Sudarsini, M Indira Machine Learning in Water Treatment, 265-291 , 2025 2025 Citations: 1
Significance of Oleaginous Microbes on Value-Added Biomolecule Production M Indira, PS Kavya, KV Prabhakar, ON Tiwari Oleaginous Microbes for Waste Biomass Valorization, 31-60 , 2025 2025
Challenges and Innovations in 3D Printed Bio-organs and Their Materials M Indira, K Abraham Peele, P Angolkar, T Ram Prabhu Challenges and Innovations in 3D Printed Bio-Organs and Their Materials, 149-176 , 2025 2025 Citations: 4
Tissue Engineering Applications of Aloe vera L. Burm. F.: A Comprehensive Review IM Venkateswarulu TC, Naga Lakshmi A, Sudarsini B Regenerative Engineering and Translational Medicine, 1-14 , 2025 2025
Innovative magnetic biochar for textile wastewater treatment: a sustainable solution for methylene blue and Congo Red dye removal S Boddu, M Chavali, JB Dulla, VN Allugunulla, I Mikkili, S Malladi, ... Biomass Conversion and Biorefinery 15 (10), 15399–15415 , 2025 2025 Citations: 12
Harnessing algal biomass for sustainable energy: cultivation, strain improvement, and biofuel production I Mikkili, BVST Gaddirala, S Borugadda, SB Davuluri Preparative Biochemistry & Biotechnology 55 (5), 521-534 , 2025 2025 Citations: 13
Green synthesis of copper oxide nanoparticles (CuONPs) using Ricinus communis: Efficient photocatalytic dye degradation and antibacterial applications S Boddu, BP Marri, RM Katika, I Mikkili, JB Dulla, VN Allugunulla, ... Water, Air, & Soil Pollution 236 (4), 209 , 2025 2025 Citations: 8
Biotechnological exploitation of cyanobacteria and microalgae for bioactive compounds I Mikkili, VP Kodali Biotechnological Intervention in Production of Bioactive Compounds … , 2025 2025 Citations: 1
Medicinal and phytochemical insights into Citharexylum spinosum L.: Exploring bioactive potential of an invasive species MN Indira Medicinal Plants-International Journal of Phytomedicines and Related … , 2025 2025
Laterite integrated persulfate based advanced oxidation and biological treatment for textile industrial effluent remediation: optimization and field application D Syam Babu, K Vijay, S Shakira, VS Mallemkondu, P Barik, C Kuppam, ... Applied Bionics and Biomechanics 2025 (1), 9325665 , 2025 2025 Citations: 2
Optimization and kinetic study of ultrasonic-mediated phycoerythrin extraction from Anabaena sp. PC Nath, TK Bandyopadhyay, N Mahata, S Pabbi, ON Tiwari, M Indira, ... Biomass Conversion and Biorefinery 14 (21), 26779-26790 , 2024 2024 Citations: 9
Advancements in Implantable Medical Textile Materials M Indira, B Sudarsini, B Sumalatha Textile Materials for Good Health and Wellbeing: Design and Applications … , 2024 2024 Citations: 3
Synergistic strategies for cancer treatment: leveraging natural products, drug repurposing and molecular targets for integrated therapy I Mikkili, JK Suluvoy, JJ Thathapudi, K Srirama Beni-Suef University Journal of Basic and Applied Sciences 13 (1), 96 , 2024 2024 Citations: 8
C-phycoerythrin production from Anabaena sp. BTA 903: Optimization, production kinetics, thermodynamic, and stability analysis PC Nath, TK Bandyopadhyay, N Mahata, ON Tiwari, MN Bobby, M Indira, ... Biomass Conversion and Biorefinery 14 (16), 19739-19751 , 2024 2024 Citations: 16
Antibacterial activity of the Allium sativum crude extract against methicillinresistant Staphylococcus aureus. J Pure Appl Microbiol. 2024; 18 (2): 1297-304 M Indira, G Bhuvaneshwari, L Premkumar, P Neelusree Open Access. This article is distributed under the terms of the Creative … , 2024 2024 Citations: 15
MOST CITED SCHOLAR PUBLICATIONS
Molecular docking and dynamic simulations for antiviral compounds against SARS-CoV-2: A computational study KA Peele, CP Durthi, T Srihansa, S Krupanidhi, VS Ayyagari, DJ Babu, ... Informatics in medicine unlocked 19, 100345 , 2020 2020 Citations: 265
Bioactive molecules of probiotic bacteria and their mechanism of action: a review M Indira, TC Venkateswarulu, K Abraham Peele, M Nazneen Bobby, ... 3 Biotech 9 (8), 306 , 2019 2019 Citations: 146
Purification and characterization of bacteriocin produced by Lactobacillus plantarum isolated from cow milk NR Sankar, VD Priyanka, PS Reddy, P Rajanikanth, VK Kumar, M Indira Int J Microbiol Res 3 (2), 133-137 , 2012 2012 Citations: 99
Evaluation of anti-cancer, anti-microbial and anti-biofilm potential of biosurfactant extracted from an Acinetobacter M6 strain AP Karlapudi, TC Venkateswarulu, K Srirama, RK Kota, I Mikkili, ... Journal of King Saud University-Science 32, 223-227 , 2020 2020 Citations: 86
Comprehensive microbiological studies on screening bacteria for self-healing concrete CSS Durga, N Ruben, MSR Chand, M Indira, C Venkatesh Materialia 15, 101051 , 2021 2021 Citations: 72
Plackett-Burman design for screening of process components and their effects on production of lactase by newly isolated Bacillus sp. VUVD101 strain from Dairy effluent AP Karlapudi, S Krupanidhi, R Reddy, NB Md, V TC Beni-Suef University journal of basic and applied sciences 7 (4), 543-546 , 2018 2018 Citations: 68
Isolation, screening and extraction of polyhydroxybutyrate (PHB) producing bacteria from sewage sample J Babu, SB Nath, VP Kodali Int. J. Pharm. Tech. Res 6 (2), 850-857 , 2014 2014 Citations: 62
GC–MS analysis for compound identification in leaf extract of Lumnitzera racemosa and evaluation of its in vitro anticancer effect against MCF7 and HeLa cell lines G Eswaraiah, KA Peele, S Krupanidhi, M Indira, RB Kumar, ... Journal of King Saud University-Science 32 (1), 780-783 , 2020 2020 Citations: 45
Investigation of the potential antibiofilm activities of plant extracts KP Abraham, J Sreenivas, TC Venkateswarulu, M Indira, DJ Babu, ... Int. J. Pharm. Pharm. Sci 4 (4), 282-285 , 2012 2012 Citations: 39
Review on methods of transesterification of oils and fats in bio-diesel formation TC Venkateswarulu, CV Raviteja, KV Prabhaker, DJ Babu, ... Int J ChemTech Res 6 (4), 2568-2576 , 2014 2014 Citations: 37
Estimation of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of antimicrobial peptides of Saccharomyces boulardii against selected … V TC, K Srirama, I Mikkili, JB Dulla, VN Alugunulla, D Sweety, ... Karbala International Journal of Modern Science 5 (4), 8 , 2019 2019 Citations: 34
Isolation and characterization of bacteriocin producing Enterococcus casseliflavus and its antagonistic effect on Pseudomonas aeruginosa M Indira, TC Venkateswarulu, KV Prabhakar, KA Peele, S Krupanidhi Karbala International Journal of Modern Science 4 (4), 361-368 , 2018 2018 Citations: 31
EFFECT OF SULPHUR AND BORON ON THE PERFORMANCE OF SESAME (SESAMUM INDICUM L.) IN ONATTUKARA SANDY SOIL OF KERALA, INDIA. J Mathew, S George, M Indira Indian Journal of Agricultural Research 47 (3) , 2013 2013 Citations: 31
Biosynthesis and potential application of bacteriocins VP Rodali, VK Lingala, AP Karlapudi, M Indira, TC Venkateswarulu, ... J Pure Appl Microbiol 7, 2933-2945 , 2013 2013 Citations: 25
Morphological and biochemical characterization of exopolysaccharide producing bacteria isolated from dairy effluent M Indira, TC Venkateswarulu, K Chakravarthy, AR Reddy, DJ Babu, ... Journal of Pharmaceutical Sciences and Research 8 (2), 88 , 2016 2016 Citations: 21
Isolation and characterization of bacteriocin producing lactic acid bacteria from diary effluent M Indira, TC Venkateswarulu, K Chakravarthy, AR Reddy, KV Prabhakar Res J Pharm Technol 8 (11), 1560-1565 , 2015 2015 Citations: 21
Genetic variability, heritability and genetic advance for yield and its components in sesame ( Sesamum indicum L.). MR Bindu, P Sushamakumari, M Indira, TN Vilasini, S Seeja, ... 2014 Citations: 17
C-phycoerythrin production from Anabaena sp. BTA 903: Optimization, production kinetics, thermodynamic, and stability analysis PC Nath, TK Bandyopadhyay, N Mahata, ON Tiwari, MN Bobby, M Indira, ... Biomass Conversion and Biorefinery 14 (16), 19739-19751 , 2024 2024 Citations: 16
Antibacterial activity of the Allium sativum crude extract against methicillinresistant Staphylococcus aureus. J Pure Appl Microbiol. 2024; 18 (2): 1297-304 M Indira, G Bhuvaneshwari, L Premkumar, P Neelusree Open Access. This article is distributed under the terms of the Creative … , 2024 2024 Citations: 15
Advancing Fermented Food Products: Exploring Bioprocess Technologies and Overcoming Challenges B Sudarsini, TC Venkateswarulu, S Krupanidhi, B Sumalatha, M Indira FOOD AND BIOPROCESS TECHNOLOGY 17, 3461–3482 , 2024 2024 Citations: 14