Ioana Lacatusu

Scopus Publications

Dual Arnica montana and Ruscus aculeatus Hyaluronic Acid-Modified Nanostructured Lipid Carriers for Accelerated Wound Healing Effect
Ioana Lăcătusu, Robert Tincu, Mihaela Bacalum, Diana Lavinia Stan, Ovidiu Cristian Oprea, et al.
Antioxidants, 2026
Skin wound healing involves a delicate balance between proliferation and remodelling processes, with significant therapeutic challenges. The present work aimed to investigate the capacity of hybrid lipid nanocarriers carrying a complex phytochemical profile (HA-NLC-ArnicaM and/or RuscusA extracts) to counteract the destructive action of oxidative free radicals and to accelerate wound closure induced on BJ fibroblast cells. The lipid and hybrid nanocarriers have main diameters ranging from 145 nm to 180 nm, electrokinetic potential between −45 mV and −62 mV, and entrapment efficiency of plant extracts exceeding 96%. HA-NLC-plant extracts exhibit an appropriate level of biocompatibility at concentrations < 50 µg/mL. ArnicaM wins the antioxidant contest while RuscusA proved excellent for accelerating the wound closure process. NLCs and HA-NLCs entrapping ArnicaM manifested the highest capacity to neutralise DPPH free radicals, reaching 79.4% inhibition. BJ fibroblast cells treated with HA-NLCs closed the wound more rapidly than NLCs, with cells reaching maximum wound closure efficiency when treated with 12.5 and 100 µg/mL HA-NLC-RuscusA, followed by HA-NLC-ArnicaM-RuscusA. These results facilitate the design of remarkable hybrid lipid nanocarriers, which exploit the emergence of a pharmacological phytochemical’s synergy, and which could contribute to stimulating signalling pathways and promoting appropriate cellular regeneration, needed for wound healing.
Advanced Hybrid Polysaccharide—Lipid Nanocarriers for Bioactivity Improvement of Phytochemicals from Centella asiatica and Hypericum perforatum
Ioana Lăcătusu, Mihaela Bacalum, Diana Lavinia Stan, Ovidiu-Cristian Oprea, Mihaela Neagu, et al.
Pharmaceutics, 2026
Background/Objectives: Phytochemicals are known to be active contributors to a healthy life, providing valuable wound healing benefits. Methods: This research took an innovative approach that successfully overcame the bioavailability limits of herbal extracts, by entrapping CentellaA with HypericumP in nanostructured lipid carriers (NLCs) and hybrid hyaluronic acid (HA-NLCs) as valuable formulations with enhanced bioactivity. Results: NLCs and HA-NLCs showed excellent entrapping efficiency values for CentellaA and HypericumP ranging from 89.5 to 95.3%. Co-entrapping of CentellaA:HypericumP in a weight ratio of 4:1 and 2:1 led to diameters of 221.4 ± 2.08 nm for NLC-CentellaA-HypericumP and 220.3 ± 1.74 nm for hybrid HA-NLC-CentellaA-HypericumP. The bimodal calorimetric profile of NLCs contributed to a lower degree of lipid core structural organization. HA-NLC-CentellaA showed the safest biocompatibility behavior with BJ skin cells. Conclusions: The cells treated with NLC-CentellaA exhibited a favorable scratch wound closure and promoted the fastest BJ cell migration. NLC- and HA-NLC herbal extracts remodeled the cytoskeleton of BJ fibroblast cells. The morphological fluorescence changes revealed that the fibroblast cells retained intact their cytoskeleton, characteristic of a viable cell with no obvious stress. An active motility of cells treated with NLCs in the wound area was detected, indicating strong pro-migratory properties; e.g., for NLC-CentellaA, the wound was almost closed after 30 h. Designing NLCs with HA adaptability to reinforce the skin wound healing action represents a desired step for the development of herbal products that meets the challenge of combining the benefits of phytochemicals and nanotechnology to create value-added herbal products.
Antimicrobial Efficacy of Green Silver Nanoparticles Synthesized Using Crataegus monogyna Extract
Mihaela Cristina Lite, Roxana Constantinescu, Laura Chirilă, Alina Popescu, Andrei Kuncser, et al.
Biomimetics, 2025
Current demands in the field of functional textiles include the integration of specific characteristics, such as self-cleaning, antimicrobial efficacy and possible wound healing properties. Green synthesis of nanoparticles represents a promising strategy to address these challenges, combining biocompatibility and ecological safety with effective antimicrobial and antioxidant performance. In this study, silver nanoparticles (AgNPs) have been synthesized using different ratios of Crataegus monogyna extract: AgNO3. Physically stable AgNPs with spherical shape, particle main diameters ranging from 61.9 to 85.4 nm and appropriate polydispersity indices were produced. Crataegus monogyna presented high phenolic content (30.58 ± 2.20 mg/g) and strong antioxidant activity (96 ± 1.6 µmol TE/g). The obtained nanoparticles were characterized by TEM, EDX, and XRD analysis. When applied to cotton and wool textiles, the AgNPs adhered uniformly, caused minimal colour change, and exhibited enhanced antimicrobial activity against bacterial and fungal strains compared to other plant-derived AgNPs, with values between 8 and 13.5 mm. The treated textiles demonstrated strong performance against Staphylococcus aureus with inhibition zones of 11 ± 0.53 for cotton and 13.5 ± 0.42 for wool. These findings highlight the potential of Crataegus monogyna-based AgNPs as effective and fabric-compatible antimicrobial agents.
Ginkgo Biloba and Green Tea Polyphenols Captured into Collagen–Lipid Nanocarriers: A Promising Synergistically Approach for Apoptosis Activation and Tumoral Cell Cycle Arrest
Mirela Mihaila, Nicoleta Badea, Marionela Birliga, Marinela Bostan, Madalina Georgiana Albu Kaya, et al.
International Journal of Molecular Sciences, 2025
Considering the world’s growing interest in health-promoting phytochemicals, the current research investigated the development of a dual-captured Ginkgo Biloba and Green Tea Extract into Collagen-Nanostructured Lipid Nanocarriers (Col-NLC-GBil-GTE) for an enhanced therapeutic efficacy against hepatic, colon or breast cancer. NLC considerably reduced cell viability; the most advanced cytotoxicity profile was determined on human colon adenocarcinoma cells (LoVo) and liver cancer cells (HepG2), e.g., tumor cell viability was 21.81% in the presence of Col-NLC-GBil-GTE, similar to that determined for Cisplatin. Col-NLC exhibited apoptosis in HepG2 and LoVo cells and no significant apoptosis induction in normal HUVECs. A 20% increase in apoptosis for HepG2 cells was registered for 100 μg/mL NLC-GBil-GTE compared to Cisplatin (Cis-Pt), e.g., a 63.4% total apoptosis for NLC-GBil-GTE versus a 52.6 apoptosis induced by 100 μg/mL of a chemotherapeutic drug. According to the cell cycle outcomes, an accumulation of hepatocyte HepG2 tumor cells in the G0/G1 phase was detected upon treatment with 100 mg/mL of NLC- and Col-NLC-GBil-GTE, simultaneously with a drastic decrease in the S phase, which may indicate a cell number reduction that enters in the division cycle. The simultaneous delivery of GBil and GTE by synchronizing their bioactivities offers several advantages; Col-NLC-GBil-GTE can be viewed as a noteworthy strategy for consideration in connection with antitumor therapeutic protocols.
Hybrid Carbohydrate–Lipid Nanocarriers: In Vitro Efficacy Gene-Rated by Association of UV-Absorbers and Raspberry Polyphenols Rich-Fraction
Nicoleta Badea, Diego Samayoa, Alina Moroşan, Cristina Ott, Ioana Lacatusu
Pharmaceuticals, 2025
Background/Objectives: The study aims to investigate an improved version of lipid nanocarriers (NLCs) (formulated with functional coconut butter and marula oil) by designing hyaluronic acid (HA) decorated NLC co-loaded with dual UVA (butyl methoxy dibenzoyl methane, BMDBM), UVB absorbers (ethyl-hexyl-salicylate, EHS) and a Raspberry rich polyphenols fraction (RPRF) for development of more natural NLC-based to-pical formulations. Methods: Quality and quantitative attributes of classic- and HA-NLC have been assigned based on particle size, electrokinetic potential, encapsulation efficiency, spectroscopic characteristics, and high-resolution mass spectrometry. To establish the performance profile of antioxidant activity, release of active substances, sun blocking action, and photostability, in vitro studies were conducted. Results: NLC with an average size of ~150 nm and zeta potentials < −39.5 mV showed 80% and 93.1% of encapsulation efficiency for BMDBM and EHS, and up to 83% for natural RPRF. A long-lasting release of absorbers, with a maximum cumulative release of 2.1% BMDBM and 4.6% EHS was detected. NLC-UV Abs-RPRF-HA assured 72.83% radical scavenging activity. The IC50 for HA-NLC-UV Abs-RPRF was 6.25-fold lower than NLC-UV Abs-HA, which reflects the greater free radical scavenging action. The conditioned NLC–UV Abs-RPRF-HA cream was able to provide a sun protection factor value of 52 and UVA-PF value of 81, which underlines an impressive removal of both categories of UVA and UVB radiation. A significant photoprotective upregulation, four-fold for the topical formulation with NLC-UV Abs-RPRF-HA, resulted after a simulated irradiation process. Conclusions: HA decorated-NLC-conditioned creams might provide a useful platform for developing na-tural and sophisticated dermal delivery systems, for influencing skin permeability, and for synergistically imparting antioxidant and photoprotective actions to cosmetic pro-ducts.
Hybrid Albumin-Decorated Lipid-Nanocarrier-Mediated Delivery of Polyphenol-Rich Sambucus nigra L. in a Potential Multiple Antitumoural Therapy
Robert Tincu, Mirela Mihaila, Marinela Bostan, Daniela Istrati, Nicoleta Badea, et al.
International Journal of Molecular Sciences, 2024
The current research attempted to address the suitability of bioactive Sambucus nigra extract entrapped in albumin-decorated nanostructured lipid carriers (NLCs) as a promising “adjuvant” in improving tumour penetration for multiple antitumour therapy. The new hybrid albumin-decorated NLCs were characterised based on, e.g., the particle size, zeta electrokinetic potential, SambucusN entrapment efficiency, and fluorescence spectroscopy and tested for different formulation parameters. The antioxidant activity of NLC-SambucusN was significantly enhanced by a bovine serum albumin (BSA) polymer coating. According to the real-time cell analysis (RTCA) results, NLC-I–SambucusN–BSA behaved similarly to the chemotherapeutic drug, cisplatin, with cell viability for LoVo tumour cells of 21.81 ± 1.18%. The new albumin–NLC–SambucusN arrested cancer cells in G1 and G2 cycles and intensified the apoptosis process in both early and late phases. An advanced induction, over 50% apoptosis in LoVo colon cells, was registered for 50 μg/mL of NLC-II-SambucusN-BSA, a fourfold increase compared to that of untreated cells. RTCA and flow cytometry results showed that concentrations of the hybrid NLC–SambucusN up to 50 μg/mL do not affect the proliferation of normal HUVEC cells. This approach provides insightful information regarding the involvement of phytochemicals in future therapeutic strategies. Albumin-decorated NLCs can be considered a noteworthy strategy to be connected to antitumour therapeutic protocols.
PRE-FORMULATION, FORMULATION AND PILOT SCALE-UP STUDIES TO ESTABLISH THE QUALITATIVE AND QUANTITATIVE COMPOSITION OF AN INNOVATIVE NANOFORM DIETARY SUPPLEMENT FOR MENOPAUSAL THERAPY
Farmacia, 2024
Safety of Innovative Nanotechnology Oral Formulations Loaded with Bioactive Menopause Molecules: Influence of Genotoxicity and Biochemical Parameters on a Menopausal Rat Model
Simona Crișan, Anca Lucia Pop, Ioana Lacatusu, Nicoleta Badea, Cosmin Mustaciosu, et al.
Nutrients, 2023
In recent years, nanoparticles have gained significant importance due to their unique properties, such as pharmacological, electrical, optical, and magnetic abilities, contributing to the growth of the science and technology sector. Particular naturally derived biomolecules with beneficial effects on menopause disorder have been the subject of studies of pharmaceutical formulation to obtain alternative pharmaceutical forms with increased bioavailability and without side effects, as in nanostructured lipid carriers (NLCs) loaded with such active ingredients. In the present study, one stage of a broader project, we have performed pharmacotoxicology studies for six combinatory innovative nanocapsule pharmaceutical forms containing active natural biomolecules before considering them as oral formulas for (1) in vitro toxicity studies on culture cells and (2) in vivo preclinical studies on a surgically induced menopause model of Wistar female rats, and the influence of the NLCs on key biochemical parameters: lipid profile (TG, Chol, HDL), glycemic markers (Gli), bone markers (Pac, Palc, Ca, phosphorus), renal markers (Crea, urea, URAC), inflammation (TNF), oxidative stress (GSH, MDA), and estrogen–progesterone hormonal profile. The micronucleus test did not reveal the genotoxicity of the tested compounds; the menopause model showed no significant safety concerns for the six tested formulas evaluated using the blood biochemical parameters; and the results showed the potential hypoglycemic, hypolipidemic, hypouricemic, and antioxidant potential of one of the tested formulas containing nano diosgenin and glycyrrhizic acid.
Phytochemical Synthesis of Silver Nanoparticles and Their Antimicrobial Investigation on Cotton and Wool Textiles
Mihaela Cristina Lite, Roxana Constantinescu, Elena Cornelia Tănăsescu, Andrei Kuncser, Cosmin Romanițan, et al.
Materials, 2023
The use of bio-based reagents for silver nanoparticle (AgNP) production has gained much attention among researchers as it has paved the way for environmentally friendly approaches at low cost for synthesizing nanomaterials while maintaining their properties. In this study, Stellaria media aqueous extract was used for silver nanoparticle phyto-synthesis, and the resulting treatment was applied to textile fabrics to test its antimicrobial properties against bacteria and fungi strains. The chromatic effect was also established by determining the L*a*b* parameters. For optimizing the synthesis, different ratios of extract to silver precursor were tested using UV-Vis spectroscopy to observe the SPR-specific band. Moreover, the AgNP dispersions were tested for their antioxidant properties using chemiluminescence and TEAC methods, and the phenolic content was evaluated by the Folin-Ciocâlteu method. For the optimal ratio, values of average size, 50.11 ± 3.25 nm, zeta potential, −27.10 ± 2.16 mV, and polydispersity index, 0.209, were obtained via the DLS technique and zeta potential measurements. AgNPs were further characterized by EDX and XRD techniques to confirm their formation and by microscopic techniques to evaluate their morphology. TEM measurements revealed cvasi-spherical particles with sizes in the range of 10–30 nm, while SEM images confirmed their uniform distribution on the textile fiber surface.
Polygonum cuspidatum Loaded Nanostructured Lipid Carriers for Dual Inhibition of TNF-α- and IL-6 Cytokines and Free Radical Species
Teodora-Alexandra Iordache, Nicoleta Badea, Mirela Mihaila, Simona Crisan, Anca Lucia Pop, et al.
Materials, 2023
The main objective of this study was the testing of natural compounds, such as Polygonum cuspidatum (PgnC) loaded into nanostructured lipid carriers (NLC), which can act as a “double-edged sword” aimed at simultaneously combating dangerous free radicals and inhibiting pro-inflammatory cytokines. Resveratrol-rich PgnC extract was paired with another phytochemical, Diosgenin (DSG), in NLC. The lipid nanocarriers carrying both herbals (NLC-DSG-PgnC) had spherical diameters (100 ± 2 50 nm), a polydispersity index of ~0.15, and electrokinetic potentials greater than −46.5 mV. Entrapment efficiencies of 65% for PgnC and 87% for DSG were determined by chromatographic and UV-Vis spectroscopy assays. Cell cytotoxicity analysis proved that 50 µg/mL of NLC-PgnC and dual-NLC ensured a biocompatible effect like the untreated cells. The dual-NLC assured a much slower in vitro release of DSG and PgnC (67% PgnC and 48% DSG) than the individual-NLC (78% PgnC and 47% DSG) after 4 h of experiments. NLC encapsulating PgnC presented a superior ability to capture cationic radicals: 74.5 and 77.9%. The chemiluminescence results pointed out the non-involvement of DSG in stopping oxygenated free radicals, while the antioxidant activity was maintained at a level higher than 97% for dual-NLC. NLC-DSG-PgnC ensured a promising capacity for inhibition of pro-inflammatory cytokine IL-6, ranging from 91.9 to 94.9%.
Novel Bovine Serum Albumin-Decorated–Nanostructured Lipid Carriers Able to Modulate Apoptosis and Cell-Cycle Response in Ovarian, Breast, and Colon Tumoral Cells
Robert Tincu, Mirela Mihaila, Marinela Bostan, Florina Teodorescu, Daniela Istrati, et al.
Pharmaceutics, 2023
Influence of basil oil extract on the antioxidant and antifungal activities of nanostructured carriers loaded with nystatin
Gabriela Badea, Alin Gabriel Bors, Ioana Lacatusu, Ovidiu Oprea, Camelia Ungureanu, et al.
Comptes Rendus Chimie, 2023
COMPARATIVE DISSOLUTION STUDY OF A SOLID PHARMACEUTICAL FORM CONTAINING NANOSTRUCTURED LIPID CARRIER (NLC) INCORPORATING DIOSGENIN – CONVENTIONAL VERSUS BIORELEVANT DISSOLUTION MEDIA
ANCA LUCIA POP
Farmacia, 2023
Design of Green Silver Nanoparticles Based on Primula Officinalis Extract for Textile Preservation
Mihaela Cristina Lite, Rodica Roxana Constantinescu, Elena Cornelia Tănăsescu, Andrei Kuncser, Cosmin Romanițan, et al.
Materials, 2022
Salicin and Hederacoside C-Based Extracts and UV-Absorbers Co-Loaded into Bioactive Lipid Nanocarriers with Promoted Skin Antiaging and Hydrating Efficacy
Ioana Lacatusu, Brindusa Balanuca, Andrada Serafim, Cristina Ott, Mariana Prodana, et al.
Nanomaterials, 2022
THE INFLUENCE OF VEGETABLE OIL AND SELF-ORGANIZING AGENTS’ COMPOSITION ON OBTAINING STABLE NANOSTRUCTURED LIPID CARRIERS
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2022
CURCUMIN CO-LOADED WITH A LIPID MEDIATOR IN THE SAME NANOSTRUCTURED LIPID DELIVERY SYSTEM
LUCIA MARINA CRISTINA COC
Farmacia, 2022
Challenges in coopted hydrophilic and lipophilic herbal bioactives in the same nanostructured carriers for effective bioavailability and anti-inflammatory action
Teodora-Alexandra Iordache, Nicoleta Badea, Mirela Mihaila, Simona Crisan, Anca Lucia Pop, et al.
Nanomaterials, 2021
Multifaced role of dual herbal principles loaded-lipid nanocarriers in providing high therapeutic efficacity
Ioana Lacatusu, Teodora Alexandra Iordache, Mirela Mihaila, Dan Eduard Mihaiescu, Anca Lucia Pop, et al.
Pharmaceutics, 2021
Effective Lipid Nanocarriers Based on Linseed Oil for Delivery of Natural Polyphenolic Active
Lucia Marina Cristina Coc, Ioana Lacatusu, Nicoleta Badea, Marcela Elisabeta Barbinta-Patrascu, Aurelia Meghea
Journal of Nanomaterials, 2021
The association effect of cocoa butter with vegetable oils on the obtaining of lipid nanocarriers loaded with antidepressant and antipsychotic drugs
Aurelia BRATU, Cristina OTT, Brindusa BALANUCA, Nicoleta BADEA, Ioana LACATUSU, et al.
Revue Roumaine De Chimie, 2021
Azelaic acid-willow bark extract-panthenol – Loaded lipid nanocarriers improve the hydration effect and antioxidant action of cosmetic formulations
Laura Vasilica Arsenie, Ioana Lacatusu, Ovidiu Oprea, Natalita Bordei, Mihaela Bacalum, et al.
Industrial Crops and Products, 2020
Synergism of plant extract and vegetable oils-based lipid nanocarriers: Emerging trends in development of advanced cosmetic prototype products
I. Lacatusu, D. Istrati, N. Bordei, M. Popescu, A.M. Seciu, et al.
Materials Science and Engineering C, 2020
The association effect of cocoa butter with vegetable oils on the obtaining of lipid nanocarriers loaded with antidepressant and antipsychotic drugs
Revue Roumaine De Chimie, 2020
Advanced bioactive lipid nanocarriers loaded with natural and synthetic anti-inflammatory actives
I. Lacatusu, N. Badea, G. Badea, M. Mihaila, C. Ott, et al.
Chemical Engineering Science, 2019
Improved anti-obesity effect of herbal active and endogenous lipids co-loaded lipid nanocarriers: Preparation, in vitro and in vivo evaluation
I. Lacatusu, N. Badea, D. Udeanu, L. Coc, A. Pop, et al.
Materials Science and Engineering C, 2019
New cosmetic formulations with broad photoprotective and antioxidative activities designed by amaranth and pumpkin seed oils nanocarriers
Ioana Lacatusu, Laura Vasilica Arsenie, Gabriela Badea, Ovidiu Popa, Ovidiu Oprea, et al.
Industrial Crops and Products, 2018
Marigold extract, azelaic acid and black caraway oil into lipid nanocarriers provides a strong anti-inflammatory effect in vivo
I. Lacatusu, G. Badea, M. Popescu, N. Bordei, D. Istrati, et al.
Industrial Crops and Products, 2017
Naringenin improves the sunscreen performance of vegetable nanocarriers
Gabriela Badea, Nicoleta Badea, Lorelei I. Brasoveanu, Mirela Mihaila, Raluca Stan, et al.
New Journal of Chemistry, 2017
Phyto-mediated nanostructured carriers based on dual vegetable actives involved in the prevention of cellular damage
D. Istrati, I. Lacatusu, N. Bordei, G. Badea, O. Oprea, et al.
Materials Science and Engineering C, 2016
Ivy leaves extract based - Lipid nanocarriers and their bioefficacy on antioxidant and antitumor activities
I. Lacatusu, N. Badea, G. Badea, L. Brasoveanu, R. Stan, et al.
Rsc Advances, 2016
Exploitation of amaranth oil fractions enriched in squalene for dual delivery of hydrophilic and lipophilic actives
Cristina Ott, Ioana Lacatusu, Gabriela Badea, Iulia Adriana Grafu, Daniela Istrati, et al.
Industrial Crops and Products, 2015
Lipid nanocarriers based on natural oils with high activity against oxygen free radicals and tumor cell proliferation
I. Lacatusu, N. Badea, G. Badea, O. Oprea, M.A. Mihaila, et al.
Materials Science and Engineering C, 2015
New approach to prepare willow bark extract-lipid based nanosystems with enhanced antioxidant activity
Elena Mitrea, Ioana Lacatusu, Nicoleta Badea, Cristina Ott, Ovidiu Oprea, et al.
Journal of Nanoscience and Nanotechnology, 2015
Integrative approach in prevention and therapy of basal cellular carcinoma by association of three actives loaded into lipid nanocarriers
Gabriela Badea, Ioana Lacatusu, Cristina Ott, Nicoleta Badea, Iulia Grafu, et al.
Journal of Photochemistry and Photobiology B Biology, 2015
Use of various vegetable oils in designing photoprotective nanostructured formulations for UV protection and antioxidant activity
Gabriela Badea, Ioana Lăcătuşu, Nicoleta Badea, Cristina Ott, Aurelia Meghea
Industrial Crops and Products, 2015
Influence of basil oil extract on the antioxidant and antifungal activities of nanostructured carriers loaded with nystatin
Gabriela Badea, Alin Gabriel Bors, Ioana Lacatusu, Ovidiu Oprea, Camelia Ungureanu, et al.
Comptes Rendus Chimie, 2015
Lipid nanocarriers based on natural compounds: An evolving role in plant extract delivery
Ioana Lacatusu, Nicoleta Badea, Gabriela Niculae, Natalita Bordei, Raluca Stan, et al.
European Journal of Lipid Science and Technology, 2014
Physicochemical characterization and use of heat pretreated commercial instant dry baker's yeast as a potential biosorbent for Cu(II) removal
Ana‐Maria Stanescu, Ligia Stoica, Carolina Constantin, Ioana Lacatusu, Ovidiu Oprea, et al.
Clean Soil Air Water, 2014
Design of soft lipid nanocarriers based on bioactive vegetable oils with multiple health benefits
Ioana Lacatusu, Gabriela Niculae, Nicoleta Badea, Raluca Stan, Ovidiu Popa, et al.
Chemical Engineering Journal, 2014
Photostability enhancement by encapsulation of α-tocopherol into lipid-based nanoparticles loaded with a UV filter
Gabriela Niculae, Ioana Lacatusu, Alin Bors, Raluca Stan
Comptes Rendus Chimie, 2014
A systematic methodology to design silica templates: Silica microemulsion formulation and nanodroplet type and size estimation
Maria Mihaly, Ioana Lacatusu, Nicoleta-Liliana Olteanu, Aurelia Meghea
Comptes Rendus Chimie, 2014
Influence of vegetable oil on the synthesis of bioactive nanocarriers with broad spectrum photoprotection
Gabriela Niculae, Ioana Lacatusu, Nicoleta Badea, Aurelia Meghea, Raluca Stan
Central European Journal of Chemistry, 2014
Rice bran and raspberry seed oil-based nanocarriers with self-antioxidative properties as safe photoprotective formulations
Gabriela Niculae, Ioana Lacatusu, Nicoleta Badea, Raluca Stan, Bogdan Stefan Vasile, et al.
Photochemical and Photobiological Sciences, 2014
Optimization of lipid nanoparticles composition for sunscreen encapsulation
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2013
Coencapsulation of butyl-methoxydibenzoylmethane and octocrylene into lipid nanocarriers: UV performance, photostability and in vitro release
Gabriela Niculae, Nicoleta Badea, Aurelia Meghea, Ovidiu Oprea, Ioana Lacatusu
Photochemistry and Photobiology, 2013
Lipid nanoparticles based on omega-3 fatty acids as effective carriers for lutein delivery. Preparation and in vitro characterization studies
Ioana Lacatusu, Elena Mitrea, Nicoleta Badea, Raluca Stan, Ovidiu Oprea, et al.
Journal of Functional Foods, 2013
Antioxidant activity of solid lipid nanoparticles loaded with umbelliferone
I. Lacatusu, N. Badea, A. Murariu, O. Oprea, D. Bojin, et al.
Soft Materials, 2013
Lipase immobilisation on new silica-based supports
Journal of Environmental Protection and Ecology, 2012
Novel bio-active lipid nanocarriers for the stabilization and sustained release of sitosterol
I Lacatusu, N Badea, R Stan, A Meghea
Nanotechnology, 2012
Nanoencapsulation of natural productswith multifunctional properties in silicaand hybrid organic - silica host matrices
Natural Products Structure Bioactivity and Applications, 2012
Lipid nanoparticles based on butyl-methoxydibenzoylmethane: In vitro UVA blocking effect
G Niculae, I Lacatusu, N Badea, A Meghea
Nanotechnology, 2012
Collector reagents for heavy metal ions separation from polluted aqueous systems
Journal of Environmental Protection and Ecology, 2012
Time series model applied to environmental monitoring data analyses
Journal of Environmental Protection and Ecology, 2012
Evaluation of monitoring of lead emissions in Bucharest by statistical processing
Journal of Environmental Protection and Ecology, 2012
Highly antioxidant carotene-lipid nanocarriers: Synthesis and antibacterial activity
Ioana Lacatusu, Nicoleta Badea, Oprea Ovidiu, Dionezie Bojin, Aurelia Meghea
Journal of Nanoparticle Research, 2012
Cu(II) separation from diluted aqueous solutions by flotation with atypical collectors anti and syn 2-hydroxy-3,5-di-tert-butyl-benzaldoxime
L. Stoica, I. Lacatusu
International Journal of Environment and Waste Management, 2012
Cryoprotector effect on main properties of lipid nanoparticles loaded with bio-active compounds
Journal of Optoelectronics and Advanced Materials, 2012
Nanostructures with liposomes and carbon nanotubese
Journal of Optoelectronics and Advanced Materials, 2011
Effect of vanadium on new silsesquioxane-nano silica encapsulated bio-active compounds with potential for bio-medical application
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2011
Vegetal nanoclusters in hybrid silica films prepared by sol-gel spin coating technique
I. Lacatusu, N. Badea, A. Murariu, C. Pirvu, A. Meghea
Journal of Non Crystalline Solids, 2011
Nanoencapsulation of natural products with multifunctional properties in silica and hybrid organic-silica host matrices
Biocompatible Nanomaterials Synthesis Characterization and Applications, 2011
The encapsulation effect of uv molecular absorbers into biocompatible lipid nanoparticles
Ioana Lacatusu, Nicoleta Badea, Alina Murariu, Aurelia Meghea
Nanoscale Research Letters, 2011
New organic - Inorganic hybrid materials for enzymes immobilization
Revista De Chimie, 2011
Evaluation of carbon monoxide pollution in bucharest and potential risks for human health. part I
Journal of Environmental Protection and Ecology, 2010
Separation of Cu(II) from water by flotation with hydroxyaromatic chelating collectors
Revista De Chimie, 2010
Spectral characterization of model systems containing lipids and chlorophyll
Marcela Elisabeta Barbinta Patrascu, Laura Tugulea, Ioana Lacatusu, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2010
Effect of UV sunscreens loaded in solid lipid nanoparticles: A combinated SPF assay and photostability
Ioana Lacatusu, Nicoleta Badea, Alina Murariu, Dionezie Bojin, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2010
Silica polymeric networks templated with D-fructose - As host matrices for natural extracts immobilization
Ioana Lacatusu, Nicoleta Badea, Dionezie Bojin, Ion Iosub, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2010
Antioxidant capacity of lipid nanoparticles loaded with rosemary extract
I. Lacatusu, N. Badea, A. Murariu, C. Nichita, D. Bojin, et al.
Molecular Crystals and Liquid Crystals, 2010
Encapsulation of fluorescence vegetable extracts within a templated sol-gel matrix
Ioana Lacatusu, Nicoleta Badea, Rodica Nita, Alina Murariu, Florin Miculescu, et al.
Optical Materials, 2010
Synthesis of high fluorescent silica hybrid materials by immobilization of orange peel extract in silica-silsesquioxane matrix
I. Lacatusu, N. Badea, R. Nita, M. Giurginca, D. Bojin, et al.
Journal of Physical Organic Chemistry, 2009
Parchment behaviour under extreme heat and fire conditions
M. Giurginca, I. Lacatusu, L. Miu, I. Petroviciu
Materials Research Innovations, 2009
Role of silsesquioxane compounds used as 'building blocks' in sol-gel nanoencapsulation of retinyl palmitate
I. Lacatusu, R. Nita, N. Badea, D. Bojin, A. Meghea
Materials Research Innovations, 2009
Novel fluorescence nanostructured materials obtained by entrapment of an ornamental bush extract in hybrid silica glass
Ioana Lacatusu, Nicoleta Badea, Dionezie Bojin, Silvia Iosub, Aurelia Meghea
Journal of Sol Gel Science and Technology, 2009
Effect of surfactants on stability of colloidal sols as precursors in sol-gel encapsulation
Ioana Lacatusu, Nicoleta Maria Badea, Aurelia Meghea
Key Engineering Materials, 2009
Examination of kinetic flotation process for two experimental Cu(II) and Ni(II) - α-benzoinoxime systems, based on kinetic literature models
Revista De Chimie, 2009
Environmental monitoring of co emissions: Statistical character of acquired data
Irina Meghea, Mihaela Mihai, Ioana Lacatusu, Tiberiu Apostol
Environmental Engineering and Management Journal, 2009
Hybride nanomaterials based on silica coated C60 clusters obtained by microemulsion technique
Maria Mihaly, Ioana Lacatusu, Ioan Alexandru Enesca, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2008
Fe2O3 nanoparticles coated in a SiO2 shell by microemulsion method
Ioana Lacatusu, Maria Mihaly, Ioan Alexandru Enesca, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2008
Evaluation of lead pollution in Bucharest. Part II: Theoretical aspects of risk management strategy for impact of lead on human health
Mihaela Mihai, Ioana Lacatusu, Alina Murariu, Aurelia Meghea
Environmental Engineering and Management Journal, 2008
Sulphonephtalein chromophore as molecular probe in micelle systems
Revista De Chimie, 2007
Cu(II) separation from aqueous solutions by ionic flotation with 2-hydroxy-5- nonyl benzaldoxime collector
Revista De Chimie, 2007
Flotation separation of Ni(II) from diluted aqueous systems with α - Benzoinoxime collector
Revista De Chimie, 2006
Sinteza 2-hidroxi-5-nonilbenzaldoximei şi a acidului N-(2-hidroxi-5-nonilbenzil) aspartic, potenţiali colectori în flotaţia ionicǎ
Revista De Chimie, 2005

Ioana Lacatusu

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